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Richie: Mirtazapine withdrawal stressed

Featured Replies

15 hours ago, LostinCanada said:

I will answer your pm here.

Usually poop out occurs if you have been on a drug for a long time...the body just builds up a tolerance to it.

It seems like you are dealing with fall out from your cold turkey and overdose.

Depression is a side effect from these drugs as well as a withdrawal symptom....the very thing they are supposed to prevent, they can cause.

It takes months to stabilize after what you have experienced. Time, patience and acceptance is important. 

Are you able to practice CBT? It can help with the anxiety and ruminating thoughts. It is important to tell yourself you are safe, your body wants homeostasis....do all you can to create an environment for healing. ❤️🙏

 

Thank you lic, well said. Poop out is something that concerns many but I think for most its just that.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

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  • Another day of goodness, woke up good had about 9 hours sleep got ready went to the gym, Mrs went shopping, made dinner all in another good day hopefully more to come. i wish everyone struggling

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    Woke up about 10 abit spaced out went out with the Mrs and just like that boof everything gone completely normally anhedonia gone mood as high as anything. Complete doplamine rush all day. I feel love

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13 hours ago, Richie said:

Thank you so much @LostinCanada

 

i will try the CBT.

 

Im just scared as when I originally reinstated the 3.75mg I felt a lot better for a few weeks went down in dose to 2.5mg (too big of a drop) stayed there for 4 weeks to try stabilise which I didn’t so went back up to 3.75mg only had two days of relief and now stuck in this rut. Going down brought on more symptoms of high heart rate insomnia (gotten better) and anxiety 

 

thanks for your reply I appreciate your time. 

I hear you mate. We are all here for you. Unfortunately this kind of disruption is upsetting for the nervous system. It can take a long time to settle and happens in waves and windows.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

On 2/8/2026 at 3:03 PM, Richie said:

tried to prescribe me Seroquel

Hi @Richie - Good to meet you mate, albeit in trying circumstances. 
 

I’ve read your story, I’m also in a tough spot with Mirtazapine myself.. only took it for a month and then had horrible WDs and like you, had horrible side effects when I first started it. Lucky that you managed to avoid quetiapine, I unfortunately paid a private psychiatrist to help me and he would not give up in trying to prescribe it. When I had my last crash after trying to withdraw, I finally took it because of the panic and terror I was experiencing, stuff left me absolutely in despair and wanting to end it at every corner I looked, it was horrible. I immediately stopped and never took it again, I had some horrible thoughts one week after that crash too but thankfully they went away. 
 

Me and my wife have just had a first kid together so I know how difficult this is with having children in the mix too. You’re not alone mate, I’ve only just started my journey too and had to reinstate from my last crash, I’m still stabilising but it does get better. Hopefully you and I can support each other on the way down. 

Drug History:

Dec 2th - 3rd: Sertraline; 25mg x2 doses - ADR: Severe akathisia for 48hrs, hospitalised.

Dec 4th - 11th: Mirtazapine; 15mg; Severe side effects

Dec 11th - 1st Jan: Mirtazapine; 7.5mg

Failed fast taper as per GP's & Psych's advice of 7.5mg -> 5.25mg -> 3.75mg over 2 weeks, severe withdrawals, 3 days after last dose.

Jan 14th - 15th: Quetiapine; 25mg x2 doses - ADR: Severe SI & Depression.

On/Off Lorazepam & Diazepam use during entire ordeal.

Jan 14th: Mirtazapine; 5.25mg reinstated - Currently waiting to stabilise.

July 13th: 4.95mg

Aug 28th: 4.80mg

 

Current symptoms: Anhedonia, DR, Anxiety, Depression, OCD, Cognitive impairment, Extreme fatigue, Nausea, Migraines.

 

  • Author

Hi @The_Taper_Man good to meet you to bud, our story’s are very similar never in my life would I have thought this drug could cause all these problems. Along with the nhs being so oblivious to all this aswell. If you wanna exchange numbers to talk mate send me a dm would defo like to hear more about your symptoms and story.

 

kind regards 

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

55 minutes ago, Richie said:

never in my life would I have thought this drug could cause all these problems.

Me neither mate @Richie, I was heartbroken about all of it when I was going thru it. Feel free to read up on my post and story to get the details, it took me forever to get my family to come around with what was going on... That hurt the most.

 

56 minutes ago, Richie said:

If you wanna exchange numbers to talk mate

Yes! 100% - I am always up for supporting each other and making sure we've got each other's backs in this, Lord knows it looks like we're going to need it man. I've DM'd you.

