Skip to content
View in the app

A better way to browse. Learn more.

The Antidepressant Harm and Recovery Forum

A full-screen app on your home screen with push notifications, badges and more.

To install this app on iOS and iPadOS
  1. Tap the Share icon in Safari
  2. Scroll the menu and tap Add to Home Screen.
  3. Tap Add in the top-right corner.
To install this app on Android
  1. Tap the 3-dot menu (⋮) in the top-right corner of the browser.
  2. Tap Add to Home screen or Install app.
  3. Confirm by tapping Install.

Interaction between anti-inflammatory drugs and SSRIs

Featured Replies

Antidepressant effects of selective serotonin reuptake inhibitors (SSRIs) are attenuated by antiinflammatory drugs in mice and humans

 

Link to the study: HERE

 

The study suggests that the way in which the body responds to the effects of SSRI drugs is altered by anti-inflammatory drugs.

 

Members may wish to consider this when tapering- NSAIDs are common, over the counter (non-prescription) drugs in many countries and it would be easy to assume that they are harmless. As always, it is worth thinking about whether any other medications being taken might be interacting with a psychiatric medication being tapered.

 

I would (and did) take this into consideration when I had long since stopped taking Mirtazapine and was suffering from severe PAWS- I actively avoided other pharmaceutical drugs to help my body return to baseline.

 

It is not clear cut, but clearly there are interactions between psychiatric medications and other common pharmaceutical drugs, and it is best to keep this in mind.

Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all.

 

Perhaps you should consider this post an artistic work of fiction written for entertainment purposes.


Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants

 

15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects)

Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise

1 month taper  to 0mg

Last dose April 2023

Severe withdrawal syndrome with many physical symptoms

Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.

  • Luke locked and unlocked this topic

Create an account or sign in to comment

Account

Navigation

Search

Search

Configure browser push notifications

Chrome (Android)
  1. Tap the lock icon next to the address bar.
  2. Tap Permissions → Notifications.
  3. Adjust your preference.
Chrome (Desktop)
  1. Click the padlock icon in the address bar.
  2. Select Site settings.
  3. Find Notifications and adjust your preference.