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Nickie Evans: Chronic withdrawal from Seroxat

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@Nickie Evans

Click the 3 bars at right top, then Account, then Account Settings, then Notification settings.

 

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol

 

"... your strength will be in keeping calm..."-Isaiah 30:15

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  • Nickie Evans
    Nickie Evans

    @LostinCanada @getofflex @Chippy @Luke dosage was 20mg of Seroxat for almost 30yrs. The generic was Paroxatine at 20mg manufactured by Crescent. Possibly a major breakthrough today, would really like

  • LostinCanada
    LostinCanada

    This is made by GSK. GSK has ceased production and is phasing out supplies. https://assets.publishing.service.gov.uk/media/67bde6b1729cf14d438d76c8/Seroxat_DHPC.pdf   Seroxat is st

  • namastejen1
    namastejen1

    Hi Nickie Evans, welcome to AR! We are here to support you and each other on this Rx journey. I am so sorry you are having the difficulties with the switch to generic. You still are in a good window t

  • Author
3 minutes ago, LostinCanada said:

@Nickie Evans

Click the 3 bars at right top, then Account, then Account Settings, then Notification settings.

 

Thank you @LostinCanada will i start to feel better gradually? I cant bear the thought of being like this for months and.months

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

24 minutes ago, Nickie Evans said:

 will i start to feel better gradually? I cant bear the thought of being like this for months and.months

Reinstating the original drug is more successful. Even then it depends on the individual. Definitely not something any of us signed up for.

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol

 

"... your strength will be in keeping calm..."-Isaiah 30:15

  • Author
8 minutes ago, LostinCanada said:

Reinstating the original drug is more successful. Even then it depends on the individual. Definitely not something any of us signed up for.

@LostinCanadaWhen Dr transferred me from Seroxat to Paroxatine I had adverse effects, this is when it'll started. When you say 'it depends on the individual' what do you mean?? I have to know im going to get past this, I seriously cant live like this indefinitely 

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

2 minutes ago, Nickie Evans said:

depends on the individual

No one can give you a time frame...some stabilize faster than others. The body wants to reach homeostasis. How long that will take, no one knows.

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol

 

"... your strength will be in keeping calm..."-Isaiah 30:15

Hey @Nickie Evans 

 

I am so sorry for all your suffering at the moment.

 

I would certainly not increase the dose anymore.

 

I would start to keep a daily diary with symptoms severity on it rating out of 10, 10 being the worse you could imagine 1 being bareable:

 

Day1 - 5/10

07.00 Woke up

08.00 Took my drug

09.00 Had breakfast

10.00 Got a headache 

And so on.

 

Post it here for safe keeping. It is often good to do this so you can see how things are progressing.

 

Can you update your signature with just your doses to look like this?

 

01 Jan 2025 Seroxat 20mg

11 Nov 2025 Generic Paroxetine 20mg

12 Nov 2026 Generic Paroxetine 0mg

01 Mar 2026 Escitalopram 1mg

07 Mar 2026 Escitalopram 2mg

and so on......

 

Time is your friend.

 

A few things to realise here.

 

The switch caused you some nervous system irritation. Stopping abruptly and being off the drug for a while will have significanlty added to this. RI the orginal drug would have been best, but even then it would have just been offering the brain back a little of what was taken from it in the hopes of making the WD symptoms more bare able. You will have still had some healing to do there for sure.

Adding back a different drug which doesn't effect exactly the same parts of the brain is less likley to help then the orginal drug. So the situation is now a little more complex.

 

Im not sure if adding in Escitalopram has helped or worsened you from what you are saying. It is hard to track this now with the doses being increased so quickly. Perhaps you could rate using the 1/10 system how you were before RI, after, and after each dose increase? It might help us understand if your body is happy on this dose or not.

 

Hopefully it will help in time with the WD symptoms, if your brain is accepting it as a replacement for the paroxetine. The next few weeks will start to tell this.

 

Either way you now unfortunately have a bit of a journey of healing ahead of you.

 

You need time. Time for the dose to take effect and hopfully ease things a little. But mainly time for your body to start to heal all of this, which it will. It isn't an easy process, it is very non linear and happens in windows and waves. But slowly people recover from these injuries and you will too.

