Cheeky: Paxil and Seroquel Long Term Use

April 6Apr 6

Accchh, Cheeky. I was so happy about your window. It's a heartbreak for me to see this wave come on. I know how disappointed you must feel.

Your body knows how to heal as evidenced by the window. Hang tight, girl. The windows will come. ❣️

Sept 1993 Began paroxetine 20 mg for anxiety and depression- worked like a charm.

1st taper - Aug 1995 tapered over 3 weeks before getting pregnant- great at first, crashed at one month. White knuckled it through 2 miscarriages. Spring 1996 (?) Reinstated paroxetine 20 mg.

2nd taper- Spring 2008 tapered off paroxetine over 4 months. Summer 2008 crashed horribly, nearly incapacitated by WD; Summer 2008-Summer 2009 tried 4 different ADs, none as effective as paroxetine. Summer 2009 Reinstated 20 mg paroxetine, not as effective as previously.

3rd taper- Jun 19, 2019 began 10 mg paroxetine, 10 mg fluoxetine for one week. Jun 26 20 mg fluoxetine, 5 mg paroxetine for one week. Jul 3- 20 mg fluoxetine + lorazepam (0.5 mg) as needed up to 2x/day. Aug 12- 30 mg fluox; Sept 3- .5 mg clonazepam daily; end lorazepam; Sept 5- 40 mg fluox;

End of 2019- returned to paroxetine 20 mg/day most of the year, 30mg/day in the winter.

BEGIN 4th TAPER ATTEMPT: Jul 13 2025- 30 -> 25 mg; 10 Sept -> 22.5mg; 3 Oct -> 20 mg; 10 Oct -> hold 2 weeks; 2 Nov -> 19.5 mg; 9 Nov -> 19 mg; 16 Nov -> hold 1 week; 22 Nov -> 18.6 mg; 30 Nov -> 18.2 mg; 7 Dec -> hold 1 week; 14 Dec -> 17.8 mg; 21 Dec -> 17.5 mg; 28 Dec -> 17.1 mg; 4 Jan 2026 -> 16.7 mg -> hold 2 weeks ; 28 Jan -> 16.4 mg; 1 Feb -> 16.0 mg; 8 Feb -> 15.7 mg; 15 Feb -> hold 2 weeks; 1 Mar -> 15.5 mg; 8 Mar -> 15.2 mg; 15 Mar -> hold; 5 Apr -> 14.9.

Supplements: Vit D, Magesium L-threonate, Vit C, Zinc, Melatonin, Multivitamin

April 6Apr 6

2 hours ago, cheeky said:

Okay update,

So I went to Korea for a holiday and I've been feeling really good for the last three weeks. It's been five months since I held my dose since I had the complications with my medications and I have slightly gotten better as my windows have gotten more but I'm back into a wave the last couple of days and I'm feeling really disheartened because I thought I could eventually start my taper again. I don't want to do anything until my nervous system is calm as possible but I also really want to get off these drugs. I feel like I'm just wasting time. I just f Don't understand how you can feel so good and positive one day and then once in a wave you crumble again.

Hey @cheeky

Im loving you had a good time and a window in Korea! Such great news.

I know you want off the drug, that makes sense. You are right though, to not rush and rock the boat. I know the waves and windows can feel endless and brutal, but your hold has been paying off. I’d hold for longer. Get the stable platform and then consider a taper plan from there. Be worth thinking seriously about potentially a more gentle micro taper when you recommence. Chippy

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

April 6Apr 6

Author

1 hour ago, Chippy said:

Hey @cheeky

Im loving you had a good time and a window in Korea! Such great news.

I know you want off the drug, that makes sense. You are right though, to not rush and rock the boat. I know the waves and windows can feel endless and brutal, but your hold has been paying off. I’d hold for longer. Get the stable platform and then consider a taper plan from there. Be worth thinking seriously about potentially a more gentle micro taper when you recommence. Chippy

Thanks @Chippy.,

I have been doing the micro taper previously I think my percentage was too big for my brain to handle . After all my years on this and the challenges trying to come off the wrong way I think my brain in ultra sensitive and will take me much longer then most people . What a trap im

in . The will always be a silver lining to this 😞

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

April 6Apr 6

Author

1 hour ago, gardengirl2 said:

Accchh, Cheeky. I was so happy about your window. It's a heartbreak for me to see this wave come on. I know how disappointed you must feel.

