February 13Feb 13 Author 1 hour ago, mars said: Gonna pin this one. GOAT level stuff, here. Thank you again for being a mentor. My "mindset mentor." It's the most important part. I can get very lost and discouraged by the medical terminology and formulas. I've decided, after reading this, that I'm going to steer clear of that focus. I don't have a scientific background or mathematical mind. I don't want to analyze my history to the extent that it takes away my focus from today...and hope for a better tomorrow. After all THIS IS MY LIFE...RIGHT NOW. How can I make it as pleasant as possible, despite suffering? Hey..I think I'm figuring out my place around here. Thanks for helping Jack! Hahaha, I appreciate the kind words @mars! I wouldn’t say it’s “GOAT” level wisdom but once you’ve seen enough, learnt a lot and lived through as much as I have you start seeing things between the lines. Most believe they hold no control over how they’re feeling or thinking through recovery. I disagree with that, and to some degree I challenge that statement. The brain is a powerful organ, and controls our emotions, our thought patterns, it’s the main control centre for most of what keeps us alive. It connects to the whole central nervous system and its ability to function. Our thoughts, our emotions, our way of thinking wires our neural pathways every single day. We have the ability to change how our brain functions simply but reinforcing belief systems and rewiring our mindset, in doing so we can actively rewire our neural pathways. This is known as neuralplasticity, and it means our brains ever changing. I thought I was brain damaged when I first entered withdrawal. By the time I had an MRI of my brain I was at my peak through my protracted state and NOBODY could convince me otherwise that something hadn’t happened to my brain. The symptoms were unexplainable, so severe, so disabling that you would think I’d had a stroke, I was disabled. I’ve mimic’d ever single neurological disorder, disease, condition there is… From MS, to strokes, to TBI, ABI you name it. I’ve had 3 MRI’s with my brain, with contrast, without. There’s nothing wrong with my brain… ZERO structural issues at all. It’s not brain damage, it’s not even nervous system damage. It’s dysregulation, a bad feedback loop. Heightened sensitivity, sensitisation. I have a long history of anxiety, and OCD. I developed health anxiety years ago. I have compulsions to Google, research and spiral down rabbit holes searching for answers about my health, a symptom. My brain will catastrophise simple things like a normal ache, a weird sensation, a lump or a symptom. In doing so, it starts firing alarm bells to my brain that something is wrong, and it starts a loop where my anxiety rises, my brain starts scanning for danger and in doing so symptoms amplify, perpetuate and stay present because I’ve taught my brain a perceived danger that doesn’t exist. If I read online horror stories, look for the worst case scenarios and see myself in these things, I create a false narrative, a story, a timeline before it’s even happened. “Oh no, I have this - which means it’s permanent” or “nobody recovers from this, this will kill me”. All of these little things will tell our brains in the peak of fear instills to our brains that we BELIEVE this, and that it’s going to happen. There’s a domino effect, a rippling effect that occurs when we start to have a keen ability to switch on a flight-or-fight mechanism in our nervous system and brain. Stress occurs, stress can lead to inflammation, an immune system which lowers, in turn leading to sickness, autoimmunity and more. Stress kills… In relation to antidepressant withdrawal, if we were already predisposed to sensitivity, stress, the inability to bounce back from dysregulation in a healthy manner, a protracted drawn out withdrawal is most likely to occur, especially if we FEED the idea that what we’re experiencing is DAMAGE. I don’t think there’s a single person who can come off these drugs which affect our receptors, chemical alteration, and alter our nervous systems to NOT have side effects, TEMPORARY dysregulation from stripping a drug away from a brain and nervous system that became well adjusted on them away? The key word being TEMPORARY. Because for 95% of people, it IS temporary. Why? Because those individuals aren’t creating a negative and false belief system through their withdrawals. They’re also most likely don’t have a history of drug sensitivity, a natural sensitive nervous system to begin with, past trauma, etc etc. The nervous system and brain can learn bad wiring habits, rewire in a negative direction and this is called “maladaptive brain rewiring”. It can happen organically, or it can happen in association with a bad mindset habits, thought patterns and a belief system. If you tell yourself you’ll be sick, you’ll probably end up being sick. Take a drug for the first time and you’re scared you’ll have side effects? Believe it hard enough and you most likely will. This is called nocebo, the opposite to a placebo effect. What if we told ourselves hard enough that we’re not sick, damaged and permanently ill? What if we kept reinforcing safety instead of a sense of danger with everything we do? “I can’t go outside because I get X symptom and I feel like Y” or “I cannot live normally and work and stay out of bed because of X symptom”? The brain learns that response, it learns that action process and what happens? Chances are you go to do it, and the exact reaction happens… Reinforcing belief that you’re right and that’s what is actually wrong with you. What if we started doing the opposite? What if despite the symptom appearing we continue telling our brains “the symptom is just a symptom, I’m not damaged, I’m not ill, I don’t have a condition” what happens then overtime? The brain learns safety, it learns that it doesn’t need to be on alert 24/7 and that we’re safe. In turn, the nervous system settles, you start regulating yourself again and the symptoms over time will fade or vanish. Fear keeps the cycle going, the brain learns based on the fear. Remove the fear? The brain no longer perceives danger… March 2017 - ADR to Prochlorperazine (Stemetil) treatment because of vertigo & vestibular dysfunction.December 2017/January 2018 - started Sertraline (Zoloft) @ 25mg, then 50mg after 4 weeks.March/April 2018 - went from 50 milligrams to 100mg, and stabilised. 2021 - experienced tachyphylaxis (poop out) and went from 100mg to 200 mg. Was neurotoxic for 7 months before going back to 100mg next day. May 2023 - prescribed Agomelatine & Omeprazole to go alongside Sertraline.October 2023 - cold turkey off Agomelatine and Omeprazole, and cut SSRI from 100-50mg, withdrawal began 4 days later.December 2023 - was cross tapered from Sertraline and onto Venlafaxine XR @ 37.5mg increased to 75mg 4 weeks later.July 2024 - tapered off Venlafaxine XR 75mg over 4 weeks to completely heal from protracted withdrawal, been drug free since this period.December 2024 - had a brutal setback from antibiotic + antiviral use. Took 4-5 months to recover to my "normal" baseline.
February 13Feb 13 4 hours ago, Jack said: Why? Because those individuals aren’t creating a negative and false belief system through their withdrawals. I have to say, I disagree with this. I was on the drug short term, and had 0 idea that withdrawal harms were possible. I felt better and better the entire time I was tapering it, and was very happy. Then, shortly after 0mg, I was disabled by a huge array of physical symptoms. Nothing to do with a negative belief system. Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all. Perhaps you should consider this post an artistic work of fiction written for entertainment purposes. Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants 15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects) Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise 1 month taper to 0mg Last dose April 2023 Severe withdrawal syndrome with many physical symptoms Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.
