Skip to content
View in the app

A better way to browse. Learn more.
The Antidepressant Harm and Recovery Forum

A full-screen app on your home screen with push notifications, badges and more.

To install this app on iOS and iPadOS
  1. Tap the Share icon in Safari
  2. Scroll the menu and tap Add to Home Screen.
  3. Tap Add in the top-right corner.
To install this app on Android
  1. Tap the 3-dot menu (⋮) in the top-right corner of the browser.
  2. Tap Add to Home screen or Install app.
  3. Confirm by tapping Install.

Go2zero: Tapering Wellbutrin after succesful stopping SSRI's

Go2zero
Go2zero
in Introductions & Ongoing Recoveries

Featured Replies

11 hours ago, Go2zero said:

I do hope so. Last night was night 4 four after changing to the new batch. First night without vivid dreams! Other symptoms are still there, but I see the dream thing as a positive sign.

How do you see them as a positive sign?

  • Current medications: Fluoxetine 4 mg, Wellbutrin IR 150 mg, Tirosint 88 Mcg, Metformin 1500 mg (500 in the morning/noon, 1000 at night)

 

01 Jan 2025 Prozac 40mg; Wellbutrin XL 450mg
01 Feb 2025 Prozac 30mg (-25%); Wellbutrin XL 450mg
01 Mar 2025 Prozac 20mg(-33%); Wellbutrin XL 450mg
01 Apr 2025 Prozac 20mg; Wellbutrin XL 300mg (-33%)
01 May 2025 Prozac 20mg; Wellbutrin XL 150mg (-50%)
15 Jun 2025 Prozac 10mg(-50%); Wellbutrin XL 150mg

 

01 Aug 2025 Prozac 10mg every other day; Wellbutrin ~75mg (splitting XL 150mg)

 

22 Aug 2025 Panic attack and intrusive thoughts → took Xanax 0.25mg once; psychiatrist advised reinstating Prozac 10mg daily and Wellbutrin XL 150mg. Within a few days I felt somewhat better.

 

Between 22 Aug 2025 and 14 Nov 2025: a handful of times (exact dates unclear) during panic episodes, I took an extra Prozac 20mg and Xanax 0.25mg. Last Xanax dose: 1/4 of 0.25mg tablet on 10 Jan 2026.

 

I was also taking supplements and Ozempic (last dose: 06 Nov 2025), which I believe contributed to my destabilization despite previously tolerating them. I had not yet found the withdrawal communities and continued to experience panic and intrusive thoughts, so my psychiatrist advised dose increases:

 

01 Oct 2025 Wellbutrin XL 300mg (+100%) (brief increase; caused palpitations → reduced)
21 Oct 2025 Wellbutrin XL 150mg (-50%)resumed and held
01 Nov 2025 Prozac 15mg (+50%) (brief increase; worsened palpitations/SI → reduced)
14 Nov 2025 Prozac 10mg (-33%)resumed and held

 

Since 21 Oct 2025: holding Wellbutrin XL 150mg
Since 14 Nov 2025: holding Prozac 10mg

 

After this point, I focused on eliminating other medications and supplements, which is also when I found the withdrawal communities.

Prozac (2026)

  • 4/1/26: 10 → 9.75 mg (-2.5%)

  • 4/7: 9.75 → 9.5 mg (-2.6%)

  • ~4/23: 9.5 → 9 mg (-5.3%)

  • 5/2: 9 → 8.2 mg (-8.9%)

  • 5/10: 8.2 → 6.8 mg (-17.1%)

  • 5/21: 6.8 → 5.8 mg (-14.7%)

  • 6/4: 5.8 → 5 mg (-13.8%)

  • 6/28: 5 → 4.3 mg (-14%)

  • 7/22: 4.3 → 4 mg (-7%)

  • 8/4: switched to commercial liquid, same 4 mg dose

    HOLD

Wellbutrin (2026)

  • 6/15/26: XL 150 mg → IR 75 mg BID (150 mg/day; formulation change only)

  • 7/13–7/14: ~132 mg/day briefly

  • 7/15: returned to 150 mg/day

  • 8/13: 150 → 75 mg/day (-50%)