Your body knows how to heal as evidenced by the window. Hang tight, girl. The windows will come. ❣️

Thanks @gardengirl2 your such a sweetheart . I hope your doing well on your taper xx

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

1

April 6Apr 6

32 minutes ago, cheeky said:

Thanks @Chippy.,

I have been doing the micro taper previously I think my percentage was too big for my brain to handle . After all my years on this and the challenges trying to come off the wrong way I think my brain in ultra sensitive and will take me much longer then most people . What a trap im

in . The will always be a silver lining to this 😞

Hey Cheeky

There will be a silver linings I’m sure!

Looking at your signature your holding due to a misdose and formulation change? I’m sure these events have just caused a lot of the destabilisation.

Not sure what your previous taper looked like. Your footer suggests 4% followed by 1% in July? I can see you estimate you did a 4.7% cut as part of the misdose/formulation change in oct.

Did you take tiny daily decreases? Have a read here. Might be useful.

Micro Tapering

You will get there eventually. I know it doesn’t feel like it in the midst of wave. Xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

April 6Apr 6

Author

34 minutes ago, Chippy said:

Hey Cheeky

There will be a silver linings I’m sure!

Looking at your signature your holding due to a misdose and formulation change? I’m sure these events have just caused a lot of the destabilisation.

Not sure what your previous taper looked like. Your footer suggests 4% followed by 1% in July? I can see you estimate you did a 4.7% cut as part of the misdose/formulation change in oct.

Did you take tiny daily decreases? Have a read here. Might be useful.

Micro Tapering

You will get there eventually. I know it doesn’t feel like it in the midst of wave. Xxx

@Chippy

this is the reason I've been holding for 5 months

March 2025

• Restarted tapering:

– Paxil: 3.5% reduction

– Seroquel: 3% reduction both at the same time

June 2025

• Decision made to taper one medication at a time only

• Paxil: 4% reduction

July 2025

• Paxil reduced further to approximately 8.40 mg (total ~5% reduction)

Octobee 2025 – Formulation Change

• Changed Seroquel from liquid to compounded powder

During this period, an accidental dosing error occurred

Approximately 10× i Seroquel dose taken for two weeks then when I changed back to liquid suspension I dropped my Seroquel by 4.7% accidentally

• This occurred while nervous system was already destabilised

• Began full medication hold due to withdrawal symptoms and instability

• Current doses at hold start:

– Paxil: 8.25 mg

– Seroquel: 6.5 mg

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

April 6Apr 6

13 minutes ago, cheeky said:

@Chippy

this is the reason I've been holding for 5 months

March 2025

• Restarted tapering:

– Paxil: 3.5% reduction

– Seroquel: 3% reduction both at the same time

June 2025

• Decision made to taper one medication at a time only

• Paxil: 4% reduction

July 2025

• Paxil reduced further to approximately 8.40 mg (total ~5% reduction)

Octobee 2025 – Formulation Change

• Changed Seroquel from liquid to compounded powder

During this period, an accidental dosing error occurred

Approximately 10× i Seroquel dose taken for two weeks then when I changed back to liquid suspension I dropped my Seroquel by 4.7% accidentally

• This occurred while nervous system was already destabilised

• Began full medication hold due to withdrawal symptoms and instability

• Current doses at hold start:

– Paxil: 8.25 mg

– Seroquel: 6.5 mg

Ouch! Im sorry Cheeky. That must have been rough. Glad you are getting some nice windows. Stablisation is coming!

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

April 6Apr 6

Author

13 minutes ago, Chippy said:

Ouch! Im sorry Cheeky. That must have been rough. Glad you are getting some nice windows. Stablisation is coming!

It sure is very very slowly unfortunatly but I have today I have been getting better . It's just that a wave hits and you feel like your going backwards .

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

April 6Apr 6

Author

2 minutes ago, cheeky said:

sure is very very slowly unfortunatly but I have today I have been getting better . It's just that a wave hits and you feel like your going backwards .