February 14Feb 14 On 2/12/2026 at 11:38 PM, Jack said: challenge that statement. The Amen, brother. January 2001: klonopin, depakote, wellbutrin. Was experiencing overload from: getting married, selling my house, quitting my job, taking care of one grandmother as my other one died. All in the same year. Asked Dr. for support and got called "mixed bi-polar" cuz I didn't have real bi polar symptoms. AND I ACCEPTED THAT. UGH Always felt sick on the meds so I would taper off. Then I would get EXTREME insomnia which I tolerated for several months before I would reinstate some combo. I've done this about 8 times. I'm extremely sensitive so I take really low doses. Still I feel sick. Currently tapering off 1 mg paroxetine. Started at 20. Also on prasozin, 1 mg, Trileptal, 75, seroquel 50.5/6/26 now on 2 mg paroxetine.7/15/26 1.4 mg paroxetine9/24/26 1 mg paroxetine
February 14Feb 14 On 2/13/2026 at 4:17 AM, Luke said: Nothing to do with a negative belief system Of course not, Luke. None of us are to blame for what our bodies do. Also , my prolonged suffering made me very negative. It's like my brain said, " well it's been hard before, So it's going to always be hard." Our minds, I believe, follow a path of least resistance...when I hurt, my brain sort of flows with it. I have had to really WORK for a positive expectation and not listen to the VERY PHYSIOLOGICAL symptoms of fear, doom, and anger, which I believe can be positively affected by my thoughts. Neuroplasticity. Perhaps you don't believe in that, but I must. "It's not me, it's my phsysiolo-gee " is a little rhyme I use when that sensation doesn't lift. NOT EASY. I have a tendency to catastrophize feeling bad. "It's just feeling bad." I now tell myself..healing HURTS, in my experience. We all have different things that "work" for us. Mindset is one Jack and I, apparently, really emphasize . You have a different approach. Good to know. Still, you have helped me a great deal in other ways. Yay!!! Thanks to both you and @Jack for a great discussion! January 2001: klonopin, depakote, wellbutrin. Was experiencing overload from: getting married, selling my house, quitting my job, taking care of one grandmother as my other one died. All in the same year. Asked Dr. for support and got called "mixed bi-polar" cuz I didn't have real bi polar symptoms. AND I ACCEPTED THAT. UGH Always felt sick on the meds so I would taper off. Then I would get EXTREME insomnia which I tolerated for several months before I would reinstate some combo. I've done this about 8 times. I'm extremely sensitive so I take really low doses. Still I feel sick. Currently tapering off 1 mg paroxetine. Started at 20. Also on prasozin, 1 mg, Trileptal, 75, seroquel 50.5/6/26 now on 2 mg paroxetine.7/15/26 1.4 mg paroxetine9/24/26 1 mg paroxetine
February 15Feb 15 Hi @Jack, Thanks for stepping up to be a mentor here. You have been through a lot. I didn't see you on SA but I wasn't that great at connecting with lots of people at that time. When I am in a bad wave (usually a few hours at a time of late) I feel so dreadful physically and emotionally, I understand I am not damaged, however I can't get out of that all encompassing feeling at that very moment and it feels negative. But I don't get into the thoughts of never being well again, just want it to pass relatively quickly. Hope your rough start to the the year improves. I wrote on here that I thought this year would bring stability and peace, however it got off the worst every start for me! Someone told me the Chinese year of the snake is to finish on 17th February and that was all about shedding the old skins and transformation. Then we move the year of the horse. Sounds more hopeful. Aug 2006 - Sertraline 25/50/75/100mg TO June 2019 - Reduced from 100mg to 50mg over a few monthsSept 2019 - Reduced from 50mg to 25mg lasted a week, then went back up to 50mg, after a few weeks back up to 100mg.Oct 2021 - Reduced to 75mg, Dec 2021 (mid) reduced to 50mg , March 2022 - Reduced to 25mgOct 2022 - Reduce to 0mg (Immediate withdrawal crying, mood unstable, impending doom, digestive probs, tingling,numbness,burning, brain zaps, insomnia)Feb 2023 - "Panic attack" lasting 14 hours, 2 weeks later start back on 25mg sertraline, 12 hours later severe 'panic attack' with chest pain, tachycardia, restlessness, hyponatraemia, impending doom, racing thoughts, akathisia mild. Taken to emergency. March 2023 back up to 50mg (on medical advice), April 75mg, May 100mg. Back to 75mg within a few weeks due to feeling too stimulated and anxious. Nov 2023 resume taper. 70, 65, 60, 55, 50 (March 2024)April 45mg, May 41mg, June 37mg, July 34mg Aug 31mg, Sept 28mg, Oct 26mg, Nov 25mg, HOLD Jan 1st 2025 24mg, Jan 12th 23.5mg, Jan 20th 23mg, Feb 20th 22mg, March 20th 21mg, April 14th 18.9mg, May 5th 17mg, May 28th 15.3mg, July 16th 13.7mg, Aug 26th 12.3mg, Sept 16th 10.5 mg, Sept 22, 10mg, Oct 7th 8.3mg, Nov 4th 8mg, Dec 1st 7.7mg, Dec 26th 7mg 2026 Updose to 7.2mg Mar 20th, Back to 7mg Mar 21. Currently holding Other supplements: Fish oil, Mg citrate/glycinate 150-300mg per day, Ginkgo biloba daily, womens multi vit/min 3 times week, Vitamin C 1000mg night, valerian/passiflora as needed. B12 as needed. Bone support for osteopaenia (Ca/Mg, K, D)
February 15Feb 15 7 hours ago, Tracey said: Hope your rough start to the the year improves. I hope so too @Jack. It all takes a huge amount of time, way longer than anyone could really comprehend, but you've seen improvements and it's a bit past the 1.5 years off mark- judging by the stories of others, there is huge precedent for further healing in time and a timescale like this is not abnormal. I hope better days are coming. Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all. Perhaps you should consider this post an artistic work of fiction written for entertainment purposes. Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants 15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects) Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise 1 month taper to 0mg Last dose April 2023 Severe withdrawal syndrome with many physical symptoms Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.
