SarahMc: Struggling with a year of multiple drug changes

July 25Jul 25

Author

2 minutes ago, LostinCanada said:
Hey, we are all trying to cope with this Insanity.....this week has been a rollercoaster for me too. Lots of deep breaths. 💯

I saw that! I hope your headache has eased 💜💜💜

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

1

July 25Jul 25

Author

3 minutes ago, mstimc60 said:
That's exactly the time when you should be posting! That's why we're here--to get you through the tough times!

Thanks @mstimc60, you're the best 💜. What a crazy situation we've all found ourselves in.

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

1

July 25Jul 25

Just now, SarahMc said:
Thanks @mstimc60, you're the best 💜. What a crazy situation we've all found ourselves in.

Oh yeah! Sometimes when I think back about my WD and recovery, I can see how easy it was for me to get myself wound up into all sorts of mental knots! Its all part of the journey.

Started Paxil for GAD in 1999

Unsuccessful taper attempt in 2006

Paxilprogress helped with a successful taper completed in 2009

Using therapy and CBT to manage my anxiety

I offer advice based on my experience. Nothing I share is intended to be medical or therapy advice.

2

July 25Jul 25

7 minutes ago, SarahMc said:
I saw that! I hope your headache has eased 💜💜💜

This made me laugh because yes I'm the end it was just a migraine aura. The dr had me terrified it was a TIA especially with how fast he got me in for an MRI, which you know is near to impossible in Canada. Now I just need to convince my CNS I am okay and safe. 💯

I am not a medical professional. My comments are based on my personal experience and information on SA.

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for refux/150 mg calcium citrate/algae oil for omega 3/ginger 400 mg as needed for nausea

"... your strength will be in keeping calm..."-Isaiah 30:15

1

July 25Jul 25

Author

1 hour ago, LostinCanada said:
This made me laugh because yes I'm the end it was just a migraine aura. The dr had me terrified it was a TIA especially with how fast he got me in for an MRI, which you know is near to impossible in Canada. Now I just need to convince my CNS I am okay and safe. 💯

I’m glad all is well and that you can laugh about it now 💜. I’ll be working on convincing my CNS of the same thing tonight 😅.

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

2

July 26Jul 26

7 hours ago, SarahMc said:
Thanks @Fullhealing you're right as always. Apologies for my freak out, I'm just struggling with the neuroemotions today. Whatever it is, I'll figure it out. It's just another hurdle to overcome in this process, and we all have them. 💜💜
Appreciate you as always and hope you're doing a bit better today.

Sarah dear, this whole process is blowing us all out of proportion so please don't be hard on yourself and certainly don't be embarrassed to share.

I'm glad you brought this up so we can try to help you figure this out and make you feel less alone in this.

I hope you're a little calmer now.

please keep us posted 🩷

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

1

July 26Jul 26

@SarahMc its what we're here for x

2016 - Sertraline 50mg

2016 - Sertraline 100mg.

I didnt know better and rarely took it consistently.

June 2024 - went down to 75mg

2025 - Down to 50mg

2026 - down to 25mg

April 2026 - hit by withdrawal and kindling

Reinstated April 2026 - 25mg

May 27th 2026 - Upped to 50mg

1

July 26Jul 26

Hey @SarahMc

Just caught up with your WD/fake Uti. I am sorry to read. Lic is so helpful bless her. We would be lost with out her I think!

You have this. Now you know this is just WD you can be aleast be reassured it will pass given some time. In the words of LIC, 'what a journey'!

Hope today is easier. Thank you for all you do here supporting others whilst having a hard time yourself.

xxxxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

2

July 26Jul 26

10 hours ago, SarahMc said:
Thanks LiC 🙏 💜 I definitely won't start a taper for a while yet, neuroemotions just getting the better of me today 🫣. If this an adverse reaction of some sort I will find ways to cope until I'm much more stable. And I shouldn't have rushed to that conclusion anyways, apologies I'm a bit embarrassed. One day I will learn not to post when I'm in the middle of an intense freak out! Thanks for weighing in, always appreciate your wisdom.

No need, this forum is here for us to support eachother.

These drugs can cause all sorts of confusing symptoms that ramp up and change out of nowhere, it's natural to be concerned.

Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all.

Perhaps you should consider this post an artistic work of fiction written for entertainment purposes.

Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants

15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects)

Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise

1 month taper to 0mg

Last dose April 2023

Severe withdrawal syndrome with many physical symptoms

Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.

1

July 26Jul 26

Author

Thanks all, much appreciated as always. I’m really struggling, I didn’t sleep at all last night because of the discomfort. I’ll hopefully be seeing a doctor tomorrow to confirm for sure whether this is a UTI or something else. Apologies if I’m a bit more absent from here than usual while I get this sorted out.

