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Skamen: Anhedonia caused by 14 years of Paxil, now in hell after CT

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  • Author

... and one year before the CT in dark anhedonia caused by the drug and ON many drugs, dear @Nemina. February 2024 I crashed, my brain refused to function. Two years and 7 months in dark Hell...

Svetla

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

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  • Dear @Nemina, I am in the deepest of my suffering, nothing helps, I don't know how I will survive...

  • Pokey449
    Pokey449

    @skamen I’m not doing very well today. WD symptoms keep coming back. Another terrible night again last night. And I’m all alone. The loneliness really closes in on me , especially at night when I jo

  • @skamen Two years and seven months, that is an incredible long time for such terrible suffering. I’m so proud of you that you keepl fighting. Do not give up my friend! We will celebrate your healing t

Posted Images

@skamen Two years and seven months, that is an incredible long time for such terrible suffering. I’m so proud of you that you keepl fighting. Do not give up my friend! We will celebrate your healing together on this forum one day. I found a success story, that might encourage you, I thought of you while reading it:

https://www.survivingantidepressants.org/forums/topic/22421-happilyderailed-from-heaven-to-hell-and-back/

Take care, my dear, you are in my thoughts and prayers ❤️

SA Thread: https://www.survivingantidepressants.org/forums/topic/33406-nemina-tapering-escitalopram/


AR Thread: https://antidepressantrecovery.org/topic/14-nemina-tapering-escilatopram-and-zolpidem/

 

Drug History

2013 - 2025:  Zolpidem 5 mg

2015 - Oct 2024: Venlafaxine, Sertralin (Zoloft), Paroxetin (Paxil),duloxtin (cymbalta), Citalopram (Celexa), Escitalopram (Lexapro) and more 

 

Current Drugs

L-Thyroxin 75, Estrogen, Progesteron 200

 

Tapering Escitalopram

Until Sept 2024: Setralin/zoloft 75 mg

Oct 2024: Switch to Escitalopram / Lexapro 2mg

Then I tapered over a year from 2mg to 0,32 mg (October 2025).  108 days hold without stabilizing. Resumed taper February 2026:

11 Feb 2026 0.314mg 

18 Feb 2026 0.307mg 

21 Feb 2026 0.302mg

09 Mar 2026 0.297mg

18 April 2026 0,293 mg

18 May 2026 0,285 mg

18 June 2026 0,265 mg

18 July 2026 0,250 mg

18 Aug 2026 0,232 mg

18 Sept 2026 0,232 mg (Holding since 19.8.)

 

Tapering Zolpidem: From 5 mg to 0,7 mg in 12 months,  then just crumbs for several weeks, now 0! (Jan 2026)

 

Other Supplements 

Omega 3, Magnesium Glycinate, Vit D, Calcium, L-theanin, Vit C, Vit K2, Selen

  • Author

Thank you, sweet @Nemina. This incredibly long story gives me a hope. Our endless suffering is inhumane.

Svetla

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

On 9/18/2026 at 3:47 PM, skamen said:

... and one year before the CT in dark anhedonia caused by the drug and ON many drugs, dear @Nemina. February 2024 I crashed, my brain refused to function. Two years and 7 months in dark Hell...

Svetla

Wow ...keep fighting. I'm only 22 months on this journey and I'm thinking to hold little longer before resuming tapering again....my mornings are the bad part of the day, then, it gets better as time passes by ..

08/01/2009- Klonopin 1mg, but took only .25mg when needed, and end up taking every day for 3 years. 08/01/2012 - Paraxotine 20 mg

12/2024- reinstated 5mg (.0740g)after cold turkey. First tapering 07/01/2025 = 1.2% , 09/01/2025 - another 1.4%. 10/01/2025- 4.79mg (.0716g) holding until further notice........04/17/26 resumed taper 0714g (4.78mg). 05/20/2026- .0712g (4.76mg, .28% cut). 06/09/2026- .0708g (4.73mg .56% cut). 06/30/2026 - .0706g (4.72mg .33%). 07/28/2026 - .0700g (4.68mg, .85%).09/01/26 - .0698g (4.66mg, .29%).

@skamen have you been taking the vitamin C or magnesium regularly?

