October 6Oct 6 @Finni in same boat as you. Adrenalin shots through me. Pounding tight chest, burning , nausea , pounding headache, . So sorry and I get the fear and waning to call emergency. Aug 2006 - Sertraline 25/50/75/100mg TO June 2019 - Reduced from 100mg to 50mg over a few monthsSept 2019 - Reduced from 50mg to 25mg lasted a week, then went back up to 50mg, after a few weeks back up to 100mg.Oct 2021 - Reduced to 75mg, Dec 2021 (mid) reduced to 50mg , March 2022 - Reduced to 25mgOct 2022 - Reduce to 0mg (Immediate withdrawal crying, mood unstable, impending doom, digestive probs, tingling,numbness,burning, brain zaps, insomnia)Feb 2023 - "Panic attack" lasting 14 hours, 2 weeks later start back on 25mg sertraline, 12 hours later severe 'panic attack' with chest pain, tachycardia, restlessness, hyponatraemia, impending doom, racing thoughts, akathisia mild. Taken to emergency. March 2023 back up to 50mg (on medical advice), April 75mg, May 100mg. Back to 75mg within a few weeks due to feeling too stimulated and anxious. Nov 2023 resume taper. 70, 65, 60, 55, 50 (March 2024)April 45mg, May 41mg, June 37mg, July 34mg Aug 31mg, Sept 28mg, Oct 26mg, Nov 25mg, HOLD Jan 1st 2025 24mg, Jan 12th 23.5mg, Jan 20th 23mg, Feb 20th 22mg, March 20th 21mg, April 14th 18.9mg, May 5th 17mg, May 28th 15.3mg, July 16th 13.7mg, Aug 26th 12.3mg, Sept 16th 10.5 mg, Sept 22, 10mg, Oct 7th 8.3mg, Nov 4th 8mg, Dec 1st 7.7mg, Dec 26th 7mg 2026 Updose to 7.2mg Mar 20th, Back to 7mg Mar 21. Currently holding Other supplements: Fish oil, Mg citrate/glycinate 150-300mg per day, Ginkgo biloba daily, womens multi vit/min 3 times week, Vitamin C 1000mg night, valerian/passiflora as needed. B12 as needed. Bone support for osteopaenia (Ca/Mg, K, D)
October 6Oct 6 Author 2 hours ago, Tracey said:@Finni in same boat as you. Adrenalin shots through me. Pounding tight chest, burning , nausea , pounding headache, .So sorry and I get the fear and waning to call emergency.I’m so sorry Tracey ❤️You’re going to make it through Edited October 6Oct 6 by Finni For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 6Oct 6 Did you go back to the original dosing schedule last night @Finni 2014- April 2025 Escitalopram 10mgApril 2025 - straight swap to Sertraline 50mgDec 2025-Jan 2026 - tapered off Sertraline 50mg - 0mgJun 2026 - Escitalopram 10mg 9 weeksAug - Escitalopram 5mg
October 6Oct 6 Author Just now, Steve1 said:Did you go back to the original dosing schedule last night @FinniYes For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 6Oct 6 Any sign of it calming down @Finni 2014- April 2025 Escitalopram 10mgApril 2025 - straight swap to Sertraline 50mgDec 2025-Jan 2026 - tapered off Sertraline 50mg - 0mgJun 2026 - Escitalopram 10mg 9 weeksAug - Escitalopram 5mg
October 6Oct 6 Author Not yet For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 6Oct 6 Hey @Finni just catching up with your thread. I am very sorry to hear how you are! x It just keeps amazing how unpredictable all this is. A tiny fraction of your dose taken 45 mins early causes all this. Its wild. Your nervous system must be so very sensitive atm. Which we know, but it shows how sensitive it is. I agree with LIC best course of action is as you have done, return to the previous times. Hope this settles soon for you. You really deserve a break from all this now. xxxxx I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.Please take the time to do it today 🙂 https://yellowcard.mhra.gov.ukFor US members details here.
