Skip to content
View in the app

A better way to browse. Learn more.

The Antidepressant Harm and Recovery Forum

A full-screen app on your home screen with push notifications, badges and more.

To install this app on iOS and iPadOS
  1. Tap the Share icon in Safari
  2. Scroll the menu and tap Add to Home Screen.
  3. Tap Add in the top-right corner.
To install this app on Android
  1. Tap the 3-dot menu (⋮) in the top-right corner of the browser.
  2. Tap Add to Home screen or Install app.
  3. Confirm by tapping Install.

Przemek: Trintellix Brintellix terrible headache pls help

Featured Replies

In February, I started taking Brintellix/Trintellix at a dose of 5 mg, gradually increasing it to 20 mg. This medication didn't help me at all. I also constantly felt a terrible pressure and throbbing in my left temple, so much so that I had to stop taking it. Now I'm starting my third week without the medication, but the headache is still throbbing, painful, and feels like pressure on the left side. I also have a twitching eyelid. Has anyone experienced this symptom and will it go away? Please help. I'm afraid I have cancer. It feels like this medication is increasing the pressure in my head and temple. I'm going crazy; no pills are helping.

Dutilox

Tianesal

Escitil

Pregabalinum

Setraline

Trintellix

  • Chippy changed the title to Przemek: Trintellix Brintellix terrible headache pls help

Hi @Przemek

Welcome to the forum!

 

This is a volunteer-run, community forum aimed at helping those who are tapering and/or experiencing difficulties with psychiatric medications and withdrawl syndrome. We are not medical professionals and cannot offer medical advice. We simply offer support and opinions which you could use as talking points with a medical provider knowledgeable in withdrawing off psychiatric medications.

 

Please familiarise yourself with the forum rules and the disclaimer located here: Guidelines

 

Please make sure your signature is kept up to date with your drug history. This will allow members to see some basic information about your drug history and situation so that they may help you best. Information on how to do this is located in the FAQs section above, but here is a direct link: Update Signature

Once this is done, future posts made by you will have this signature turned on by default. For this reason please keep it clear but condensed as possible.

Please use the format outline here Preferred signature/drug history format


I'm so sorry to read about the tough time you've had recently you will find plenty of support here for sure.

10 minutes ago, Przemek said:

In February, I started taking Brintellix/Trintellix at a dose of 5 mg, gradually increasing it to 20 mg. This medication didn't help me at all.

Can you tell us why you started taking this please? Could you also tell us more about your history with antidepressants and other psych drugs? We keep this history in our signatures as requested above.

11 minutes ago, Przemek said:

I also constantly felt a terrible pressure and throbbing in my left temple, so much so that I had to stop taking it.

Was this a new reaction to taking this drug or was this something you were trying to treat with the drug? You haven't been taking the drug long, but stopping these kinds of drugs abruptly isn't advised.

13 minutes ago, Przemek said:

Now I'm starting my third week without the medication, but the headache is still throbbing, painful, and feels like pressure on the left side. I also have a twitching eyelid. Has anyone experienced this symptom and will it go away? Please help. I'm afraid I have cancer. It feels like this medication is increasing the pressure in my head and temple. I'm going crazy; no pills are helping.

Head pressure is a common symptom of WD/injury from psych drugs. It is always a good idea to get checked out if you are worried but I think it highly likely what you are experiencing is from a drug injury, based on the little you have told us.

Pills are not the answer unfortunately, once injured by these drugs more drugs only makes things worse. I would strongly suggest you not take anymore.

 

I look forward to you telling us some more about what has happened to you and more detail about your drug history.

In the mean time this is what I would do if I were you:

 

-Stay Hydrated 

 

-Eat a good clean whole food diet, avoiding processed foods and sugars.

 

-Stay away from caffeine, alcohol and antihistamines and any other psychoactive substances.

 

Supplements are to be avoided initially, as they often irritate our nervous systems. Try to get your nutrition through food.

 

Down the line, you may wish to introduce Fish Oil and Magnesium. Those who can tolerate them have found them calming to the nervous system. Be careful try one at a time and start low and see how you get on should you choose to try them.

 

A daily walk is very important as much as you can manage, if you can manage it. Gets you your fresh air and Vitamin D does wonders for your mind!

 

You are very welcome here and I hope you find the site supportive.

Chippy

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

Welcome @Przemek .

Im sorry you are currently feeling bad due to adverse reaction to the drug.

It may take some time to heal from the effects of the drug, but I assure you, you will be fine, people heal from these drugs, and you do not have cancer, if you really want to, you could get tested just to make sure, but it's 99% likely to not be cancer.

If you would like to cope with this better, I recommend you read the various topics we have on the coping methods section.

You will be fine, trust us and god ♥️

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 
Feel free to mention me whenever help is needed.

 

Current Supplements: Night: 6mg melatonin and 133mg magnesium glycinate. Taking Omega 3 as needed to calm dyskinesia or over stimulation (Lately been reacting more negatively to supplement Omega 3).

Current Medications: Mirtazapine, Lasea (lavender oil) before bed.

------------------------------------------

Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mg

Note: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.

Create an account or sign in to comment

Account

Navigation

Search

Search

Configure browser push notifications

Chrome (Android)
  1. Tap the lock icon next to the address bar.
  2. Tap Permissions → Notifications.
  3. Adjust your preference.
Chrome (Desktop)
  1. Click the padlock icon in the address bar.
  2. Select Site settings.
  3. Find Notifications and adjust your preference.