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Finni: Sensitized by Many Med changes and Mirtazapine

Featured Replies

  • Author

4/30/26

I had a very activated day yesterday. Big vestibular symptoms, too. Inner vibrations and some shaking hands morning…pacing morning and midday. Some terror and twisting sensations in stomach that would surge at times.

Attended taper support circle evening.

Good appetite afternoon and evening.

Big pounding sensations and vibrations increased in the evening as well.

Watched some deleted scenes from love on the spectrum and an Appletv series.

Played NYT games.

9:15 pm took 14 mg mirt (reduced from .1026 g to .1020 g)

10:00 pm heat, rumbling, and pounding came back

Then I slept until around 4:30 AM

Deep headache, and a lot of deep electricity, rotary motor feelings and terror going on now at 6:30 am.

Regret reduction

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

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  • NBJ71
    NBJ71

    And please don’t beat yourself up about going to the hospital, you were looking for a solution to help yourself. I did exactly the same thing Finni and so have many others. The hospital made me so muc

  • Fullhealing
    Fullhealing

    I know it feels endless @Finni I'm so sorry, but let me assure you are not permanently damaged, it always amazes me anew what the body can overcome and you are no exception. You've been through a

  • Finni
    Finni

    My affirmation:    “I am healing, and my body is strong enough to get through this. Healing is happening even when I can’t feel it.”

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  • Author

I totally expected to feel relief. I really really did like almost immediately when I reduced in February -and now I just feel worse. I’m very scared at how intense this is.

Something deep within me last night said wait a minute you haven’t gone six weeks before making a change….. and is your head hurt hurting? No you haven’t been having headaches at all. Maybe I should’ve counted that as a win.

It’s the it’s the te*ro* that is affecting me the most right now and the head pressure. And just that feeling like something is not at all safe.

Edited by Finni

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

Just now, Finni said:

I totally expected to feel relief. I really really did like almost immediately and now I just feel worse and I’m very very scared at how intense this is.

Something deep within me last night said wait a minute you haven’t gone six weeks before making a change….. and is your head hurt hurting? No you haven’t been having headaches at all. Maybe I should’ve counted that as a win.

It’s the it’s the horrible terror that is affecting me the most right now and the head horrible head pressure.

just surrender to it, it's just highs and lows that play with you, you just stop believing them and deal logically with the symptoms, you know it's another wave that will pass and then come back and pass.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.

Current Medications: Mirtazapine, Lasea (lavender oil) before bed.

------------------------------------------

Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mg

Note: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.

4 hours ago, Finni said:

I totally expected to feel relief. I really really did like almost immediately when I reduced in February -and now I just feel worse. I’m very scared at how intense this is.

Something deep within me last night said wait a minute you haven’t gone six weeks before making a change….. and is your head hurt hurting? No you haven’t been having headaches at all. Maybe I should’ve counted that as a win.

It’s the it’s the te*ro* that is affecting me the most right now and the head pressure. And just that feeling like something is not at all safe.

Hey @Finni it is quite expected to not feel positive change immediately, this of course does not indicate anything.

You know the complexity of the process, so waves of varying intensity will hit.

Just remember how grateful your system will be by cleaning this poison out as well as you are very strong to deal with the temporary consequences that most likely will come.

Keep up the bravery! xxxx

Edited by Fullhealing

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 20% 0.0358g (2mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of anxiety and sleep that seems to continue to improve.

Thinking of you @Finni I know today has been rough and your reduction didn’t go as you planned. I hope you feel better as the day goes on and get out on the golf cart. Xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author
49 minutes ago, Chippy said:

Thinking of you @Finni I know today has been rough and your reduction didn’t go as you planned. I hope you feel better as the day goes on and get out on the golf cart. Xxx

It’s this is really over the top

My body wasn’t ready for another reduction apparently

I think I need to just go back to .1026 g

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

1 minute ago, Finni said:

It’s this is really over the top

My body wasn’t ready for another reduction apparently

I think I need to just go back to .1026 g

Only you know if that’s the right move @Finni wish there were certainties in all this. Xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

26 minutes ago, Finni said:

It’s this is really over the top

My body wasn’t ready for another reduction apparently

I think I need to just go back to .1026 g

@Finni I don't see any change from the latest updates and the chance of a worsening in such a short time is slim so most likely this is anxiety talking, but you're feeling it yourself, if you think it's right to go back up again, then go for it, just try to keep your expectations realistic, it won't be symptom-free in any case unfortunately..

