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Golden: Tapering Bupropion, then Escitalopram ++

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  • Author

It took me a while to “wrap my brain around” this process. I was very uncertain of my ability to weigh powder from a capsule. However, I’ve ordered what I need to do the above crossover and that is what I will do. I understand that if I get symptoms at any of the steps, I will need to hold until they settle. Based on my history with other meds, I don’t expect that to happen. The above seems to be a very gentle way to crossover.

My brain feels like a very old computer with a slow processor and very little RAM. It eventually gets there but it takes a while. 🤣

Thank you all for your patience and support.

🕊️💞🙏

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

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  • Golden
    Golden

    Update: Although I did not plan to taper Clonazepam yet, that is what I am doing. I am not having any WD problems so far. My main issue continues to be sedation and dizziness. I think this is probabl

  • It took me a while to “wrap my brain around” this process. I was very uncertain of my ability to weigh powder from a capsule. However, I’ve ordered what I need to do the above crossover and that is wh

  • Hi @Golden,   Great to so you here too! Welcome! If you need some assistance at any point, just tag me. I am not around every day, but I will check in at least a few times per week.   

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15 hours ago, Golden said:

It took me a while to “wrap my brain around” this process. I was very uncertain of my ability to weigh powder from a capsule. However, I’ve ordered what I need to do the above crossover and that is what I will do. I understand that if I get symptoms at any of the steps, I will need to hold until they settle. Based on my history with other meds, I don’t expect that to happen. The above seems to be a very gentle way to crossover.

My brain feels like a very old computer with a slow processor and very little RAM. It eventually gets there but it takes a while. 🤣

Thank you all for your patience and support.

🕊️💞🙏

Love this good move Golden!

I understand the analogy I said to my wife I feel like an old ipad that kinda functions but the battery won't hold it's charge, there are rows of pixels out and netflix wont install anymore!

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

On 8/21/2026 at 9:02 AM, Golden said:

It took me a while to “wrap my brain around” this process. I was very uncertain of my ability to weigh powder from a capsule

I never weighed powder. However, I did do a water taper with glass jars and graduated cylinders and liquid syringes and felt like I was in high school chemistry! 😁

It was awkward and uncomfortable at first. After a few weeks, though, I could knock out my daily doses in 5 minutes, no big deal.

I know you'll get there too, @Golden ! Please keep us posted 🙌

2011-2015 - tapered off 300mg of Venlafaxine after 6 years of use

2005-2021 - 450 mg Bupropion daily

2021-2023 - tapered Bupropion to zero 

 

  • Author
16 hours ago, j1290 said:

I did do a water taper with glass jars and graduated cylinders and liquid syringes and felt like I was in high school chemistry! 😁

🤣 I understand. I started this last July with Bupropion. At one time this year, I was doing this with three meds: Bupropion, Atenolol, and Clonazepam.😜 I’m glad I’ve graduated back to just making one liquid of Bupropion. Every 2-3 days, I mix up a batch and put my doses in the little bottles you told me about in the refrigerator. 😊 While I have been holding since April on this dose (to taper those other two drugs 👆, and soon Gabapentin), making the Bupropion liquid doses has just become part of my necessary routine.

17 hours ago, j1290 said:

I never weighed powder

Now I get to increase my high school chemistry skills. 😂 At least this one will be for just a short time (thankfully) of weighing powder as I crossover to my RX liquid.

This journey is a slow, often tedious, process. It’s best (though sometimes difficult) to just focus on taking one day at a time. There is no point in trying to look down the road when everything can change in just a few steps. I may need to be reminded of this in the future! 😂

Thank you @j1290 for staying along side and offering your encouragement! 💞

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

5 hours ago, Golden said:

At one time this year, I was doing this with three meds: Bupropion, Atenolol, and Clonazepam.😜 I’m glad I’ve graduated back to just making one liquid of Bupropion. Every 2-3 days, I mix up a batch and put my doses in the little bottles you told me about in the refrigerator.

You're doing AD shooters!!! 😁👍😆 When I was in college they used to sell shots of something or other in these little vials at bars so whenever I'd take my liquid AD it would remind me of back in the day 😂

If you were doing 3 meds at one time, that's downright impressive! I bet you can knock these things out in nothing flat.

5 hours ago, Golden said:

Now I get to increase my high school chemistry skills. 😂 At least this one will be for just a short time (thankfully) of weighing powder as I crossover to my RX liquid.

ohhhhh OK this is above my pay grade. Let us know how it goes. Hopefully it will be as easy as switching to liquid!