October 6Oct 6 Author 38 minutes ago, Chippy said:Hey @Finni just catching up with your thread. I am very sorry to hear how you are! x It just keeps amazing how unpredictable all this is. A tiny fraction of your dose taken 45 mins early causes all this. Its wild. Your nervous system must be so very sensitive atm. Which we know, but it shows how sensitive it is. I agree with LIC best course of action is as you have done, return to the previous times. Hope this settles soon for you. You really deserve a break from all this now. xxxxxIt seems my body reacted more strongly to shifting 2 mg than it did to trying to reduce .0002 g For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 6Oct 6 So sorry at the severe symptoms you have Finni. I had that kind of akathasia and pacing and unable to sit still and it was horrible. You seem to have a very bad reaction to Mirt like some of us have. I would look at getting a different opinion on tapering. This super slow method may not be best for people having such severe reactions. Mirtazapine Recommended by doctor due to severe ear pain. Was on 30 mg from September 2021 to February 2022. Suffered severe bad reaction of akathisia with pacing and emotional deadness. Tapered from 30mg going down 7.5mg every 2 weeks until last 7.5mg tapered 2.5mg every 2 weeks. Yeah it was fast but I just had to get off this stuff. Completely off from April 2022. Feeling hugely better but still have weird feeling, muscle aches and tiredness.
October 6Oct 6 Thinking of you @Finni and hoping things calm down for you a bit today 🫂💜❤️🩹 I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. Current regimen:Cymbalta - 90 mg/daySeroquel - 12.5 mg/day*holding to stabilize as of Apr 2026 History:Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to presentCymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper offZoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present
October 6Oct 6 Author I really hope I don’t have to relive July and August Deep agitation and nervousness climbing I wish I just would’ve taken stock of how much better I had gotten instead of trying to help myself more. Every time I try to help myself I get worse. For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 6Oct 6 Did Adele respond @Finni 2014- April 2025 Escitalopram 10mgApril 2025 - straight swap to Sertraline 50mgDec 2025-Jan 2026 - tapered off Sertraline 50mg - 0mgJun 2026 - Escitalopram 10mg 9 weeksAug - Escitalopram 5mg
October 6Oct 6 Author 11 minutes ago, Steve1 said:Did Adele respond @FinniNo, she didn’t How are you? For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 6Oct 6 Im trying to keep busy @Finni Is the activation still horrendous? 2014- April 2025 Escitalopram 10mgApril 2025 - straight swap to Sertraline 50mgDec 2025-Jan 2026 - tapered off Sertraline 50mg - 0mgJun 2026 - Escitalopram 10mg 9 weeksAug - Escitalopram 5mg
October 6Oct 6 Author It’s not as bad as yesterdayI feel agitated, but I’m not pacing. It actually feels more like withdrawal like something is missing. For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 6Oct 6 42 minutes ago, Finni said:feel agitated, but I’m not pacing. It actually feels more like withdrawal like something is missing.No pacing is good. I still get that occasionally when under stress. The body is looking for outlets to burn off the adrenaline.Do you have a treadmill? I bought one at the beginning of this and best purchase ever. I can walk and walk and walk ... burning it all off. I just keep an easy pace...6 hours ago, Finni said:eems my body reacted more strongly to shifting 2 mg than it did to trying to reduce .0002 gIt's good to have something to compare it to. 3 hours ago, Finni said:wish I just would’ve taken stock of how much better I had gotten instead of trying to help myself moreHindsight is 20/20.Sometimes it's hard to objectively see the progress. I really messed myself up taking that methylated B12 thinking it would be so helpful. Maybe setting a goal of holding for 3 months, no changes. I also find that I don't like to reinforce the symptoms by writing them down or giving them a voice. I just keep a spreadsheet with the symptoms, rate them 1-10 and that's it...no other words. Doesn't mean you can't rant once in awhile or do an update but I have found, for me, that works. ❤️🙏 I am not a medical professional. My comments are based on my personal experience and information on SA. Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01 TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg 9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol "... your strength will be in keeping calm..."-Isaiah 30:15
October 7Oct 7 @Finni sending some love, it is good yesterday didn't seem as bad as the day before? How is today? xxxxx I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.Please take the time to do it today 🙂 https://yellowcard.mhra.gov.ukFor US members details here.