February 16Feb 16 On 2/13/2026 at 3:38 PM, Jack said: Hahaha, I appreciate the kind words @mars! I wouldn’t say it’s “GOAT” level wisdom but once you’ve seen enough, learnt a lot and lived through as much as I have you start seeing things between the lines. Most believe they hold no control over how they’re feeling or thinking through recovery. I disagree with that, and to some degree I challenge that statement. The brain is a powerful organ, and controls our emotions, our thought patterns, it’s the main control centre for most of what keeps us alive. It connects to the whole central nervous system and its ability to function. Our thoughts, our emotions, our way of thinking wires our neural pathways every single day. We have the ability to change how our brain functions simply but reinforcing belief systems and rewiring our mindset, in doing so we can actively rewire our neural pathways. This is known as neuralplasticity, and it means our brains ever changing. I thought I was brain damaged when I first entered withdrawal. By the time I had an MRI of my brain I was at my peak through my protracted state and NOBODY could convince me otherwise that something hadn’t happened to my brain. The symptoms were unexplainable, so severe, so disabling that you would think I’d had a stroke, I was disabled. I’ve mimic’d ever single neurological disorder, disease, condition there is… From MS, to strokes, to TBI, ABI you name it. I’ve had 3 MRI’s with my brain, with contrast, without. There’s nothing wrong with my brain… ZERO structural issues at all. It’s not brain damage, it’s not even nervous system damage. It’s dysregulation, a bad feedback loop. Heightened sensitivity, sensitisation. I have a long history of anxiety, and OCD. I developed health anxiety years ago. I have compulsions to Google, research and spiral down rabbit holes searching for answers about my health, a symptom. My brain will catastrophise simple things like a normal ache, a weird sensation, a lump or a symptom. In doing so, it starts firing alarm bells to my brain that something is wrong, and it starts a loop where my anxiety rises, my brain starts scanning for danger and in doing so symptoms amplify, perpetuate and stay present because I’ve taught my brain a perceived danger that doesn’t exist. If I read online horror stories, look for the worst case scenarios and see myself in these things, I create a false narrative, a story, a timeline before it’s even happened. “Oh no, I have this - which means it’s permanent” or “nobody recovers from this, this will kill me”. All of these little things will tell our brains in the peak of fear instills to our brains that we BELIEVE this, and that it’s going to happen. There’s a domino effect, a rippling effect that occurs when we start to have a keen ability to switch on a flight-or-fight mechanism in our nervous system and brain. Stress occurs, stress can lead to inflammation, an immune system which lowers, in turn leading to sickness, autoimmunity and more. Stress kills… In relation to antidepressant withdrawal, if we were already predisposed to sensitivity, stress, the inability to bounce back from dysregulation in a healthy manner, a protracted drawn out withdrawal is most likely to occur, especially if we FEED the idea that what we’re experiencing is DAMAGE. I don’t think there’s a single person who can come off these drugs which affect our receptors, chemical alteration, and alter our nervous systems to NOT have side effects, TEMPORARY dysregulation from stripping a drug away from a brain and nervous system that became well adjusted on them away? The key word being TEMPORARY. Because for 95% of people, it IS temporary. Why? Because those individuals aren’t creating a negative and false belief system through their withdrawals. They’re also most likely don’t have a history of drug sensitivity, a natural sensitive nervous system to begin with, past trauma, etc etc. The nervous system and brain can learn bad wiring habits, rewire in a negative direction and this is called “maladaptive brain rewiring”. It can happen organically, or it can happen in association with a bad mindset habits, thought patterns and a belief system. If you tell yourself you’ll be sick, you’ll probably end up being sick. Take a drug for the first time and you’re scared you’ll have side effects? Believe it hard enough and you most likely will. This is called nocebo, the opposite to a placebo effect. What if we told ourselves hard enough that we’re not sick, damaged and permanently ill? What if we kept reinforcing safety instead of a sense of danger with everything we do? “I can’t go outside because I get X symptom and I feel like Y” or “I cannot live normally and work and stay out of bed because of X symptom”? The brain learns that response, it learns that action process and what happens? Chances are you go to do it, and the exact reaction happens… Reinforcing belief that you’re right and that’s what is actually wrong with you. What if we started doing the opposite? What if despite the symptom appearing we continue telling our brains “the symptom is just a symptom, I’m not damaged, I’m not ill, I don’t have a condition” what happens then overtime? The brain learns safety, it learns that it doesn’t need to be on alert 24/7 and that we’re safe. In turn, the nervous system settles, you start regulating yourself again and the symptoms over time will fade or vanish. Fear keeps the cycle going, the brain learns based on the fear. Remove the fear? The brain no longer perceives danger… Thanks for sharing that @Jack, I've copy and pasted it in my notes . On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements. 21 April 2025 taper two drugs at once Paxil 4% Seroquel 3.5% per monththat ended up being too much and changed to one drug at a time 13 Jul 2025: 4% Paxil cut29 Jul 2025: 5% Paxil cut 6 Aug 2025: began holdOct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut Holding both drugs to stablizeHolding at Paxil 8.25 mg / Seroquel 6.5Paxil taper22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95 18/7 7.5
February 16Feb 16 Author On 2/13/2026 at 8:17 PM, Luke said: I have to say, I disagree with this. I was on the drug short term, and had 0 idea that withdrawal harms were possible. I felt better and better the entire time I was tapering it, and was very happy. Then, shortly after 0mg, I was disabled by a huge array of physical symptoms. Nothing to do with a negative belief system. I fully agree with you Luke, withdrawal symptoms are real and can be severe. I just don’t think “damage” is the only or necessarily the most helpful framework. I don’t agree with professionals like Josef Witt-Doering constantly preaching to a very easily influenced and traumatised audience that the reason why they’re the way they are is because the drug they took “damaged” and “injured” their brains and nervous systems. He prays on desperate people searching for proper treatment and guidance. There’s no evidence so far that shows antidepressants structurally damage or injure our nervous systems or brains. It’s simply dysregulation, nothing more. Dysregulation which goes into a chronic like state that most likely has a multitude of complex reasons as to why, one of them strongly points to maladaptive brain and nervous system recalibrations after a traumatic experience. The symptoms ARE real, but they don’t originate from a structural abnormality, their root place belongs to hyper-arousal of the brain and nervous system entirely. A sensitised, dysregulated nervous system can get stuck in protection mode. Fear, hyper-vigilance, and avoiding things we think will flare symptoms can unintentionally keep that alarm switched on. Recognising this isn’t blaming anyone or saying symptoms are imagined. It’s acknowledging that there may be additional levers for recovery, like retraining our responses, reducing catastrophic interpretations, and helping the body relearn safety. Some heal and recover without doing anything, without believing they’ll get better. Others need different approaches and methods to achieving homeostasis. There is a lot of anecdotal evidence online, as well as a huge amount of personal testimonies of people significantly reducing or even completely curing symptoms from long-term conditions like chronic pain, fibromyalgia, POTS, CRPS, long COVID, ME/CFS and of course, medication withdrawal simply by learning, and practising nervous system regulation. By changing their relationship to symptoms, rewiring bad neural pathways many have completely recovered from health issues that have been deemed incurable. That doesn’t mean it’s easy or that it’s completely guaranteed for all, but it the evidence clearly shows that significant improvement is possible and that the brain and body can change and heal. Support forums like SA, BenzoBuddies and this one incredibly valuable, they’re a light in the darkness for many, a beacon of hope and for some (including myself at one point) a literal lifeline. But they are more often than not unintentionally reinforcing the idea that we’re permanently injured, damaged. This can create a negative belief system, instil fear, and keep people stuck in a mindset that the medication they took actually damaged them. That sort of ideology can make it harder for a sensitised system to calm down. For some of us, reframing our mindset and changing behaviours might be an important part of how steady and rapid healing process happens. On 2/15/2026 at 5:08 AM, mars said: Of course not, Luke. None of us are to blame for what our bodies do. Also , my prolonged suffering made me very negative. It's like my brain said, " well it's been hard before, So it's going to always be hard." Our minds, I believe, follow a path of least resistance...when I hurt, my brain sort of flows with it. I have had to really WORK for a positive expectation and not listen to the VERY PHYSIOLOGICAL symptoms of