Thanks everyone. Appreesh.

My appendix burst in the middle of withdrawal. A few days after having surgery and feeling fine, I got hit with a bad wave, similar to acute. It let up after a month or so. I also took prescribed painkillers, but I stopped once the withdrawals hit.

I don't know if it was the painkillers or the appendix but it let up.

Stay the course, it will pass.

On 5/11/2026 at 9:47 AM, Jennings said:

My appendix burst in the middle of withdrawal. A few days after having surgery and feeling fine, I got hit with a bad wave, similar to acute. It let up after a month or so. I also took prescribed painkillers, but I stopped once the withdrawals hit.

I don't know if it was the painkillers or the appendix but it let up.

Stay the course, it will pass.

Oh godddddd

I appreciate that. Yeah i think i’m seeing little glimpses of light through the dark today. Fingers crossed

Alright riddle me this one

Update:

got heat stroke yesterday. Full on. Moved 3/4 of a dump truck of gravel by wheelbarrow to the back of a build site. Super warm out. Sweating buckets, just absolutely demolished. No water to speak of. Had to quit early cause i stopped sweating and was seeing double. Barely made it home and dry heaved on the toilet and then laid on the bathroom tile floor for an hour while my toddler bounced toys off my head. Had a lukewarm shower and then experienced a crazy crazy migraine for like 5 hours.

Next day (today) has felt better than any previous day in this journey. I woke up feeling clear. Like my brain wasnt foggy, it was crisp and thinking straight. No visual issues, no vertigo, no twitches, cramps, halt palps, nothing.

Literally the opposite effect that i think most people in WD would have from sustaining a highly stressed state for a decent many hours and having my body try to shut down on me.

Thoughts? Ideas? The feeling good persists even this evening. Not showing signs of going away

Obviously not something i want to experience again but for such a marked increase in wellbeing it seems like it would be very worth it

2 hours ago, Talltreescoldseas said:

Alright riddle me this one

Update:

got heat stroke yesterday. Full on. Moved 3/4 of a dump truck of gravel by wheelbarrow to the back of a build site. Super warm out. Sweating buckets, just absolutely demolished. No water to speak of. Had to quit early cause i stopped sweating and was seeing double. Barely made it home and dry heaved on the toilet and then laid on the bathroom tile floor for an hour while my toddler bounced toys off my head. Had a lukewarm shower and then experienced a crazy crazy migraine for like 5 hours.

Next day (today) has felt better than any previous day in this journey. I woke up feeling clear. Like my brain wasnt foggy, it was crisp and thinking straight. No visual issues, no vertigo, no twitches, cramps, halt palps, nothing.

Literally the opposite effect that i think most people in WD would have from sustaining a highly stressed state for a decent many hours and having my body try to shut down on me.

Thoughts? Ideas? The feeling good persists even this evening. Not showing signs of going away

Obviously not something i want to experience again but for such a marked increase in wellbeing it seems like it would be very worth it

No answer for you! I think we are all so different. I was expecting you to say you had a big uptick in symptoms after!

I did enjoy the note about your little one bouncing toys off you! Made me chuckle!

I relate to the day you had, Ive had many of those myself! But with out the big reaction (pre drugs)

I don't push myself anywhere near as hard as that, but I too have days where I over exert myself and it doesn't affect me after I have recovered from it.

Withdrawal can absolutely heighten how bad it feels to exert yourself, or get overheated and all those kinds of things, but not everyone then has prolonged setbacks from it.

I've been immensely physically ill, but have never felt that I worsened it by doing what I could, although I've had to stop things because I was feeling worse and worse in the moment.

Just now, Luke said:

I don't push myself anywhere near as hard as that, but I too have days where I over exert myself and it doesn't affect me after I have recovered from it.

@Talltreescoldseas to be fair I am not exercise intolerant, so perhaps you aren't either and the reaction to it is just normal dehydration and exhaustion, but the bit about you feeling better is what gets me!

Hey @Talltreescoldseas , I am also not exercise intolerant and have continued to push my body pretty hard through all this (not to the point of heat stroke of course, but definitely to the point of physical exhaustion). For me, the day after training hard I sometimes feel better and sometimes worse. I’ve basically concluded it’s entirely random. But really glad to hear you had your best day yet — whatever the reason, it’s a great sign!!

4 hours ago, Chippy said:

@Talltreescoldseas to be fair I am not exercise intolerant, so perhaps you aren't either and the reaction to it is just normal dehydration and exhaustion, but the bit about you feeling better is what gets me!