 

We are here for you during this process. We all understand it well. You are not alone.

 

Chippy

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • 1 month later...

Hey @Nickie Evans how are you doing?

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author
1 hour ago, Chippy said:

Hey @Nickie Evans how are you doing?

Not good, struggling so badly don't know how much more I can take.

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

22 minutes ago, Nickie Evans said:

Not good, struggling so badly don't know how much more I can take.

I am so very sorry to hear this. Are you still taking 3mg of citalopram?

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author
25 minutes ago, Chippy said:

I am so very sorry to hear this. Are you still taking 3mg of citalopram?

No I went into crisis 7 weeks ago, referred to mental health crisis team and they took me off it, as like you said it wasn't the right substitute med. They put me on mirtazapine (2weeks at 7.5mg and this is week 5 starting on 15mg) i have chronic anxiety, cant sleep (even on 7.5mg it didn't help with sleep) struggling still to eat and this past 10 days i feel as if I've been given speed, the street drug, I don't want to be here anymore, I just cant cope, mental health crisis team are discharging me this week, so have put me on a drug thats i keep saying doesn't suit me and now discharging me. I can't cope i just cant

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

@Nickie Evans im really sorry to read this.

The crisis team can’t help because you don’t have a mental health issue, you are in wd and suffering an injured nervous system. Sadly they only have more drugs as an answer. And they don’t help just make things worse.

As you’ve not been Mirtazapine long and are suffering from being on it, personally id taper off pretty quickly. Longer you are on it, the more dependent you’ll become.

At this point I think being drug free and waiting to heal is your best route.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

Please believe me when I say you will recover from all this. Stay in touch with us, the community is here to help you. Your nervous system and body is amazing and can and will get over this.

We can help you with coping skills and day to day support.

@Nickie Evans

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

I've read online that I could be like this for years and I cant face that, I've effected my daughter with the way I am, shes now got anxiety caused by living with me and seeing me in this mess every day. There seems no end to it and I can't cope with no sleep and constantly feeling wired and mentally hyper.

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

Just now, Nickie Evans said:

I've read online that I could be like this for years and I cant face that, I've effected my daughter with the way I am, shes now got anxiety caused by living with me and seeing me in this mess every day. There seems no end to it and I can't cope with no sleep and constantly feeling wired and mentally hyper.

I can imagine how terrible it must be for your daughter to see you in this situation. Her anxiety is a natural response to the stress of seeing her mum go through this. She hasnt caught it, it’s a human emotion and response, she will be fine, it’s not stuck with her forever. Please make sure she isn’t drugged too. You know only too well what happens when these chemicals are introduced into the situation. Theres lots of content you can both watch, which might help you understand what has happened to you. I can recommend some YouTube channels if you don’t already know of any, and maybe this might help you both better understand what’s happened?

Timelines for recovery are varied. Some heal quicker than others. And of course the suffering lessens over time.

Many have walked this path before you. And as awful as it may seem to you, you can deal with it. You really shouldn’t have to, but you can.

It’s your choice what you do now, you could try to hold and stabilise on Mirtazapine, but from my experience, I’d say it’s doing you more harm being on it and trying to get off swiftly would be for the the best in the long run.

I hate these drugs and what they have done to you. I’m so very sorry, really I am.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

How would i taper off it? The Dr will no doubt say go to 7.5mg for a week and then stop but surely thats too quick of a taper.

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

  • Author
8 minutes ago, Chippy said:

I can imagine how terrible it must be for your daughter to see you in this situation

8 minutes ago, Chippy said:

I can imagine how terrible it must be for your daughter to see you in this situation. Her anxiety is a natural response to the stress of seeing her mum go through this. She hasnt caught it, it’s a human emotion and response, she will be fine, it’s not stuck with her forever. Please make sure she isn’t drugged too. You know only too well what happens when these chemicals are introduced into the situation. Theres lots of content you can both watch, which might help you understand what has happened to you. I can recommend some YouTube channels if you don’t already know of any, and maybe this might help you both better understand what’s happened?

Timelines for recovery are varied. Some heal quicker than others. And of course the suffering lessens over time.