fear, doom, and anger, which I believe can be positively affected by my thoughts. Neuroplasticity. Perhaps you don't believe in that, but I must. "It's not me, it's my phsysiolo-gee " is a little rhyme I use when that sensation doesn't lift. NOT EASY. I have a tendency to catastrophize feeling bad. "It's just feeling bad." I now tell myself..healing HURTS, in my experience. We all have different things that "work" for us. Mindset is one Jack and I, apparently, really emphasize . You have a different approach. Good to know. Still, you have helped me a great deal in other ways. Yay!!! Thanks to both you and @Jack for a great discussion! I love your outlook @mars. This is exactly what I’m talking about. Challenge the norm and think outside of the box and I truly believe you’ll prosper at finding different ways to better yourself and promote healing. Staying stuck in a negative mindset and feeding your brain ideas and beliefs that simply aren’t guaranteed and even strongly point to not being true is key. Most people walk this earth not realising that the brain its self can literally manifest and create real physical symptoms based off emotions, trauma and thought processes. Mind body symptoms and disorders are a real thing. Western medicine has known about this for a long time but it’s not widely accepted because it doesn’t fall in line with the framework of how our medical healthcare system runs. And again, I will ALWAYS reiterate that these symptoms are very much REAL, they’re not psychological, they’re real symptoms that disable us but they don’t belong to a diseased, injured, damaged body. Most of us can go run a number of tests, scans which will all show nothing wrong, because nothing is wrong, the symptom is being created, and perpetuated by the brain. If you look hard enough over a long enough period of time you will find patterns to your symptoms, and they will change depending on environments, stress, emotions, and lifestyle. Find a pattern, change it, reinforce safety to your thoughts which in turn forces your brain to rethink, in time that safety promotes regulation to your nervous system, and in doing so gets us out of flight-or-fight mode, and in doing so symptoms will reduce or even vanish in time. 11 hours ago, cheeky said: Thanks for sharing that @Jack, I've copy and pasted it in my notes . No worries! March 2017 - ADR to Prochlorperazine (Stemetil) treatment because of vertigo & vestibular dysfunction.December 2017/January 2018 - started Sertraline (Zoloft) @ 25mg, then 50mg after 4 weeks.March/April 2018 - went from 50 milligrams to 100mg, and stabilised. 2021 - experienced tachyphylaxis (poop out) and went from 100mg to 200 mg. Was neurotoxic for 7 months before going back to 100mg next day. May 2023 - prescribed Agomelatine & Omeprazole to go alongside Sertraline.October 2023 - cold turkey off Agomelatine and Omeprazole, and cut SSRI from 100-50mg, withdrawal began 4 days later.December 2023 - was cross tapered from Sertraline and onto Venlafaxine XR @ 37.5mg increased to 75mg 4 weeks later.July 2024 - tapered off Venlafaxine XR 75mg over 4 weeks to completely heal from protracted withdrawal, been drug free since this period.December 2024 - had a brutal setback from antibiotic + antiviral use. Took 4-5 months to recover to my "normal" baseline.
February 16Feb 16 57 minutes ago, Jack said: A sensitised, dysregulated nervous system can get stuck in protection mode. Fear, hyper-vigilance, and avoiding things we think will flare symptoms can unintentionally keep that alarm switched on. Very true, and very important to remember. 57 minutes ago, Jack said: But they are more often than not unintentionally reinforcing the idea that we’re permanently injured, damaged. I absolutely agree with what you said about mindset and attitude . What you say about the forum I do not agree. I see her all the time how people are encouraging one another that they will heal. Anyway, thank you for your great post! SA Thread: https://www.survivingantidepressants.org/forums/topic/33406-nemina-tapering-escitalopram/AR Thread: https://antidepressantrecovery.org/topic/14-nemina-tapering-escilatopram-and-zolpidem/ Drug History2013 - 2025: Zolpidem 5 mg2015 - Oct 2024: Venlafaxine, Sertralin (Zoloft), Paroxetin (Paxil),duloxtin (cymbalta), Citalopram (Celexa), Escitalopram (Lexapro) and more Current DrugsL-Thyroxin 75, Estrogen, Progesteron 200 Tapering EscitalopramUntil Sept 2024: Setralin/zoloft 75 mgOct 2024: Switch to Escitalopram / Lexapro 2mgThen I tapered over a year from 2mg to 0,32 mg (October 2025). 108 days hold without stabilizing. Resumed taper February 2026:11 Feb 2026 0.314mg 18 Feb 2026 0.307mg 21 Feb 2026 0.302mg09 Mar 2026 0.297mg18 April 2026 0,293 mg18 May 2026 0,285 mg18 June 2026 0,265 mg18 July 2026 0,250 mg18 Aug 2026 0,232 mg18 Sept 2026 0,232 mg (Holding since 19.8.) Tapering Zolpidem: From 5 mg to 0,7 mg in 12 months, then just crumbs for several weeks, now 0! (Jan 2026) Other Supplements Omega 3, Magnesium Glycinate, Vit D, Calcium, L-theanin, Vit C, Vit K2, Selen
February 18Feb 18 On 2/16/2026 at 7:35 PM, Jack said: I fully agree with you Luke, withdrawal symptoms are real and can be severe. I just don’t think “damage” is the only or necessarily the most helpful framework. Which is a valid opinion, definitely. Whatever it is called, people can and do recover. On 2/16/2026 at 7:35 PM, Jack said: There’s no evidence so far that shows antidepressants structurally damage or injure our nervous systems or brains. It’s simply dysregulation, nothing more. On 2/16/2026 at 7:35 PM, Jack said: The symptoms ARE real, but they don’t originate from a structural abnormality, their root place belongs to hyper-arousal of the brain and nervous system entirely. For many people, that's likely true. It's also likely true for withdrawal syndrome generally. However, neurotoxicity from all kinds of sources can cause brain injury, and there are people who think this has happened to them from psychiatric medications: My Brain after Long Term Lexapro: Chemically Induced TBI - Hormones Matter I also had abnormalities show on an MRI that clinicians simply insisted could not and was not relevant. I'll likely never know. The real answer is that we simply do not know the pathology of withdrawal and we do not have measuring tools that can accurately or conclusively measure it. On 2/16/2026 at 7:35 PM, Jack said: There is a lot of anecdotal evidence online, as well as a huge amount of personal testimonies of people significantly reducing or even completely curing symptoms from long-term conditions like chronic pain, fibromyalgia, POTS, CRPS, long COVID, ME/CFS and of course, medication withdrawal simply by learning, and practising nervous system regulation. By changing their relationship to symptoms, rewiring bad neural pathways many have completely recovered from health issues that have been deemed incurable. That doesn’t mean it’s easy or that it’s completely guaranteed for all, but it the evidence clearly shows that significant improvement is possible and that the brain and body can change and heal. Sure, and having watched my sister try these things for years and fight extremely hard to recover from severe ME/CFS and POTS, with far worse symptoms than most would experience from withdrawal, she feels these methods helped her somewhat but she's years into a multi-year battle and they have also not cured her. Working on nervous system regulation, and challenging negative thoughts is good. Reducing stress as much as possible is good, even for a healthy person. On 2/16/2026 at 7:35 PM, Jack said: And again, I will ALWAYS reiterate that these symptoms are very much REAL, they’re not psychological, they’re real symptoms that disable us but they don’t belong to a diseased, injured, damaged body. Most of us can go run a number of tests, scans which will all show nothing wrong, because nothing is wrong, the symptom is being created, and perpetuated by the brain. I have scans with unusual results, blood tests with unusual results and so on, all triggered by one psychiatric drug. I am recovering regardless of this, but still. On 2/13/2026 at 4:38 AM, Jack said: What if we started doing the opposite? What if despite the symptom appearing we continue telling our brains “the symptom is just a symptom, I’m not damaged, I’m not ill, I don’t have a condition” what happens then overtime? The brain learns safety, it learns that it doesn’t need to be on alert 24/7 and that we’re safe. In turn, the nervous system settles, you start regulating yourself again and the symptoms over time will fade or vanish. Fear keeps the cycle going, the brain learns based on the fear. Remove the fear? The brain no longer perceives danger… I'll also add that for a long time I could not feel fear at all, and it's only really in recent months that I've had shortlived bouts of anxiety popping up, even though I'm at my best since ever taking that drug. I appreciate that what you're saying may well be true for some, but I don't think it's universal, and I would also point out that we don't have conclusive evidence that fear causes or prolongs withdrawal symptoms. However, doing everything we can to regulate our nervous systems, thinking and promoting wellbeing and reducing stress is very likely to be a positive thing for recovery. It has been demonstrated to be good for recovery from all sorts of things, like physical injuries, surgery outcomes etc. Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all. Perhaps you should consider this post an artistic work of fiction written for entertainment purposes. Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants 15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects) Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise 1 month taper to 0mg Last dose April 2023 Severe withdrawal syndrome with many physical symptoms Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.
