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Wombat: Paroxetine high dose, 25+ years

Wombat
Wombat
in Introductions & Ongoing Recoveries

Featured Replies

38 minutes ago, Wombat said:

I don't mind you double checking, sometimes we miss things.

Yep, always good to double check.

LIC & others have quizzed me many times over the years, and I have appreciated the 2nd set of eyes.

39 minutes ago, Wombat said:

The only question mark would be the accuracy. I am doing everything the same, but maybe it could be better? Not sure.

Why don't you talk us through exactly what you are doing, step by step...I know it appears somewhere in your topic.

List each step on a separate line (if you are comfortable, of course). Let's see if anything jumps out.

I'd be very interested in the equipment you use. Syringe sizes, if they've been changed etc.

39 minutes ago, Wombat said:

maybe it could be better?

This was the reason I went to a micropipette. I knew how sensitive I could be to changes, and I wanted to be certain of accuracy.

When you reduce by 5%, it can be a really small reduction with a syringe, depending on the size you use. Syringes just ended up not working for me.

I figured if the likes of Dr Horowitz used a micropipette, it tells you something about the importance of accuracy.

As LIC said, your drug is a beast, so let's be certain of the accuracy.

44 minutes ago, LostinCanada said:

Your body probably hasn't caught up yet....this drug is a beast.

But this is absolutely a very real possibility as well.

Multi-year hyperbolic Bintellix taper

7 Dec 25: 0.42mg

7 Mar 26: 0.44mg (+5%)

29 Mar 26: 0.34mg (trying to follow the "slow" Maudsley Guide)

28 Apr 26: 0.24mg

24 May 26: 0.14mg

29 Jun 26: 0.10mg

31 Jul 26: 0.07mg

28 Aug 26: 0.035mg

22 Sep 26: 0.018mg

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  • Wombat
    Wombat

    I have been holding for just over 3 weeks and not got back to WD Normal. Today is a particularly bad day. I will continue to hold until this all passes. The last drop was only 2%. Not sure why it is

  • Vince
    Vince

    One of the reasons I chose a 1:4 (paroxetine in mgai to water in ml) ratio is for more accuracy with a 10ml syringe. Here's my math with a visual example. Example A shows a 1:1 ratio, where a small de

  • Wombat
    Wombat

    Update: 1 August 2026 I have dropped a total of 5.69% this month (over 3 weeks). I will now hold for 2 weeks and, all going well, recommence dropping on 15th August. Have had some instability along

Posted Images

  • Author

Ok.

To start with I have a 40ml Medicine cup which I put 40ml of water and then weighed to double check it was 40ml. I put a mark at that level, which was very close to the mark on the cup. I then also used my 10ml syringe to measure out 40ml of water and it also came to the mark. So I am confident that my 40ml of water is correct.

  1. Put tablet into measuring cup and crush with end of teaspoon

  2. Add 40ml water using 4 x 10ml syringe. Double check with mark on cup

  3. Stir

  4. Sit for 30mins

  5. Stir and take 1 x 10ml using 10ml syringe

  6. Stir and take 1 x 4ml using 10ml syringe

  7. Stir and take 1 x 0.6ml using 2.5ml syringe

  8. Total 14.6ml (equals 7.3mgai)

The syringes used are "medicina reusable oral tip syringe".

I am still using the same batch I bought in March.

You are right, getting the 0.6ml can be tricky to get it perfect.

It could be as simple as that.

I can't remember at which dose I started using the 2.5ml syringe. I'll see if I have it written in my notes.

One more thing .... I don't weigh my tablet, which as LostinCanada said could be an issue too. Although up until now, that has seemed to be ok.

Edited by Wombat

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58 

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

 

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

 

  • Author

I would like to ask some questions regarding the micropipette.

If I can find it, I plan to get the one LostinCanada recommends in the tapering section.

BRAND Transferpette S Variable, 1000-10000 µL D-10000 DE-M

I would get the 1000 to 10000ul which would be 1ml to 10ml.

Do you know if I will be able to measure the .00 amounts? Eg. 9.26. I know I could get the 9, just wasn't sure if it would do after the decimal place.

So for example, I am on 14.6ml

I would take 10000ul + 4600ul??? Maybe.

And then if I wanted to do 2 decimal places could I do that?