5 hours ago, Golden said:

It’s best (though sometimes difficult) to just focus on taking one day at a time.

I agree with this soooooooooo much. Easier said than done 😁 It really was just one day at a time, some better than others 😜

5 hours ago, Golden said:

. I may need to be reminded of this in the future! 😂

Yeah, me too!! 😎🥂

Everything you're doing sounds calculated and well thought out. You got this, @Golden

2011-2015 - tapered off 300mg of Venlafaxine after 6 years of use

2005-2021 - 450 mg Bupropion daily

2021-2023 - tapered Bupropion to zero 

 

  • Author
On 8/23/2026 at 3:17 PM, j1290 said:

You're doing AD shooters!!!

No, I’m taking my “potion bottle.” 🤣 (from one of our son’s video games when he was young.😉)

On 8/23/2026 at 3:17 PM, j1290 said:

If you were doing 3 meds at one time, that's downright impressive!

It was a pain but it worked. That’s what counts.

💞

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

The potion bottle!!!! 🤣 how could I forget?!?

2011-2015 - tapered off 300mg of Venlafaxine after 6 years of use

2005-2021 - 450 mg Bupropion daily

2021-2023 - tapered Bupropion to zero 

 

  • Author

Gabapentin Crossover Prep Completed! 😜🎉

IMG_9752.jpeg

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

42 minutes ago, Golden said:

Gabapentin Crossover Prep Completed! 😜🎉

WOW! You are a PRO! 👏

1993    Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006      No medication

2006   Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro 

Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin

2016  Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg

November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems.

April 2017 – March 2019       Lexapro 0,6 mg        April 2017 - August 2018       Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step.

March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..)    

Wellbutrin down from 37,5mg to 35,3mg 

October 2019        Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks       Prozac up dosage to 1,2 mg

March 2020     Wellbutrin in 2 steps down from 35,3mg to 33,3mg   Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin  until total off Prozac. 

February 2020 – November 2020   Prozac down in steps from 1,2mg to 0,57mg. 

Jan 2021 :  Prozac down to:  0,55> 0,53>0,51mg,   Feb 0,47mg ,  Mar 0,42mg,   Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg  Long hold of 172 days until March 2022

January 20, 2022:  Wellbutrin from 33,3 to 32,4mg

March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14  Jan 2023 0,13, 0,12, 0,11  Feb 0,10, 0,09 Mar 0,08 ,  June 0,07 , July 0,06,  0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009   Jan 2024 0,008, 0,007,  0,006,  0,005, 0,004, 0,003, 0,002, 0,001, Feb  0,0007.  0,0005,   0,0003, 0,0001,  

Feb 23, 2024:  0,00000

 

Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0         Jan 2025 19,6 mg,  Mar 18,8, Oct 18,68 , 18,55, 18,43, Dec 18,30, Jan 2026 17,93 , Mar 17,7

 

Here is my thread (and tapering history) https://www.survivingantidepressants.org/forums/topic/23288-go2zero-getting-off-wellbutrin-and-prozac/

Whoa this is next level, @Golden !

Great job, and beautiful penmanship 👍

2011-2015 - tapered off 300mg of Venlafaxine after 6 years of use

2005-2021 - 450 mg Bupropion daily

2021-2023 - tapered Bupropion to zero 

 

  • Author
24 minutes ago, Go2zero said:

WOW! You are a PRO! 👏

Thank you @Go2zero for your encouragement. But I’m not really a Pro.. I just persevered. I’m SO GLAD that I only had to do 9 capsules! When I finished, I felt like my brain and nerves were fried. 😂 I’m recovering now so I can complete a few of my “to do” projects today.

12 minutes ago, j1290 said:

Whoa this is next level, @Golden !

Great job, and beautiful penmanship 👍

Thank you @j1290 . Yes! It is next level! 🥺 But I did it, so I guess I’m proud of myself. Beautiful penmanship? 🤣

Love you guys! Thanks for cheering me on!

❤️❤️

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

15 minutes ago, Golden said:

I just persevered.

Exactly this is so good and important. You will definitely get there! 🙏

1993    Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006      No medication

2006   Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro 

Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin

2016  Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg

November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems.

April 2017 – March 2019       Lexapro 0,6 mg        April 2017 - August 2018       Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step.

March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..)    

Wellbutrin down from 37,5mg to 35,3mg 

October 2019        Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks       Prozac up dosage to 1,2 mg

March 2020     Wellbutrin in 2 steps down from 35,3mg to 33,3mg   Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin  until total off Prozac. 