October 7Oct 7 Author 4 hours ago, Chippy said:@Finni sending some love, it is good yesterday didn't seem as bad as the day before? How is today? xxxxxYesterday was eerily calm lol but I had a weird drugged, nervous feeling.I’m waiting for the other shoe to drop, unfortunately. I don’t think I’m just being paranoid. I think I’ve learned what my body does after a disruption.It’s as if each disruption brings more strongly powered symptoms, including the adverse effects of mirt. And I thought they couldn’t get any stronger.Why didn’t it register in my brain that trying a split would be another disruption? I guess because Dr. Horowitz, Adele Framer and even my vestibular neurologist all mentioned it as this wonderful idea. And on paper, it is such a wonderful idea!Something that had gone away before the split trial was the terror. It’s lurking and keeps trying to come on strong. It’s harrowing and lasted for weeks after the last disruption. I hope I get off easy this time. Edited October 7Oct 7 by Finni For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 7Oct 7 24 minutes ago, Finni said:Yesterday was eerily calm lol but I had a weird drugged, nervous feeling.I’m waiting for the other shoe to drop, unfortunately. I don’t think I’m just being paranoid. I think I’ve learned what my body does after a disruption.Something that had gone away before the split trial was the terror. It’s lurking and keeps trying to come on strong. It’s harrowing and lasted for weeks after the last disruption. I hope I get off easy this time.I'm glad you got a break from the worst of it at least?I've had symptoms lurk and hint for a while but never fully come on so hoping it ends up being something similar for you. 2011-2012: Lexapro 5mg, then rapid taper. Delayed WD but didn't realize the connection at the timeApr 2018: Lexapro 5mg2018: Lexapro 2.5mg. Failed attempts to reduce further over the years by halving dose, skipping dosesJul 29 2025: Monoferric 1000mg iron infusionAug 2 2025: Severe akathisia, WD beginsAug 11 2025: Lexapro CTAug 26 2025: Lexapro 1.06mg reinstatementDec 1 2025: Began using scale to weigh Lexapro doseJul 2026: Increased iron-rich foods in dietAug 9 2026: Further destabilization, interdose WD beginsSupplements: Magnesium 150mg, Melatonin 1mg, Lemon balm tea x 2
October 7Oct 7 56 minutes ago, Finni said:Yesterday was eerily calmThat sounds good Finni, I am pleased about that.57 minutes ago, Finni said:I’m waiting for the other shoe to drop, unfortunately. I don’t think I’m just being paranoid.Lets not assume it will, lets assume it won't. I have it crossed as this is such a small change the distruption will be small too.57 minutes ago, Finni said:Why didn’t it register in my brain that trying a split would be another disruption? I guess because Dr. Horowitz, Adele Framer and even my vestibular neurologist all mentioned it as this wonderful idea. And on paper, it is such a wonderful idea!You can't blame yourself, you are just doing your best making decisions as you see fit at the time, there is no crystal ball Finni. You have had things improve after set backs, it will again. Like I said, maybe this will be not too much of one.59 minutes ago, Finni said:I hope I get off easy this time.Me too xxxx I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.Please take the time to do it today 🙂 https://yellowcard.mhra.gov.ukFor US members details here.
October 7Oct 7 Author 11 minutes ago, Chippy said:such a small change the distruption will be small too.The last disruption involved only a .0002 g change and it was pretty brutal. I can’t believe this. For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 7Oct 7 Hi @Finni forgive my ignorance, how do you get down to 14.79mg. Do you file off a tiny bit of the tablet? 2014- April 2025 Escitalopram 10mgApril 2025 - straight swap to Sertraline 50mgDec 2025-Jan 2026 - tapered off Sertraline 50mg - 0mgJun 2026 - Escitalopram 10mg 9 weeksAug - Escitalopram 5mg
October 7Oct 7 2 minutes ago, Finni said:The last disruption involved only a .0002 g change and it was pretty brutal.I can’t believe this.I know finni, at least this was not a dose change. Hopefully things wont be as long lasting this time x I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.Please take the time to do it today 🙂 https://yellowcard.mhra.gov.ukFor US members details here.
October 7Oct 7 Author 3 minutes ago, Steve1 said:Hi @Finni forgive my ignorance, how do you get down to 14.79mg. Do you file off a tiny bit of the tablet?Yes, I do 🙂I took an average of 10 of the 15 mg pill weight and then reduced by weight of the pill. My 15 mg mirtazapine tablets have an average pill weight of .1040 gAnd now I’m on .1026 g and that’s equal to 14.79 mg For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed2026 (23 July) Mirtazapine 14.79 mg return2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlierSevere activation followed
October 7Oct 7 I see....thanks! Is the active ingredient universally spread throughout the pill? 2014- April 2025 Escitalopram 10mgApril 2025 - straight swap to Sertraline 50mgDec 2025-Jan 2026 - tapered off Sertraline 50mg - 0mgJun 2026 - Escitalopram 10mg 9 weeksAug - Escitalopram 5mg
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