Yeah i’m a bit baffled. I was super exercise intolerant at the start of this so i expected to feel like total ass afterward. I had the “oh shit now i’ve done it” kinda feeling when i got the migraine but yeah! Weirdness

11 minutes ago, Talltreescoldseas said:

Yeah i’m a bit baffled. I was super exercise intolerant at the start of this so i expected to feel like total ass afterward. I had the “oh shit now i’ve done it” kinda feeling when i got the migraine but yeah! Weirdness

Well Im glad for you!

9 hours ago, Talltreescoldseas said:

Alright riddle me this one

Update:

got heat stroke yesterday. Full on. Moved 3/4 of a dump truck of gravel by wheelbarrow to the back of a build site. Super warm out. Sweating buckets, just absolutely demolished. No water to speak of. Had to quit early cause i stopped sweating and was seeing double. Barely made it home and dry heaved on the toilet and then laid on the bathroom tile floor for an hour while my toddler bounced toys off my head. Had a lukewarm shower and then experienced a crazy crazy migraine for like 5 hours.

Next day (today) has felt better than any previous day in this journey. I woke up feeling clear. Like my brain wasnt foggy, it was crisp and thinking straight. No visual issues, no vertigo, no twitches, cramps, halt palps, nothing.

Literally the opposite effect that i think most people in WD would have from sustaining a highly stressed state for a decent many hours and having my body try to shut down on me.

Thoughts? Ideas? The feeling good persists even this evening. Not showing signs of going away

Obviously not something i want to experience again but for such a marked increase in wellbeing it seems like it would be very worth it

Okay so I am going to be "mom" right now. If this ever happens again, get to emergency. It can be life threatening...

Also make your own dehydration drink with salt and sugar/honey/maple syrup.

500 ml water, 1/4 tsp salt, 1 tbsp maple maple syrup.

Please take care of yourself. How is the thumb?

9 hours ago, Talltreescoldseas said:

Super warm out

For Victoria it is...we are so climatized and can't handle the heat. ❤️🙏😊💯

5 hours ago, LostinCanada said:

Please take care of yourself. How is the thumb?

But it made me feel so good the next day!!

Thumbs getting better slowly. Closed up now so less chance of it getting whacked and sending my pain through the roof haha

5 hours ago, LostinCanada said:

For Victoria it is...we are so climatized and can't handle the heat. ❤️🙏😊💯

Truth. I think it was like 22 degrees on the thermometer. Granted i was going in between two buildings with white stucco and it was a solar oven..

17 hours ago, Talltreescoldseas said:

Yeah i’m a bit baffled. I was super exercise intolerant at the start of this so i expected to feel like total ass afterward. I had the “oh shit now i’ve done it” kinda feeling when i got the migraine but yeah! Weirdness

That's a good thing, but I'd still recommend trying to pace yourself.

Certainly you can at least try to get more ontop of things like hydration in advance of activities like this.

Update:

So i had an appointment with my GP (been doing one per month since this shit hit the fan. Actually at the start it was one per week)

My story’s a little different in that it started with WD and i think that whole thing got flipped into an adverse reaction (prednisone)

Similar to steroid injections: https://www.drugs.com/answers/corisone-shot-injection-side-effects-how-long-do-449007.html?hash2=6071dfed680053ad8f2409519aa2cc93&utm_source=email-answers&utm_medium=email&utm_campaign=personal-new-comment-after&utm_content=449007

So maybe i’m not the pure AD WD guy… and maybe this isnt the place where I fully belong but y’all are the best source of support and community that i have, with the symptom of damage most similar, so I hope you let me stay haha

I’ve been stuck on the Epigenetics thing for a long time now as the changes that i’ve made that have made the most difference have always been targeted at methylation/histone acetylation.

Had a bit of an armed (with knowledge) chat to my, admittedly great, doc. He listened to everything I said and went “well yeah, steroids and any drug with a concentric ring structure exerts their effects on dna. That’s how they work. Most people though seem to shake off the changes pretty quickly and their epigenetic changes get re conscripted quickly. It seems like yours didn’t re-write afterward.”

So there we have it for my theory for my specific case. I’ve been having success with

-vit c

-methylfolate

-omega 3

-mac glycinate

-calcium agt

-p5p

That’s the acetylation stack and it’s proven to help things. going to try adding in the histone stack soon to round out the building blocks for my brain and body to make changes and see if I can see more progress.

I’m working with a DVD-R and not a DVD-RW system.

Also i referenced the struggles i had with glucocorticoid drugs and my genetic makeup on the GC/GR system and it’s pretty dysfunctional so it makes a bit of sense that these would effect me so severely

Edited May 30May 30 by Talltreescoldseas

1 hour ago, Talltreescoldseas said:

So maybe i’m not the pure AD WD guy… and maybe this isnt the place where I fully belong but y’all are the best source of support and community that i have, with the symptom of damage most similar, so I hope you let me stay haha

This site isn't really just for ADs, we are supporting those who have had their nervous systems damaged by a whole range of things. As I said before the nervous system doesn't care what the label on the box says, it just gets pissed off when we subject it to these nasty chemicals and repeated changes.