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

July 26Jul 26

4 minutes ago, SarahMc said:
Thanks all, much appreciated as always. I’m really struggling, I didn’t sleep at all last night because of the discomfort. I’ll hopefully be seeing a doctor tomorrow to confirm for sure whether this is a UTI or something else. Apologies if I’m a bit more absent from here than usual while I get this sorted out.

Hope you feel better soon. Keep us updated if you're feeling up to it. Thinking of you!

2016 - Sertraline 50mg

2016 - Sertraline 100mg.

I didnt know better and rarely took it consistently.

June 2024 - went down to 75mg

2025 - Down to 50mg

2026 - down to 25mg

April 2026 - hit by withdrawal and kindling

Reinstated April 2026 - 25mg

May 27th 2026 - Upped to 50mg

1

July 26Jul 26

12 minutes ago, SarahMc said:
Thanks all, much appreciated as always. I’m really struggling, I didn’t sleep at all last night because of the discomfort. I’ll hopefully be seeing a doctor tomorrow to confirm for sure whether this is a UTI or something else. Apologies if I’m a bit more absent from here than usual while I get this sorted out.

Oh @SarahMc so sorry for the sleepless night, definitely makes everything so much worse.

I'm glad you're going to get checked first to rule out other possibilities and for your peace of mind as well.

Please keep updating if you up for it, I'll be thinking of you ❤️

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

1

July 27Jul 27

21 hours ago, SarahMc said:
Thanks all, much appreciated as always. I’m really struggling, I didn’t sleep at all last night because of the discomfort. I’ll hopefully be seeing a doctor tomorrow to confirm for sure whether this is a UTI or something else. Apologies if I’m a bit more absent from here than usual while I get this sorted out.

No need to appolgise @SarahMc I hope the doctor can shed some light on if this is an UTI or not. Hope today is easier and get some more sleep tonight. xxxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

1

July 27Jul 27

Author

Thanks all 💜💜. Today’s update is that I may have freaked out for nothing. Yesterday afternoon my UTI symptoms started improving quickly and this morning they’re pretty minimal. I’m going to wait it out another couple days and hope they keep improving instead of going to the doctor today. I did get some d-mannose which seems to be helping (thanks @LostinCanada) so I think this is UTI that’s just a bit more stubborn than the ones I’ve had before.

On the downside, it seems like my body fighting the infection and the lack of sleep have amplified my WD symptoms. I woke up last night with a horrific headache, the worst I’ve had in a couple months, and I’ve just generally had a WD setback the past couple days. Hoping a few days of rest will get me back on track.

Appreciate the support everyone, thanks for keeping me out of my crazy WD-brain induced spiral! 😅😂

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

3

July 27Jul 27

You got this and you'll get back on track in no time ❤️

2016 - Sertraline 50mg

2016 - Sertraline 100mg.

I didnt know better and rarely took it consistently.

June 2024 - went down to 75mg

2025 - Down to 50mg

2026 - down to 25mg

April 2026 - hit by withdrawal and kindling

Reinstated April 2026 - 25mg

May 27th 2026 - Upped to 50mg

1

July 27Jul 27

3 hours ago, SarahMc said:
Thanks all 💜💜. Today’s update is that I may have freaked out for nothing. Yesterday afternoon my UTI symptoms started improving quickly and this morning they’re pretty minimal. I’m going to wait it out another couple days and hope they keep improving instead of going to the doctor today. I did get some d-mannose which seems to be helping (thanks @LostinCanada) so I think this is UTI that’s just a bit more stubborn than the ones I’ve had before.
On the downside, it seems like my body fighting the infection and the lack of sleep have amplified my WD symptoms. I woke up last night with a horrific headache, the worst I’ve had in a couple months, and I’ve just generally had a WD setback the past couple days. Hoping a few days of rest will get me back on track.
Appreciate the support everyone, thanks for keeping me out of my crazy WD-brain induced spiral! 😅😂

So great to hear it's getting better and it makes perfect sense that the other symptoms would rear their ugly heads, the system is working extra hard and God forbid they give us a break..

