Catbird: Dealing with Polypharmacy

September 13Sep 13

Author

1 hour ago, RachelSusan said:
@Catbird Oh Catbird, I'm so sorry. After having several weeks that were relatively quiet, I can imagine how unsettling it must be to have all of this come crashing back while you're away from home.
And what happened with your brother must be incredibly painful. I have both a brother and sister, and I can't even imagine how painful this must be.
I hope things settle down again soon and that you're able to get some relief and salvage something from the rest of your trip.

Thanks @RachelSusan. Lots of SVT episodes too.

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day)

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

September 13Sep 13

@Catbird I hope you're able to get some relief soon.

I am not a health professional in any way, and I do not give medical advice. These are only my opinions. Any decisions about your medical care should be discussed with a qualified medical professional.

Quote of the century: "it's much easier to stop humpty from falling then it is to put him back together again." * as relayed to us by Chippy paraphrasing a comment by Altostrata, the founder of Surviving Antidepressants

If you would like to reach me, please post on my thread and tag @rachelsusan, or post on your thread and tag in the same way, so I will see it. 😀😀😀

Gabapentin reduction. 2026 Transitioned to partial liquid, 100mg in liquid and a 100mg capsule for a total of a 200mg dose. Dose three times a day. April 18 2026 first cut to 195mg (2.5%). May 18, 2026 to 187.5 (3.85%), June 28, 2026 to 185 (1.33%), July 28 to 180 mg (2.7%), Sept. 2, 2026 to 175mg (2.78%),

HISTORY FOR ZOLOFT TAPER

Feb. 2016 to June 2016 - Was on 150mg Zoloft.

Quit Zoloft (Sertraline) June 2016, reinstated 50mg of Zoloft July 2016. From July 2016 to October 2016 went from 50 mg down 2.3 mg. I up-dosed in November 2016 to 12.5 mg. Held there until January 2017 when I started a much slower taper.

STARTING SENSIBLE ZOLOFT TAPERING USING GUIDELINES FROM ANOTHER SITE - WHICH WAS VERY HELPFUL

Dec. 10, 2016 – Switched to liquid Zoloft (sertraline) at 12.5 mg. Held until Jan. 2017, then resumed a slow taper. I tapered continuously from that point onward; however, my detailed taper records begin with Jan. 4, 2020. - Jan. 4, 2020 1.875 mg (6.3%). Jan. 25, 2020 1.75 mg. Feb. 29, 2020 1.625mg (7.10%). Apr. 4, 2020 1.5 mg. May 9, 2020 1.375 mg. June 6, 2020 1.25 mg. (9.10%). July 4, 2020 1.125 mg. (10%). August 15, 2020 1.0 mg. Oct 24, 2020 .875 mg. Nov. 28, 2020 .75mg. Jan 16, 2021 .685mg (8.7%). Feb 13, 2021 .62mg. March 12, 2021 .56mg. May 1, 2021 .375mg. May 29, 2021 .25mg. June 26, 2021 .125mg. July 25, 2021 .065mg. August 22, 2021 .048mg. October 2, 2021 .043mg. October 10, 2021 .038mg. October 23, 2021 .035mg. October 30, 2021 .032mg. Nov. 13, 2021 .030 mg. Dec 4, 2021 .0285 mg. Dec 11, 2021 .0265 mg. Dec 18, 2021 .0246 mg. Dec 25, 2021 .023mg. Jan 1, 2022. 0 mg. OFF COMPLETELY

My thread at SA - https://www.survivingantidepressants.org/forums/topic/12649-☼-rachelsusan-zoloft-on-off-and-reinstated/page/28/

September 13Sep 13

So sorry @Catbird ,

This must be so difficult to bear. That would deeply disturb me re family.

I am hoping that once you get back to the safety of your home things will settle with time.