Sorry, convoluted question. Basically just wondering how many decimal places this one can do. Hope it makes sense.

Edited by Wombat

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58 

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

 

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

 

44 minutes ago, Wombat said:

I would like to ask some questions regarding the micropipette.

If I can find it, I plan to get the one LostinCanada recommends in the tapering section.

BRAND Transferpette S Variable, 1000-10000 µL D-10000 DE-M

I would get the 1000 to 10000ul which would be 1ml to 10ml.

Do you know if I will be able to measure the .00 amounts? Eg. 9.26. I know I could get the 9, just wasn't sure if it would do after the decimal place.

So for example, I am on 14.6ml

I would take 10000ul + 4600ul??? Maybe.

And then if I wanted to do 2 decimal places could I do that?

Sorry, convoluted question. Basically just wondering how many decimal places this one can do. Hope it makes sense.

@AlmostOff uses this brand. He can help.💯

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol

 

"... your strength will be in keeping calm..."-Isaiah 30:15

    •
    • Love 1
    38 minutes ago, LostinCanada said:

    He can help.💯

    Will come back to you after work...

    Multi-year hyperbolic Bintellix taper

    7 Dec 25: 0.42mg

    7 Mar 26: 0.44mg (+5%)

    29 Mar 26: 0.34mg (trying to follow the "slow" Maudsley Guide)

    28 Apr 26: 0.24mg

    24 May 26: 0.14mg

    29 Jun 26: 0.10mg

    31 Jul 26: 0.07mg

    28 Aug 26: 0.035mg

    22 Sep 26: 0.018mg

    • Author

    No problem. No hurry. I appreciate your help.

    1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

    Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

    Beginning 2023, start micro tapering from 30mg

    End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58 

    2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

    27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

     

    Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

     

    7 hours ago, Wombat said:

    5.5% for the month. Held for 2 weeks and then dropped 2%.

    @Wombat that's a lot and mayby it's just caught up on you .

    I was fine dropping 3.% per month for 3 months with no major symptoms then Bam , I've had to hold now fir 3 months . Just hold that's what I'm doing .

    On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

     

    21 April 2025 taper two drugs at once 

    Paxil 4% Seroquel 3.5% per month

    that ended up being too much and changed to one drug at a time  

    13 Jul 2025: 4% Paxil cut

    29 Jul 2025: 5% Paxil cut 

    6 Aug 2025: began hold

    Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

    23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

     Holding both drugs to stablize

    Holding at Paxil 8.25 mg / Seroquel 6.5

    Paxil taper

    22/4 8.23  29/4 8.20  5/5 8.15 13/5 8.05  3/6 8 11/6 7.95 18/7 7.5

    • Author

    Thanks Cheeky, that's what LostinCanada thinks too.

    Yep. Holding is the plan for the next little while.

    Wombat

    1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

    Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

    Beginning 2023, start micro tapering from 30mg

    End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58 

    2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

    27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

     

    Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

     

    •
    • Love 1
    7 hours ago, Wombat said:

    I would like to ask some questions regarding the micropipette.

    If I can find it, I plan to get the one LostinCanada recommends in the tapering section.

    BRAND Transferpette S Variable, 1000-10000 µL D-10000 DE-M

    I would get the 1000 to 10000ul which would be 1ml to 10ml.

    Do you know if I will be able to measure the .00 amounts? Eg. 9.26. I know I could get the 9, just wasn't sure if it would do after the decimal place.

    So for example, I am on 14.6ml

    I would take 10000ul + 4600ul??? Maybe.

    And then if I wanted to do 2 decimal places could I do that?

    Sorry, convoluted question. Basically just wondering how many decimal places this one can do. Hope it makes sense.

    Hey Wombat, you are spot on here, your proposed Micro Pipette can measure 1000-10,000 uL

    So as you said 14.6mL would be 10,000 & 4,600 uL

    If you wanted to measure 14.67mL would be 10,000 & 4670uL

    IMO this is the one to go for sure.

    I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

     

    If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

    Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

    For US members details here.

    • Author

    Oh perfect. Thank you Chippy.

    1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

    Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

    Beginning 2023, start micro tapering from 30mg

    End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58 

    2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

    27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

     

    Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

     

    •
    • Like 1

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