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Mittenraised: Seroquel tapering from 250 MG

Mittenraised
Mittenraised
in Introductions & Ongoing Recoveries

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  • Author

I can honestly say, it takes a full 10 days to feel "normal" after tapering. 3 to 4 rough days with very little sleep or recovery, 6 so-so nights of broken sleep then it's right back to regular business.

The human body is an amazing machine when you let it do its thing.

~M

Seroquel taper- Dropped 10% to 225 mg-2/3/23, 200mg XR 2/19/23, 180 XRmg 3/20/23, 162 XRmg 4/25/23, 150 XR 5/25/23, 7/31/23 137.5mg XR & IR, 9/4/23 125mg (100mg XR,25mg IR)  9/21/23, (100mg XR, 12.5mg IR) 10/28/23, (100mg XR) 11/19/23, (50mg XR, 50mg IR) 12/8/23, (50mg XR, 42mg IR) 1/1/24, 82.8mg 2/7/24, 75mg 2/22/24, 67.5mg 3/22/24, 61mg 5/6/24, 54.9mg 5/31/24, 50mg 6/15/24, 45mg 7/16/24, 40.5mg 8/16/24, 36mg 9/16/24, 31.5mg 10/22/24, 28mg 12/4/2024, 25mg 12/25/24, 22.5mg 1/24/25, 20mg 2/14/24, 18mg 3/7/25, 16.2mg, 4/3/25, 14.6mg 5/2/25, 12 mg, 6/1/25, 10.5 mg, 6/28/25, 9.45 mg, 7/16/25, 8.5 mg, 8/6/25, 7.65mg, 8/20/25, 6.9 mg 9/11/25, 6.2 mg 9/27/25, 5.6 mg 10/13/25, 5.0 mg 11/2/25, 4.5 mg 11/23/25, 4.0 mg 12/14/25, 3.6 mg 1/10/26, 3.25 mg 2/27/26, 2.9 mg 3/26/26, 2.6 mg 4/21/26, 2.25 mg 6/1/26, 2.0 mg 6/30/26, 1.8 MG 7/31/26, 1.62 MG 8/31/26

Supplements- Magnesium Glycinate 420mg, 1000mg fish oil twice daily, Niacinamide 500mg- 3 daily, L-Theanine 200mg- 2 daily.

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    • Chippy
      Chippy

      I think being in touch with yourself is the key to a good taper. Listening to the nuance of your body telling what to do. 👍

    • Mittenraised
      Mittenraised

      2.0 mg tonight. Hopefully, as good as last month.

    • Bernadette
      Bernadette

      Mittenraise, welcome to the forum, It's good to see that your in tune with what your system is telling you. I vaguely remember when I hit 3mg of Citalopram my system did not handle any caffeine, an

    22 minutes ago, Mittenraised said:

    I can honestly say, it takes a full 10 days to feel "normal" after tapering. 3 to 4 rough days with very little sleep or recovery, 6 so-so nights of broken sleep then it's right back to regular business.

    The human body is an amazing machine when you let it do its thing.

    Glad to hear things are still going pretty smoothly for you. I hope to be in your shoes sometime soon!

    I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. 

    Current regimen:

    Cymbalta - 90 mg/day

    Seroquel - 12.5 mg/day

    *holding to stabilize as of Apr 2026

     

    History:

    Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

    Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

    Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

    Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

    Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

    Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

    Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

     

    • Author
    On 7/12/2026 at 5:58 PM, SarahMc said:

    Glad to hear things are still going pretty smoothly for you. I hope to be in your shoes sometime soon!

    Thanks @SarahMc ! You will get there too.

    Seroquel taper- Dropped 10% to 225 mg-2/3/23, 200mg XR 2/19/23, 180 XRmg 3/20/23, 162 XRmg 4/25/23, 150 XR 5/25/23, 7/31/23 137.5mg XR & IR, 9/4/23 125mg (100mg XR,25mg IR)  9/21/23, (100mg XR, 12.5mg IR) 10/28/23, (100mg XR) 11/19/23, (50mg XR, 50mg IR) 12/8/23, (50mg XR, 42mg IR) 1/1/24, 82.8mg 2/7/24, 75mg 2/22/24, 67.5mg 3/22/24, 61mg 5/6/24, 54.9mg 5/31/24, 50mg 6/15/24, 45mg 7/16/24, 40.5mg 8/16/24, 36mg 9/16/24, 31.5mg 10/22/24, 28mg 12/4/2024, 25mg 12/25/24, 22.5mg 1/24/25, 20mg 2/14/24, 18mg 3/7/25, 16.2mg, 4/3/25, 14.6mg 5/2/25, 12 mg, 6/1/25, 10.5 mg, 6/28/25, 9.45 mg, 7/16/25, 8.5 mg, 8/6/25, 7.65mg, 8/20/25, 6.9 mg 9/11/25, 6.2 mg 9/27/25, 5.6 mg 10/13/25, 5.0 mg 11/2/25, 4.5 mg 11/23/25, 4.0 mg 12/14/25, 3.6 mg 1/10/26, 3.25 mg 2/27/26, 2.9 mg 3/26/26, 2.6 mg 4/21/26, 2.25 mg 6/1/26, 2.0 mg 6/30/26, 1.8 MG 7/31/26, 1.62 MG 8/31/26

    Supplements- Magnesium Glycinate 420mg, 1000mg fish oil twice daily, Niacinamide 500mg- 3 daily, L-Theanine 200mg- 2 daily.