February 18Feb 18 27 minutes ago, Luke said: However, neurotoxicity from all kinds of sources can cause brain injury, and there are people who think this has happened to them from psychiatric medications: My Brain after Long Term Lexapro: Chemically Induced TBI - Hormones Matter I read this link @Luke and as a doctor I understand the scans that were undertaken and what they mean. The EEG and SPECT scan this person had showed changes in brain wave activity and blood perfusion of various areas in the brain. That is still not the same as neuronal cell death and structural damage. The language this person uses is dramatic, but none of their investigations prove permanent injury or structural damage. I'm with @Jack that these drugs cause dysfunction and dysregulation. Where I disagree with Jack is that healing is a matter of learning better nervous system regulation skills. Such a suggestion is never made to someone with a broken leg. At some point, on a cellular level, the body needs to do what it is going to do. I also vehemently disagree with another man I saw on YouTube (linked) who promoted the idea that protracted withdrawal is a learned state and associated with unprocessed unconscious emotions. https://youtu.be/YQulZWZe0yU?si=ByOn3076pKaGlyn1 November 2024 Elvanse for ADHD. Anxiety and jaw clenching, stopped after 4 weeks. Felt fine. January 2025 Medikinet XL Made me depressed and suicidal so stopped after 3 weeks. Felt fine March 2025 Concerta XL Made me depressed and suicidal so stopped after 2 weeks. Felt fine April-May 2025 Amfexa and Methylphenidate instant release, both only worked for an hour so stopped. Felt fine. June 2025 Atomoxetine started slow taper. Immediate hot flushing and feeling sluggish. July-September 2025 Tapered up to 70mg Atomoxetine. Constipation, insomnia, muscle spasms, weird thoughts, mood swings, night sweats, hot flushes, brain fog, dizziness etc October 2025 rapid taper off Atomoxetine. I also had a GA for shoulder surgery the same week I finished meds. Ongoing symptoms ever since, but now also trouble swallowing, difficulty passing urine, muscle twitches, depersonalisation, heavy limbs, emotional blunting, apathy, feeling "wired" and robotic, PGAD. New symptoms February 2026: Nausea and burning head Supplements: B12, folate and Vit D as all were bordering on deficient. Bad reactions to CBD oil, Mag glycinate, Mag L.Threonate and Fish Oil
February 18Feb 18 7 hours ago, Sminismoni said: I read this link @Luke and as a doctor I understand the scans that were undertaken and what they mean. The EEG and SPECT scan this person had showed changes in brain wave activity and blood perfusion of various areas in the brain. That is still not the same as neuronal cell death and structural damage. The language this person uses is dramatic, but none of their investigations prove permanent injury or structural damage. I'm with @Jack that these drugs cause dysfunction and dysregulation. I agree dysfunction or dysregulation is a good description of what has happened to us all. However I disagree that injury is an unsuitable title. Maybe technically as there are no signs of structural damage. But for me it’s more a software injury. I for one definitely feel injured. I’ve never been a very anxious person. I have zero neuro emotional symptoms right now and my mindset and mental health is in a good place. I’m still suffering all the same. I think healing happens without us, all we can do is get out of the way and let it happen. What does this look like? Good diet no more drugs sure and I also agree mindset is important too. It’s always good to work on your mental/well being and it can almost certainly aid healing if your mind isn’t under stress. So avoiding high stress situations and working on your ‘head game’ is definitely a good idea. I think injury is an appropriate title. Withdrawal only covers the temporary symptoms that a person is experiencing from dependance. After some time these pass yet symptoms linger. Additional drug or RI doesn’t ease things and only makes things worse. Pointing to the problem not being dependance. I think recognising this as an injury gives validation to my the individuals experience rather than feeding anxiety that they have caused it in anyway. Good debate guys. Nice and healthy. I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.Please take the time to do it today 🙂 https://yellowcard.mhra.gov.ukFor US members details here.
February 18Feb 18 1 hour ago, Sminismoni said: YouTube (linked) who promoted the idea that protracted withdrawal is a learned state and associated with unprocessed unconscious emotions. https://youtu.be/YQulZWZe0yU?si=ByOn3076pKaGlyn1 I have also seen this before and disagree strongly also @Sminismoni I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.Please take the time to do it today 🙂 https://yellowcard.mhra.gov.ukFor US members details here.
February 18Feb 18 7 hours ago, Sminismoni said: I read this link @Luke and as a doctor I understand the scans that were undertaken and what they mean. The EEG and SPECT scan this person had showed changes in brain wave activity and blood perfusion of various areas in the brain. That is still not the same as neuronal cell death and structural damage. The language this person uses is dramatic, but none of their investigations prove permanent injury or structural damage. I'm with @Jack that these drugs cause dysfunction and dysregulation. From the various posts by that person on that website: "The possibility of a stroke was supported by a CT scan but then later overruled by an MRI." "Shortly after the CFS diagnosis, an MRI revealed white matter lesions and demyelination. The neurologist dismissed a Lexapro connection" They had visible abnormalities on both a CT scan and on multiple MRI scans. An adverse reaction to a large range of drugs can cause neurotoxicity and damage. I don't see why drugs that specifically interact with brain function would be exempt from that- quite the opposite. For most people, "classic" withdrawal syndrome likely is dysregulation. Ruling out the possibility that these drugs can do other harms entirely, without hard evidence, I don't agree with. Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all. Perhaps you should consider this post an artistic work of fiction written for entertainment purposes. Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants 15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects) Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise 1 month taper to 0mg Last dose April 2023 Severe withdrawal syndrome with many physical symptoms Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.
