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Dahlia2: Severe withdrawal after long term use Zoloft and almost CT.

Featured Replies

Thank you for the opportunity to come here from SA.

 

I took zoloft 20 years, long term it made me sick. I had an adverse reaction which led to CT (jumped off from 12,5mg after 5 months taper from 50mg).

I got very sick and tried to reinstate after 3 months which didn't work. I lived with my perents first 1,5 year with severe withdrawal, feels like neurological injury.

Today I’am 2 years and 2 months off and slightly improved but still in difficult withdrawal injury.

It will take a long time so I am grateful for support and contact with others in the same situation as it is a lonely and difficult situation to be in.

 

This is my thread on SA: https://www.survivingantidepressants.org/profile/22292-dahlia50/

2002 Zoloft 25mg (2008 50mg)

2022 May - Dr wanted to increase to 62,5mg. Felt sick, went back to 50mg efter 2 weeks.

2022 Oct - Reducing dose to 37,5mg (from 50mg). WD in few days, advised to go back to 50 - I then got adverse paradoxical reaction 

2022 Oct - Zoloft 50mg adverse reaction

2023 May 5th - Reducing dose to 25mg (directly from 50mg by Dr, difficult WD).

2023 Aug 1st - Reducing dose to 12,5mg 

2023 Oct 10th - Removed dose from 12mg to zero by Dr. Reinstated 2,5mg citalopram after 3 months, bad reaction. Reinstated 0,5mg zoloft for 6 days after 7 months, didn’t work. In terrible WD.

Welcome to the forum, Dahlia2.

 

I am the Recovery Assistant Bot and I am here to post some information for you whilst we await replies from other members.

 

This is a volunteer-run, community forum aimed at helping those who are experiencing difficulties with psychiatric medications. If you are experiencing an adverse reaction to them, withdrawal difficulties or are injured by them, we are very sorry to hear this and will do what we can to help you.

 

While we are waiting for human members to reply, there are some things you can do that will help you get the most out of this forum whilst you await further support.

 

Please familiarise yourself with the forum rules and the disclaimer located here:

https://antidepressantrecovery.org/misc.php?action=help

 

Please update your signature. This will allow members to see some basic information about your drug history and situation so that they may help you best. Information on how to do this is located in the guides linked above, but here is a direct link:

https://antidepressantrecovery.org/misc.php?action=help&hid=8

 

Once this is done, future posts made by you will have this signature turned on by default.

 

If you have migrated here from "SurvivingAntidepressants" feel free to post a link to your old thread in this one, or include it in your signature.

 

We hope that you will find this forum helpful.

Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all.

 

Perhaps you should consider this post an artistic work of fiction written for entertainment purposes.


Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants

 

15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects)

Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise

1 month taper  to 0mg

Last dose April 2023

Severe withdrawal syndrome with many physical symptoms

Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.

Hi Dahlia2

 

Welcome to the forum!

 

Im sorry to read about your reaction to Sertraline. That was a tricky situation to be in hurts to stay on the drug and now hurts to jump off. Im truly sorry for this experience and my heart goes out to you. Im glad you can see some progress although slow, I think this is a good sign. I hope and very much expect further progress as time passes as that is what is observed in the community as a whole.

 

I also hope this site is useful to you and offers you community and support as you recover.

 

Again welcome we are very happy to see you here.

 

Chippy

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

Hey Dahlia, it’s good to see you here! Welcome, and I look forward to following your continued journey here. ☺️

 

Much like yourself I too also experienced a pretty severe adverse reaction in the past so I and many others from here and SA share your pain. 

 

It’s good to see you’ve made some improvements and continue holding onto faith and hope that you WILL continue to heal, it may be slow and gruelling but you won’t be like this forever, I promise. Took me a good 7-8 months to really feel like I was mostly back from my ADR from an antibiotic right in the middle of my withdrawal experience, I still have sleeping issues that stem from it today but I’m hoping for a full recovery eventually.

  • March 2017 - ADR to Prochlorperazine (Stemetil) treatment because of vertigo & vestibular dysfunction.

  • December 2017/January 2018 - started Sertraline (Zoloft) @ 25mg, then 50mg after 4 weeks.

  • March/April 2018 - went from 50 milligrams to 100mg, and stabilised. 

  • 2021 - experienced tachyphylaxis (poop out) and went from 100mg to 200 mg. Was neurotoxic for 7 months before going back to 100mg next day. 

  • May 2023 - prescribed Agomelatine & Omeprazole to go alongside Sertraline.

  • October 2023 - cold turkey off Agomelatine and Omeprazole, and cut SSRI from 100-50mg, withdrawal began 4 days later.

  • December 2023 - was cross tapered from Sertraline and onto Venlafaxine XR @ 37.5mg increased to 75mg 4 weeks later.

  • July 2024 - tapered off Venlafaxine XR 75mg over 4 weeks to completely heal from protracted withdrawal, been drug free since this period.

  • December 2024 - had a brutal setback from antibiotic + antiviral use. Took 4-5 months to recover to my "normal" baseline.

  • Author

Thank you Chippy!

I feel like I’m the only one who didn’t taper more slowly after so many years. But didn’t know you could get injured like this. After my reaction I got scared and went to hospital - they should have been more careful when Dr took me off but they didn’t have the knowledge.

It’s still hard but I’m trying to hang in there. 

I’m thankful to be here where I can talk to others who understand. Just the feeling that you are not alone in having experienced this horrible thing caused by SSRI.

 

/D.


Thank you Jack for kind words!

It's really not a straight healing line, hope often fades but I try to hang in there anyway. It helps to Have kind souls who understand what this is.