Many have walked this path before you. And as awful as it may seem to you, you can deal with it. You really shouldn’t have to, but you can.

It’s your choice what you do now, you could try to hold and stabilise on Mirtazapine, but from my experience, I’d say it’s doing you more harm being on it and trying to get off swiftly would be for the the best in the long run.

I hate these drugs and what they have done to you. I’m so very sorry, really I am.

. Her anxiety is a natural response to the stress of seeing her mum go through this. She hasnt caught it, it’s a human emotion and response, she will be fine, it’s not stuck with her forever. Please make sure she isn’t drugged too. You know only too well what happens when these chemicals are introduced into the situation. Theres lots of content you can both watch, which might help you understand what has happened to you. I can recommend some YouTube channels if you don’t already know of any, and maybe this might help you both better understand what’s happened?

Timelines for recovery are varied. Some heal quicker than others. And of course the suffering lessens over time.

Many have walked this path before you. And as awful as it may seem to you, you can deal with it. You really shouldn’t have to, but you can.

It’s your choice what you do now, you could try to hold and stabilise on Mirtazapine, but from my experience, I’d say it’s doing you more harm being on it and trying to get off swiftly would be for the the best in the long run.

I hate these drugs and what they have done to you. I’m so very sorry, really I am.

9 minutes ago, Chippy said:

I can imagine how terrible it must be for your daughter to see you in this situation. Her anxiety is a natural response to the stress of seeing her mum go through this. She hasnt caught it, it’s a human emotion and response, she will be fine, it’s not stuck with her forever. Please make sure she isn’t drugged too. You know only too well what happens when these chemicals are introduced into the situation. Theres lots of content you can both watch, which might help you understand what has happened to you. I can recommend some YouTube channels if you don’t already know of any, and maybe this might help you both better understand what’s happened?

Timelines for recovery are varied. Some heal quicker than others. And of course the suffering lessens over time.

Many have walked this path before you. And as awful as it may seem to you, you can deal with it. You really shouldn’t have to, but you can.

It’s your choice what you do now, you could try to hold and stabilise on Mirtazapine, but from my experience, I’d say it’s doing you more harm being on it and trying to get off swiftly would be for the the best in the long run.

I hate these drugs and what they have done to you. I’m so very sorry, really I am.

Yes please can you send me some links to any videos you feel may help. I've had no improvement in 5 months and thought I'd feel slightly better as time went by, but there's no improvement at all.

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

  • Author

You say the suffering lessens over time, but it hasn't and I'm in month 5 now, how long before I do get some slight relief?

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

21 minutes ago, Nickie Evans said:

Yes please can you send me some links to any videos you feel may help. I've had no improvement in 5 months and thought I'd feel slightly better as time went by, but there's no improvement at all.

https://www.youtube.com/@AngiePeacockMSW

https://www.youtube.com/@MedicatingNormal

https://www.youtube.com/@taperclinic

https://www.youtube.com/@outrohealth

These are a few prominent channels to watch. There are many more out there too. Good start points IMO is to watch Angie Peacock, Mark Horowitz & Nicole Lambersons videos. Angies channel is the top one. You will find Mark and Nicole in most if not all of those channels above.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

27 minutes ago, Nickie Evans said:

You say the suffering lessens over time, but it hasn't and I'm in month 5 now, how long before I do get some slight relief?

It does, I will say that in that 5 month period you have had a couple of drugs adding to the mix, IMO this has worsened you, I suspect you can telll that.

If you hold you may stablise on this dose, I am worried it may take a long time and possibly Mirt will worsen you further. I don't know that, I am sharing my thoughts based on my experience and observations of others. This is why I say I would come off Mirt quickly, as I think once you are off it, you can then properly start your healing journey.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author
36 minutes ago, Chippy said:

https://www.youtube.com/@AngiePeacockMSW

https://www.youtube.com/@MedicatingNormal

https://www.youtube.com/@taperclinic

https://www.youtube.com/@outrohealth

These are a few prominent channels to watch. There are many more out there too. Good start points IMO is to watch Angie Peacock, Mark Horowitz & Nicole Lambersons videos. Angies channel is the top one. You will find Mark and Nicole in most if not all of those channels above.