If so what dose? Thanks. ❤️🙏

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol

 

"... your strength will be in keeping calm..."-Isaiah 30:15

  • Author

Dear @LostinCanada , thank you for your message. I don't take any supplements, I am fo scared to do the unbearable situation worse. I have taken vitamin C, 500 mg, and my sleep got worse... I suppose that my CNS is incredibly sensitized. What a suffering with insomnia, hot flashes, awful cortisol, doom and constant feeling of terror. No one minute of window since the CT in March 2025... And the horror became hellish when I stopped the last antidepressant, Mirtazipine, March 20,2026. Thank you to be here, @LostinCanada.

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

22 minutes ago, skamen said:

Dear @LostinCanada , thank you for your message. I don't take any supplements, I am fo scared to do the unbearable situation worse. I have taken vitamin C, 500 mg, and my sleep got worse... I suppose that my CNS is incredibly sensitized. What a suffering with insomnia, hot flashes, awful cortisol, doom and constant feeling of terror. No one minute of window since the CT in March 2025... And the horror became hellish when I stopped the last antidepressant, Mirtazipine, March 20,2026. Thank you to be here, @LostinCanada.

Sorry the Vit C didn't help. Minute by minute.... sending hugs.❤️🙏

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg/Sep 18-3.8mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for reflux/150 mg calcium citrate/algae oil for omega 3/ginger as needed for nausea/500 mg of Vitamin C for cortisol

 

"... your strength will be in keeping calm..."-Isaiah 30:15

@skamen Hi Svetla. How are you doing? I don’t know how you do it with as little sleep as you get. Some nights I get 6hrs but then last night I only got 3. In doing so I woke up 6 times per my smart watch. And I’m exhausted. I wake up with terrible sxs. Feel like I’m going to die. Don’t know what’s going on. Cortisol maybe, but doesn’t feel like it exactly. But I know you get cortisol spikes all night long. Again I don’t know how you do it. I’m pretty much exhausted all the time.

Anyway I do hope you are getting some relief. Lord knows you deserve some good rest. Take care

Pokey.

Pokeys Topic

Pokeys Archived Dose History

Current Medication:

2.5mg of nebivolol for BP

5mg Eliquis x2.

Vitamin D, 40mg Famotidine PRN

Magnesium glycinate ,5mg melatonin

20 March 2025 - Mirtazapine - 7.5mg (+41.5%)

20 Feb 2026 - Doxepin 29.6mg (0.6mg updose)

  • Author

Dear @Pokey449, I read regularly your posts, and I am so sorry for your familial worries. I hope a peace for your mind soon.

My sleep is horrendous, I cannot sleep literally, some nights 0 sleep, some nights 3-4 hours broken sleep. I wake up every 90 minutes in sweats and terror. And around 5 a.m. the cortisol becomes awful, I cannot stay in bed because of the sensation of dying. I am month 18 after CT and month 7 after the last pill of Mirtazapine. No window at all until now. This is not a life, it is a true torture in constant depression, anhedonia, anxiety. As you, I am exhausted but in restlessness.... A real Hell. But do we have a solution, Pokey? We have to hope in Time.

Svetla

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

@skamen Hi Svetla I am very very sorry to see you still suffering the HORENDOUS living hell these torture drugs put

us through. I am afraid it's bad news from me Svetla, I just could not take it anymore, 4 hours and less sleep for 19 months

sent me into a choice.....death or RI.....zero money coming in, which may have been slightly rectified by DWP....not sure yet.

But I needed to get some sleep back. So 1.87mg at first and sleep was rectified, stomach issues gone as well. That was mid Aug

and I have lifted to about 4.37mg now. Sleeping 7 hours broken, Still zero motivation, but am getting more rest, still up and

down days, but the bad ones no where near as horrendous.

I have always been here in the shadows Svetla, and have never missed a day. We both know SOME are hit harder than others,

our genetic makeup playing that part, so it's easy to see the ones deeper affected. Don't let my RI put you off in any way, we

are ALL different, right or WRONG I just did myself what I thought I had to do. PART of me, a little part is regretting my move,

but truly I was worse at 19 months off than at 3 months off.

So keep plodding Svetla and stay safe, I will just keep going as best I can, I will keep it going until it get's better or worse, I

will just hope for the best with it.....but non living is the pits.....I was just so sick and tired of it. Maybe I was only a month

or 2 off being recovered.....who knows....but I was just a zombie like that....so it's onwards I plod WHATEVER.

Take great care, B.

2001-2021 Prozac 20mg

2020-2021 Tramadol 300mg

2022 April 15th  Started Mirtazapine 15mg

2022 Sept 15 dropped to 7.5mg

2023 May 16th failed CT reinstated.

2023  June 30th tapering off

2025 Jan 7th Stopped all drugs.

  • Author

Dear B., I am glad that you are back in this site. Thank you for your message. You did what it was the best for you. At least you can get some sleep now.