    • 2 weeks later...
    • Author

    6 days out from my drop it 1.8 MG. I had a few high stress days; work and home life. It really effects the sleep patterns.

    I've recovered but rest, sleep and recovery are a top priority.

    Seroquel taper- Dropped 10% to 225 mg-2/3/23, 200mg XR 2/19/23, 180 XRmg 3/20/23, 162 XRmg 4/25/23, 150 XR 5/25/23, 7/31/23 137.5mg XR & IR, 9/4/23 125mg (100mg XR,25mg IR)  9/21/23, (100mg XR, 12.5mg IR) 10/28/23, (100mg XR) 11/19/23, (50mg XR, 50mg IR) 12/8/23, (50mg XR, 42mg IR) 1/1/24, 82.8mg 2/7/24, 75mg 2/22/24, 67.5mg 3/22/24, 61mg 5/6/24, 54.9mg 5/31/24, 50mg 6/15/24, 45mg 7/16/24, 40.5mg 8/16/24, 36mg 9/16/24, 31.5mg 10/22/24, 28mg 12/4/2024, 25mg 12/25/24, 22.5mg 1/24/25, 20mg 2/14/24, 18mg 3/7/25, 16.2mg, 4/3/25, 14.6mg 5/2/25, 12 mg, 6/1/25, 10.5 mg, 6/28/25, 9.45 mg, 7/16/25, 8.5 mg, 8/6/25, 7.65mg, 8/20/25, 6.9 mg 9/11/25, 6.2 mg 9/27/25, 5.6 mg 10/13/25, 5.0 mg 11/2/25, 4.5 mg 11/23/25, 4.0 mg 12/14/25, 3.6 mg 1/10/26, 3.25 mg 2/27/26, 2.9 mg 3/26/26, 2.6 mg 4/21/26, 2.25 mg 6/1/26, 2.0 mg 6/30/26, 1.8 MG 7/31/26, 1.62 MG 8/31/26

    Supplements- Magnesium Glycinate 420mg, 1000mg fish oil twice daily, Niacinamide 500mg- 3 daily, L-Theanine 200mg- 2 daily.

    • Author

    1.8 MG tonight... getting closer!

    Seroquel taper- Dropped 10% to 225 mg-2/3/23, 200mg XR 2/19/23, 180 XRmg 3/20/23, 162 XRmg 4/25/23, 150 XR 5/25/23, 7/31/23 137.5mg XR & IR, 9/4/23 125mg (100mg XR,25mg IR)  9/21/23, (100mg XR, 12.5mg IR) 10/28/23, (100mg XR) 11/19/23, (50mg XR, 50mg IR) 12/8/23, (50mg XR, 42mg IR) 1/1/24, 82.8mg 2/7/24, 75mg 2/22/24, 67.5mg 3/22/24, 61mg 5/6/24, 54.9mg 5/31/24, 50mg 6/15/24, 45mg 7/16/24, 40.5mg 8/16/24, 36mg 9/16/24, 31.5mg 10/22/24, 28mg 12/4/2024, 25mg 12/25/24, 22.5mg 1/24/25, 20mg 2/14/24, 18mg 3/7/25, 16.2mg, 4/3/25, 14.6mg 5/2/25, 12 mg, 6/1/25, 10.5 mg, 6/28/25, 9.45 mg, 7/16/25, 8.5 mg, 8/6/25, 7.65mg, 8/20/25, 6.9 mg 9/11/25, 6.2 mg 9/27/25, 5.6 mg 10/13/25, 5.0 mg 11/2/25, 4.5 mg 11/23/25, 4.0 mg 12/14/25, 3.6 mg 1/10/26, 3.25 mg 2/27/26, 2.9 mg 3/26/26, 2.6 mg 4/21/26, 2.25 mg 6/1/26, 2.0 mg 6/30/26, 1.8 MG 7/31/26, 1.62 MG 8/31/26

    Supplements- Magnesium Glycinate 420mg, 1000mg fish oil twice daily, Niacinamide 500mg- 3 daily, L-Theanine 200mg- 2 daily.

    •
    • Like 1

    👍

    1998 -1999 Paxil CT after 5 months.

    1999 - 2024 every 2 to 4 years went from one SSRI to the next. That includes Luvox, Zoloft, Cymbalta, Celexa, Prozac, Lexapro.

    2000-2024 lorazepam 2mg.