February 2020 – November 2020   Prozac down in steps from 1,2mg to 0,57mg. 

Jan 2021 :  Prozac down to:  0,55> 0,53>0,51mg,   Feb 0,47mg ,  Mar 0,42mg,   Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg  Long hold of 172 days until March 2022

January 20, 2022:  Wellbutrin from 33,3 to 32,4mg

March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14  Jan 2023 0,13, 0,12, 0,11  Feb 0,10, 0,09 Mar 0,08 ,  June 0,07 , July 0,06,  0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009   Jan 2024 0,008, 0,007,  0,006,  0,005, 0,004, 0,003, 0,002, 0,001, Feb  0,0007.  0,0005,   0,0003, 0,0001,  

Feb 23, 2024:  0,00000

 

Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0         Jan 2025 19,6 mg,  Mar 18,8, Oct 18,68 , 18,55, 18,43, Dec 18,30, Jan 2026 17,93 , Mar 17,7

 

Here is my thread (and tapering history) https://www.survivingantidepressants.org/forums/topic/23288-go2zero-getting-off-wellbutrin-and-prozac/

  • Author

@Go2zero @RachelSusan and anyone,

I did the first step in the above crossover last night. I took 90% in capsule (90 mgai) and 10% in RX liquid, 0.2 mL (10 mg). I would not call it successful. After 3 to 3 1/2 hours, I felt it. Big time! I felt drugged! It caught me by surprise. I was getting ready for bed and felt terrible….drugged, wobbly, a bit dizzy, and almost nauseous. I went to bed and several hours later when I got up during the night, I felt fine. I’m also fine today.

This difference is not only a difference in form, from capsules to liquid, but also a difference in manufacturer. This is why I originally wanted to make a homemade liquid from the capsules.

I do not want a repeat of last night. Since I had such a big reaction to the RX liquid, I’m not comfortable taking any more. At least not now.

I’m thinking of trying a repeat of the 90% capsule with 10% of a homemade liquid. I think that may help me determine if it is the form of the drug or possibly the change in manufacturer.

Thoughts?

Edited by Golden

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

  • Author
14 minutes ago, Golden said:

when I got up during the night, I felt fine. I’m also fine today.

I should have said “when I got up during the night, I felt better. This morning I felt “my normal.”

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

4 hours ago, Golden said:

This is why I originally wanted to make a homemade liquid from the capsules.

So, why not do so? Or even with less risk, take out some powder of the capsules. In that way, the form and manufacturer stay exactly the same. That is always the safest route. I know you do not like weighing powder and capsules. But soon it will become a habit. It can be learned fast and easily. If you know the weight of an empty capsule and the weight of the average contents of a capsule, you just need to take out a bit of the powder by weighing. Close the capsule. Throw away the powder you took out. Ready!

1993    Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006      No medication

2006   Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro 

Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin

2016  Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg

November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems.

April 2017 – March 2019       Lexapro 0,6 mg        April 2017 - August 2018       Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step.

March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..)    

Wellbutrin down from 37,5mg to 35,3mg 

October 2019        Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks       Prozac up dosage to 1,2 mg

March 2020     Wellbutrin in 2 steps down from 35,3mg to 33,3mg   Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin  until total off Prozac. 

February 2020 – November 2020   Prozac down in steps from 1,2mg to 0,57mg. 

Jan 2021 :  Prozac down to:  0,55> 0,53>0,51mg,   Feb 0,47mg ,  Mar 0,42mg,   Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg  Long hold of 172 days until March 2022

January 20, 2022:  Wellbutrin from 33,3 to 32,4mg

March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14  Jan 2023 0,13, 0,12, 0,11  Feb 0,10, 0,09 Mar 0,08 ,  June 0,07 , July 0,06,  0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009   Jan 2024 0,008, 0,007,  0,006,  0,005, 0,004, 0,003, 0,002, 0,001, Feb  0,0007.  0,0005,   0,0003, 0,0001,  

Feb 23, 2024:  0,00000

 

Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0         Jan 2025 19,6 mg,  Mar 18,8, Oct 18,68 , 18,55, 18,43, Dec 18,30, Jan 2026 17,93 , Mar 17,7

 

Here is my thread (and tapering history) https://www.survivingantidepressants.org/forums/topic/23288-go2zero-getting-off-wellbutrin-and-prozac/

  • Author

Since I picked up the RX liquid from the pharmacy, I need to talk to my doctor to get a new RX of the capsules.