I am in my month 18 after CT and month 7 after stopping the last antidepressant, the hellish Mirtazapine. As you, my situation goes worse, night sweats and feeling of dying, a pure terror. And around 5 a.m.the hellish cortisol kills me. I have around 4-5 hours broken sleep. The day the depression and the anhedonia are unbearable, a Hell. We continue to support each other, dear B.

Svetla

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

2 hours ago, skamen said:

We continue to support each other, dear B.

Svetla

@skamen Thanks Svetla, just heart breaking to see you in such devastating torture. Thanks for understanding, all

I am doing for now.....is just trying to stay alive. Beyond belief how these drugs can torture the mind, to instil a FEAR

unbeknown to mankind. Tears, pain, heartache, insomnia and an anxiety beyond comprehension. Big pharma have one

hell of a lot to answer to. How these drugs have ever been passed for human treatment is beyond me. Keep plodding

Svetla, stay safe, keep strong and god bless, B.

2001-2021 Prozac 20mg

2020-2021 Tramadol 300mg

2022 April 15th  Started Mirtazapine 15mg

2022 Sept 15 dropped to 7.5mg

2023 May 16th failed CT reinstated.

2023  June 30th tapering off

2025 Jan 7th Stopped all drugs.

Hang in there @skamen… I am so proud of you. You are so strong ❤️‍🩹❤️. True warrior! ❤️

12 august 2025; 5mg fluoxetine 

30 August 2025: 10mg fluoxetine 

11 september 2025: 5mg fluoxetine 

19 september 2025; 2.5mg fluoxetine 

2 oktober 2025: 0mg

 

I had to cut my pills in half and quarters, so and don’t think I had accurate dosages.

  • Author

Thank you, @Sophia. What an awful journey for everyone of us. I feel you very well, the anhedonia is unbearable, it takes from us every humane thing.

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

@skamen Svetla. I’m still trying to figure out what’s happening in my sleep that’s waking me up feeling awful. I wake up in pain, very groggy, heart rate is up. So is my BP if I take it. I’m semi-dizzy, headache often. I feel stressed. The Term I use is “brittle”. I lay there a while, deep breathe, sometimes get up, go back to bed. I Stretch, self massage. The symptoms wear off. I go back to sleep only to wake up later with same symptoms all over again I think it’s due to cortisol. Only thing I can think of. Do you have similar symptoms?

Pokey

Pokeys Topic

Pokeys Archived Dose History

Current Medication:

2.5mg of nebivolol for BP

5mg Eliquis x2.

Vitamin D, 40mg Famotidine PRN

Magnesium glycinate ,5mg melatonin

20 March 2025 - Mirtazapine - 7.5mg (+41.5%)

20 Feb 2026 - Doxepin 29.6mg (0.6mg updose)

Just dropping by to give you a hug, you strong and brave woman. Take care, @skamen , your day will come.

SA Thread: https://www.survivingantidepressants.org/forums/topic/33406-nemina-tapering-escitalopram/


AR Thread: https://antidepressantrecovery.org/topic/14-nemina-tapering-escilatopram-and-zolpidem/

 

Drug History

2013 - 2025:  Zolpidem 5 mg

2015 - Oct 2024: Venlafaxine, Sertralin (Zoloft), Paroxetin (Paxil),duloxtin (cymbalta), Citalopram (Celexa), Escitalopram (Lexapro) and more 

 

Current Drugs

L-Thyroxin 75, Estrogen, Progesteron 200

 

Tapering Escitalopram

Until Sept 2024: Setralin/zoloft 75 mg

Oct 2024: Switch to Escitalopram / Lexapro 2mg

Then I tapered over a year from 2mg to 0,32 mg (October 2025).  108 days hold without stabilizing. Resumed taper February 2026:

11 Feb 2026 0.314mg 

18 Feb 2026 0.307mg 

21 Feb 2026 0.302mg

09 Mar 2026 0.297mg

18 April 2026 0,293 mg

18 May 2026 0,285 mg

18 June 2026 0,265 mg

18 July 2026 0,250 mg

18 Aug 2026 0,232 mg

18 Sept 2026 0,232 mg (Holding since 19.8.)

 

Tapering Zolpidem: From 5 mg to 0,7 mg in 12 months,  then just crumbs for several weeks, now 0! (Jan 2026)

 

Other Supplements 

Omega 3, Magnesium Glycinate, Vit D, Calcium, L-theanin, Vit C, Vit K2, Selen

  • Author

Yes, @Pokey449, for me it is the cortisol triggered by the anxiety. I have also an awful nausea and hot flashes, heart rate up. Last night I had only one hour sleep, from 4 to 5 a.m. This lack of sleep will kill us.