February 19Feb 19 Hi just catching up here! firstly; I struggle big time with Dr Josef, he did a video that was about Compazine injury, one of the very few I could find online, and the terminology is all stuff like ‘it destroyed this women’s life forever’ and ‘her life is over.’ The day I saw that video I was doing OK and watching it sent me in to a wave that lasted a week! I didn’t ask for these Symtoms and I don’t think it’s all mind body stuff, I think my brain has some levelling off to do and stuff that is just beyond anything I can control. A good example of this for me is when I had a 3 week window and felt I was almost healed…then bam 💥 back in to a wave. BUT that sort of video made me feel unsafe and gave me second fear. i know when i come on the groups too much my Symtoms get worse, I know I nearly had a panic attack on the plane today as I remembered a women I had read about who got worse due to going on a plane…. ✈️….that’s all just me making myself worse and giving myself second fear…. so I get very confused where the WD ends and the second fear begins. all I know is my NS is fried and I’ll take all the help I can get to calm it. ⭐️ 🕊️ ☀️ - Compazine injury following surgery used as an anti nausea drug Feb 2023, led to agitation and racing thoughts - tried to cope med free, advised to start Prozac May 2023 20mg - made me worse but was told to persevere, believe I had an adverse reaction. - decided to taper after 6 months of use at 20mg. Went down over 14/15 months to 1.5mg. - February 2025 came off 1.5mg due to feeling good and didn’t know this would lead to such strong WD
February 19Feb 19 On 2/5/2026 at 12:34 PM, Jack said: Been swinging in and out of symptoms for about 90% of January. My sensitivities to histamine have become much more problematic on a daily basis now, I’m struggling to eat almost everything without some sort of reaction, flare in symptoms and it’s driving me nuts. Hi Jack. I am also having a terrible time with histamine and eating almost anything. I feel such relief when I see others struggling with this as it's such a bizarre and lonely withdrawal symptom. What have you found you're able to eat? I know we don't know each other but I'm glad to hear you've had so much progress in your journey, it's always encouraging to see. 2011 - Prozac, don’t remember exact dose but it varied between 10 and 40mg over the years 2012 - 600 mg of lithium 2017 - .5 Ativan, 500 depakote, lithium raised to 900 2023 - February - began tapering Prozac 2024- cross tapered from Prozac to lexapro, finished SSRI taper; began tapering depakote, finished depakote taper; August - tapered off lithium too quickly September/October- attempted to do ill-informed damage control with a few doses each of trazodone, buspar, ativan, xanax, gabapentin October- severe akathisia and crash, back on 900 lithium; 75 mg Seroquel, 10mg propanol 3x daily, 2mg ativan (briefly) 2025 - January- tapered off ativan, cut lithium to 750 February- tapered Seroquel March -tapered propanolol April - Food sensitivity begins June - Lithium 600mg August - Lithium 450 mg; developed severe histamine/MCAS-like issues 2026- holding Lithium at 450 mg for foreseeable future until extreme food sensitivity diminishes Also have been on synthroid since 2017, current dose 150mcg and currently tolerate a vitamin d supplement
February 19Feb 19 On 2/16/2026 at 2:35 PM, Jack said: I fully agree with you Luke, withdrawal symptoms are real and can be severe. I just don’t think “damage” is the only or necessarily the most helpful framework. I don’t agree with professionals like Josef Witt-Doering constantly preaching to a very easily influenced and traumatised audience that the reason why they’re the way they are is because the drug they took “damaged” and “injured” their brains and nervous systems. He prays on desperate people searching for proper treatment and guidance. There’s no evidence so far that shows antidepressants structurally damage or injure our nervous systems or brains. It’s simply dysregulation, nothing more. Dysregulation which goes into a chronic like state that most likely has a multitude of complex reasons as to why, one of them strongly points to maladaptive brain and nervous system recalibrations after a traumatic experience. The symptoms ARE real, but they don’t originate from a structural abnormality, their root place belongs to hyper-arousal of the brain and nervous system entirely. A sensitised, dysregulated nervous system can get stuck in protection mode. Fear, hyper-vigilance, and avoiding things we think will flare symptoms can unintentionally keep that alarm switched on. Recognising this isn’t blaming anyone or saying symptoms are imagined. It’s acknowledging that there may be additional levers for recovery, like retraining our responses, reducing catastrophic interpretations, and helping the body relearn safety. Some heal and recover without doing anything, without believing they’ll get better. Others need different approaches and methods to achieving homeostasis. There is a lot of anecdotal evidence online, as well as a huge amount of personal testimonies of people significantly reducing or even completely curing symptoms from long-term conditions like chronic pain, fibromyalgia, POTS, CRPS, long COVID, ME/CFS and of course, medication withdrawal simply by learning, and practising nervous system regulation. By changing their relationship to symptoms, rewiring bad neural pathways many have completely recovered from health issues that have been deemed incurable. That doesn’t mean it’s easy or that it’s completely guaranteed for all, but it the evidence clearly shows that significant improvement is possible and that the brain and body can change and heal. Support forums like SA, BenzoBuddies and this one incredibly valuable, they’re a light in the darkness for many, a beacon of hope and for some (including myself at one point) a literal lifeline. But they are more often than not unintentionally reinforcing the idea that we’re permanently injured, damaged. This can create a negative belief system, instil fear, and keep people stuck in a mindset that the medication they took actually damaged them. That sort of ideology can make it harder for a sensitised system to calm down. For some of us, reframing our mindset and changing behaviours might be an important part of how steady and rapid healing process happens. Thank you so much for saying this and for calling out Dr. Josef as well as as the negative belief systems that sometimes proliferate on these peer support sites. The idea of damage v dysregulation feels very salient. On the bad days it's very easy to get sucked into feeling those perspectives are fact. I also take heart seeing people recover from conditions like ME/CFS and long covid, they do seem like our cousins in nervous system dysregulation. We are all capable of healing over time. 2011 - Prozac, don’t remember exact dose but it varied between 10 and 40mg over the years 2012 - 600 mg of lithium 2017 - .5 Ativan, 500 depakote, lithium raised to 900 2023 - February - began tapering Prozac 2024- cross tapered from Prozac to lexapro, finished SSRI taper; began tapering depakote, finished depakote taper; August - tapered off lithium too quickly September/October- attempted to do ill-informed damage control with a few doses each of trazodone, buspar, ativan, xanax, gabapentin October- severe akathisia and crash, back on 900 lithium; 75 mg Seroquel, 10mg propanol 3x daily, 2mg ativan (briefly) 2025 - January- tapered off ativan, cut lithium to 750 February- tapered Seroquel March -tapered propanolol April - Food sensitivity begins June - Lithium 600mg August - Lithium 450 mg; developed severe histamine/MCAS-like issues 2026- holding Lithium at 450 mg for foreseeable future until extreme food sensitivity diminishes Also have been on synthroid since 2017, current dose 150mcg and currently tolerate a vitamin d supplement