2002 Zoloft 25mg (2008 50mg)

2022 May - Dr wanted to increase to 62,5mg. Felt sick, went back to 50mg efter 2 weeks.

2022 Oct - Reducing dose to 37,5mg (from 50mg). WD in few days, advised to go back to 50 - I then got adverse paradoxical reaction 

2022 Oct - Zoloft 50mg adverse reaction

2023 May 5th - Reducing dose to 25mg (directly from 50mg by Dr, difficult WD).

2023 Aug 1st - Reducing dose to 12,5mg 

2023 Oct 10th - Removed dose from 12mg to zero by Dr. Reinstated 2,5mg citalopram after 3 months, bad reaction. Reinstated 0,5mg zoloft for 6 days after 7 months, didn’t work. In terrible WD.

Welcome aboard Dahlia2!

 

I am pretty active now since I am off of work for the next 2 weeks and trying to establish things here as best I can over from SA. I hope to figure out my signature soon and post some coping information. 

 

We are all in some part of this crazy journey that will one day be the best healed, success story all of us will know. There will celebrations for all of us!

 

Hugs and <3

2 Tim 1:7 For God did not give us a spirit of cowardice (fear); but rather of power and love and self-control (a sound mind).

The Whole Story About Me

--Current Rx: since 2000-2025 Levothyroxine discontinued late Sept 2025 under DO supervision--no menstrual cycle for 2 months, Hypothalamus PMG brought it back and has been regular ever since under functional chiropractor =o) thank God for holistic medicine

2017-current Remeron/Mirt. recent taper schedule here: crushed pills 0.45mg May 30, 2025; 0.4mg Sept 14, 2025; found out 0.4mg weighed is actually a dose of 0.44mg Dec 19, 2025 and now using compounded Rx; 0.41mg Feb 27, 2026; 0.39mg April 3, 2026, 0.38mg May 8, 2026, 0.37mg June 28, 2026.

--Supplements: Standard Process-Whole Food Folate, Prolamine Iodine Plus, B Vitality w/ CoQ10, Zypan, RNA, Cataplex E, Symplex F, and Immuplex (sort of like a multi but for Oct-Apr) when needed; Biotics Research- Mg-Zyme 100mg; Omega-3 Oil, Black Currant Seed Oil, Vitamin D3/K2 drops; sometimes Seeking Health methyl free multi vitamin and elderberry zinc gummies

**Love my work, fitness, polyvagal exercises (includes yoga-style poses for nervous system regulation), prayer/Inner Healing Prayer, holistic health, somatic therapies, lovingkindness, forest therapy, singing, helping others, spending time in nature and with family and friends.

Anti-histamine Withdrawal Video-Explains a lot (This is not me.)

  • Author

Thank you Namastejen1!

 

Yes it is a crazy and painful jouney.

I will take a little christmas brake even though the symptoms don’t.

Season’s Greetings to everyone here.

2002 Zoloft 25mg (2008 50mg)

2022 May - Dr wanted to increase to 62,5mg. Felt sick, went back to 50mg efter 2 weeks.

2022 Oct - Reducing dose to 37,5mg (from 50mg). WD in few days, advised to go back to 50 - I then got adverse paradoxical reaction 

2022 Oct - Zoloft 50mg adverse reaction

2023 May 5th - Reducing dose to 25mg (directly from 50mg by Dr, difficult WD).

2023 Aug 1st - Reducing dose to 12,5mg 

2023 Oct 10th - Removed dose from 12mg to zero by Dr. Reinstated 2,5mg citalopram after 3 months, bad reaction. Reinstated 0,5mg zoloft for 6 days after 7 months, didn’t work. In terrible WD.

Hi Dahlia, thank you for your post on my thread, it's good that you're here too. We both seem to be in protracted withdrawal with horrible symptoms. There seems to be a few others here too in a similar situation to ours. It will be good to chat if you find it helpful.

2008, 10 mg citalopram, 2.5 mg bendroflumethiazide. 

2021 reduced citalopram over 3 years and stayed on 5.2 mg citalopram for approx. 1 year. 

Sept 2023 taken off all meds and put on amitriptyline 10 mg and Ramipril 2.5 mg. 

October 2023 taken off amitriptyline and ramipril and put on propranolol 10 mg and Losartan 25 mg. 

November 2023 taken off propranolol and losartan. 

December 2023 back on citalopram 0.5 mg and bendroflumethiazide 2.5 mg. 

February 2024 taken off bendroflumethiaide put on bisoprolol 1.25 mg but came off it same month. Put on ramipril 1.25 mg, still on citalopram 0.5 mg. Stopped ramipril same month. Decided to quit all meds.

June 2024 0.45 mg citalopram

July 2024 0.4 mg citalopram

October 2024 0.2 mg citalopram but had to increase to 0.3 mg same month

January 2025 quit citalopram at 0.3 mg CT.

Not taking any prescription meds currently, health checks have been good results to date.

Hi Dahlia 

 

No you’re not alone. Sooo many folk have come off too quickly or CTd. We pretty much always got poor advice from our doctors. I’d like to say things are changing. And they are. But it’s still very likely you will receive incorrect advice even here in the uk where there has been some improvements many gps and other medical professionals are not up to speed. I hope in time this will change.

 

I’m glad you’ve found us. I hope this will be a home for exactly that. Support and understanding where we might otherwise struggle to get this from other sources.

 

Chippy

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

Thank you for joining.

 

I didn't start to notice a clear trend towards improvement until nearly 2 years off. I still don't live independently at 2 years and 8 months off.

 

It is good that you have begun to improve, even though it has been a lot of time. I hope the coming months bring more improvements for you and you turn a corner.

Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all.

 

Perhaps you should consider this post an artistic work of fiction written for entertainment purposes.


Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants

 

15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects)

Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise

1 month taper  to 0mg

Last dose April 2023

Severe withdrawal syndrome with many physical symptoms

Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.

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