Yes ❤️

I’ll add 2 cents here then shut up. You can compound your own. I tapered off mirtazapine once before. I made my own liquid form of it. Im a ex lab tech & determined the concentration/ml that I needed. Ground the tablets with mortar & pestle. Then added the ground power to the correct amount suspension agent (Ora-Plus) to get the mg/ml that you need. . But you’re uncomfortable with doing it yourself a compounding pharmacy can make a liquid for you as well. I think a liquid form is much more manageable for making small dose adjustments.

@Pokey449

Thank you for your two cents! I appreciate it. Did you make a suspension so that you had 15 mg/mL? Or what were your ratios?

4/29/26

Very activated day yesterday. All day long. Deep Electricity and agitation and aka that lasted well into the evening. Hard to stay quiet. Great distress.

Took dose as usual, as too distressed to think clearly.

9:15 pm 14.79 mg mirt (.1026 g)

Got sleepy

10:00 pm pounding, sweating, nauseated, bouncy sensations

Restless, activated night

Woke at 3:30 am electric twisting sensations in gut and pelvis

Now 4:37 am Feeling inner aka starting

Panic rising , feels like whole body is bouncing and pulsating in bed

Nauseated and deep electric stomach

21 minutes ago, Finni said:

4/29/26

Very activated day yesterday. All day long. Deep Electricity and agitation and aka that lasted well into the evening. Hard to stay quiet. Great distress.

Took dose as usual, as too distressed to think clearly.

9:15 pm 14.79 mg mirt (.1026 g)

Got sleepy

10:00 pm pounding, sweating, nauseated, bouncy sensations

Restless, activated night

Woke at 3:30 am electric twisting sensations in gut and pelvis

Now 4:37 am Feeling inner aka starting

Panic rising , feels like whole body is bouncing and pulsating in bed

Nauseated and deep electric stomach

Aka is brutal, Finny so sorry you have to go through this, you are really coping so bravely!

I just wonder what are you planning? holding, continuing to reduce?

Just now, Fullhealing said:

Aka is brutal, Finny so sorry you have to go through this, you are really coping so bravely!

I just wonder what are you planning? holding, continuing to reduce?

Dr. Horowitz gave me two options and I’m trying to decide which one to go with.

I can either start going down .1 mg per every week or a couple of weeks or I can gradually move 3 mg of my current dose earlier in the day.

Something’s Gotta give though! I can’t keep doing this at this intensity day after day. Mirt really seems to be too much for my nervous system now for sure.

7 minutes ago, Finni said:

Dr. Horowitz gave me two options and I’m trying to decide which one to go with.

I can either start going down .1 mg per every week or a couple of weeks or I can gradually move 3 mg of my current dose earlier in the day.

Something’s Gotta give though! I can’t keep doing this at this intensity day after day. Mirt really seems to be too much for my nervous system now for sure.

It definitely seems like your system is strongly resisting the drug, awful like this all day so sorry!! I personally think the first option might be easier although who knows, it's just a matter of trying and seeing, what do you think?

5 minutes ago, Fullhealing said:

It definitely seems like your system is strongly resisting the drug, awful like this all day so sorry!! I personally think the first option might be easier although who knows, it's just a matter of trying and seeing, what do you think?

If this drug has turned on me like it feels like it has, it seems like I need to start tapering instead of continuing to try to make it work for me by splitting.

Dr. Horowitz mentioned reducing before he mentioned splitting the dose

2 minutes ago, Finni said:

If this drug has turned on me like it feels like it has, it seems like I need to start tapering instead of continuing to try to make it work for me by splitting.

Dr. Horowitz mentioned reducing before he mentioned splitting the dose

Sure do sound like it! just my opinion of course but maybe start already on option from tomorrow, the other is always there if it doesn't work out, why did he suggest splitting, short half life?

Edited April 29Apr 29 by Fullhealing

6 minutes ago, Fullhealing said:

Sure do sound like it! just my opinion of course but maybe start already on option from tomorrow, the other is always there if it doesn't work out, why did he suggest splitting, short half life?

It does not have a short half-life, but it does peak very quickly, and then start dropping in the bloodstream. The medication peaks within two hours, even though the half-life is 20 to 40 hours so in a sensitive system, it can come on really strong and then wear off in a way.

He said it can be a way of reducing the toxic effects and reducing the feeling of withdrawal at the same time

14 minutes ago, Finni said:

It does not have a short half-life, but it does peak very quickly, and then start dropping in the bloodstream. The medication peaks within two hours, even though the half-life is 20 to 40 hours so in a sensitive system, it can come on really strong and then wear off in a way.

He said it can be a way of reducing the toxic effects and reducing the feeling of withdrawal at the same time

I see, so maybe it's worth splitting it first and seeing how you react and then continuing to reduce from there, this in itself may reduce the intensity and hopefully get you out of akathisia, just throwing out ideas, hope it's ok and I'm not confusing you even more 🙏

Edited April 29Apr 29 by Fullhealing

15 minutes ago, Fullhealing said:

I see, so maybe it's worth splitting it first and seeing how you react and then continuing to reduce from there, this in itself may reduce the intensity and hopefully get you out of akathisia, just throwing out ideas, hope it's ok and I'm not confusing you even more 🙏

Right now, my intuition is telling me to go down from .1026 g to .1020 g and not even mess with splitting (reducing from 14.79 mg to 14.7 mg

I can’t imagine trying to get my body used to another “input” at a different time of day, especially since that time would be changing for who knows how long as I tried to work the dose earlier and earlier in the day. If it were as easy as just adding in 3 mg in the morning, I would be more inclined to try. But having to change the time over the course of weeks just seems very disrupting.