Tonight I have another problem. I am having severe nerve spasms from my right ear to the top of my head. I have had this in the past and it is always from a mouth sore in the upper back part of my mouth (although I cannot see one yet). I have a procedure that I use for this ..mouth rinses etc. that I will start right after I eat. I hope it does not last long.

🙏🙏🙏

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

@Golden First, I’m sorry for being so late getting back to you.

I can understand why you wouldn’t want to repeat that experience. It sounds like it really caught you off guard, especially since you had been expecting the crossover to be straightforward.

Perhaps for now, it might be best to go back to your original situation for a few days and let things settle. There’s really no reason to rush into another attempt when you’re feeling unsure about what happened.

Then, when you feel ready, you could try the crossover again using your own liquid, as you had originally planned. That might help you get a better sense of whether it was the prescribed liquid itself or the change in manufacturer that made such a difference.

You also could go back over the prescription for the liquid and make sure everything is written down correctly. I’d also double-check with your doctor exactly what you took last night, just so you can be completely sure that the concentration and amount you used were what you thought they were.

You had a pretty strong reaction, and there’s no need to put yourself through that again until you feel comfortable moving forward. You can take this one step at a time. Again I am sorry you went through this. It sounds frightening but I do believe you will get it figured out.

.

Edited by RachelSusan
typo

I am not a health professional in any way, and I do not give medical advice. These are only my opinions. Any decisions about your medical care should be discussed with a qualified medical professional.

Quote of the century: "it's much easier to stop humpty from falling then it is to put him back together again." * as relayed to us by Chippy paraphrasing a comment by Altostrata, the founder of Surviving Antidepressants

 

If you would like to reach me, please post on my thread and tag @rachelsusan, or post on your thread and tag in the same way, so I will see it. 😀😀😀

Gabapentin reduction. 2026 Transitioned to partial liquid, 100mg in liquid and a 100mg capsule for a total of a 200mg dose. Dose three times a day. April 18 2026 first cut to 195mg (2.5%). May 18, 2026 to 187.5 (3.85%), June 28, 2026 to 185 (1.33%), July 28 to 180 mg (2.7%).

 

HISTORY FOR ZOLOFT TAPER

Feb. 2016 to June 2016  - Was on 150mg Zoloft.  

Quit Zoloft (Sertraline) June  2016,  reinstated 50mg of Zoloft July 2016.  From July 2016  to October 2016 went from 50 mg down 2.3 mg. I up-dosed in November 2016 to 12.5 mg. Held there until January 2017 when I started a much slower taper.

STARTING SENSIBLE  ZOLOFT TAPERING USING GUIDELINES FROM ANOTHER SITE - WHICH WAS VERY HELPFUL

Dec. 10, 2016 – Switched to liquid Zoloft (sertraline) at 12.5 mg. Held until Jan. 2017, then resumed a slow taper. I tapered continuously from that point onward; however, my detailed taper records begin with Jan. 4, 2020. - Jan. 4, 2020 1.875 mg (6.3%). Jan. 25, 2020 1.75 mgFeb. 29, 2020 1.625mg (7.10%).  Apr. 4, 2020 1.5 mg.  May 9, 2020 1.375 mg.  June 6, 2020 1.25 mg. (9.10%).  July 4, 2020 1.125 mg. (10%).  August 15, 2020 1.0 mg.  Oct 24, 2020 .875 mg.  Nov. 28, 2020 .75mgJan 16, 2021 .685mg (8.7%).  Feb 13, 2021 .62mg. March 12, 2021 .56mg.  May 1, 2021 .375mg.  May 29, 2021 .25mg. June 26, 2021 .125mg. July 25, 2021 .065mg. August 22, 2021 .048mg.  October 2, 2021 .043mg.  October 10, 2021 .038mg.  October 23, 2021 .035mg.  October 30, 2021 .032mg.  Nov. 13, 2021 .030 mg.  Dec 4, 2021 .0285 mg.  Dec 11, 2021 .0265 mg. Dec 18, 2021 .0246 mg. Dec 25, 2021 .023mg. Jan 1, 2022. 0 mg. OFF COMPLETELY

My thread at SA - https://www.survivingantidepressants.org/forums/topic/12649-☼-rachelsusan-zoloft-on-off-and-reinstated/page/28/

7 hours ago, Golden said:

I hope it does not last long.