🙃 I will rewrite that. It's just slow unfortunately but I have been progressively getting better. It's just that when a wave hits you feel like you're going backwards it's my fear that's speaking.

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

2

April 6Apr 6

56 minutes ago, cheeky said:

🙃 I will rewrite that. It's just slow unfortunately but I have been progressively getting better. It's just that when a wave hits you feel like you're going backwards it's my fear that's speaking.

I totally get that! Wave brain!

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

April 6Apr 6

1 hour ago, cheeky said:

🙃 I will rewrite that. It's just slow unfortunately but I have been progressively getting better. It's just that when a wave hits you feel like you're going backwards it's my fear that's speaking.

Right with you on that one ,hoping for much better days ahead for you

2016 - 2019 Sertraline 25mg highest dose 100mg

2019 C Ted 25mg Bad withdrawals

01/2020 reinstated 25mg

06/2020 - 12/2021 tapered from 100mg to 6mg jumped off .bad withdrawals like before .

06/2022 reinstated 25mg

10/2023 started taper of 25mg not sure of starting drops

04/2025 5mg

06/2025 4.1mg

08/2025 3.5mg

10/2025 3.1 mg

12/2025 2.5mg

01/2026 to present 2.27mg

April 6Apr 6

8 hours ago, cheeky said:

@Chippy

this is the reason I've been holding for 5 months

March 2025

• Restarted tapering:

– Paxil: 3.5% reduction

– Seroquel: 3% reduction both at the same time

June 2025

• Decision made to taper one medication at a time only

• Paxil: 4% reduction

July 2025

• Paxil reduced further to approximately 8.40 mg (total ~5% reduction)

Octobee 2025 – Formulation Change

• Changed Seroquel from liquid to compounded powder

During this period, an accidental dosing error occurred

Approximately 10× i Seroquel dose taken for two weeks then when I changed back to liquid suspension I dropped my Seroquel by 4.7% accidentally

• This occurred while nervous system was already destabilised

• Began full medication hold due to withdrawal symptoms and instability

• Current doses at hold start:

– Paxil: 8.25 mg

– Seroquel: 6.5 mg

@cheeky hey girl... honestly your body has done amazing considering all the above.

I held 6 months with no dose changes or upsets and was still waving and windowing....lol👋👋👋🪟🪟🪟

You are a pro, you've got this...let it flow over you. 😘🙏❤️

I am not a medical professional. My comments are based on my personal experience and information on SA.

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for refux/150 mg calcium citrate/algae oil for omega 3/ginger 400 mg as needed for nausea

"... your strength will be in keeping calm..."-Isaiah 30:15

1

April 6Apr 6

Author

6 hours ago, LostinCanada said:

@cheeky hey girl... honestly your body has done amazing considering all the above.

I held 6 months with no dose changes or upsets and was still waving and windowing....lol👋👋👋🪟🪟🪟

You are a pro, you've got this...let it flow over you. 😘🙏❤️

Thanks @LostinCanada❤️

Six months might sound long but not long considering how strong these drugs can be and the accumulative effects of past cuts . Sometimes there's really no reason why things happen. It could get easier for you later on nobody knows that's the problem with all of this. I'm just grateful I've had 100% normal days and feeling good but I'm also not on the lower doses yet either.
I just never seen to get used to being in a wave when I've had so many of them before, I know what to expect but it never makes it easier

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

1

April 6Apr 6

Author

12 hours ago, Beehive said:

Right with you on that one ,hoping for much better days ahead for you

Thanks @Beehive well done for getting so low on your dose

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

1

April 9Apr 9

On 4/7/2026 at 7:41 AM, cheeky said:

I just never seen to get used to being in a wave when I've had so many of them before, I know what to expect but it never makes it easier

I get this completely. You have to say over and over again "it's just a wave, it will pass". Try and distract. It's so so hard.

Hope you're doing OK today.

Wombat

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

April 9Apr 9

Author

45 minutes ago, Wombat said:

I get this completely. You have to say over and over again "it's just a wave, it will pass". Try and distract. It's so so hard.

Hope you're doing OK today.