Edited April 29Apr 29 by Finni

2 hours ago, Finni said:

@Pokey449

Thank you for your two cents! I appreciate it. Did you make a suspension so that you had 15 mg/mL? Or what were your ratios?

it’s common to double the dose. So 1:2 ratio. 15mg drug 30ml water.

I’d stick to powder for the minute till you get lower. Swapping to liquid can be destabilising and a journey of its own.

7 minutes ago, Finni said:

Right now, my intuition is telling me to go down from .1026 g to .1020 g and not even mess with splitting (reducing from 14.79 mg to 14.7 mg

I can’t imagine trying to get my body used to another “input” at a different time of day

Can try it and see how you go. Sorry how much you have to deal with atm. One day Finni this will be a distant memory.

@f

2 hours ago, Finni said:

Thank you for your two cents! I appreciate it. Did you make a suspension so that you had 15 mg/mL? Or what were your ratios?

@Finni to answer your question yes you can make any concentration you want/need. 15,7.5,3.75mg/ml for example. Then draw doses with a 3ml or 1ml syringe. But what you want to do is totally your choice. I just wanted to share that the liquid form of mirtazapine was easy for me to manage as compared to shaving tablets or dealing with varied strengths of capsules.

11 minutes ago, Chippy said:

Can try it and see how you go. Sorry how much you have to deal with atm. One day Finni this will be a distant memory.

Thank you for that encouragement, dear Chippy ❤️

23 minutes ago, Finni said:

Right now, my intuition is telling me to go down from .1026 g to .1020 g and not even mess with splitting (reducing from 14.79 mg to 14.7 mg

I can’t imagine trying to get my body used to another “input” at a different time of day, especially since that time would be changing for who knows how long as I tried to work the dose earlier and earlier in the day. If it were as easy as just adding in 3 mg in the morning, I would be more inclined to try. But having to change the time over the course of weeks just seems very disrupting.

I know it could be scary without knowing the reaction but obviously we always know in retrospect, if you have strong intuition I would think it's enough to try, can always change course later.

Edited April 29Apr 29 by Fullhealing

@Finni I just caught up on your thread. A few things I feel I need to mention.

When grinding your pills and putting them in capsules, you do not add filler.

Also each capsule weighs differently so they need to individually be weighed.

I use a mix of shaved tablets and with the leftover bits, I put them in capsules and take those. I have not noticed any difference between the two.

I would not make liquid at this point or a compounded capsule...it adds a variable and I think stability is more important first. I personally had a horrible experience with compounding.

Trust your gut, if it is saying reduce, there is only one way to know.

You are doing amazing....❤️🙏

14 minutes ago, LostinCanada said:

Also each capsule weighs differently so they need to individually be weighed.

Yes. I would, if it were me, each time you make up a dose, tare/zero the scale with the capsule empty on it, then add the powder. You don’t need to take the weight into your number then and it deals with the capsule weight inconsistencies.

57 minutes ago, LostinCanada said:

@Finni I just caught up on your thread. A few things I feel I need to mention.

When grinding your pills and putting them in capsules, you do not add filler.

Also each capsule weighs differently so they need to individually be weighed.

I use a mix of shaved tablets and with the leftover bits, I put them in capsules and take those. I have not noticed any difference between the two.

I would not make liquid at this point or a compounded capsule...it adds a variable and I think stability is more important first. I personally had a horrible experience with compounding.

Trust your gut, if it is saying reduce, there is only one way to know.

You are doing amazing....❤️🙏

Thank you so much for taking the time to see how I’m doing. I didn’t think it was possible to get worse after holding for 5 weeks since the full pill dose disruption. And it’s been over two months of being at 14.7 mg.

I hope I have held long enough

@LostinCanada

@Chippy

5 minutes ago, Finni said:

I hope I have held long enough

@LostinCanada

@Chippy

Honestly @Finni I think you have...your experience still seems like you are sensitive to this drug. We know more drug isn't the answer. ❤️🙏

7 minutes ago, Finni said:

I hope I have held long enough

@LostinCanada

@Chippy

You do seem to be reacting to the drug so hopefully you will get a sign when you drop slightly that the body is happy with that decision. Listening to what it says is the only way.

@LostinCanada

If I have not taken mirtazapine in a powdered form or small pieces, crushed in a capsule yet, do I need to take it that way at my normal dose before I start to taper?

20 minutes ago, Finni said:

@LostinCanada

If I have not taken mirtazapine in a powdered form or small pieces, crushed in a capsule yet, do I need to take it that way at my normal dose before I start to taper?

It shouldn't make any difference. I figure the capsule probably gives similar protection as the coating and a solid piece, therefore absorption rate should be similar.