February 20Feb 20 11 hours ago, pluto said: I also take heart seeing people recover from conditions like ME/CFS and long covid, they do seem like our cousins in nervous system dysregulation. We are all capable of healing over time. Not everybody does fully recover from ME/CFS, especially when it is severe. Some recover, some recover partially and life an ok life always cautiously managing symptoms, and others worsen and stay bad for life. It is good to take heart that recovery from it is possible, but it's a totally different condition from antidepressant withdrawal, is very misunderstood by those who have no experience of it and crucially, is very often used as a throwaway term for being ill but needing to buck your ideas up/regulate your own nervous system/reduce your stress. I have direct experience of a family member being severe and partially recovering in many years, with a significant impact on quality of life still. Comparing severe ME/CFS and antidepressant withdrawal and saying "it's all just dysregulation and your thoughts are holding you back" is unfounded. Here is the reality of ME/CFS: Severe and very severe ME - MEpedia "Severe and very severe ME affects about 25% of people with myalgic encephalomyelitis (ME), with patients being housebound or bedbound at some point in their illness, typically needing to use a wheelchair, unable to do any kind of work or study, and often unable to do basic self-care activities unaided. Some people have died of severe ME..." "A study of 19 bedbound patients with severe ME and orthostatic intolerance by van Campen et al (2020) found an average 27% decrease in blood flow to the brain during a 20 degree tilt table test that lasted just 15 minutes. Some patients could not tolerate the orthostatic symptoms for 15 mins and had to finish the test early. The patients average 35 years of age and had been ill on average 14 years. All the severely ill patients had abnormal drops in blood flow to the brain." "Merryn Crofts was bedbound and unable to eat before she died of very severe ME." "A pilot study of patients with severe CFS/ME in North East England found that even when visiting patients at home, some were unable to complete a questionnaire or to even attempt to stand." I realise this seems negative but ME/CFS sufferers face gigantic stigma and constant denial and dismissal from doctors and society. There is a huge amount of misinformation written about this condition by people with 0 direct experience of it, parroting other misinformation they've read on the internet. Yes, nervous system regulation can be beneficial, but it's both unfair and inaccurate to suggest that ME/CFS is purely based on the sufferer's fear of symptoms, and that therefore psychiatric drug harms must be the same. Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all. Perhaps you should consider this post an artistic work of fiction written for entertainment purposes. Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants 15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects) Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise 1 month taper to 0mg Last dose April 2023 Severe withdrawal syndrome with many physical symptoms Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.
February 20Feb 20 5 hours ago, Luke said: Not everybody does fully recover from ME/CFS, especially when it is severe. Some recover, some recover partially and life an ok life always cautiously managing symptoms, and others worsen and stay bad for life. It is good to take heart that recovery from it is possible, but it's a totally different condition from antidepressant withdrawal, is very misunderstood by those who have no experience of it and crucially, is very often used as a throwaway term for being ill but needing to buck your ideas up/regulate your own nervous system/reduce your stress. I have direct experience of a family member being severe and partially recovering in many years, with a significant impact on quality of life still. Comparing severe ME/CFS and antidepressant withdrawal and saying "it's all just dysregulation and your thoughts are holding you back" is unfounded. Here is the reality of ME/CFS: Severe and very severe ME - MEpedia "Severe and very severe ME affects about 25% of people with myalgic encephalomyelitis (ME), with patients being housebound or bedbound at some point in their illness, typically needing to use a wheelchair, unable to do any kind of work or study, and often unable to do basic self-care activities unaided. Some people have died of severe ME..." "A study of 19 bedbound patients with severe ME and orthostatic intolerance by van Campen et al (2020) found an average 27% decrease in blood flow to the brain during a 20 degree tilt table test that lasted just 15 minutes. Some patients could not tolerate the orthostatic symptoms for 15 mins and had to finish the test early. The patients average 35 years of age and had been ill on average 14 years. All the severely ill patients had abnormal drops in blood flow to the brain." "Merryn Crofts was bedbound and unable to eat before she died of very severe ME." "A pilot study of patients with severe CFS/ME in North East England found that even when visiting patients at home, some were unable to complete a questionnaire or to even attempt to stand." I realise this seems negative but ME/CFS sufferers face gigantic stigma and constant denial and dismissal from doctors and society. There is a huge amount of misinformation written about this condition by people with 0 direct experience of it, parroting other misinformation they've read on the internet. Yes, nervous system regulation can be beneficial, but it's both unfair and inaccurate to suggest that ME/CFS is purely based on the sufferer's fear of symptoms, and that therefore psychiatric drug harms must be the same. I apologize and I completely understand the point you're making. I know many people do not recover fully or do not recover at all from ME/CFS and that there is tremendous stigma. I also not think psychiatric medication withdrawal is all in our heads either. I think the connection I was making is that these are complex poorly misunderstood conditions that seem to have a mind of their own, but I realize it sounded like I was implying that ME/CFS is primarily psychological. I'm sorry for the impact it's had on your family member as well. 2011 - Prozac, don’t remember exact dose but it varied between 10 and 40mg over the years 2012 - 600 mg of lithium 2017 - .5 Ativan, 500 depakote, lithium raised to 900 2023 - February - began tapering Prozac 2024- cross tapered from Prozac to lexapro, finished SSRI taper; began tapering depakote, finished depakote taper; August - tapered off lithium too quickly September/October- attempted to do ill-informed damage control with a few doses each of trazodone, buspar, ativan, xanax, gabapentin October- severe akathisia and crash, back on 900 lithium; 75 mg Seroquel, 10mg propanol 3x daily, 2mg ativan (briefly) 2025 - January- tapered off ativan, cut lithium to 750 February- tapered Seroquel March -tapered propanolol April - Food sensitivity begins June - Lithium 600mg August - Lithium 450 mg; developed severe histamine/MCAS-like issues 2026- holding Lithium at 450 mg for foreseeable future until extreme food sensitivity diminishes Also have been on synthroid since 2017, current dose 150mcg and currently tolerate a vitamin d supplement
February 20Feb 20 2 hours ago, pluto said: I apologize and I completely understand the point you're making. I know many people do not recover fully or do not recover at all from ME/CFS and that there is tremendous stigma. I also not think psychiatric medication withdrawal is all in our heads either. I think the connection I was making is that these are complex poorly misunderstood conditions that seem to have a mind of their own, but I realize it sounded like I was implying that ME/CFS is primarily psychological. I'm sorry for the impact it's had on your family member as well. No need to apologise, I meant it more as a general statement- a lot of discussion in prescribed harm communities uses ME/CFS to make a point without really knowing what it is. Yes, it's certainly true that it's one of many poorly understood conditions. It is also true that for some people with it (but not all), that nervous system regulation exercises can help to a degree. Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all. Perhaps you should consider this post an artistic work of fiction written for entertainment purposes. Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants 15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects) Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise 1 month taper to 0mg Last dose April 2023 Severe withdrawal syndrome with many physical symptoms Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.