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 20% 0.0358g (2mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of anxiety and sleep that seems to continue to improve.

Sending you healing, strength, and a big hug. xxxx

You can get through any stage, no matter how difficult it is!

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 20% 0.0358g (2mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of anxiety and sleep that seems to continue to improve.

1 minute ago, Fullhealing said:

Sending you healing, strength, and a big hug. xxxx

You can get through any stage, no matter how difficult it is!

💯 xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Hello -

I’m just popping in to say please don’t worry about me if I’m not on the forum for a while.

Just need to step away and get direction from just a couple of people for now.

Gotta hunker down and hold at my usual .1026 g for awhile longer until my cns can handle a change.

Love to all 💕💕

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

@Finni You need to do what feels right for you ,so I'm sure everyone will understand. This whole process is so unpredictable hope and pray you find stability and peace soon 🙏

2016 - 2019 Sertraline 25mg highest dose 100mg 

2019 C Ted 25mg Bad withdrawals 

01/2020 reinstated 25mg 

06/2020 - 12/2021 tapered from 100mg to 6mg jumped off .bad withdrawals like before .

06/2022 reinstated 25mg 

10/2023 started taper of 25mg not sure of starting drops 

04/2025 5mg

06/2025 4.1mg

08/2025 3.5mg 

10/2025 3.1 mg

12/2025 2.5mg

01/2026 to present 2.27mg 

 

 

11 hours ago, Finni said:

Hello -

I’m just popping in to say please don’t worry about me if I’m not on the forum for a while.

Just need to step away and get direction from just a couple of people for now.

Gotta hunker down and hold at my usual .1026 g for awhile longer until my cns can handle a change.

Love to all 💕💕

Hey @Finni You must do what you need to do. We are here for you when you need. I hope things stablise for your soon. xxxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

I’m in a scary situation. I tried to reduce to .1020 g and then went right back to .1026 g after being shocked by severity of withdrawal.

Now I’m even more reactive to mirtazapine and more reactive to what I’m assuming is cortisol and also as the mirtazapine levels drop in afternoon and evening.

I really wish I had never reduced.

Akasthisia is violent now.

I didn’t realize I was stable compared to this.

Not sure what to do.

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

1 minute ago, Finni said:

I’m in a scary situation. I tried to reduce to .1020 g and then went right back to .1026 g after being shocked by severity of withdrawal.

Now I’m even more reactive to mirtazapine and more reactive to what I’m assuming is cortisol and also as the mirtazapine levels drop in afternoon and evening.

I really wish I had never reduced.

Akasthisia is violent now.

I didn’t realize I was stable compared to this.

Not sure what to do.

Hey Finni,

This is awful. I can see a pattern though. Each time you think you are at your worse, you eventually decide to reduce your dose, only to discover there is a worse state underneath it. This is a cruel place to find yourself.

I can only say, based on this pattern, that a very long hold without chasing relief with changes in doses is the right course.

Your only other option is to keep tapering, but that doesn't seem to be possible for you right now, and jumping doses around is never good.

I wish there was more that could be done. But we know that sometimes, very long holds are required to allow the body to work all this complexity out for us.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author
24 minutes ago, Chippy said:

Hey Finni,

This is awful. I can see a pattern though. Each time you think you are at your worse you eventually decide to reduce your dose, only to discover there is a worse state underneath it. This is a cruel place to find yourself.

I can only say, based on this pattern, that a very long hold without chasing relief with changes in doses is the right course.

Your only other option is to keep tapering, but that doesn't seem to be possible for you right now, and jumping doses around is never good.

I wish there was more that could be done. But we know that sometimes, very long holds are required to allow the body to work all this complexity out for us.

Reductions have brought almost immediate relief in the past, so I was blindsided.

I wish like everything I could have known what was coming. It’s beyond anything I could’ve imagined, and it’s do hard to believe I’ll get back to where I was.

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

1 minute ago, Finni said:

Reductions have brought almost immediate relief in the past, so I was blindsided.

I wish like everything I could have known what was coming. It’s beyond anything I could’ve imagined, and it’s do hard to believe I’ll get back to where I was.

