Huge congrats @Marie!! Finishing your taper is a huge deal and you should be very proud 😊. Especially since you tapered so patiently and seem to have avoided the worst of WD. You inspire us all, and one day I hope to be in your shoes!

I hope that this next step at 0mg goes well, please do drop in and let us know how you're doing when you can.

16 hours ago, Marie said:

Hello everyone. On 8/11/26 I took my last dose of mirtazapine. Last night there was no dose to take. What a pleasure! I slept just like I have been sleeping lately, some wakeups, little early, but who cares. I have been noticing I have been getting good chunks of REM sleep every night. My tummy is a little nauseous.

I have been having uti symptoms and tested positive on home test. When to the doc and got an antibiotic. I've also been nursing sinus symptoms for a month. There has been smoke from wildfires and additional pollution with very humid weather. I could have a sinus infection too. The thing is though both of these could just be mirt paying me back for tapering. I will take the a/b and see if I improve. I'll just chill at home with no plans and try to take extra good care of myself. To those out there tapering, keep going things will get better.

I think I have a good shot at getting healed completely. I'm curious to see how long it will take. My long ass taper may help. Mood is good and I remain positive. I'll check back from time to time. Be well. Marie.

So happy to see Marie, amazing news. Please make sure you come back, and once you are happy things are good for you, give it a good 6-12 months, please rememember to write a sucess story here. They mean so much to us all! xxxxx

Hello everyone. I just wanted to give an update on my time being off mirt. I've been tapering since 2020. Today it's been over a month and I am doing pretty good. I did have a uti right when I got off with two rounds of antibiotics. I twisted my hip and had to go on prescribed anti-inflammatorys. They all made me sick but I got through it.

Sleep is good, some poorer nights, some good nights, and some magical nights (7/8 hours). I've had a couple fantastic windows. The only thing that is bothering me is my gut. I'm two weeks plus off a/b's. I had been constipated for over a week, gassy, bloaty, and a bit nauseous. I finally figured out to take prunes and they started helping some. Today, however, it changed to loose bowels and more nausea. It's so weird, it's my only withdrawal symptom. Appetite is poor, so I guess I'll lose some weight. Anyone have any suggestions for messed up stomach? How long did it take post taper to stomach issues to resolve?

I had tickets for a concert and I almost cancelled a couple nights ago, Creedence Clearwater Revival and Steve Winwood. OMG I did not expect such a great concert. It was at the beach too so I got a lot of fresh air. I almost cancelled, but I am so glad I went.

If I could just get over the stomach thing I will be golden. Be well. Marie.

Hey @Marie thank you for the update. I am glad things are going reasonably well since your stopped. I don't have much practical adivce about your gut issues other than the things you have said already. Mainly I find these issues wax and wane as I heal, time is the answer more than anything. Antibiotics can throw the whole thing off a bit too, so try to avoid anymore if you can. They blitz our gut biome unfortunately and can ramp WD.

I am looking forward to reading more success from you in the coming months

Thanks for stopping by Chippy. I was reading your thread about your own mirt withdrawal. It's such a hard thing to go through and yet you help us all here on the site. Thank you. I wish you continued and fast healing.

Hi @Marie -- I don't have anything to add to what Chippy said about gut symptoms, but I wanted to say congrats again for finishing your taper and I'm so glad to hear that things are going relatively well. The concert sounds amazing, I would love to see CCR!! I'm sure your gut symptoms will improve with time, and I look forward to further updates from you 😊

Thanks Sarah. I am pretty sure it will get better. If this is the only symptom I get in withdrawal I will be happy. It seems a lot of people had nausea tapering mirt. I hardly had nausea tapering, maybe light stuff here and there. This was unexpected so it has thrown me for a loop. I hope you are feeling better these days.

On 9/14/2026 at 7:07 PM, Marie said:

Hello everyone. I just wanted to give an update on my time being off mirt. I've been tapering since 2020. Today it's been over a month and I am doing pretty good. I did have a uti right when I got off with two rounds of antibiotics. I twisted my hip and had to go on prescribed anti-inflammatorys. They all made me sick but I got through it.

Sleep is good, some poorer nights, some good nights, and some magical nights (7/8 hours). I've had a couple fantastic windows. The only thing that is bothering me is my gut. I'm two weeks plus off a/b's. I had been constipated for over a week, gassy, bloaty, and a bit nauseous. I finally figured out to take prunes and they started helping some. Today, however, it changed to loose bowels and more nausea. It's so weird, it's my only withdrawal symptom. Appetite is poor, so I guess I'll lose some weight. Anyone have any suggestions for messed up stomach? How long did it take post taper to stomach issues to resolve?

I had tickets for a concert and I almost cancelled a couple nights ago, Creedence Clearwater Revival and Steve Winwood. OMG I did not expect such a great concert. It was at the beach too so I got a lot of fresh air. I almost cancelled, but I am so glad I went.

If I could just get over the stomach thing I will be golden. Be well. Marie.

Thank you for the update. I'm glad to hear it has not been too bad since coming off.

Yes, nausea and gut symptoms are common when coming off of mirtazapine.

Hopefully they will improve as you said, it's still early days post zero.

