September 14Sep 14 my first time on here (and not too competent on computers).In 1996 I had depression after a year out of work. I didt ask for treatment and it lifted rapidly when back in work. In 2002 I gave up smoking and refused to start again. After a few months i felt worse and got panic attacks. I was then put on meds and had to start smoking again. Now I am changing from escitalopram to sertraline. I am now 76 and have given up cutting down since its not worth spending my twighlight years in discomfort. I am getting tension headaches as I experience flushes of adrenaline. This seems to be the residue of the panics I used to get. Later, if I may, I will put some questions to your forum --------- those that the typical GP cannot/hasnt got time to answer.Thankyou. Edited September 15Sep 15 by Lighty 20+yrs on ADs.`09 went on citalopram`18 went on sertraline`23 went on escitalopramAug `26 now changed to sertraline (again).Was on 10mg escitalopram now on 125mg sertraline
September 15Sep 15 Welcome to the forum! This is a volunteer-run, community forum aimed at helping those who are tapering and/or experiencing difficulties with psychiatric medications and withdrawl syndrome. We are not medical professionals and cannot offer medical advice. We simply offer support and opinions which you could use as talking points with a medical provider knowledgeable in withdrawing off psychiatric medications. Please familiarise yourself with the forum rules and the disclaimer located here: Guidelines Thank you for updating your signature, I do need you to update if possible which dose of escitalopram you been on from 2023-2026, and which dose of Sertraline are you taking now. Direct link to signature Update: Update Signature (If it's too hard, you can just type it in a comment, but signature update would be preferred with a bit more details)I'm so sorry to read about the tough time you've had recently you will find plenty of support here for sure.10 hours ago, Wilf said:In 1996 I had depression after a year out of work. I didt ask for treatment and it lifted rapidly when back in work. In 2002 I gave up smoking and refused to start again. After a few months i felt worse and got panic attacks. I was then put on meds and had to start smoking again.yep sounds common how they always prescribe meds.10 hours ago, Wilf said:I am now 76 and have given up cutting down since its not worth spending my twighlight years in discomfort.that's a valid reason to choose to stay on the SSRI for the rest of your life, I truly get it, I respect your decision.10 hours ago, Wilf said:I am getting tension headaches as I experience flushes of adrenaline. This seems to be the residue of the panics I used to get. Later, if I may, I will put some questions to your forum --------- those that the typical GP cannot/hasnt got time to answer.yeah, so the thing is with those drugs, everytime you do a change, you irritate the nervous system more, even with both of those drugs you been on being SSRI's, they still work a little bit different on the central nervous system, so it's not the exact same puzzle piece so to speak.How bad are your symptoms from 1-10 ? I would honestly say, my opinion would probably be to just stay on the Sertraline, just make sure to never change your SSRI to a different one in the future, you would be asking for more trouble if you keep switching your SSRI's.Your symptoms currently are not your 'mental illness', they are symptoms of destabilization of the nervous system from the changes with the drugs.You will slowly have your symptoms improve as you keep holding the same dosage with your Sertraline, it's normal for symptoms to get better or worse at times. The Windows and Waves Pattern of StabilizationIn the mean time this is what I would do if I were you: -Stay Hydrated -Eat a good clean whole food diet, avoiding processed foods and sugars. -Stay away from caffeine, alcohol and antihistamines and any other psychoactive substances. Supplements are to be avoided initially, as they often irritate our nervous systems. Try to get your nutrition through food. Down the line, you may wish to introduce Fish Oil and Magnesium. Those who can tolerate them have found them calming to the nervous system. Be careful try one at a time and start low and see how you get on should you choose to try them. A daily walk is very important as much as you can manage, if you can manage it. Gets you your fresh air and Vitamin D does wonders for your mind! You are very welcome here and I hope you find the site supportive. Edited September 15Sep 15 by Lighty I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. Feel free to mention me whenever help is needed. Current Supplements: Night: 6mg melatonin and 133mg magnesium glycinate. Taking Omega 3 as needed to calm dyskinesia or over stimulation (Lately been reacting more negatively to supplement Omega 3).Current Medications: Mirtazapine, Lasea (lavender oil) before bed.------------------------------------------Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mgNote: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.
September 15Sep 15 Hey @Wilf Welcome to the forum. Glad you found us. Ask away mate. :) I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.Please take the time to do it today 🙂 https://yellowcard.mhra.gov.ukFor US members details here.