Big hugs of comfort to you xxxxx

Aug 2006 - Sertraline 25/50/75/100mg TO June 2019 - Reduced from 100mg to 50mg over a few months

Sept 2019 - Reduced from 50mg to 25mg lasted a week, then went back up to 50mg, after a few weeks back up to 100mg.

Oct 2021 - Reduced to 75mg, Dec 2021 (mid) reduced to 50mg , March 2022 - Reduced to 25mg

Oct 2022 - Reduce to 0mg (Immediate withdrawal crying, mood unstable, impending doom, digestive probs, tingling,numbness,burning, brain zaps, insomnia)

Feb 2023 - "Panic attack" lasting 14 hours, 2 weeks later start back on 25mg sertraline, 12 hours later severe 'panic attack' with chest pain, tachycardia, restlessness, hyponatraemia, impending doom, racing thoughts, akathisia mild. Taken to emergency.

March 2023 back up to 50mg (on medical advice), April 75mg, May 100mg. Back to 75mg within a few weeks due to feeling too stimulated and anxious.

Nov 2023 resume taper. 70, 65, 60, 55, 50 (March 2024)

April 45mg, May 41mg, June 37mg, July 34mg Aug 31mg, Sept 28mg, Oct 26mg, Nov 25mg, HOLD

Jan 1st 2025 24mg, Jan 12th 23.5mg, Jan 20th 23mg, Feb 20th 22mg, March 20th 21mg, April 14th 18.9mg, May 5th 17mg, May 28th 15.3mg, July 16th 13.7mg, Aug 26th 12.3mg, Sept 16th 10.5 mg, Sept 22, 10mg, Oct 7th 8.3mg, Nov 4th 8mg, Dec 1st 7.7mg, Dec 26th 7mg 2026 Updose to 7.2mg Mar 20th, Back to 7mg Mar 21. Currently holding

Other supplements: Fish oil, Mg citrate/glycinate 150-300mg per day, Ginkgo biloba daily, womens multi vit/min 3 times week, Vitamin C 1000mg night, valerian/passiflora as needed. B12 as needed. Bone support for osteopaenia (Ca/Mg, K, D)

1

September 22Sep 22

Author

I have now had weeks of not sleeping well. I've using insight Timer's Binaural Sleep audio and it does really help me get to sleep. However the quality and duration of sleep has changed. I'm going through the days feeling like a zombie. Has anyone else experienced poorer sleep the lower the dose?

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day)

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

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September 22Sep 22

Hi Catbird, I'm not on a particularly low dose, but my sleep is way, way less than when I was on my regular dose.

I used to be able to sleep anywhere, anytime, all the time.

Now I average about 6 hours. Sometimes less, sometimes a bit more. But it has definitely changed.

And also not a restful sleep.

Hope it changes back again for you soon.

Wombat

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

1

September 22Sep 22

1 hour ago, Catbird said:
I have now had weeks of not sleeping well. I've using insight Timer's Binaural Sleep audio and it does really help me get to sleep. However the quality and duration of sleep has changed. I'm going through the days feeling like a zombie. Has anyone else experienced poorer sleep the lower the dose?

Sending some love @Catbird as a Mirt sufferer I know all about poor sleep and I empathise. xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

1

September 22Sep 22

Dear @Catbird , i’m so sorry that you are struggling with sleep. It makes life so much more difficult.

To your question: I have had phases when I couldn’t sleep and other phases when I slept at least eight hours every night, both on low doses ( from 15 mg to 1 mg I have slept well, the problems started later). For me, it has been the typical withdrawal thing of fluctuation. I hope very much for you that this will only be a short phase! Acceptance is a big thing in not sleeping. The frustration or the strong wish to fall asleep can block the exact thing you want to attain. So practicing acceptance for not sleeping has helped me a lot.