Drug History:

Dec 2th - 3rd: Sertraline; 25mg x2 doses - ADR: Severe akathisia for 48hrs, hospitalised.

Dec 4th - 11th: Mirtazapine; 15mg; Severe side effects

Dec 11th - 1st Jan: Mirtazapine; 7.5mg

Failed fast taper as per GP's & Psych's advice of 7.5mg -> 5.25mg -> 3.75mg over 2 weeks, severe withdrawals, 3 days after last dose.

Jan 14th - 15th: Quetiapine; 25mg x2 doses - ADR: Severe SI & Depression.

On/Off Lorazepam & Diazepam use during entire ordeal.

Jan 14th: Mirtazapine; 5.25mg reinstated - Currently waiting to stabilise.

July 13th: 4.95mg

Aug 28th: 4.80mg

 

Current symptoms: Anhedonia, DR, Anxiety, Depression, OCD, Cognitive impairment, Extreme fatigue, Nausea, Migraines.

 

  • Author

Had quite a flat day yesterday awoke with the usual doom, by about 10 at night seemed to perk up and feel pretty normal, obv the sleep reset kicks in and woke up to the normal crap. Plodding along hoping for an extended window. Ordered myself the A&D EJ-54D2 Compact Balance (22/52g x 0.0002/0.001g) scale hoping for more precise weighing. 450 quid later hopefully this works lol.

 

 

Edited by Richie

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

@Richie Rooting for you bro. Hang in there 

Exact dates are ballpark estimates. 

 

Current medications: None

 

1 Oct. 2024 - Lexapro 10mg

1 Jan. 2025 - Lexapro 15mg

1 Feb. 2025 - Lexapro 20mg 

5 Feb. 2025 - Lexapro 15mg

 

Taper: 

July 2025 - went from 15mg to 10 to 5, to 5 every other day and then 0 over the course of roughly 2 weeks.

 

About 3ish weeks after hitting 0mg - I crashed - like a switch flipped in my brain.

@Richie Rooting for you bro. Hang in there 

Exact dates are ballpark estimates. 

 

Current medications: None

 

1 Oct. 2024 - Lexapro 10mg

1 Jan. 2025 - Lexapro 15mg

1 Feb. 2025 - Lexapro 20mg 

5 Feb. 2025 - Lexapro 15mg

 

Taper: 

July 2025 - went from 15mg to 10 to 5, to 5 every other day and then 0 over the course of roughly 2 weeks.

 

About 3ish weeks after hitting 0mg - I crashed - like a switch flipped in my brain.

On 2/11/2026 at 4:45 AM, Richie said:

Ordered myself the A&D EJ-54D2 Compact Balance (22/52g x 0.0002/0.001g) scale hoping for more precise weighing. 450 quid later hopefully this works lol.

Awesome…mine is still going strong after 3 years….it makes me much more confident with my doses. 
One day at a time….always remember this isn’t the real you…it’s these rotten drugs….we will heal. 🙏❤️

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for refux/150 mg calcium citrate/algae oil for omega 3/ginger 400 mg as needed for nausea

 

"... your strength will be in keeping calm..."-Isaiah 30:15

  • Author

This journey is so hard 😢 

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

24 minutes ago, Richie said:

This journey is so hard 😢 

I’m sorry Richie. We’re here mate. 

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Thank god my mood has lifted abit. What a rollercoaster this is….

 

Edited by Richie

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

2 minutes ago, Richie said:

Thank god my mood has lifted abit. What a rollercoaster this is….

 

This is great.  Tell me about...these changes are crazy.  

 

It will get better too ..

 

You doing great ..

08/01/2009- Klonopin 1mg, but took only .25mg when needed, and end up taking every day for 3 years. 08/01/2012 - Paraxotine 20 mg

12/2024- reinstated 5mg (.0740g)after cold turkey. First tapering 07/01/2025 = 1.2% , 09/01/2025 - another 1.4%. 10/01/2025- 4.79mg (.0716g) holding until further notice........04/17/26 resumed taper 0714g (4.78mg). 05/20/2026- .0712g (4.76mg, .28% cut). 06/09/2026- .0708g (4.73mg .56% cut). 06/30/2026 - .0706g (4.72mg .33%). 07/28/2026 - .0700g (4.68mg, .85%).09/01/26 - .0698g (4.66mg, .29%).

  • Author

Thanks @Raymond

 

Im currently reading through your SA thread as we speak on page 13 😂

I see a lot of similarities in our journeys. 