Thank you. How best do I taper off the Mitazapine? I've been 2 weeks at 7.5mg and tomorrow is the start of week 5 at 15mg.

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

30 minutes ago, Nickie Evans said:

Thank you. How best do I taper off the Mitazapine? I've been 2 weeks at 7.5mg and tomorrow is the start of week 5 at 15mg.

You could try reducing doing a linear 25% taper as you’ve not been on long. So go to 11.25mg, then back to 7.5, then 3.25mg then zero.

You’ve been on 6 weeks so you could try to get off in 6 weeks.

Perhaps go to 11.25mg first and see how that goes. One step at a time.

You could taper more slowly and follow the 10% rule but I’d want off quicker than that if it were me and it were possible. Listen to your body it will tell you.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

Dear @Nickie Evans I am so sorry to hear....I think trying to drop that dose of mirt is a good idea but if you get worse after any reduction, I think it is best to hold if necessary.

I know you have been off 5 months but it still might be worth a small reinstatement of paxil/paroxetine at this point... something like 0.1mg-0.5 mg. It is irrelevant at this point what brand you take....it may just be what turns this around for you. It is outside of the preferred 3 months but I have seen it successfully done outside that window of time.

That does not mean it is without risk but if you take it and if within 2 hours feel worse, do not take it again but the possibility is you could feel better.

This is only a suggestion. You have to weigh the risk/benefit. Paroxetine is one of the worst and the healing time is not fast.

Please let me know what you think or if you have any questions. ❤️🙏

Edited by LostinCanada

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol

 

"... your strength will be in keeping calm..."-Isaiah 30:15

10 hours ago, LostinCanada said:

I think it is best to hold if necessary.

Definitely @Nickie Evans

10 hours ago, LostinCanada said:

something like 0.1mg-0.5 mg.

This might be worth a try. Very low. Like 0.1mg. See how you react. If it answers the brains need for Paroxetine it could ease this for you.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Had a call from practitioner this morning went through again about cant sleep and feel hyper and wired all the time. He's speaking with psychiatrist today and said an antipsycotic might be an option 😫 this absolutely terrifies me, i don't want to have that kind of drug. Also mentioned maybe a reinstatement of Paroxatine as an alternative. Advice please @Chippy @LostinCanada

Seroxat from 1996 until its discontinuation December 2025.

 

14/03/26 Dr advising to start Esitalopram 5mg to help with current situation. (Not started, waiting advice from people here first) 

Dr started me on Esitalopram just over 3 weeks ago, starting at 1mg, and increasing weekly by 1mg, currently on 3mg. Depression slightly lifted, horrific cortisol waves upon waking, cant function until up for several hours. Anxiety bad. Chronic diarrhoea.

10 minutes ago, Nickie Evans said:

Had a call from practitioner this morning went through again about cant sleep and feel hyper and wired all the time. He's speaking with psychiatrist today and said an antipsycotic might be an option 😫 this absolutely terrifies me, i don't want to have that kind of drug. Also mentioned maybe a reinstatement of Paroxatine as an alternative. Advice please @Chippy @LostinCanada

I would most certainly not take any more drugs! Wow. It still shocks me doctors do this. Frightening. I shouldnt be shocked. But really wow.

I think considering a very small dose of paroxetine is the only thing I would do. Seroxat if you can get it. But don’t get hung up on getting it if you can’t. Just a generic if needs be. If you can get seroxat just a few boxes will be a start. Each pill is many many doses and we can help you make the most efficient use of the pills so they go a long way.

I’d also try to reduce the Mirt dose by 25% and see how that goes.

Please buy some micro scales. Gem-20 is a good cheap option. There are more expensive options out there too. We can make suggestions but a gem-20 will be fine.

You’ll need this to reduce the mirt and weigh the Paroxetine tablet.

Also you’ll want some needleless syringes. 1ml and 10ml of the same brand would be good.

All the technical stuff we can help you with so don’t worry. You just need those items at a minimum to get started.

If your doctors want you to RI a high dose please don’t do this. I would suggest at this point a tiny dose. You can increase once that dose is established, if required.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

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