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freerunnerrr: Actuall Hell

Featured Replies

This group, a previous forum that ran for 15 years (survivingantidepressants), and in general most prescribed harm support groups do not recommend sporadic benzo and beta blocker use. Are you taking benzos regularly at a consistent dose, or ad hoc? If you're taking a consistent dose, this may need to be tapered- don't just stop. If you're taking them randomly on and off, we'd recommend not continuing to do so, but it would be good to discuss this in more detail.

As for the antidepressants- when you say you've been having symptoms when you make cuts, what tapering schedule/plan have you been following? It looks like a lot of changes have been made in the last year or so, I wouldn't be surprised if this significantly contributing to symptoms and causing instability.

 

You are very welcome here and I hope you find the site supportive.

Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all.

 

Perhaps you should consider this post an artistic work of fiction written for entertainment purposes.


Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants

 

15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects)

Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise

1 month taper  to 0mg

Last dose April 2023

Severe withdrawal syndrome with many physical symptoms

Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.

  • Luke changed the title to freerunnerrr: 10 years on antidepressants and every small taper feels like my nervous system is short-circuiting

I relate to a good portion of this despite my med history being relatively short. But all in all everyone’s experience is going to be different and alike in some regards. My best advice is learning to lay low, keep chore/busyness expectations down, literally baby yourself gently as long as possible because the nervous system is hella fragile, avoid triggers like overstimulation, kinda relearn life till things even out again. I’m about 7 months out from lexapro and found it a BIG detour from the original problem. Look up waves and windows, it’s very accurate.

Started 5mg lexapro 10/10/25 for anxiety. Initially helped but had adverse neurological affects in my bladder. Had to stop after two weeks and tapered over a month. From December to currently I’ve been withdrawing since with waves and windows. About 60% better, thank God. Currently using Xanax prn. I will not touch another ssri and will be seeking God and healthy lifestyles.


No weapon formed against me shall prosper” Isaiah 54:17

“For we wrestle not against flesh and blood, but against principalities, against powers, against the rulers of the darkness of this world, against spiritual wickedness in high places.“ Ephesians 6:12

”Bringing every thought into captivity to the obedience of Christ.” 2 Cor 10:5

”Do not grieve, for the joy of the Lord is your strength.” Neh 8:10

13 hours ago, freerunnerrr said:

I’ve been on psychiatric meds for around 10 years and have tried escitalopram, fluvoxamine, venlafaxine, sertraline, vortioxetine and others. I was on sertraline up to 100 mg and tapered off slowly. Vortioxetine was used as a buffer around 4 mg, and now I’m around 3 mg after reducing from 4 mg.


Every reduction seems to trigger delayed symptoms, usually worse around day 8–14: intense inner agitation/akathisia-like restlessness, brain fog, derealization/depersonalization, vivid dreams, morning intrusive thoughts, burning/tingling sensations, numbness-like feelings in limbs, muscle twitches/fasciculations, nausea, OCD-like fear loops and chest/sternum tightness.


One of the strangest symptoms is a racing heartbeat that stays around 90–100 bpm at rest and does not easily come down, even when I don’t feel anxious. It appears randomly during tapers, often fades after 3–4 weeks after a reduction, but feels almost chronic when I reduce every 3 weeks. Benzos don’t really stop it, and it usually settles at night if I don’t take a beta blocker. I’ve been checked many times by cardiologists, but I still fear “this time is different” and that it could be heart-related.


I also get badly overstimulated from longer stimulation like PvP games, doomscrolling, arguments or too much screen time. During it I feel this internal pressure/urgency, like my nervous system is rushing to finish something under a deadline. After I stop, I feel derealized, foggy, tense and mentally awful, like my system overheated and can’t calm down.


I’m very sensitive to medication changes and small reductions feel huge to me. I’m not asking for a diagnosis, just wondering if others had similar withdrawal/adaptation symptoms from tapering SSRIs/vortioxetine after long-term use and how long it took to stabilize.

As you already have a thread on here I have merged this with your existing thread, please keep all your posts about your journey here in your intro thread.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • 3 weeks later...
  • Author

Is Trintellix/brintellix homogenous and does dry cut down taper method works if scaled with pharma scale?

"VERY BAD METABOLISER OF SEROTONERGETIC MEDS AND VERY SENSITIVE NS" I HAVE PHARMACOGENETIC TEST

WAS diagnoaed with anxiety and mild Ocd

2016 first time ad escitalopram 10 mg+ 10 mg aripiprazole-First hell

2018-fluvoxamine 100 mg with 100 mg tiapride

Like 2-3 years

Then tried every possible ssri snr and tca

2025- Sertraline 100 mg

After 2 months - Brintellix 10 mg - slowly started tapering down, didnt know that was from withdraw and got prescribed new drug "deanxit"

Then renewed brintellix at 5 mg

Then started titrating down again to 2.5- FELT AMAZING

ABRUPTLY STOPPED- Got put on fluvoxamine 25mg beacuse of my pharmacogenetic test that i made for 3k

Got withdraw and activation at once and stopped. Got put on mirtazepine couldnt even live and exist at this point

Then put on Sertraline 100 mg

Then i got things in my hands

Down titrated to these days at 12.5 mg sertraline+ 4 mg of Brintellix

I have to get rid of Sertraline, but couldnt stand it so i added something i could!