Get some good rest @SarahMc hopefully everything will ease very soon 🩷🩷

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

1

July 27Jul 27

SarahMc, very happy to hear the UTI is setting down, yes our systems sure do give us a run for our money. Definitely don't over think it, our bodies are amazing and have the capably of healing themselves. I definitely agree with you on not letting WD get in our heads, I know I've let that happen more than I would of liked. Sometimes it's easier said than done for sure. Sending special thoughts that things settle and yes definitely get some well needed rest. 🤗

Dec 23 Citalopram 15mg

13 March 24 13.5mg

27 March 24 10mg

12 March 24 7.5mg

20 March 24 6mg

10 Aug 24 5mg

24 Aug 24 4mg

2 Sept 24 3.5mg

11 Sept 24 3mg

19 Sept 24 2.5mg

26 Sept 24 2mg

5 Oct 24 1.5mg

12 Oct 24 1mg

17 Oct 24 Jumped off.

1

July 28Jul 28

You got this @SarahMc x

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

July 28Jul 28

Author

Well I think it’s safe to say this UTI has thrown me into a bad wave. I’m the worst I’ve been in a long while. I know I’ll come back out of it but it’s hard to see the other side right now. Before this I had been making decent progress so I really hope I can get back there soon.

I’d really love to hear from others who got sick or injured, thrown into a wave, and then recovered to their pre-wave baseline.

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

July 28Jul 28

3 minutes ago, SarahMc said:
Well I think it’s safe to say this UTI has thrown me into a bad wave. I’m the worst I’ve been in a long while. I know I’ll come back out of it but it’s hard to see the other side right now. Before this I had been making decent progress so I really hope I can get back there soon.
I’d really love to hear from others who got sick or injured, thrown into a wave, and then recovered to their pre-wave baseline.

Im so sorry to hear this Sarah. As I mentioned to you yesterday I was thrown into a bad one after that really bad sunburn on my back. I was convinced this was it, no way out this time. But i got back to baseline. This is so unpredictable that you could feel better again tomorrow or in 3 days time. Flow with the wave, surrender and distract yourself. You WILL feel better and this WILL pass. ❤️

2016 - Sertraline 50mg

2016 - Sertraline 100mg.

I didnt know better and rarely took it consistently.

June 2024 - went down to 75mg

2025 - Down to 50mg

2026 - down to 25mg

April 2026 - hit by withdrawal and kindling

Reinstated April 2026 - 25mg

May 27th 2026 - Upped to 50mg

1

July 28Jul 28

Author

1 hour ago, cherrysquid said:
Im so sorry to hear this Sarah. As I mentioned to you yesterday I was thrown into a bad one after that really bad sunburn on my back. I was convinced this was it, no way out this time. But i got back to baseline. This is so unpredictable that you could feel better again tomorrow or in 3 days time. Flow with the wave, surrender and distract yourself. You WILL feel better and this WILL pass. ❤️

Thanks as always @cherrysquid 💜

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

July 28Jul 28

2 minutes ago, SarahMc said:
Thanks as always @cherrysquid 💜

Im bad today too, we can float together 😂❤️

2016 - Sertraline 50mg

2016 - Sertraline 100mg.

I didnt know better and rarely took it consistently.

June 2024 - went down to 75mg

2025 - Down to 50mg

2026 - down to 25mg

April 2026 - hit by withdrawal and kindling

Reinstated April 2026 - 25mg

May 27th 2026 - Upped to 50mg

July 28Jul 28

Author

14 minutes ago, cherrysquid said:
Im bad today too, we can float together 😂❤️

💜💜💜

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

July 28Jul 28

2 hours ago, SarahMc said:
Well I think it’s safe to say this UTI has thrown me into a bad wave. I’m the worst I’ve been in a long while. I know I’ll come back out of it but it’s hard to see the other side right now. Before this I had been making decent progress so I really hope I can get back there soon.
I’d really love to hear from others who got sick or injured, thrown into a wave, and then recovered to their pre-wave baseline.

So sorry @SarahMc it must have been a hard blow especially with all the stress involved, it could take some time to get back to baseline but no doubt you will and hopefully soon 🤍

Try to stay calm as possible, pressure is such a fueller!

Hugs!

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

2

July 28Jul 28

Author

4 hours ago, Fullhealing said:
So sorry @SarahMc it must have been a hard blow especially with all the stress involved, it could take some time to get back to baseline but no doubt you will and hopefully soon 🤍
Try to stay calm as possible, pressure is such a fueller!
Hugs!

Thanks @Fullhealing, the anxiety symptoms are high today but I'm doing my best.

Hugs right back, I hope your big wave has started to ease a bit 💜🤗

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys.

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

1

SarahMc: Struggling with a year of multiple drug changes

Featured Replies

Top Posters In This Topic

Most Popular Posts

SarahMc

SarahMc

SarahMc

Create an account or sign in to comment

Top Posters In This Topic

Most Popular Posts

SarahMc

SarahMc

SarahMc

Account

Navigation

Search

Configure browser push notifications

Chrome (Android)

Chrome (Desktop)

Safari (iOS 16.4+)

Safari (macOS)

Edge (Android)

Edge (Desktop)

Firefox (Android)

Firefox (Desktop)