June 14Jun 14 I came across a concept called Central Governor Fatigue, where the brain will physiologically change how the body perceives energy levels so the body slows down to prevent injury, for example risk of injuries or over training. I asked Chat GPT if this happens on a psychological level in addition to a physical level. I strongly relate to this concept outlined below.Yes, the concepts behind the Central Governor Model apply directly to psychological stress, chronic overthinking, and trauma, though the mechanism manifests as emotional and cognitive burnout rather than physical pacing. Because the brain is a single, integrated processing unit, it cannot separate intense psychological load from physical threat. It uses the same "governor" mechanism to throttle your energy when your mental and emotional systems face catastrophic overload. 1. The "Cross-Talk" of Mental and Physical FatigueThe brain does not have a separate energy pool for running and thinking. A heavily taxed mind directly compromises physical and mental capacity. Shared Brain Regions: The Anterior Cingulate Cortex (ACC) plays a massive role in both physical effort and processing emotional pain, conflict, and stress. When overthinking or trauma exhausts the ACC, it triggers a protective shutdown. Perceived Exertion Spikes: Studies show that when individuals are mentally fatigued by stressful tasks before a physical workout, their muscles perform perfectly at a cellular level, but their Rate of Perceived Exertion (RPE) skyrockets. The brain forces them to slow down early because the baseline psychological load is already too high. 2. Extreme Stressors and HomeostasisThe Central Governor Model is built on preserving homeostasis (internal balance). Extreme psychological stress destroys this balance by flooding your body with cortisol and adrenaline. The Brain's Calculation: If you are constantly overthinking, experiencing panic, or enduring high-stress environments, your brain views this state as an emergency threat to your systemic health.The Shutdown Response: To protect you from systemic collapse, the governor triggers symptoms like profound lethargy, apathy, anhedonia (inability to feel pleasure), or executive dysfunction. It forces a "freeze" state to mandate rest. 3. Psychological Injuries and Safety MarginsIn physical training, the central governor operates with a "safety margin"—it stops you well before your muscles actually tear or your heart fails. Psychological injuries, like PTSD or severe burnout, fundamentally alter where the brain sets that safety margin. Hyper-Vigilance Lowering the Threshold: After a psychological injury, the brain becomes hyper-vigilant to threat. It assumes resources are scarce and danger is high. Premature Fatigue: As a result, the governor resets your threshold much lower. A minor task or a standard daily stressor that you used to handle easily will now trigger an intense wave of exhaustion, as your brain frantically tries to protect your fragile emotional state from further injury. Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mgCURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day) ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.010 & still holding Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.