Hope it passes soon Golden xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

@Golden I was thinking about you last night and wanted to get this off to you first thing this morning. I can understand why you wouldn't want to repeat what happened. Feeling that drugged must have been really upsetting, especially when you weren't expecting it.

Looking at the crossover plan you posted, I don't see anything wrong with the way you calculated the first step. You took 90 mg in the capsule and 0.2 mL of the liquid, which should give you 100 mg total if the liquid is indeed 50 mg/mL.

Because your reaction was so pronounced, though, I think I'd pause before trying the homemade liquid and just double-check that piece first.

I'd look carefully at the prescription bottle and make sure the concentration is exactly what you think it is, and I'd also check with your doctor or pharmacist to make sure that 0.2 mL really does equal 10 mg.

I actually did something similar when I first started using liquid. I took my syringe and the bottle in to my doctor and went over the dosing with him for my first few cuts, just so I could be sure I was measuring everything correctly. It gave me a lot of peace of mind to know that the numbers and the syringe were all lining up the way I thought they were.

I can certainly understand wanting to figure out whether it was the liquid itself or the different manufacturer. I just think it's worth ruling out anything with the concentration or dosing first, especially since the reaction was so much stronger than you expected. There's no need to rush this.

I really want things to go as smoothly and gently for you as possible. You’ve already put a lot of thought into getting this right. I want the next attempt to be much more uneventful for you.

I am not a health professional in any way, and I do not give medical advice. These are only my opinions. Any decisions about your medical care should be discussed with a qualified medical professional.

Quote of the century: "it's much easier to stop humpty from falling then it is to put him back together again." * as relayed to us by Chippy paraphrasing a comment by Altostrata, the founder of Surviving Antidepressants

 

If you would like to reach me, please post on my thread and tag @rachelsusan, or post on your thread and tag in the same way, so I will see it. 😀😀😀

Gabapentin reduction. 2026 Transitioned to partial liquid, 100mg in liquid and a 100mg capsule for a total of a 200mg dose. Dose three times a day. April 18 2026 first cut to 195mg (2.5%). May 18, 2026 to 187.5 (3.85%), June 28, 2026 to 185 (1.33%), July 28 to 180 mg (2.7%).

 

HISTORY FOR ZOLOFT TAPER

Feb. 2016 to June 2016  - Was on 150mg Zoloft.  

Quit Zoloft (Sertraline) June  2016,  reinstated 50mg of Zoloft July 2016.  From July 2016  to October 2016 went from 50 mg down 2.3 mg. I up-dosed in November 2016 to 12.5 mg. Held there until January 2017 when I started a much slower taper.

STARTING SENSIBLE  ZOLOFT TAPERING USING GUIDELINES FROM ANOTHER SITE - WHICH WAS VERY HELPFUL

Dec. 10, 2016 – Switched to liquid Zoloft (sertraline) at 12.5 mg. Held until Jan. 2017, then resumed a slow taper. I tapered continuously from that point onward; however, my detailed taper records begin with Jan. 4, 2020. - Jan. 4, 2020 1.875 mg (6.3%). Jan. 25, 2020 1.75 mgFeb. 29, 2020 1.625mg (7.10%).  Apr. 4, 2020 1.5 mg.  May 9, 2020 1.375 mg.  June 6, 2020 1.25 mg. (9.10%).  July 4, 2020 1.125 mg. (10%).  August 15, 2020 1.0 mg.  Oct 24, 2020 .875 mg.  Nov. 28, 2020 .75mgJan 16, 2021 .685mg (8.7%).  Feb 13, 2021 .62mg. March 12, 2021 .56mg.  May 1, 2021 .375mg.  May 29, 2021 .25mg. June 26, 2021 .125mg. July 25, 2021 .065mg. August 22, 2021 .048mg.  October 2, 2021 .043mg.  October 10, 2021 .038mg.  October 23, 2021 .035mg.  October 30, 2021 .032mg.  Nov. 13, 2021 .030 mg.  Dec 4, 2021 .0285 mg.  Dec 11, 2021 .0265 mg. Dec 18, 2021 .0246 mg. Dec 25, 2021 .023mg. Jan 1, 2022. 0 mg. OFF COMPLETELY

My thread at SA - https://www.survivingantidepressants.org/forums/topic/12649-☼-rachelsusan-zoloft-on-off-and-reinstated/page/28/

  • Author
13 hours ago, RachelSusan said:

Perhaps for now, it might be best to go back to your original situation for a few days and let things settle. There’s really no reason to rush into another attempt when you’re feeling unsure about what happened.