Im on 1.5 clonazepam too to help reduce symptoms

I dont have the exact dates and times but ive been on many meds for 1-3 weeks, have many tried again and again at different doses

14 hours ago, freerunnerrr said:

Is Trintellix/brintellix homogenous and does dry cut down taper method works if scaled with pharma scale?

The tablets are generally not mixed on a perfect microscopic level, but they should be mixed enough to a level that dry cutting works as a method of tapering.

Also i merged your new topic to your existing thread, please do not open new threads and just ask questions on your introduction thread, thank you 🙏.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.

Current Medications: Mirtazapine, Lasea (lavender oil) before bed.

------------------------------------------

Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mg

Note: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.

  • Author
6 hours ago, Lighty said:

The tablets are generally not mixed on a perfect microscopic level, but they should be mixed enough to a level that dry cutting works as a method of tapering.

Also i merged your new topic to your existing thread, please do not open new threads and just ask questions on your introduction thread, thank you 🙏.

I mean, im asking because i can cut perfectly and scalw miligrams like lets say 75 mg of tablet waight to be equal to ~2.5mg of active subatance. My worry is that if i take it like that one day i can consume 2.5 mg other day 1 mg, other day 5 mgs, other 3.5 if its not homogenous mix, or it will be more like 0.1-0.5 difference and not that big fluctuation. I ask because no psychiatrist or pharma have the answer tho this.....

"VERY BAD METABOLISER OF SEROTONERGETIC MEDS AND VERY SENSITIVE NS" I HAVE PHARMACOGENETIC TEST

WAS diagnoaed with anxiety and mild Ocd

2016 first time ad escitalopram 10 mg+ 10 mg aripiprazole-First hell

2018-fluvoxamine 100 mg with 100 mg tiapride

Like 2-3 years

Then tried every possible ssri snr and tca

2025- Sertraline 100 mg

After 2 months - Brintellix 10 mg - slowly started tapering down, didnt know that was from withdraw and got prescribed new drug "deanxit"

Then renewed brintellix at 5 mg

Then started titrating down again to 2.5- FELT AMAZING

ABRUPTLY STOPPED- Got put on fluvoxamine 25mg beacuse of my pharmacogenetic test that i made for 3k

Got withdraw and activation at once and stopped. Got put on mirtazepine couldnt even live and exist at this point

Then put on Sertraline 100 mg

Then i got things in my hands

Down titrated to these days at 12.5 mg sertraline+ 4 mg of Brintellix

I have to get rid of Sertraline, but couldnt stand it so i added something i could!

Im on 1.5 clonazepam too to help reduce symptoms

I dont have the exact dates and times but ive been on many meds for 1-3 weeks, have many tried again and again at different doses

Just now, freerunnerrr said:

I mean, im asking because i can cut perfectly and scalw miligrams like lets say 75 mg of tablet waight to be equal to ~2.5mg of active subatance. My worry is that if i take it like that one day i can consume 2.5 mg other day 1 mg, other day 5 mgs, other 3.5 if its not homogenous mix, or it will be more like 0.1-0.5 difference and not that big fluctuation. I ask because no psychiatrist or pharma have the answer tho this.....

I wouldn't worry about it too much, either way no tapering method or compounding is 100% accurate, dry cutting is accurate enough and tends to get more non accurate on the smallest tablet weights, but again it should be okay overall. I am telling from experience, I don't think you should worry too much. maybe if you want, on the lowest doses you can move to liquid tapering.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.

Current Medications: Mirtazapine, Lasea (lavender oil) before bed.

------------------------------------------

Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mg

Note: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.

On 6/18/2026 at 8:01 PM, freerunnerrr said:

One of the strangest symptoms is a racing heartbeat that stays around 90–100 bpm at rest and does not easily come down

Hey man , I’ve had this for months!

Spiro

Current Medications (April 2026)

* Zoloft 125mg (a.m.)

* Seroquel 75mg (night)

* Clonazepam 0.5mg (a.m.)

Drug History

January 2013 Zoloft 100mg

~2021 Xanax 0.5mg PRN (once every 2 weeks)

July 2025 Zoloft 0mg

October 2025 Lithium 150mg

October 2025 Gabapentin 600mg

October 2025 Seroquel 200mg

December 2025 Seroquel 25mg

January 2026 Lithium 0mg

January 2026 Zoloft 100mg

January 2026 Zyprexa single dose

January 2026 Geodon injection

January 2026 Lamotrigine 100mg

January 2026 Seroquel 200mg

March 2026 Lamotrigine 0mg

March 2026 Seroquel 75mg

March 2026 Gabapentin 0mg

March 2026 Clonazepam 0.5mg twice daily

April 2026 Clonazepam 0.5mg

April 2026 Zoloft 125mg

April 2026 Seroquel 75mg

Taper / Change Details

* July 2025: Tapered Zoloft from 100mg → 0mg over ~4 weeks:

* Week 1: 50mg

* Week 2: 25mg

* Week 3: 12.5mg

* Week 4: 0mg

* December 2025: Tapered Seroquel from 200mg → 25mg over a few weeks (rapid taper)

* January 2026: Lithium stopped (150mg → 0mg)

* March 2026: Lamotrigine stopped (100mg → 0mg)

* March–April 2026:

* Tapered Seroquel from 200mg → 75mg over ~5 weeks

* Tapered Gabapentin from 600mg → 0mg over ~5 weeks

* Clonazepam: Started at 0.5mg twice daily → now 0.5mg morning only

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