June 14Jun 14 Very interesting @Catbird , thanks for sharing. Aug 2006 - Sertraline 25/50/75/100mg TO June 2019 - Reduced from 100mg to 50mg over a few monthsSept 2019 - Reduced from 50mg to 25mg lasted a week, then went back up to 50mg, after a few weeks back up to 100mg.Oct 2021 - Reduced to 75mg, Dec 2021 (mid) reduced to 50mg , March 2022 - Reduced to 25mgOct 2022 - Reduce to 0mg (Immediate withdrawal crying, mood unstable, impending doom, digestive probs, tingling,numbness,burning, brain zaps, insomnia)Feb 2023 - "Panic attack" lasting 14 hours, 2 weeks later start back on 25mg sertraline, 12 hours later severe 'panic attack' with chest pain, tachycardia, restlessness, hyponatraemia, impending doom, racing thoughts, akathisia mild. Taken to emergency. March 2023 back up to 50mg (on medical advice), April 75mg, May 100mg. Back to 75mg within a few weeks due to feeling too stimulated and anxious. Nov 2023 resume taper. 70, 65, 60, 55, 50 (March 2024)April 45mg, May 41mg, June 37mg, July 34mg Aug 31mg, Sept 28mg, Oct 26mg, Nov 25mg, HOLD Jan 1st 2025 24mg, Jan 12th 23.5mg, Jan 20th 23mg, Feb 20th 22mg, March 20th 21mg, April 14th 18.9mg, May 5th 17mg, May 28th 15.3mg, July 16th 13.7mg, Aug 26th 12.3mg, Sept 16th 10.5 mg, Sept 22, 10mg, Oct 7th 8.3mg, Nov 4th 8mg, Dec 1st 7.7mg, Dec 26th 7mg 2026 Updose to 7.2mg Mar 20th, Back to 7mg Mar 21. Currently holding Other supplements: Fish oil, Mg citrate/glycinate 150-300mg per day, Ginkgo biloba daily, womens multi vit/min 3 times week, Vitamin C 1000mg night, valerian/passiflora as needed. B12 as needed. Bone support for osteopaenia (Ca/Mg, K, D)
June 20Jun 20 Fatigue was a huge issue for me in WD - and still is an issue to be honest. Its amazing the toll these drugs take on your system and energy levels. Mirtazapine Recommended by doctor due to severe ear pain. Was on 30 mg from September 2021 to February 2022. Suffered severe bad reaction of akathisia with pacing and emotional deadness. Tapered from 30mg going down 7.5mg every 2 weeks until last 7.5mg tapered 2.5mg every 2 weeks. Yeah it was fast but I just had to get off this stuff. Completely off from April 2022. Feeling hugely better but still have weird feeling, muscle aches and tiredness.
June 20Jun 20 Very interesting and very relatable for me as I experience the freeze response to stresses. So, what can we do to alleviate this? I can only think of meditation or mindfulness to help lessen to perceived threat. How do we reassure (or trick) our brains that there's no actual threat? Current dose is 0.14mg Citalopram Tapering details from start to December 2025 are saved here: Mamgu: reducing citalopram - Introductions and updates - Surviving Antidepressants. Citalopram 20mg from 2014.2019 28th Nov 9mg. 2020 13th Jan 8.1mg. 11th Feb 7.3mg. 29th April 2020 6.57mg. 30th May 5.90mg. 21st July 5.31mg. 17th Sept 4.8mg. 2021 7th Feb 4.3mg. 29th Mar 3.8mg. 10th May 3.42mg. 19th June 3.12mg. 29th Sept 2.83mg. 10th Nov 2.55mg. 2022 7th Jan 2.3mg. 15th Feb 2.07mg. 15th Mar 1.87mg. 7th May 1.68mg. 20th June 1.5mg. 24th Sept 1.43mg. 12th Oct 1.35mg. 12th Nov. 3rd Dec 1.25mg. 2023 4th Feb 1.097mg. 27th Mar 0.988mg. 8th May 0.89mg. 19th June 0.8mg. 14th Sept 0.72mg. 2024 1st Jan 0.71mg. 8th Jan 0.70mg. 15th Jan 0.69mg. 22nd Jan 0.68mg. 29th Jan 0.66mg. 5th Feb 0.64mg. 12th Feb 0.6mg. 19th Feb 0.56mg. 25th Mar 0.52mg. 1st Apr 0.49mg. 8th Apr 0.47mg. 15th Apr 0.44mg. 22nd Apr 0.42mg. 29th Apr 0.4mg. 27th May 0.38mg. 3rd June 0.36mg. 17th June 0.34mg. 10th August 0.32mg. 2nd Sept 0.3mg. 15th Sept 0.28mg. 1st Oct 0.26mg. 15th Nov 0.24mg. 16th dec 0.22mg. 2025 23rd Jan 0.2mg. 23rd June 0.196mg. 30th Jun 0.192mg. 7th July 0.188mg. 14th July 0.184mg. 21st July 0.18mg. 14th Oct 0.176mg. 2nd Nov 0.172mg. 10th Nov 0.168mg. 1st Dec 0.164mg. 25th Dec 0.16mg 2026 26th Jan 0.156mg. 2nd Mar 0.152mg. 16th Mar 0.148mg. 23rd March 0.144mg. 6th Apr 0.14mg
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