Yes, I completely agree. Last night I went back to my regular RX capsule and plan to continue for a few days.

13 hours ago, RachelSusan said:

Then, when you feel ready, you could try the crossover again using your own liquid, as you had originally planned. That might help you get a better sense of whether it was the prescribed liquid itself or the change in manufacturer that made such a difference.

These are my thoughts exactly!

13 hours ago, RachelSusan said:

You also could go back over the prescription for the liquid and make sure everything is written down correctly. I’d also double-check with your doctor exactly what you took last night, just so you can be completely sure that the concentration and amount you used were what you thought they were.

3 hours ago, RachelSusan said:

I'd look carefully at the prescription bottle and make sure the concentration is exactly what you think it is, and I'd also check with your doctor or pharmacist to make sure that 0.2 mL really does equal 10 mg.

I can see you are concerned about this, especially with the strong reaction that I had. Me too. Looking at the bottle, it reads: Gabapentin 250 MG/5ML Solution. So 50 mg / 1 mL. And 100 mg / 2 mL. One tenth of 2 mL equals 0.2 mL. I rechecked it all the next morning and also ran it by our adult son who is a computer engineer (lots of math skills 😉). It is all correct. 🤷‍♀️ I talked to the pharmacist and he said the faster absorption didn’t agree with my body.

3 hours ago, RachelSusan said:

There's no need to rush this.

I agree! The nerve spasms from my ear to the top of my head last night (info above 👆), threw another wrench into my system.

10 hours ago, Chippy said:

Hope it passes soon Golden xxx

I think it has passed which is an answer to prayer and a bit of a miracle. I don’t remember it ever clearing so quickly. The downside is that I had to take 1/4 of a hydrocodone tablet twice last night about 8 hours apart. Taking the first dose as soon as I realized how bad it was getting, helped to keep the nerve from getting too stirred up. Today, the nerve spasms are gone but I am dealing with the hangover feeling and head pressure from the pain med.

I’m taking it as easy as possible today and holding everything. One step at a time.

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

  • Author
20 hours ago, Go2zero said:

So, why not do so?

I will try a homemade liquid from the RX capsule after some time to settle again.

20 hours ago, Go2zero said:

Or even with less risk, take out some powder of the capsules. In that way, the form and manufacturer stay exactly the same. That is always the safest route. I know you do not like weighing powder and capsules. But soon it will become a habit. It can be learned fast and easily. If you know the weight of an empty capsule and the weight of the average contents of a capsule, you just need to take out a bit of the powder by weighing. Close the capsule. Throw away the powder you took out. Ready!

I understand what you are saying but it isn’t quite that simple. I can put the bottom half of the empty capsule on the little “dish” that comes with the scales, press the Tare button to zero out the weight, add all of the powder from the RX capsule, put it back on the scales, and take out the extra powder. Sounds simple. In reality the capsule wiggles around & slides towards the center of the dish. The powder sticks together. I can turn the tool with a bit of powder on it upside down inside the capsule but it doesn’t fall off. I have to take the little tweezers and push some of the powder off. All without bumping anything. And of course things get bumped. Then I have to wait for the scales to settle again. Just when I think it is all good to go, the weight on the scales changes.

Can you see my struggle and frustration? This creates too much stress and we all know what stress does to our CNS.

Maybe other powders are easier to work with. Perhaps my hands are not as steady as they used to be. I don’t know. I just know that for me making homemade liquids are much easier and MUCH less time consuming, frustrating, and stressful.

Right now I am pausing everything again to recover. Then I will try a crossover to homemade liquid. If it doesn’t work, I’ll have to weigh the powder in the capsules. 🥺

Thank you for your continued patience and guidance.

🕊️💞🙏

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

12 hours ago, Golden said:

I will try a homemade liquid from the RX capsule after some time to settle again.

Hi @Golden , I think that is the 2nd best way to go. Every change in meds or form can be a trigger, so therefor I like to stay away from changes as much as possible.

The safest route in my opinion is to stay with you capsules and lower the contents of them. But I understand that you find this difficult in practice. There are some simple tricks that could make it easier to do. But I understand that you want to make you own homemade liquid.

If I were you I would still make a crossover from your capsules to the home made liquid. Just to be extra safe. Although the Gabapentin in your home made liquid is the same as in your capsules, there may still be a difference in the uptake in your body.

You can use the capsules that you made before as show in your picture. So no more weighing, only for day 1 (90%). And of course you need to add the right daily amount of home made liquid for the 9 crossover days.