Svetla

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

@skamen Svetla I hear you about the lack of sleep. I have days I wake up wondering what is keeping me alive I feel so bad. I can fall asleep ok but can’t stay asleep. I keep waking up with th horrid symptoms I described above. It’s hell on earth. And I’ve been at the same dose for 200+ days but I have a lot of stress in my life currently. I hope you can get some semblance of sleep/rest soon.

Pokeys Topic

Pokeys Archived Dose History

Current Medication:

2.5mg of nebivolol for BP

5mg Eliquis x2.

Vitamin D, 40mg Famotidine PRN

Magnesium glycinate ,5mg melatonin

20 March 2025 - Mirtazapine - 7.5mg (+41.5%)

20 Feb 2026 - Doxepin 29.6mg (0.6mg updose)

  • 2 weeks later...
On 10/2/2026 at 9:55 PM, skamen said:

Yes, @Pokey449, for me it is the cortisol triggered by the anxiety. I have also an awful nausea and hot flashes, heart rate up. Last night I had only one hour sleep, from 4 to 5 a.m. This lack of sleep will kill us.

Svetla

I am so sorry that your suffering is still going on. I keep praying for you, dear @skamen .

SA Thread: https://www.survivingantidepressants.org/forums/topic/33406-nemina-tapering-escitalopram/


AR Thread: https://antidepressantrecovery.org/topic/14-nemina-tapering-escilatopram-and-zolpidem/

 

Drug History

2013 - 2025:  Zolpidem 5 mg

2015 - Oct 2024: Venlafaxine, Sertralin (Zoloft), Paroxetin (Paxil),duloxtin (cymbalta), Citalopram (Celexa), Escitalopram (Lexapro) and more 

 

Current Drugs

L-Thyroxin 75, Estrogen, Progesteron 200

 

Tapering Escitalopram

Until Sept 2024: Setralin/zoloft 75 mg

Oct 2024: Switch to Escitalopram / Lexapro 2mg

Then I tapered over a year from 2mg to 0,32 mg (October 2025).  108 days hold without stabilizing. Resumed taper February 2026:

11 Feb 2026 0.314mg 

18 Feb 2026 0.307mg 

21 Feb 2026 0.302mg

09 Mar 2026 0.297mg

18 April 2026 0,293 mg

18 May 2026 0,285 mg

18 June 2026 0,265 mg

18 July 2026 0,250 mg

18 Aug 2026 0,232 mg

18 Sept 2026 0,232 mg (Holding since 19.8.)

 

Tapering Zolpidem: From 5 mg to 0,7 mg in 12 months,  then just crumbs for several weeks, now 0! (Jan 2026)

 

Other Supplements 

Omega 3, Magnesium Glycinate, Vit D, Calcium, L-theanin, Vit C, Vit K2, Selen

On 10/2/2026 at 9:55 PM, skamen said:

Yes, @Pokey449, for me it is the cortisol triggered by the anxiety. I have also an awful nausea and hot flashes, heart rate up. Last night I had only one hour sleep, from 4 to 5 a.m. This lack of sleep will kill us.

Hi dear , do you have some windows sometimes? I hope they will there soon with you dear Svetla❤️

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (gaining wait, vertigo, low mood)

12-2025 quit oxazepam

04-2026 because of major brain zap RI 25mg one week, up to 50mg next week and get depressed and quit. This was a high dose.

I also started oxazepam again

17-Mei 2026 RI 10 mg 3 days and 5mg 2 days in the hospital.

21-5 CT Sertraline

I felt better after 5 days and then crashed

27-6 quit oxazepam

Symptoms:

Depression, anhedonia, DPDR

Reinstatement Zoloft 2026

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

3-9 RI Zoloft 3mg

I always take magnesium and fish oil

  • Author

Dear @Saar8srl, thank you to contact me. I follow every your post and know that you struggle bad also.

I don't know how I will survive. I am at the end of my month 7 of real Hell: hot flashes exclusively at night + adrenaline waves of terror, insomnia, terrible depression, utter anhedonia. I am not functional... No window, no light.

And what about you?