SA Thread: https://www.survivingantidepressants.org/forums/topic/33406-nemina-tapering-escitalopram/

AR Thread: https://antidepressantrecovery.org/topic/14-nemina-tapering-escilatopram-and-zolpidem/

Drug History

2013 - 2025: Zolpidem 5 mg

2015 - Oct 2024: Venlafaxine, Sertralin (Zoloft), Paroxetin (Paxil),duloxtin (cymbalta), Citalopram (Celexa), Escitalopram (Lexapro) and more

Current Drugs

L-Thyroxin 75, Estrogen, Progesteron 200

Tapering Escitalopram

Until Sept 2024: Setralin/zoloft 75 mg

Oct 2024: Switch to Escitalopram / Lexapro 2mg

Then I tapered over a year from 2mg to 0,32 mg (October 2025). 108 days hold without stabilizing. Resumed taper February 2026:

11 Feb 2026 0.314mg

18 Feb 2026 0.307mg

21 Feb 2026 0.302mg

09 Mar 2026 0.297mg

18 April 2026 0,293 mg

18 May 2026 0,285 mg

18 June 2026 0,265 mg

18 July 2026 0,250 mg

18 Aug 2026 0,232 mg

18 Sept 2026 0,232 mg (Holding since 19.8.)

Tapering Zolpidem: From 5 mg to 0,7 mg in 12 months, then just crumbs for several weeks, now 0! (Jan 2026)

Other Supplements

Omega 3, Magnesium Glycinate, Vit D, Calcium, L-theanin, Vit C, Vit K2, Selen

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September 22Sep 22

Author

8 hours ago, Nemina said:
Dear @Catbird , i’m so sorry that you are struggling with sleep. It makes life so much more difficult.
To your question: I have had phases when I couldn’t sleep and other phases when I slept at least eight hours every night, both on low doses ( from 15 mg to 1 mg I have slept well, the problems started later). For me, it has been the typical withdrawal thing of fluctuation. I hope very much for you that this will only be a short phase! Acceptance is a big thing in not sleeping. The frustration or the strong wish to fall asleep can block the exact thing you want to attain. So practicing acceptance for not sleeping has helped me a lot.

Thanks @Nemina wise words. I think the more sedating drugs have been potentiated as my dose of Escitalopram decreases. It’s taken 5+ months for me to stabilise after all the abdominal pain settled. I’ll just have to go with it. Funny thing is I do sleep but the duration is much shorter, leaving me feeling strung out all day.

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day)

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

1

September 22Sep 22

@Catbird I'm sorry the wave has hit again , sometimes your nervous system is so sensitive to anything and maybe the worry of your brother has brought it on. Thinking of you.Xx

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95 18/7 7.5

September 25Sep 25

My sleep has been affected these past months. Like you shorter duration ( waking too early).

I hope you can get some more refreshing sleep at last part of the time.

I have been focusing on accepting the lack of sleep as I lay there. Something I couod never do prior to this.

I haven't found the binnaural sleep audio yet. Doing yoga nidra for sleep still on insight timer.

Wishing you some deep and restorative sleep @Catbird xxxxx

Aug 2006 - Sertraline 25/50/75/100mg TO June 2019 - Reduced from 100mg to 50mg over a few months

Sept 2019 - Reduced from 50mg to 25mg lasted a week, then went back up to 50mg, after a few weeks back up to 100mg.

Oct 2021 - Reduced to 75mg, Dec 2021 (mid) reduced to 50mg , March 2022 - Reduced to 25mg

Oct 2022 - Reduce to 0mg (Immediate withdrawal crying, mood unstable, impending doom, digestive probs, tingling,numbness,burning, brain zaps, insomnia)

Feb 2023 - "Panic attack" lasting 14 hours, 2 weeks later start back on 25mg sertraline, 12 hours later severe 'panic attack' with chest pain, tachycardia, restlessness, hyponatraemia, impending doom, racing thoughts, akathisia mild. Taken to emergency.

March 2023 back up to 50mg (on medical advice), April 75mg, May 100mg. Back to 75mg within a few weeks due to feeling too stimulated and anxious.