The fact that you had a reaction on day 1 with the RX liquid, may be caused by differences in the active ingredient, the additives or also the amount of active ingredient. I do not prefer changing brands.... Differences could trigger symptoms.

1993    Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006      No medication

2006   Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro 

Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin

2016  Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg

November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems.

April 2017 – March 2019       Lexapro 0,6 mg        April 2017 - August 2018       Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step.

March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..)    

Wellbutrin down from 37,5mg to 35,3mg 

October 2019        Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks       Prozac up dosage to 1,2 mg

March 2020     Wellbutrin in 2 steps down from 35,3mg to 33,3mg   Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin  until total off Prozac. 

February 2020 – November 2020   Prozac down in steps from 1,2mg to 0,57mg. 

Jan 2021 :  Prozac down to:  0,55> 0,53>0,51mg,   Feb 0,47mg ,  Mar 0,42mg,   Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg  Long hold of 172 days until March 2022

January 20, 2022:  Wellbutrin from 33,3 to 32,4mg

March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14  Jan 2023 0,13, 0,12, 0,11  Feb 0,10, 0,09 Mar 0,08 ,  June 0,07 , July 0,06,  0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009   Jan 2024 0,008, 0,007,  0,006,  0,005, 0,004, 0,003, 0,002, 0,001, Feb  0,0007.  0,0005,   0,0003, 0,0001,  

Feb 23, 2024:  0,00000

 

Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0         Jan 2025 19,6 mg,  Mar 18,8, Oct 18,68 , 18,55, 18,43, Dec 18,30, Jan 2026 17,93 , Mar 17,7

 

Here is my thread (and tapering history) https://www.survivingantidepressants.org/forums/topic/23288-go2zero-getting-off-wellbutrin-and-prozac/

  • Author
12 hours ago, Go2zero said:

Every change in meds or form can be a trigger, so therefor I like to stay away from changes as much as possible.

Me too!

12 hours ago, Go2zero said:

If I were you I would still make a crossover from your capsules to the home made liquid. Just to be extra safe.

Absolutely!

12 hours ago, Go2zero said:

Although the Gabapentin in your home made liquid is the same as in your capsules, there may still be a difference in the uptake in your body.

I understand. I am hesitant to try it yet. I need more time to settle. No hurry.

12 hours ago, Go2zero said:

You can use the capsules that you made before as show in your picture. So no more weighing, only for day 1 (90%). And of course you need to add the right daily amount of home made liquid for the 9 crossover days.

My plan exactly! 😊 I’ve already made another 90% capsule for Day 1. My son has helped me again with the math calculations for a new homemade liquid…for when I’m ready to try again.

12 hours ago, Go2zero said:

The fact that you had a reaction on day 1 with the RX liquid, may be caused by differences in the active ingredient, the additives or also the amount of active ingredient. I do not prefer changing brands.... Differences could trigger symptoms.

I understand. My pharmacist said that the faster absorption of the liquid may have been too much for my body to handle. 🤷‍♀️ I had no choice in changing brands since the company that makes my capsules doesn’t make a liquid.

12 hours ago, Go2zero said:

The safest route in my opinion is to stay with you capsules and lower the contents of them. But I understand that you find this difficult in practice. There are some simple tricks that could make it easier to do. But I understand that you want to make you own homemade liquid.

If the homemade liquid causes problems, I will come back to you for these tricks. 😊

I notified the pharmacy and my doctor about the reaction that I had. I had the RX liquid removed and made sure the capsules are still available. They are. 😊

I am still recovering from the nerve spasms on the right side of my head and the results of having to take two 1/4 tablets of hydrocodone for relief. I’m not sure what those two doses did to my CNS but with everything combined, I am not completely back to ”my normal.” I had head pressure all day yesterday and off & on headaches today. I’m trying to take it easy.

I’m also currently taking the regular RX gabapentin capsules since Thursday and until I’m back to normal.

Thank you again for your thoughtful response and support! 💞

2025 / Current:

Bupropion (Wellbutrin) (at least since Jan. 2019) 150 mg -> 131.5 mg on 4-22 -> 112.5 mg on 5-26 -> 93.75 mg on 6-21 -> 87.5 mg on 8-7 -> 77.5mg on 9-1 -> 69 mg on 10-15 -> 61 mg 11-12 -> 60 mg 11-28 -> 54 mg on 12-13-25 -> 53 mg on 4-8-26. HOLD

Escitalopram (Lexapro) 20 mg (consistently since July 2018) -

Gabapentin 100 mg once daily (since June 2014?)