    April 2024 one dose of Effexor, July 2024 one dose of Paxil, July 2024 two weeks of Mirtazapine. September 2024 Lexapro 10mg, Depakote 250mg, Vistaril 25 mg ,Proppranolol 10mg, Requip 2mg Trazadone 50mg. March 2025 off Depakote,Propranolol,vistaril,Trazadon.

    March 2025 Zyprexa added at 2.5 mg.”for sleep and anxiety”. Went up to 7.5mg in June.

    September 2025 started tapering Zyprexa and Requip.

    February 2026 off of Zyprexa and Requip. Reduced Lexapro to 5mg

    7/4/2026-4.5mg

    8/1/2026-4.0mg

    •
    • Like 1
    • 2 weeks later...
    • Author

    A few light sleep nights. Nothing significant. Caffeine late is still an issue, even chocolate ice cream.

    Seroquel taper- Dropped 10% to 225 mg-2/3/23, 200mg XR 2/19/23, 180 XRmg 3/20/23, 162 XRmg 4/25/23, 150 XR 5/25/23, 7/31/23 137.5mg XR & IR, 9/4/23 125mg (100mg XR,25mg IR)  9/21/23, (100mg XR, 12.5mg IR) 10/28/23, (100mg XR) 11/19/23, (50mg XR, 50mg IR) 12/8/23, (50mg XR, 42mg IR) 1/1/24, 82.8mg 2/7/24, 75mg 2/22/24, 67.5mg 3/22/24, 61mg 5/6/24, 54.9mg 5/31/24, 50mg 6/15/24, 45mg 7/16/24, 40.5mg 8/16/24, 36mg 9/16/24, 31.5mg 10/22/24, 28mg 12/4/2024, 25mg 12/25/24, 22.5mg 1/24/25, 20mg 2/14/24, 18mg 3/7/25, 16.2mg, 4/3/25, 14.6mg 5/2/25, 12 mg, 6/1/25, 10.5 mg, 6/28/25, 9.45 mg, 7/16/25, 8.5 mg, 8/6/25, 7.65mg, 8/20/25, 6.9 mg 9/11/25, 6.2 mg 9/27/25, 5.6 mg 10/13/25, 5.0 mg 11/2/25, 4.5 mg 11/23/25, 4.0 mg 12/14/25, 3.6 mg 1/10/26, 3.25 mg 2/27/26, 2.9 mg 3/26/26, 2.6 mg 4/21/26, 2.25 mg 6/1/26, 2.0 mg 6/30/26, 1.8 MG 7/31/26, 1.62 MG 8/31/26

    Supplements- Magnesium Glycinate 420mg, 1000mg fish oil twice daily, Niacinamide 500mg- 3 daily, L-Theanine 200mg- 2 daily.

    •
    • Like 1
    4 hours ago, Mittenraised said:

    A few light sleep nights. Nothing significant. Caffeine late is still an issue, even chocolate ice cream.

    Glad things are not too bad. Yes I think keeping the caffeine to a min and only earlier in the day is a good move. I noticed dark chocolate made my sleep worse at one point.

    I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

     

    If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

    Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

    For US members details here.

    •
    • Like 1
    • 3 weeks later...
    • Author

    1.62 MG tonight!

    Seroquel taper- Dropped 10% to 225 mg-2/3/23, 200mg XR 2/19/23, 180 XRmg 3/20/23, 162 XRmg 4/25/23, 150 XR 5/25/23, 7/31/23 137.5mg XR & IR, 9/4/23 125mg (100mg XR,25mg IR)  9/21/23, (100mg XR, 12.5mg IR) 10/28/23, (100mg XR) 11/19/23, (50mg XR, 50mg IR) 12/8/23, (50mg XR, 42mg IR) 1/1/24, 82.8mg 2/7/24, 75mg 2/22/24, 67.5mg 3/22/24, 61mg 5/6/24, 54.9mg 5/31/24, 50mg 6/15/24, 45mg 7/16/24, 40.5mg 8/16/24, 36mg 9/16/24, 31.5mg 10/22/24, 28mg 12/4/2024, 25mg 12/25/24, 22.5mg 1/24/25, 20mg 2/14/24, 18mg 3/7/25, 16.2mg, 4/3/25, 14.6mg 5/2/25, 12 mg, 6/1/25, 10.5 mg, 6/28/25, 9.45 mg, 7/16/25, 8.5 mg, 8/6/25, 7.65mg, 8/20/25, 6.9 mg 9/11/25, 6.2 mg 9/27/25, 5.6 mg 10/13/25, 5.0 mg 11/2/25, 4.5 mg 11/23/25, 4.0 mg 12/14/25, 3.6 mg 1/10/26, 3.25 mg 2/27/26, 2.9 mg 3/26/26, 2.6 mg 4/21/26, 2.25 mg 6/1/26, 2.0 mg 6/30/26, 1.8 MG 7/31/26, 1.62 MG 8/31/26

    Supplements- Magnesium Glycinate 420mg, 1000mg fish oil twice daily, Niacinamide 500mg- 3 daily, L-Theanine 200mg- 2 daily.

    •
    • Like 2

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