Nov 2023 resume taper. 70, 65, 60, 55, 50 (March 2024)

April 45mg, May 41mg, June 37mg, July 34mg Aug 31mg, Sept 28mg, Oct 26mg, Nov 25mg, HOLD

Jan 1st 2025 24mg, Jan 12th 23.5mg, Jan 20th 23mg, Feb 20th 22mg, March 20th 21mg, April 14th 18.9mg, May 5th 17mg, May 28th 15.3mg, July 16th 13.7mg, Aug 26th 12.3mg, Sept 16th 10.5 mg, Sept 22, 10mg, Oct 7th 8.3mg, Nov 4th 8mg, Dec 1st 7.7mg, Dec 26th 7mg 2026 Updose to 7.2mg Mar 20th, Back to 7mg Mar 21. Currently holding

Other supplements: Fish oil, Mg citrate/glycinate 150-300mg per day, Ginkgo biloba daily, womens multi vit/min 3 times week, Vitamin C 1000mg night, valerian/passiflora as needed. B12 as needed. Bone support for osteopaenia (Ca/Mg, K, D)

September 25Sep 25

Author

Thanks @Tracey . Duration and quality both affected. I just use search in Insight Timer. It's amazing how the binaural audios put me so much earlier than before. Enjoy your Yoga Nidra

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day)

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

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October 5Oct 5

Author

I'm really struggling with the drugs Im not tapering. As I've gone lower and lower with Escitalopram the sedating effects of Diazepam and Baclofen have intensified. I feel exhausted all the time and I feel bone weary. Add to this I have TCA induced gnawing hunger. It's a chemical hunger and lasts for a few hours immediately after breakfast. My sleep is no better. After my long stint of intolerable pain which lasted more than 2 months these symptoms are no where near the sheer agony I went through, but these are incapacitating. I have zero energy and feel very very depleted. I'm now unsure which way to go next. I had intended to taper Amitriptyline (due to awful side effects) to hold my current dose, but considering tackling the benzo, but maybe I will lose the buffer it possibly offers for the last 1mg Escitalopram. The terrible muscle spasms may recur once I resume the taper. I estimate I have at least 2 years of tapering (probably more) to taper off.

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day)

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

1

October 5Oct 5

Dear Catbird, I am so sorry that you have been polydrugged so badly.

I hope someone can give you some advice on what to drop next.

Do you know that pharmacist who made the taper app? Would someone from there be able to help you?

I am sorry I have no advice for you, but I wanted you to know that you are heard and cared for.

Wombat

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

October 5Oct 5

Sorry to hear @Catbird, it is awful how many drugs some poor folk end up on. I can see what a juggling act this but be for you. I think as ever listening to your body and reacting is the best. Perhaps if the body is telling you the current balance is too sedative, lift those brakes first. Just do it carefully with little steps and observe. I know the time left to taper seems daunting, thats why like all journeys breaking them down into little chunks, taking each one carefully one at a time not thinking of the next move to reduce the overwhelm. xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

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October 5Oct 5

@Catbird this really is an unfair battle .

If it was me I would do what chippy said and taper of the sedating drug by a little and see if that makes a difference . You can only try and see .

I will be right there with you in this taper battle and I try not to think about how long it will take .

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95 18/7 7.5

4

October 6Oct 6

Author

18 hours ago, Wombat said:
Dear Catbird, I am so sorry that you have been polydrugged so badly.
I hope someone can give you some advice on what to drop next.
Do you know that pharmacist who made the taper app? Would someone from there be able to help you?
I am sorry I have no advice for you, but I wanted you to know that you are heard and cared for.
Wombat

Yes, Alicia. That’s a good idea @Wombat . Thanks 💕

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day)

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

October 6Oct 6

@Catbird I’m so sorry. It sounds like you’re caught between wanting relief from the side effects of the medications you’re still taking but being afraid that changing anything could bring back the terrible symptoms you’ve already endured. That’s such a difficult position to be in.