Clonazepam As of Jan. 2019 1.5 mg daily in 3 divided doses as needed. Decreased as I didn’t need as much. March 2025: 1/8 of 0.5 mg tablet (0.0625 mg), 2-3 x daily (0.125 mg - 0.1875 mg daily). -> 2 x daily (0.125 mg daily), -> 1/8 morning0.0625 mg & 1/16 tablet evening (approx. 0.094 mg daily ) March 2026.

Cross over to liquid 0.125 ODT evening dose 0.028125 mg Apr 18; morning dose 0.04375 mg Apr 25, -> 0.040625 mg Apr 26, -> 0.034375 mg May 1, -> 0.028125 mg twice daily (0.05625 mg daily) May 4, -> 0.053125 May 13, -> 0.050 mg May 14, -> 0.04375 mg May 16, -> 0.040625 mg May 19, -> 0.0356 mg 6/2, -> 0.03125 mg June 8, -> 0.0275 mg June 14. -> 0.025 June 16, -> 0.0187 mg June 21, -> 0.0125 mg July 7, -> 0.006 mg July 14.

July 21, 2026 ZERO!

Compounded Bio-Identical HRT: Cream Bi-Est 0.5, Progesterone 150 mg/ML (0.5ML)

Compounded Bio-Identical HRT: Capsule 150 mg each evening 

Metoprolol ER Succinate -> 1/2 of 25 mg tablet 1 x daily on 5/31/25 -> 1/4 tablet on 1-09-2026 -> 1/2 of 25 mg tablet on 2-19. Switched to

Atenolol 4 mg March 4,2026 -> 3 mg Mar.26 -> 2 mg April 18 -> 1 mg May 1, -> zero May 11, 2026.

Supplements:Calcium,D3,K2,Magnesium,Omega3,B-Complex,Biotin,Quercetin,Zinc,C

My profile at Surviving Antidepressants is:

https://www.survivingantidepressants.org/forums/topic/32343-golden-introduction/

“Be joyful in hope, patient in affliction, faithful in prayer.” Romans 12:12

@Golden I am glad to see that you are taking a safe route.... You will get there in such a way ! 😃🤗

1993    Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006      No medication

2006   Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro 

Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin

2016  Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg

November 2016 – April 2017 Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems.

April 2017 – March 2019       Lexapro 0,6 mg        April 2017 - August 2018       Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step.

March 2019 – May 2019 Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..)    

Wellbutrin down from 37,5mg to 35,3mg 

October 2019        Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks       Prozac up dosage to 1,2 mg

March 2020     Wellbutrin in 2 steps down from 35,3mg to 33,3mg   Extreme withdrawal effects during 8 months. Stopped tapering Wellbutrin  until total off Prozac. 

February 2020 – November 2020   Prozac down in steps from 1,2mg to 0,57mg. 

Jan 2021 :  Prozac down to:  0,55> 0,53>0,51mg,   Feb 0,47mg ,  Mar 0,42mg,   Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg  Long hold of 172 days until March 2022

January 20, 2022:  Wellbutrin from 33,3 to 32,4mg

March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25, July 0,24, 0,23, 0,22, 0,21, Aug 0,20, 0,19 Sep 0,18, Oct 0,17. 0,16, 0,15, Nov 0,14  Jan 2023 0,13, 0,12, 0,11  Feb 0,10, 0,09 Mar 0,08 ,  June 0,07 , July 0,06,  0,05, Aug 0,04, 0,03, Sept 0,026, 0,024 Nov 0,022, 0,019, 0,016, 0,013 Dec 0,012, 0,011, 0,010, 0,009   Jan 2024 0,008, 0,007,  0,006,  0,005, 0,004, 0,003, 0,002, 0,001, Feb  0,0007.  0,0005,   0,0003, 0,0001,  

Feb 23, 2024:  0,00000

 

Wellbutrin resume tapering: Apr 2024 31,6mg, 30,8, 30,0 , May 29,1, 28,2, July 23,7, Aug 22,6, 21,4, Dec 21,0, 20,5, 20,0         Jan 2025 19,6 mg,  Mar 18,8, Oct 18,68 , 18,55, 18,43, Dec 18,30, Jan 2026 17,93 , Mar 17,7

 

Here is my thread (and tapering history) https://www.survivingantidepressants.org/forums/topic/23288-go2zero-getting-off-wellbutrin-and-prozac/

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