February 24Feb 24 Author Been having some incredibly strange, but promising changes in my sexual function as of late. Seems my libido has sky rocketed to astronomical levels for me out of nowhere as of late. Noticed this trend occurring probably around New Years very briefly and then it fell again but it’s been back with a vengeance as of late. I feel like I’m 17 again, like a horny jackrabbit and my partner can’t handle me. 😂 Feels like I’m on steroids or something, I’m sexually wired almost all day and I’ve even been experiencing “blue ball” phenomena occurring. My erections seem fairly mild to medium still, still some mild numbness sensation in my genitals, sex sort of feels okay, not incredibly great. I’m able to reach climax with ease, but the sensation feels like a 6/10. I’m fortunate enough that I still get “morning wood” often, so that shows promising signs that my system IS trying to come back online. And this sudden, explosive increase in my sexual drive is another aspect to that. I’m hoping as time goes on my overall sensation in my genitals will come back, but we’ll see… It’s definitely been a form of PSSD, maybe on the milder side that I’ve been experiencing for at least a year and a half now, but it’s good to see improvements happening. Possibly my dopamine receptors are trying to regulate better? Aside from that, my overall state is very much the same. I’m in and out of lengthy waves and windows like usual. Seems my waves are about 6-7 days long, then a window occurs which is about the same amount of time. Much better overall than my old phase from December of 2023 till about early 2025 it was fairly rapid waves and almost non existent windows. If I had them, they were so short that I barely had time to understand I was having one. No more suicidal ideation is such a big thing for me right now. It’s been a good while since it’s been there, it was a daily occurrence for a good two years almost. I also had it for about a year prior to med use which I think was induced by my adverse reaction back in 2017 to Stemetil. March 2017 - ADR to Prochlorperazine (Stemetil) treatment because of vertigo & vestibular dysfunction.December 2017/January 2018 - started Sertraline (Zoloft) @ 25mg, then 50mg after 4 weeks.March/April 2018 - went from 50 milligrams to 100mg, and stabilised. 2021 - experienced tachyphylaxis (poop out) and went from 100mg to 200 mg. Was neurotoxic for 7 months before going back to 100mg next day. May 2023 - prescribed Agomelatine & Omeprazole to go alongside Sertraline.October 2023 - cold turkey off Agomelatine and Omeprazole, and cut SSRI from 100-50mg, withdrawal began 4 days later.December 2023 - was cross tapered from Sertraline and onto Venlafaxine XR @ 37.5mg increased to 75mg 4 weeks later.July 2024 - tapered off Venlafaxine XR 75mg over 4 weeks to completely heal from protracted withdrawal, been drug free since this period.December 2024 - had a brutal setback from antibiotic + antiviral use. Took 4-5 months to recover to my "normal" baseline.
February 27Feb 27 Well congrats, woody!!! Lol I have none of your enthusiasm but the good news gives me hope! My regards to your partner!!! January 2001: klonopin, depakote, wellbutrin. Was experiencing overload from: getting married, selling my house, quitting my job, taking care of one grandmother as my other one died. All in the same year. Asked Dr. for support and got called "mixed bi-polar" cuz I didn't have real bi polar symptoms. AND I ACCEPTED THAT. UGH Always felt sick on the meds so I would taper off. Then I would get EXTREME insomnia which I tolerated for several months before I would reinstate some combo. I've done this about 8 times. I'm extremely sensitive so I take really low doses. Still I feel sick. Currently tapering off 1 mg paroxetine. Started at 20. Also on prasozin, 1 mg, Trileptal, 75, seroquel 50.5/6/26 now on 2 mg paroxetine.7/15/26 1.4 mg paroxetine9/24/26 1 mg paroxetine
March 1Mar 1 It sounds like you're experiencing a range of improvements, even though it's non linear. At 1.5 years (roughly) off of medication, this seems to be fairly in line with a lot of others' experiences. Hopefully the improvements become more consistent in time. Thank you for the update. Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all. Perhaps you should consider this post an artistic work of fiction written for entertainment purposes. Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants 15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects) Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise 1 month taper to 0mg Last dose April 2023 Severe withdrawal syndrome with many physical symptoms Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.
March 1Mar 1 Author On 2/28/2026 at 5:51 AM, mars said: Well congrats, woody!!! Lol I have none of your enthusiasm but the good news gives me hope! My regards to your partner!!! I appreciate your words! 3 hours ago, Luke said: It sounds like you're experiencing a range of improvements, even though it's non linear. At 1.5 years (roughly) off of medication, this seems to be fairly in line with a lot of others' experiences. Hopefully the improvements become more consistent in time. Thank you for the update. Slow and steady wins the race. Up and down fluctuations but it’s showing good signs of improvement and healing nonetheless! March 2017 - ADR to Prochlorperazine (Stemetil) treatment because of vertigo & vestibular dysfunction.December 2017/January 2018 - started Sertraline (Zoloft) @ 25mg, then 50mg after 4 weeks.March/April 2018 - went from 50 milligrams to 100mg, and stabilised. 2021 - experienced tachyphylaxis (poop out) and went from 100mg to 200 mg. Was neurotoxic for 7 months before going back to 100mg next day. May 2023 - prescribed Agomelatine & Omeprazole to go alongside Sertraline.October 2023 - cold turkey off Agomelatine and Omeprazole, and cut SSRI from 100-50mg, withdrawal began 4 days later.December 2023 - was cross tapered from Sertraline and onto Venlafaxine XR @ 37.5mg increased to 75mg 4 weeks later.July 2024 - tapered off Venlafaxine XR 75mg over 4 weeks to completely heal from protracted withdrawal, been drug free since this period.December 2024 - had a brutal setback from antibiotic + antiviral use. Took 4-5 months to recover to my "normal" baseline.
March 7Mar 7 Jack your partner must be exhausted 🥴🤣 I’m pleased about the SI. i have looping thoughts about life having no meaning and some SI but I don’t know if it’s true SI as I 100% don’t want to do it, so I get confused what to call it: intrusive thoughts I guess. 100% came from the Prochloperazine injury for me and the the Prozac made it worse. In a window those thoughts totally go. for me they seem to be linked to this intense burn/anxiety I get on my solar plexus. When that’s bad the thoughts go through the roof, when it’s better they ease off…. i guess that feeling is so unbearable it triggers the thoughts now like a well worn pathway. I’m not even sure. it’s really hopeful for me to see you are making improvements at this stage, I’m 12 months off now so a little behind you. I’ve had some good windows but still in this very none linear windows and waves pattern. fingers crossed you will make lots more progress over the coming months 🙏 - Compazine injury following surgery used as an anti nausea drug Feb 2023, led to agitation and racing thoughts - tried to cope med free, advised to start Prozac May 2023 20mg - made me worse but was told to persevere, believe I had an adverse reaction. - decided to taper after 6 months of use at 20mg. Went down over 14/15 months to 1.5mg. - February 2025 came off 1.5mg due to feeling good and didn’t know this would lead to such strong WD
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