I hope you can find a path forward without putting you through another ordeal. I’m really hoping things get easier for you.

I am not a health professional in any way, and I do not give medical advice. These are only my opinions. Any decisions about your medical care should be discussed with a qualified medical professional.

Quote of the century: "it's much easier to stop humpty from falling then it is to put him back together again." * as relayed to us by Chippy paraphrasing a comment by Altostrata, the founder of Surviving Antidepressants

If you would like to reach me, please post on my thread and tag @rachelsusan, or post on your thread and tag in the same way, so I will see it. 😀😀😀

Gabapentin reduction. 2026 Transitioned to partial liquid, 100mg in liquid and a 100mg capsule for a total of a 200mg dose. Dose three times a day. April 18 2026 first cut to 195mg (2.5%). May 18, 2026 to 187.5 (3.85%), June 28, 2026 to 185 (1.33%), July 28 to 180 mg (2.7%), Sept. 2, 2026 to 175mg (2.78%),

HISTORY FOR ZOLOFT TAPER

Feb. 2016 to June 2016 - Was on 150mg Zoloft.

Quit Zoloft (Sertraline) June 2016, reinstated 50mg of Zoloft July 2016. From July 2016 to October 2016 went from 50 mg down 2.3 mg. I up-dosed in November 2016 to 12.5 mg. Held there until January 2017 when I started a much slower taper.

STARTING SENSIBLE ZOLOFT TAPERING USING GUIDELINES FROM ANOTHER SITE - WHICH WAS VERY HELPFUL

Dec. 10, 2016 – Switched to liquid Zoloft (sertraline) at 12.5 mg. Held until Jan. 2017, then resumed a slow taper. I tapered continuously from that point onward; however, my detailed taper records begin with Jan. 4, 2020. - Jan. 4, 2020 1.875 mg (6.3%). Jan. 25, 2020 1.75 mg. Feb. 29, 2020 1.625mg (7.10%). Apr. 4, 2020 1.5 mg. May 9, 2020 1.375 mg. June 6, 2020 1.25 mg. (9.10%). July 4, 2020 1.125 mg. (10%). August 15, 2020 1.0 mg. Oct 24, 2020 .875 mg. Nov. 28, 2020 .75mg. Jan 16, 2021 .685mg (8.7%). Feb 13, 2021 .62mg. March 12, 2021 .56mg. May 1, 2021 .375mg. May 29, 2021 .25mg. June 26, 2021 .125mg. July 25, 2021 .065mg. August 22, 2021 .048mg. October 2, 2021 .043mg. October 10, 2021 .038mg. October 23, 2021 .035mg. October 30, 2021 .032mg. Nov. 13, 2021 .030 mg. Dec 4, 2021 .0285 mg. Dec 11, 2021 .0265 mg. Dec 18, 2021 .0246 mg. Dec 25, 2021 .023mg. Jan 1, 2022. 0 mg. OFF COMPLETELY

My thread at SA - https://www.survivingantidepressants.org/forums/topic/12649-☼-rachelsusan-zoloft-on-off-and-reinstated/page/28/

1

October 6Oct 6

Author

3 hours ago, RachelSusan said:
@Catbird I’m so sorry. It sounds like you’re caught between wanting relief from the side effects of the medications you’re still taking but being afraid that changing anything could bring back the terrible symptoms you’ve already endured. That’s such a difficult position to be in.
I hope you can find a path forward without putting you through another ordeal. I’m really hoping things get easier for you.

Thanks @RachelSusan It's more the fact that I'm feeling so drugged and lethargic all the time. Plus I'm not sleeping well and I think the sedative drugs have possibly been potentiated by being in ketosis. Ironically the ketones increase my cognitive capacity, not my physical capacity. I'm really aware of being metabolically healthy due to all the negative effects psych drugs - obesity, diabetes, insulin resistance, ASCVD etc. It's liked trying to wade through mud.