Svetla

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

I’m actually curious why some of you still experience core PWD symptoms even before coming fully off medication. Is it because the current dosage is no longer sufficient to suppress symptoms?

I am now 15 months fully off my medication. Early‑morning awakening between 3 a.m. and 4 a.m. still plagues me, accompanied by sharp emotional crashes. While the intensity has decreased considerably compared to three months ago, I still go through these mood swings every single day.

I have gone through a lot of materials. The underlying mechanisms involve abnormally elevated cortisol, glutamate buildup, and insufficient GABA inhibition. Time is the only remedy to recalibrate HPA‑axis rhythms. Hope everyone gets better!

2020–Early 2025: Sertraline titrated 50mg→200mg daily. One-month trial of Escitalopram. Rotated bedtime sedatives (Alprazolam, Estazolam, Lorazepam), finally Olanzapine, tapered off after ~1–2 years.

Jan 2025 – July 31 2025: Slow sertraline taper, minus 50mg every 1–2 months; temporary 25mg dose boost for symptom stabilization. Fully withdrawn 31 July 2025.

Mar 2026 – Jun 2026: TCM herbal therapy, later discontinued.

Jun 2026 – Present: Inositol 4g, NAC 1500mg, Magnesium Glycinate 250mg, Magnesium L-Threonate 36mg, Fish Oil 1000mg, PS 150mg, L-Theanine 600mg, Zinc Gluconate 10mg

11 hours ago, skamen said:

And what about you?

Dear Svetla,

That’s warms my heart that you follow my threads. ❤️I’m not good. Severe depression, DPDR or totally numb. Don’t feel human anymore. Sometimes I experience a window and I can breath somehow but they are not many. I’m glad if the evening is lighter but also that doesn’t happen a lot . I hope you will have your first relief soon. Tell me if the windows come , I will celebrate it with you. I have the feeling you have heart of gold❤️you deserve all the happiness and joy in the world. Let your loved ones take care of you sweet Svetla ❤️❤️

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (gaining wait, vertigo, low mood)

12-2025 quit oxazepam

04-2026 because of major brain zap RI 25mg one week, up to 50mg next week and get depressed and quit. This was a high dose.

I also started oxazepam again

17-Mei 2026 RI 10 mg 3 days and 5mg 2 days in the hospital.

21-5 CT Sertraline

I felt better after 5 days and then crashed

27-6 quit oxazepam

Symptoms:

Depression, anhedonia, DPDR

Reinstatement Zoloft 2026

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

3-9 RI Zoloft 3mg

I always take magnesium and fish oil

  • Author

The psychiatrist prescribed me today gabapentin 100 mg 1st week, 200 mg 2nd week and 300 mg 3th week. I am so scared to take something with my hypersensitized NS. I have been 7 months without anything, nor antidepressants neither supplements. My WD symptoms are awful: inner akathisia, hot flashes + terror at night, brain fog, depression, anhedonia. I never experienced a window until now, straight suffer and agony. Any advices about this? Thank you.

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

13 minutes ago, skamen said:

The psychiatrist prescribed me today gabapentin 100 mg 1st week, 200 mg 2nd week and 300 mg 3th week. I am so scared to take something with my hypersensitized NS. I have been 7 months without anything, nor antidepressants neither supplements. My WD symptoms are awful: inner akathisia, hot flashes + terror at night, brain fog, depression, anhedonia. I never experienced a window until now, straight suffer and agony. Any advices about this? Thank you.

I would not take it. Just from being in the akathisia groups, I've seen that gabapentinoids are not guaranteed to help. For multiple people, they suppressed the aka for like a few weeks and then stopped working and then they still had their symptoms plus another drug to taper off of.

I understand your agony. But you seem to have come so far and are off the drugs. I do believe you will improve in time.

2011-2012: Lexapro 5mg, then rapid taper. Delayed WD but didn't realize the connection at the time

Apr 2018: Lexapro 5mg

2018: Lexapro 2.5mg. Failed attempts to reduce further over the years by halving dose, skipping doses

Jul 29 2025: Monoferric 1000mg iron infusion

Aug 2 2025: Severe akathisia, WD begins

Aug 11 2025: Lexapro CT

Aug 26 2025: Lexapro 1.06mg reinstatement

Dec 1 2025: Began using scale to weigh Lexapro dose

Jul 2026: Increased iron-rich foods in diet

Aug 9 2026: Further destabilization, interdose WD begins

Supplements: Magnesium 150mg, Melatonin 1mg, Lemon balm tea x 2

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