To be more clear, you are welcome here.

I'll not comment on your ongoing experiment! lol :)

9 hours ago, Talltreescoldseas said:

Update:

So i had an appointment with my GP (been doing one per month since this shit hit the fan. Actually at the start it was one per week)

My story’s a little different in that it started with WD and i think that whole thing got flipped into an adverse reaction (prednisone)

Similar to steroid injections: https://www.drugs.com/answers/corisone-shot-injection-side-effects-how-long-do-449007.html?hash2=6071dfed680053ad8f2409519aa2cc93&utm_source=email-answers&utm_medium=email&utm_campaign=personal-new-comment-after&utm_content=449007

So maybe i’m not the pure AD WD guy… and maybe this isnt the place where I fully belong but y’all are the best source of support and community that i have, with the symptom of damage most similar, so I hope you let me stay haha

I’ve been stuck on the Epigenetics thing for a long time now as the changes that i’ve made that have made the most difference have always been targeted at methylation/histone acetylation.

Had a bit of an armed (with knowledge) chat to my, admittedly great, doc. He listened to everything I said and went “well yeah, steroids and any drug with a concentric ring structure exerts their effects on dna. That’s how they work. Most people though seem to shake off the changes pretty quickly and their epigenetic changes get re conscripted quickly. It seems like yours didn’t re-write afterward.”

So there we have it for my theory for my specific case. I’ve been having success with

-vit c

-methylfolate

-omega 3

-mac glycinate

-calcium agt

-p5p

That’s the acetylation stack and it’s proven to help things. going to try adding in the histone stack soon to round out the building blocks for my brain and body to make changes and see if I can see more progress.

I’m working with a DVD-R and not a DVD-RW system.

Also i referenced the struggles i had with glucocorticoid drugs and my genetic makeup on the GC/GR system and it’s pretty dysfunctional so it makes a bit of sense that these would effect me so severely

I wish I didn't have absolute brain fog and that I could understand this. Maybe one day. 🤣🤣🤣

10 hours ago, Talltreescoldseas said:

Mise à jour:

J'avais donc rendez-vous avec mon médecin généraliste (j'en prends un par mois depuis que tout a dégénéré. Au début, c'était un par semaine).

Mon histoire est un peu différente, car elle a commencé par un sevrage et je pense que tout cela a dégénéré en réaction indésirable (prednisone).

Similaire aux injections de stéroïdes : https://www.drugs.com/answers/corisone-shot-injection-side-effects-how-long-do-449007.html?hash2=6071dfed680053ad8f2409519aa2cc93&utm_source=email-answers&utm_medium=email&utm_campaign=personal-new-comment-after&utm_content=449007

Alors, peut-être que je ne suis pas un pur joueur de Féticheur AD… et peut-être que ce n'est pas l'endroit où je me sens vraiment à ma place, mais vous êtes la meilleure source de soutien et la meilleure communauté que j'aie, avec des symptômes de dégâts très similaires, alors j'espère que vous me laisserez rester haha

Je suis bloqué sur la question de l'épigénétique depuis longtemps, car les changements que j'ai effectués et qui ont eu le plus d'impact ont toujours ciblé la méthylation/l'acétylation des histones.

J'ai eu une discussion assez approfondie (et bien informée) avec mon excellent médecin. Il a écouté attentivement tout ce que j'ai dit et m'a répondu : « Eh bien oui, les stéroïdes et tout médicament à structure annulaire concentrique agissent sur l'ADN. C'est leur mode d'action. Cependant, la plupart des gens semblent se remettre assez vite de ces changements et leurs modifications épigénétiques se réinitialisent rapidement. Il semblerait que les vôtres ne se soient pas réécrites par la suite. »

Voilà donc ma théorie pour mon cas particulier. J'ai obtenu de bons résultats avec

-vit c

-méthylfolate

-oméga 3

-mac glycinate

-calcium agt

-p5p

Il s'agit de la pile d'acétylation, et son efficacité est prouvée. Je vais bientôt essayer d'y ajouter la pile d'histones pour compléter les éléments constitutifs nécessaires à mon cerveau et à mon corps, afin de favoriser les changements et de voir si je constate davantage de progrès.

Je travaille avec un système DVD-R et non DVD-RW.

J'ai également évoqué mes difficultés avec les glucocorticoïdes et mon profil génétique concernant le système GC/GR, qui est assez dysfonctionnel ; il est donc logique que ces médicaments m'affectent aussi fortement.