Hi Luke, thanks for coming by. Yes the stomach stuff is very common coming off mirt. I am pleased to say after two weeks of this I am in a glorious window. I know it's windows/waves. Hopefully I'll heal quickly. Sleep is more sound and I wake up like a normal person feeling rested. Not much of the cortisol awakenings now. Neck pain is gone and I feel like a real alive normal person. There is no morning fog and the itchiness vanished. These windows are so good that I feel a bit manic. No symptoms.

I went to my doctor to rule things out. I had my blood tested concerning liver, gallbladder and pancreas. Test results were fine. It's funny I said to him that I think it's mirt discontinuation. I know doctors don't like the word withdrawal. I figured I could open up to him now that he is no longer my drug dealer. He agreed with me and explained to me the discontinuation. I played dumb and let him talk. He said the reason I am having stomach issues is because there is a hormone in the gut that's deregulated? I said do you mean receptor and he said it was the same thing. Now I know w/d can last a while but I asked. "So you must have had patients going through this with mirt, what happened with them? How long did it take? Doc told me one to two months. I think he knew it could take longer, but did not want to alarm me. He went on about how it should be tapered slowly. I told him you would be shocked how slow I went. I told him I tapered the last milligram to .01mg. So he has been educated some during the years since I went on mirt in 2014. I remember asking him were there any side effects and was it easy to stop. He told me it might make you a little tired and it's easy to stop. LOL

Hello everyone. Just wanted to stop by and give the details of my recovery. It's been 8 weeks since I've kicked mirt to the curb.

The first month was hard because I had a uti, two rounds of antibiotics, I hurt my right side/hip area, took prescribed strong anti-inflammatory meds, and had reactions to everything. Whew, at least it kept me distracted from any w/d I was having. Sleep was up and down that first month. The next few weeks I just tried to rest and stabilize.

The fifth week I slipped on some wet pavers and went down. I just skimmed my left knee and bruised it (bleeding). Funny, not funny, it was the same knee from the treadmill accident. It was just starting to fade. The new injury is all healed.

At 6/7 weeks I finished my honeymoon period. Some honeymoon! My stomach got painful and bloated, was extremely constipated, and I had some head pressure/nausea. I started getting vertigo for a few days. I was using my hair scrunchie to hold my hair up when I sleep. I remembered previously that when my head was sensitive I would remove it. It caused my head symptoms to get worse. After moving it to the very bottom of my hair to hold it back, it relieved a lot of the head pressure/vertigo. Stomach I took care of by limiting coffee, drinking low fat kefir, and eating less. The low back pain went away too. The constipation I fixed by eating prunes. I think the kefir helped with that also. I am more regular with bowels now. On mirt I would go every 3 days.

Right now I am feeling good. Sleep is a bit better. Even when I don't sleep enough hours, it's still restful. I am getting some really wonderful deep sleep with great hours sometimes. Mood is good, very little fog, very little AM hangover, brain feels like it's working better and clearer, and neck pain gone. My brain still feels sensitive so no alcohol, stressful situations or exercising, I've stabilized but I know I need more time before I start exercising again. At least I was able to lose a lot of weight. It's a good time of year to take it easy and heal. I still have to deal with that major issue in my family. It will probably come to a close by the end of the year. Of course I have to be the one to take care of the situation. At least I've become resilient after all of this and I can handle it.

I'm keeping a positive mindset also because I think it will help me. I have plenty of distractions to use in my toolklit. I think I'll get a jigsaw puzzle, do crosswords, binge some scary Halloween movies, maybe see a show. Waves may come but I'm hopeful I'll heal fairly quick. I'm happy to answer any questions. Be well. Marie.

@Marie This is a wonderful update, congratulations on your progress and being med free! I see the tail end of your mirtazapine taper, but if I can ask, what was your starting dose and how long were you on the medication?

Hi Saturn468. Thanks for stopping by. My dose was 7.5 mg. I was taking mirt since the beginning of 2014.

Hey @Marie Congrats again on completing your taper. So good you are drug free. I can see your first 2 months has not been without it's ups and downs, however it seems like you are moving in a very positive direction. And as always your mindset is on point. I very much look forward to more updates which I think will only get better and beter.

@Marie thanks for the update! I'm sorry to hear you've been dealing with some tough symptoms, but glad to hear you've seen positive progress in a relatively short time. I hope you're right and the remaining healing happens quickly for you. Don't forget to keep us updated as you heal, and to come back and share your success story when the time comes 😊💜

10 hours ago, Chippy said:

Hey @Marie Congrats again on completing your taper. So good you are drug free. I can see your first 2 months has not been without it's ups and downs, however it seems like you are moving in a very positive direction. And as always your mindset is on point. I very much look forward to more updates which I think will only get better and beter.

Thanks Chippy.

6 hours ago, SarahMc said:

@Marie thanks for the update! I'm sorry to hear you've been dealing with some tough symptoms, but glad to hear you've seen positive progress in a relatively short time. I hope you're right and the remaining healing happens quickly for you. Don't forget to keep us updated as you heal, and to come back and share your success story when the time comes 😊💜

Hi Sarah. Yes, I'll stop by every month or two.