Yesterday at 08:29 AM1 day Author Thank you so much for your comments @Chippy very much appreciated xxx 3 weeks Paxil around 2002 I think can’t really remember. CT no issues except for a few head zaps.1 day Citalopram Dec 201710/07/25 - Mirtazapine 7.5mg19/07 - 15mg, 01/08 7.5mg, 15/08 dissolving orodispersible tablets for easier measuring 6mg, 22/08 5mg, 04/09 4mg, 18/09 3mg, 02/10 2.5mg, 16/10 2mg, 30/10 1.5mg, 13/11 1.2mg taper paused due to WD symptoms, had a window 17th March continuous improvement until early June when I went back into a moderate but manageable wave after overdoing things until early July when taking omeprazole for gastritis pushed me into another bad wave. Still waiting to stabilise before proceeding with taper.Supplements - 100mg magnesium glycinate daily.Other meds - Omeprazole 20mg a day when gastritis flares - realised after taking this for 8 days end of June ‘26 I was experiencing some WD symptoms again and researched to find PPIs block the liver enzymes used to metabolise a lot of antidepressants artificially raising blood levels. Stopped omeprazole and 2 weeks later back into a bad wave as my body has reacted as if I’ve updosed and then dropped again.Post menopausal GP has prescribed HRT but have not started as don’t want to confuse my system while tapering.
Yesterday at 01:10 PM1 day The good news is you haven’t been on mirt for years ❣️It took you around 3-4 months to stabilize last time you were holding, right? For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed 2026 (23 July) Mirtazapine 14.79 mg return
Yesterday at 02:59 PM1 day Author Hey @Finni yes 4 months but of course at that point I wasn’t kindled xx 3 weeks Paxil around 2002 I think can’t really remember. CT no issues except for a few head zaps.1 day Citalopram Dec 201710/07/25 - Mirtazapine 7.5mg19/07 - 15mg, 01/08 7.5mg, 15/08 dissolving orodispersible tablets for easier measuring 6mg, 22/08 5mg, 04/09 4mg, 18/09 3mg, 02/10 2.5mg, 16/10 2mg, 30/10 1.5mg, 13/11 1.2mg taper paused due to WD symptoms, had a window 17th March continuous improvement until early June when I went back into a moderate but manageable wave after overdoing things until early July when taking omeprazole for gastritis pushed me into another bad wave. Still waiting to stabilise before proceeding with taper.Supplements - 100mg magnesium glycinate daily.Other meds - Omeprazole 20mg a day when gastritis flares - realised after taking this for 8 days end of June ‘26 I was experiencing some WD symptoms again and researched to find PPIs block the liver enzymes used to metabolise a lot of antidepressants artificially raising blood levels. Stopped omeprazole and 2 weeks later back into a bad wave as my body has reacted as if I’ve updosed and then dropped again.Post menopausal GP has prescribed HRT but have not started as don’t want to confuse my system while tapering.
Yesterday at 03:12 PM1 day 4 minutes ago, Emsy said:Hey @Finni yes 4 months but of course at that point I wasn’t kindled xxI have so much hope for you! I know you can’t see it right now, but this is just a bump in the road. Just hang on 💓 For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed 2026 (23 July) Mirtazapine 14.79 mg return
Yesterday at 03:40 PM1 day Author Oh @Finni bless your heart for taking the time to respond with the intense withdrawal you are going through.My heart goes out to you but I know that one day you’ll finally start to stabilise yourself and we will all be cheering you on.It’s so much easier to see it happening for others than for ourselves for some reason ❤️ 3 weeks Paxil around 2002 I think can’t really remember. CT no issues except for a few head zaps.1 day Citalopram Dec 201710/07/25 - Mirtazapine 7.5mg19/07 - 15mg, 01/08 7.5mg, 15/08 dissolving orodispersible tablets for easier measuring 6mg, 22/08 5mg, 04/09 4mg, 18/09 3mg, 02/10 2.5mg, 16/10 2mg, 30/10 1.5mg, 13/11 1.2mg taper paused due to WD symptoms, had a window 17th March continuous improvement until early June when I went back into a moderate but manageable wave after overdoing things until early July when taking omeprazole for gastritis pushed me into another bad wave. Still waiting to stabilise before proceeding with taper.Supplements - 100mg magnesium glycinate daily.Other meds - Omeprazole 20mg a day when gastritis flares - realised after taking this for 8 days end of June ‘26 I was experiencing some WD symptoms again and researched to find PPIs block the liver enzymes used to metabolise a lot of antidepressants artificially raising blood levels. Stopped omeprazole and 2 weeks later back into a bad wave as my body has reacted as if I’ve updosed and then dropped again.Post menopausal GP has prescribed HRT but have not started as don’t want to confuse my system while tapering.