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day)

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

1
1

October 8Oct 8

It's under In The Media ☺️

https://rumble.com/v2wlt7g-the-antidepressant-story-bbc-panorama-documentary.html

I am not a medical professional. My comments are based on my personal experience and information on SA.

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol

"... your strength will be in keeping calm..."-Isaiah 30:15

1

October 9Oct 9

Author

This is going to be insanely difficult. after holding my dose at 1.020mg at the end of April I thought I'd try to taper down to 1mg. The first couple of decreases went okay. My past was 5 days ago I dropped to 1.006mg at today was absolutely terrible. Dissociation, fear hyperaoused , panic, everything seemed unread — I updated to 1.010 and I've had some relief, but I feel exhausted, my head feels full and I'm really terrified I'll never be able to get off Escitalopram. add to that I've got 4 other drugs to taper. the side effects of Amitriptyline are adding to my misery. I'm trying to simplify my regimen so I can taper Amitriptyline to at least half my current dose. This was my plan last December too but I just can't get to the 1mg mark. I'm using to different strengths of Escitaoprram 2mg/ml and 0.2mg/ml to manage the extreme sensitivity

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day)

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

2
3

October 9Oct 9

2 hours ago, Catbird said:
This is going to be insanely difficult. after holding my dose at 1.020mg at the end of April I thought I'd try to taper down to 1mg. The first couple of decreases went okay. My past was 5 days ago I dropped to 1.006mg at today was absolutely terrible. Dissociation, fear hyperaoused , panic, everything seemed unread — I updated to 1.010 and I've had some relief, but I feel exhausted, my head feels full and I'm really terrified I'll never be able to get off Escitalopram. add to that I've got 4 other drugs to taper. the side effects of Amitriptyline are adding to my misery. I'm trying to simplify my regimen so I can taper Amitriptyline to at least half my current dose. This was my plan last December too but I just can't get to the 1mg mark. I'm using to different strengths of Escitaoprram 2mg/ml and 0.2mg/ml to manage the extreme sensitivity

I'm so sorry @Catbird. I hope tomorrow is better after your updose. I can understand your fear and frustration about getting off the drugs. We're all here for you.

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

1

October 9Oct 9

I'm sorry Catbird. I'm glad the updose helped a little. I hope tomorrow will be a better day for you.

Wombat

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

1

October 9Oct 9

Hi @Catbird , I’ve been reading through your thread. You have really “gone through the wringer.” I hope you get relief soon. You are in my thoughts and prayers.

Big Hugs! ❤️🤗🙏

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?) -> 90 mg on Oct 10, 2026

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

1

October 10Oct 10

Author

I feel totally untethered . My partner is away and I’m on my own. Already this morning I’m feeling very scared, agitated and have brain fog. I have mucked up my meds. Not sure if I missed this mornings meds. I’ve just taken them but may have double dosed. I have weekly dosette boxes but still unclear. Very panicky 😱

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg. 2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day)

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

1
1

October 10Oct 10

13 minutes ago, Catbird said:
I feel totally untethered . My partner is away and I’m on my own. Already this morning I’m feeling very scared, agitated and have brain fog. I have mucked up my meds. Not sure if I missed this mornings meds. I’ve just taken them but may have double dosed. I have weekly dosette boxes but still unclear. Very panicky 😱

Dear @Catbird I am so sorry you are struggling right now. I too deal with monophobia. The things these drugs do to us is horrible.

Maybe keep a written record after you take your meds...like a post it on the fridge, just till you get through this rough patch.

You are safe....it is your body reacting to added adrenaline. Can you do anything to distract? Breathe....this too will pass. You did the right thing taking your dose....just give yourself a bit extra time before your next dose.

❤️🙏

I am not a medical professional. My comments are based on my personal experience and information on SA.

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol

"... your strength will be in keeping calm..."-Isaiah 30:15

2

Catbird: Dealing with Polypharmacy

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