It’s interesting, how did you do that? Do you think it’s appropriate for people on wd, or did you do that in relation to your steroid use?

13 hours ago, poulette38 said:

It’s interesting, how did you do that? Do you think it’s appropriate for people on wd, or did you do that in relation to your steroid use?

Specifically, how did I do what? :)

22 hours ago, Chippy said:

This site isn't really just for ADs, we are supporting those who have had their nervous systems damaged by a whole range of things. As I said before the nervous system doesn't care what the label on the box says, it just gets pissed off when we subject it to these nasty chemicals and repeated changes.

To be more clear, you are welcome here.

I'll not comment on your ongoing experiment! lol :)

Thanks buddy. Damaged I am but still kicking

It might explain why supplements and stuff dont seem to set me off like most of the cases of ssri wd or injury, bit different factors.

And hey! Experiment’s working so far, havent stepped on any serious landmines yet (touch wood) (but not sawblades) and somehow my thumb is healing as well which is good. Wound pretty much fully closed up now

3 hours ago, Talltreescoldseas said:

Thanks buddy. Damaged I am but still kicking

Yeah you are!

3 hours ago, Talltreescoldseas said:

It might explain why supplements and stuff dont seem to set me off like most of the cases of ssri wd or injury, bit different factors

Maybe!? Maybe not!? Plenty don't react to supplements too. Why? We have not idea.

3 hours ago, Talltreescoldseas said:

And hey! Experiment’s working so far, havent stepped on any serious landmines yet (touch wood) (but not sawblades) and somehow my thumb is healing as well which is good. Wound pretty much fully closed up now

Glad to hear this! Yes keep away from the sharp spiney things! Glad you thumbs healing up ok. Mine is still tight and stingy at times 3 years out! Starting to get some sensation back in it though, so thats cool. Time!

7 hours ago, Talltreescoldseas said:

The Specifically, how did I do what? :)

Thanks buddy. Damaged I am but still kicking

It might explain why supplements and stuff dont seem to set me off like most of the cases of ssri wd or injury, bit different factors.

And hey! Experiment’s working so far, havent stepped on any serious landmines yet (touch wood) (but not sawblades) and somehow my thumb is healing as well which is good. Wound pretty much fully closed up now

The table ?

7 hours ago, Talltreescoldseas said:

And hey! Experiment’s working so far, havent stepped on any serious landmines yet (touch wood) (but not sawblades) and somehow my thumb is healing as well which is good. Wound pretty much fully closed up now

4 hours ago, Chippy said:

Yes keep away from the sharp spiney things! Glad you thumbs healing up ok. Mine is still tight and stingy at times 3 years out! Starting to get some sensation back in it though, so thats cool. Time!

I still think we should start a woodworker's recovery group. We could call it Woodworking on Withdrawal!😅

1 hour ago, poulette38 said:

The table ?

Ah forsure. So that came from a program called “genetic lifehacks” it was basically the cheapest way to get my dna data (which i downloaded from one of those ancestry sites. I sequenced it many years ago and they always allow you to download your genetic data) then you run it through another program to actually show your specific mutations and alleles in an easy to read way.

I think it’s helpful for just about everyone to be honest. It’s quite insightful about mood, health, biomarkers to watch out for, things you’re likely to be deficient in, etc

4 minutes ago, Talltreescoldseas said:

Ah forsure. So that came from a program called “genetic lifehacks” it was basically the cheapest way to get my dna data (which i downloaded from one of those ancestry sites. I sequenced it many years ago and they always allow you to download your genetic data) then you run it through another program to actually show your specific mutations and alleles in an easy to read way.

I think it’s helpful for just about everyone to be honest. It’s quite insightful about mood, health, biomarkers to watch out for, things you’re likely to be deficient in, etc

Thank you, we need to go to the lab so that this data can be used on this software? How does it work?

Please @Talltreescoldseas , be very carefull !

Don’t go out in the hot weather! Work or not. I had sunstroke last summer, I almost died! 🥵

13 hours ago, poulette38 said:

Thank you, we need to go to the lab so that this data can be used on this software? How does it work?

The initial test (ancestry.com, 22andme, etc) is just a simple cheek swab that you mail in

Once the do the dna test you get sent a link to check out your geneology and etc on their site. Then you can also download the raw genetics data and just upload that to the other site. Super easy.

12 hours ago, poulette38 said:

Please @Talltreescoldseas , be very carefull !

Don’t go out in the hot weather! Work or not. I had sunstroke last summer, I almost died! 🥵

Heat is life. Almost always working outside all summer (usually 4/5 days a week) and its sometimes 30+ degrees so it’s what I gotta do!