September 16Sep 16 @Wilf welcome to the forum.We'd be happy to discuss any questions you have as best we can. We're not medical professionals, and everybody is different in terms of how they react to these drugs. Having said that, across this forum and a multitude of other prescribed harm forums, we do have the benefit of thousands of patient experiences, so we can share what we have learned from that in the context of what's happening to you.Unfortunately changing between drugs can be problematic just like cutting down doses can. Are you able to share the reason behind changing drugs at this stage? Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all. Perhaps you should consider this post an artistic work of fiction written for entertainment purposes. Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants 15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects) Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise 1 month taper to 0mg Last dose April 2023 Severe withdrawal syndrome with many physical symptoms Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.
September 29Sep 29 Author Hello, I was on 10mg escitalopram and felt it was failing. Although 20mg is max dose, the licence means only 10mg can can be given to pensioners. 20+yrs on ADs.`09 went on citalopram`18 went on sertraline`23 went on escitalopramAug `26 now changed to sertraline (again).Was on 10mg escitalopram now on 125mg sertraline
September 29Sep 29 3 hours ago, Wilf said:Hello, I was on 10mg escitalopram and felt it was failing. Although 20mg is max dose, the licence means only 10mg can can be given to pensioners.Ok, thanks for explaining that @Wilf. I understand that you don't want to come off the drugs, which is completely fair given the toll it can take on us, but switching drugs quickly like you did can cause harm to our nervous system as well. How are you feeling these days? I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. Current regimen:Cymbalta - 90 mg/daySeroquel - 12.5 mg/day*holding to stabilize as of Apr 2026 History:Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to presentCymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper offZoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present
October 1Oct 1 Author Dear Sarah, Thanks for asking about my welfare. At the end of July I started changing from 10mg escitalopram/day to sertraline. For 2 wks I was given 50mg sert every day and 10mg esc every other day. Then 50mg sert only. I was impatient and raised it to 75, then 100 over 2 wks, and then after 3 wks more I raised it to 125 . I did this in the belief that I could increase at a much faster pace than reducing. I have been on 125 for a month now and starting to improve. The tension headaches have reduced although my head is still ringing. I know that diagnosis and cause must be very complex. But I feel that ignorance breeds frustration which breeds anxiety. I read a simple explanation of how distraction works and it has been so useful to me. I read that there is no cure for a damaged autonomic , but I would love to understand how and why ------ it might be useful in coping. At every turn I have been denied psychiatric referral which might have been good in coping.I am lucky in that my case is relatively minor compared to some I have seen on here. I would like to see GPs read some of the testimonies on here --- it would open their eyes.But I will keep on taking the tablets and wish everyone good luck. 20+yrs on ADs.`09 went on citalopram`18 went on sertraline`23 went on escitalopramAug `26 now changed to sertraline (again).Was on 10mg escitalopram now on 125mg sertraline
October 2Oct 2 14 hours ago, Wilf said:Dear Sarah, Thanks for asking about my welfare. At the end of July I started changing from 10mg escitalopram/day to sertraline. For 2 wks I was given 50mg sert every day and 10mg esc every other day. Then 50mg sert only. I was impatient and raised it to 75, then 100 over 2 wks, and then after 3 wks more I raised it to 125 . I did this in the belief that I could increase at a much faster pace than reducing. I have been on 125 for a month now and starting to improve. The tension headaches have reduced although my head is still ringing.This is definitely a much faster switch than we would generally advise, but I'm glad your symptoms have been pretty manageable and are starting to improve. 14 hours ago, Wilf said:I read that there is no cure for a damaged autonomic , but I would love to understand how and why ------ it might be useful in coping. At every turn I have been denied psychiatric referral which might have been good in coping.If by no cure you mean no magic pill or medical treatment that can fix us, yes you're right. But the collective experience of the community over many years shows that the nervous system does recover from these injuries over time -- though sometimes it needs a very long time.14 hours ago, Wilf said:I am lucky in that my case is relatively minor compared to some I have seen on here. I would like to see GPs read some of the testimonies on here --- it would open their eyes.We certainly all wish that doctors, and the medical community more broadly, would take these issues much more seriously! I hope your symptoms continue to progress in a positive direction. I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. Current regimen:Cymbalta - 90 mg/daySeroquel - 12.5 mg/day*holding to stabilize as of Apr 2026 History:Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to presentCymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper offZoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present
October 2Oct 2 Author Thank you again. One thing that really stands out is to go slowly and avoid changing regimes. 20+yrs on ADs.`09 went on citalopram`18 went on sertraline`23 went on escitalopramAug `26 now changed to sertraline (again).Was on 10mg escitalopram now on 125mg sertraline
October 3Oct 3 17 hours ago, Wilf said:Thank you again. One thing that really stands out is to go slowly and avoid changing regimes.Yes, absolutely. Any change needs to happen much more slowly than your doctor will tell you. I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. Current regimen:Cymbalta - 90 mg/daySeroquel - 12.5 mg/day*holding to stabilize as of Apr 2026 History:Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to presentCymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper offZoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present
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