Yesterday at 03:56 PM1 day 14 minutes ago, Emsy said:Oh @Finni bless your heart for taking the time to respond with the intense withdrawal you are going through.My heart goes out to you but I know that one day you’ll finally start to stabilise yourself and we will all be cheering you on.It’s so much easier to see it happening for others than for ourselves for some reason ❤️It’s so sad because I think I might have been starting to stabilize. I was shopping online, doing more around the house, laughing, interested in birds again… Now mirt seems to be so reactive that I’m not sure I can keep holding. For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg (.1026 g)2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late2026 (22 July) Mirtazapine 14.76 mgIntense electric activation, muscle tightness, autonomic surges, terror followed 2026 (23 July) Mirtazapine 14.79 mg return
23 hours ago23 hr Author @Finni your nervous system has had so many ups and downs.As others have said, I really think if you stop trying to dose your way out it will eventually start to settle again but I know how hard things are for you right now and waiting to stabilise must feel so so hard ❤️ 3 weeks Paxil around 2002 I think can’t really remember. CT no issues except for a few head zaps.1 day Citalopram Dec 201710/07/25 - Mirtazapine 7.5mg19/07 - 15mg, 01/08 7.5mg, 15/08 dissolving orodispersible tablets for easier measuring 6mg, 22/08 5mg, 04/09 4mg, 18/09 3mg, 02/10 2.5mg, 16/10 2mg, 30/10 1.5mg, 13/11 1.2mg taper paused due to WD symptoms, had a window 17th March continuous improvement until early June when I went back into a moderate but manageable wave after overdoing things until early July when taking omeprazole for gastritis pushed me into another bad wave. Still waiting to stabilise before proceeding with taper.Supplements - 100mg magnesium glycinate daily.Other meds - Omeprazole 20mg a day when gastritis flares - realised after taking this for 8 days end of June ‘26 I was experiencing some WD symptoms again and researched to find PPIs block the liver enzymes used to metabolise a lot of antidepressants artificially raising blood levels. Stopped omeprazole and 2 weeks later back into a bad wave as my body has reacted as if I’ve updosed and then dropped again.Post menopausal GP has prescribed HRT but have not started as don’t want to confuse my system while tapering.
21 hours ago21 hr Hi @Emsy. I’ve just read through your page and I’m so sorry for what you’re going through😞. I can resonate with your omeprazole interaction because that’s what happened to me last year. When I first went into WD I was taking 20mg omeprazole alongside my lexapro(not knowing of the interaction). I stopped the omeprazole for 5 days prior to to an endoscopy. Of course after 3-4 days I went further into WD then back up to my normal dose once it settled againThen I switched brands a month lasted which of course threw me off again. What a mess. Anyway I decided to stick with the omeprazole, not for stomach acid suppression but for stability.Wishing you all the best Lexapro: Aug 2023 – Lexapro 5mg Jan 2024 – Lexapro 20mg Jun 2024 – Lexapro 17.5mg (Kept tapering down in 2.5mg increments till Aug) Aug 2024 – Lexapro 2.5mg (Withdrawal hit after stopping 2.5mg) Oct 2024 – Lexapro 5mg Jan 2025 – Lexapro 1mg, 1.25mg, 1.5mg, 2mg (Drs orders back reaction) Feb 2025 – Lexapro 1.5mg Sept 2025 – Stabilized Dec 2025 – Back in WD Omeprazole: ?? June 2024 – 20mg 08 Mar 2025 – Stopped 14 Mar 2025 – 20mg 05 April 2025 – Brand swap Start Sept - 15mg (2 week taper) End Sept 2025 - 10mg (By end of Sept) 05 Feb 2026 – Brand swap Supplements: Fish Oil - AM High DHA & EPA Loratadine Am Magnesium Glycinate pm 1,000mg
20 hours ago20 hr Author @Johan1233 thank you so much for taking the time to share your experience.I hadn’t needed omeprazole for 6 months so when I started it again beginning of July I could feel the mirtazapine levels rising in my system as I started to feel dizzy and much more sedated.It’s really messed me about and honestly if id known about the issue at the beginning of my taper id have probably stayed on it and not come off for 6 months but I didn’t know any better!Hindsight and all that.Sorry to read you are in WD.Are you still holding the Lexapro at 1.5mg? 3 weeks Paxil around 2002 I think can’t really remember. CT no issues except for a few head zaps.1 day Citalopram Dec 201710/07/25 - Mirtazapine 7.5mg19/07 - 15mg, 01/08 7.5mg, 15/08 dissolving orodispersible tablets for easier measuring 6mg, 22/08 5mg, 04/09 4mg, 18/09 3mg, 02/10 2.5mg, 16/10 2mg, 30/10 1.5mg, 13/11 1.2mg taper paused due to WD symptoms, had a window 17th March continuous improvement until early June when I went back into a moderate but manageable wave after overdoing things until early July when taking omeprazole for gastritis pushed me into another bad wave. Still waiting to stabilise before proceeding with taper.Supplements - 100mg magnesium glycinate daily.Other meds - Omeprazole 20mg a day when gastritis flares - realised after taking this for 8 days end of June ‘26 I was experiencing some WD symptoms again and researched to find PPIs block the liver enzymes used to metabolise a lot of antidepressants artificially raising blood levels. Stopped omeprazole and 2 weeks later back into a bad wave as my body has reacted as if I’ve updosed and then dropped again.Post menopausal GP has prescribed HRT but have not started as don’t want to confuse my system while tapering.
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