Wombat

Thanks for asking .

had a really bad day yesterday and just stayed in bed and tried to sleep it off . I haven't had a day like that in a long time . I let myself feel sorry for myself .
today I'm at work and I feel off but am coping . I think I'm better at work as I'm distracted . At home I tend to focus on how im Feeling .
I hope your doing well

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

April 9Apr 9

Yes, depending on how bad I am, I also find work a distraction. (If I can get out of bed to get there!! - mostly I can.)

I'm sorry you weren't doing well yesterday and that today you will keep improving and find that window!!

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

April 9Apr 9

Author

6 minutes ago, Wombat said:

I'm sorry you weren't doing well yesterday and that today you will keep improving and find that window!!

Thanks it really helps getting that support . I too dread the mornings , it's such an effort getting up and facing the world .

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

April 12Apr 12

Hi Cheeky, Hoping today is a good day for you. Sending love and encouragement 💕

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

April 13Apr 13

Author

On 4/12/2026 at 10:44 AM, Wombat said:

Hi Cheeky, Hoping today is a good day for you. Sending love and encouragement 💕

Your so lovely thank you .

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

April 13Apr 13

Author

Update:

On 26 March, I changed to a new syringe for my liquid Paxil dosing. After checking measurements, I realised that the new syringe delivers slightly less than my previous one, which has resulted in an unintentional reduction of approximately 4%.

Based on this, my dose has effectively gone from 8 mg to around 7.7 mg.

I’ve now been on this adjusted dose for about 2 weeks. I initially had a really good week, followed by a wave over the past several days, which I now understand could be my system responding to this reduction.

My plan is to hold at this dose and allow my system to stabilise before making any further changes. I seem to be the Queen 👸 of making mistake's , so let's see how this pans out .

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

1

April 13Apr 13

Dear Cheeky, what a frustrating inconvenience.

However, the positive is that you are on less med - Yay!!! And you picked up on the error. That was very clever of you. I am not sure I would have noticed.

How are you going? Are you able to function during the wave?

I did receive a syringe tip just recently to buy a box of the same brand syringe. (I think they come in boxes of 100). Maybe something you could consider?

Hoping for a quick recovery from this drop and back into a window.

Wombat

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

1

April 13Apr 13

46 minutes ago, cheeky said:

Update:

On 26 March, I changed to a new syringe for my liquid Paxil dosing. After checking measurements, I realised that the new syringe delivers slightly less than my previous one, which has resulted in an unintentional reduction of approximately 4%.

Based on this, my dose has effectively gone from 8 mg to around 7.7 mg.

I’ve now been on this adjusted dose for about 2 weeks. I initially had a really good week, followed by a wave over the past several days, which I now understand could be my system responding to this reduction.

My plan is to hold at this dose and allow my system to stabilise before making any further changes. I seem to be the Queen 👸 of making mistake's , so let's see how this pans out .

Sorry about the mismatch in syringes @cheeky, so many variables, can be hard to keep track! Your doing great. Youll settle down, plus a few more drops less, win!

Chippy

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys.

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

1

April 13Apr 13

Author

9 minutes ago, Chippy said:

plus a few more drops less, win!

Yeah any less is a bonus

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

1

April 13Apr 13

Author

19 minutes ago, Wombat said:

And you picked up on the error

I knew there as something wrong as I couldn't work out why I was feeling like this after having great windows

On Paxil since 1995. Seroquel added 2014 after withdrawal crash. History of too-fast tapers/reinstatements.

21 April 2025 taper two drugs at once

Paxil 4% Seroquel 3.5% per month

that ended up being too much and changed to one drug at a time

13 Jul 2025: 4% Paxil cut

29 Jul 2025: 5% Paxil cut

6 Aug 2025: began hold

Oct 2025: changed from liquid to powder and accidentally took 10x Seroquel dose for 2 weeks by mistake

23 Oct 2025: returned to liquid with accidental 4.7% Seroquel cut

Holding both drugs to stablize

Holding at Paxil 8.25 mg / Seroquel 6.5

Paxil taper

22/4 8.23 29/4 8.20 5/5 8.15 13/5 8.05 3/6 8 11/6 7.95

Cheeky: Paxil and Seroquel Long Term Use

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