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

  • Author

Thanks for the support @Chippy

 

❤️👊👌

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

Great, @Richie. Have you done something in particular?

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

  • Author

Hi @skamen

nothing my partner came in and comforted me then brought in my 11 month old little girl and it seemed to just pass. Probably a little window.

 

 

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

3 hours ago, Richie said:

Thanks @Raymond

 

Im currently reading through your SA thread as we speak on page 13 😂

I see a lot of similarities in our journeys. 

😂, wow, do I have that many pages,? 😂.   

 

So far my symptoms usually the same

Anxious, anxiety, fear, but they have been gone for a while now again ...

 

Just the nerve pain but not bad and sometimes left side headache.  

 

Sometimes, the stomach but I'm impress that it's gone again and probably for weeks now...

 

I only mention the symptoms that bothers me.  

08/01/2009- Klonopin 1mg, but took only .25mg when needed, and end up taking every day for 3 years. 08/01/2012 - Paraxotine 20 mg

12/2024- reinstated 5mg (.0740g)after cold turkey. First tapering 07/01/2025 = 1.2% , 09/01/2025 - another 1.4%. 10/01/2025- 4.79mg (.0716g) holding until further notice........04/17/26 resumed taper 0714g (4.78mg). 05/20/2026- .0712g (4.76mg, .28% cut). 06/09/2026- .0708g (4.73mg .56% cut). 06/30/2026 - .0706g (4.72mg .33%). 07/28/2026 - .0700g (4.68mg, .85%).09/01/26 - .0698g (4.66mg, .29%).

  • Author

@Raymond you have 53 pages 😂

 

how is your motivation and pleasure now is it getting better? 

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

  • Author

@Chippy

hi mate just looking for some advice.

will the cortisol spikes stop aslong as I hold? Or will they be in the windows and wave fashion? 
 

hope your good pal 

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

8 hours ago, Richie said:

@Chippy

hi mate just looking for some advice.

will the cortisol spikes stop aslong as I hold? Or will they be in the windows and wave fashion? 
 

hope your good pal 

Hey bud it’s just part of it mate. I think cortisol issues plague a lot of us right through our recovery’s to a greater or lesser extent. And yes it’s all experienced in windows and waves. 

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Woke up with hypersensitivity to sound 😞 

feel like this is getting worse going back on seems like a wrong decision now. Tinnitus is worse getting loads of spots and red marks 

Mirtazapine for 3 weeks august 2025 15mg made me numb didn’t know why took an overdose of 10x 15mg tablets.

 

reinstated at 11 weeks due to symptoms and inpatient stay. 

currently on 3.75mg mirtazapine

 

symptoms/ anhedonia, slightly blurred vision, tinnitus, toxic naps 

depression, anxiety, pins and needles 

Oh, Richie, our ordeal is endless... I have other hellish symptoms: cortisol spikes, sleepiness, zero motivation, fatigue... plus Inhumane anhedonia, but we MUST hold on with hope and believe in the body strength to reach homeostasis.

 

 

2011-2023 Paxil

2023-2024 Effexor

Since February 2024 in anhedonia caused by the long use of AD

February 2024-March 2025 drug after drug after drug... 70 rTMS sessions, 8 ketamin infusions-nothing worked

March 2025 CT upon doctor "advice" from Desipramine, Viibryd, Lithium at high doses all together in 6 days

Since then awful withdrawal: unbearable anxiety, panic attacks, adrenaline rushes, hot flashes, muscle pain over all the body, insomnia, depression, intrusive thoughts, brain fog

Current tapering Mirtazapine : December 29,2025-3 mg, February,15, 2025-2,7 mg, February,28-2,5 mg, March,8-2 mg, March,14-1,5 mg, March,20-0 mg

7 hours ago, Richie said:

getting loads of spots and red marks 

Mirtazapine majorly affects histamine receptors. 

Check out this link....eating high histamine foods and histamine liberators can increase cortisol, anxiety, etc.

https://antidepressantrecovery.org/topic/228-histamine-intolerance-food-lists/?do=getNewComment

 

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for refux/150 mg calcium citrate/algae oil for omega 3/ginger 400 mg as needed for nausea

 

"... your strength will be in keeping calm..."-Isaiah 30:15

18 hours ago, Richie said:

Woke up with hypersensitivity to sound 😞 

feel like this is getting worse going back on seems like a wrong decision now. Tinnitus is worse getting loads of spots and red marks 

So sorry Richie. Don’t forget it all happens in waves and windows. It can feel like worse but it’s just the pattern of stabilisation.  We’re here for you mate. 

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

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