  • 8/13-8/15: 75 mg/day

  • 8/16: returned to 150 mg/day

  • Current: Wellbutrin IR 150 mg daily

    HOLD

 

  • Recent drugs and supplements taken in the last 12 months are: Fluoxetine 10 mg, Wellbutrin XL 150 mg, Tirosint 112 Mcg, Cytomel 15 mg, Zepbound 2.5 (last and only dose was 10/1/25), Ozempic (last dose was 11/6, stopped bc made intrusive thoughts way worst), xanax 0.25 (only used total of 6 in my life, occasionally when panic was at its worst; last dose 1/4 tablet of 0.25 mg on 1/10/2026), Omega 3, Vitamin D, Magnesium citrate, Vitamin C, naltrexone, pyloguard, probiotic, GI synergy, pancreatic enzymes, iron, L-threanine, testosterone cream, Hunger powder, Calocurb, Ovasitol, magnesium glycinate, berberine, chromium,

    Keflex, ibuprofen, gol gav zaban, senna, magnesium L-threonate, Mag07, Sutab, lipotropic injection, Progesterone, Paxlovid 

  • A history of drugs taken 24 months ago and beyond: - Fluoxetine 40 mg (2003-2009), Fluoxetine 80 mg (2009-2019), Fluoxetine 40 mg (2019-2025), Wellbutrin XL 450 (2013-2025), Synthroid 88 Mcg (2005-2010), Synthroid 112 (2011-2025), Cytomel 25 (2019-2025)

  • Author
7 minutes ago, Healthyagain said:

How do you see them as a positive sign?

No vivid dreams last night may be a sign that symptoms are getting less. Not 100% sure yet. But I prefer to focus on the possible positives.

And I know that will pass...

1993    Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006      No medication

2006   Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro 

Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin

2016  Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg

November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems.

April 2017 – March 2019       Lexapro 0,6 mg        April 2017 - August 2018       Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step.

March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..)    

Wellbutrin down from 37,5mg to 35,3mg 

October 2019        Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks       Prozac up dosage to 1,2 mg

March 2020     Wellbutrin in 2 steps down from 35,3mg to 33,3mg   Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin  until total off Prozac. 

February 2020 – November 2020   Prozac down in steps from 1,2mg to 0,57mg. 

Jan 2021 :  Prozac down to:  0,55> 0,53>0,51mg,   Feb 0,47mg ,  Mar 0,42mg,   Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg  Long hold of 172 days until March 2022

January 20, 2022:  Wellbutrin from 33,3 to 32,4mg

March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14  Jan 2023 0,13, 0,12, 0,11  Feb 0,10, 0,09 Mar 0,08 ,  June 0,07 , July 0,06,  0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009   Jan 2024 0,008, 0,007,  0,006,  0,005, 0,004, 0,003, 0,002, 0,001, Feb  0,0007.  0,0005,   0,0003, 0,0001,  

Feb 23, 2024:  0,00000

 

Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0         Jan 2025 19,6 mg,  Mar 18,8, Oct 18,68 , 18,55, 18,43, Dec 18,30, Jan 2026 17,93 , Mar 17,7

 

Here is my thread (and tapering history) https://www.survivingantidepressants.org/forums/topic/23288-go2zero-getting-off-wellbutrin-and-prozac/

    •
    • Like 3
    23 minutes ago, Go2zero said:

    And I know that will pass...

    Absolutely. You will get better.

    2011-2015 - tapered off 300mg of Venlafaxine after 6 years of use

    2005-2021 - 450 mg Bupropion daily

    2021-2023 - tapered Bupropion to zero 

     

    • Like 4
    10 hours ago, j1290 said:

    Absolutely. You will get better.

    100% :)

    I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

     

    If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

    Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

    For US members details here.

    •
    • Like 4

    Create an account or sign in to comment
    Go to topic listing

    Account

    Navigation

    Search

    Search

    Configure browser push notifications
    Chrome (Android)
    1. Tap the lock icon next to the address bar.
    2. Tap Permissions → Notifications.
    3. Adjust your preference.
    Chrome (Desktop)
    1. Click the padlock icon in the address bar.
    2. Select Site settings.
    3. Find Notifications and adjust your preference.