So maybe this is the sign, that a hold is the right path. It is awful that we have to trial and error our way out of all of this. I hate this for you Finni. Trust your body to level out.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

@Finni I’m at a similar dose to you but a different drug. I feel completely stuck at the moment and a lot of things are getting worse. New and intense symptoms. I knew it would get more difficult though not how intense things would be. I haven’t had severe akathisia like you describe and I feel for you. 😢

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg.  2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day) 

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014;

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

  • Author
16 minutes ago, Catbird said:

@Finni I’m at a similar dose to you but a different drug. I feel completely stuck at the moment and a lot of things are getting worse. New and intense symptoms. I knew it would get more difficult though not how intense things would be. I haven’t had severe akathisia like you describe and I feel for you. 😢

Thank you 🩷

I’m so sorry you’re suffering.

The a.k.a. doesn’t last all day, thankfully- just very intense when it hits

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

  • Author
54 minutes ago, Catbird said:

I’m at a similar dose to you but

I’m still at a pretty high dose milligram wise

I was stating the pill weight

It looks like you’re getting close to zero 👏

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

Hi, I’m sorry for what you’re going through. How do you know how much you’re reducing? How are you able to be so precise? Do you use the liquid form?

Medication History

  • January – March 2025: Use of Xanax (Alprazolam).

  • Late March 2025: Mirtazapine 15 mg for only two weeks.

  • May 2025 – December 2025: Use of Rivotril (Clonazepam) (8 drops in the evening, 5 drops in the morning).

  • December 1, 2025: Discontinuation of Rivotril (Clonazepam) after a 4-month taper. Experienced various physical pains but no depression or agitation. Developed tinnitus. Since then: chronic agitation, vertigo, diagnosed by psychiatrists as "automated anxiety," and persistent tinnitus.

The Final Breakdown (February 2026)

After discontinuing Rivotril (Clonazepam), I suffered trauma from "polypharmacy," triggering a violent reaction:

  • February 6–16: Rapid rotation between medications (Mirtazapine, Olanzapine, Zoloft, Cipralex).

  • February 17: I decided NOT to take the dose because the tinnitus had become unbearable.

  • February 17 – March 22: Total discontinuation. The abyss: subjective akathisia, debilitating panic attacks, constant chest tightness.

Chaos and harm caused by dosage variations in March:

  • March 22–23: Reintroduction of Mirtazapine 7.5 mg. Subjective akathisia improved, but severe chest pain appeared.

  • March 24–27: Dosage reduced to 3.5 mg. Reintroduction of Rivotril (Clonazepam) (1 drop on March 26 and 27). It was after this reduction that physical pain, immediate and violent, exploded.

  • March 28: I discontinued Rivotril (Clonazepam) and returned to Mirtazapine 7.5 mg. I felt extremely ill for a week with a "strange head" and pain. Then, slowly, I stabilized slightly. Tinnitus decreased. I have good days, but I still have a lot of agitation.

Recent events:

  • April 18: Reduced Mirtazapine to 5 mg, but was forced to return to 7.5 mg the following day. Since then: strange sensation in the head, back pain, violent tinnitus.

  • April 25: Reduced to 6.8 mg of Mirtazapine. Worse than before: severe back pain, depression, insomnia, stomach pain, muffled ears, tinnitus in the head. Increased agitation, visceral akathisia appearing throughout the day, headache.

  • Currently, April 29: Reduced Mirtazapine dosage to 6.8 mg

  • Author

@Gilda

I bought scales that measure .0000 g

AND (A&D) model EJ-54D2

Edited by Finni

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

5 hours ago, Gilda said:

Hi, I’m sorry for what you’re going through. How do you know how much you’re reducing? How are you able to be so precise? Do you use the liquid form?

Same @Finni xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Big reaction to mirt after 9:15 dose

Almost immediate agitation and restlessnes, nausea

4:30 am Still going- deep buzzing, ter*o*, agitation rising and twisting in gut

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late

 

 

1 hour ago, Finni said:

Big reaction to mirt after 9:15 dose

Almost immediate agitation and restlessnes, nausea

4:30 am Still going- deep buzzing, ter*o*, agitation rising and twisting in gut

So sorry this is present for you @Finni . I had a terrible time trying to reduce Mirtazapine. I did a 6 month taper (same story as others - way too fast) as my doctor said it would be fine. I ended in a heap with severe agitation and distress. I was put back on my SSRI which I'm currently tapering now. However it looks like you've been on the same dose for at least 2 months and having severe WD symptoms. I feel for you. I've had a wrenching gut for 8 days now so I empathise. 🤗

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg.  2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day) 

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014;

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

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