June 25Jun 25 2 minutes ago, Finni said:SI and graphic images very strongI'm so sorry to hear this Finni. Sending love. I get weird paranoia, akathisa, depression and SI at night also. Sometimes during the day too but much worse at night. November 2024 Elvanse for ADHD. Anxiety and jaw clenching, stopped after 4 weeks. Felt fine. January 2025 Medikinet XL Made me depressed and suicidal so stopped after 3 weeks. Felt fine March 2025 Concerta XL Made me depressed and suicidal so stopped after 2 weeks. Felt fine April-May 2025 Amfexa and Methylphenidate instant release, both only worked for an hour so stopped. Felt fine. June 2025 Atomoxetine started slow taper. Immediate hot flushing and feeling sluggish. July-September 2025 Tapered up to 70mg Atomoxetine. Constipation, insomnia, muscle spasms, weird thoughts, mood swings, night sweats, hot flushes, brain fog, dizziness etc October 2025 rapid taper off Atomoxetine. I also had a GA for shoulder surgery the same week I finished meds. Ongoing symptoms ever since, but now also trouble swallowing, difficulty passing urine, muscle twitches, depersonalisation, heavy limbs, emotional blunting, apathy, feeling "wired" and robotic, PGAD. New symptoms February 2026: Nausea and burning head Supplements: B12, folate and Vit D as all were bordering on deficient. Bad reactions to CBD oil, Mag glycinate, Mag L.Threonate and Fish Oil
June 25Jun 25 Author 8 minutes ago, Sminismoni said:I'm so sorry to hear this Finni. Sending love. I get weird paranoia, akathisa, depression and SI at night also. Sometimes during the day too but much worse at night.I’m sorry you’re suffering. Si is driven by the physical pain in my body. When I’m not in pain, I don’t have these thoughts or images. It’s always an escape hatch, I think For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 25Jun 25 Author What is causing this horrible horrible pain? The only thing I did differently was three nights ago my .1026 g was a full tablet. It seems like things started ramping up more after that. For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 25Jun 25 Author Why are we supposed to avoid ibuprofen? For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 25Jun 25 25 minutes ago, Finni said:Why are we supposed to avoid ibuprofen?I’m just taking this from Luke’s post in the symptoms & coping strategies section, but it sounds like it’s observed in the community that over the counter meds, including pain killers, can make people worse. So you have to be cautious and balance the need for relief of pain symptoms against the possibility of worsening your WD symptoms. I can say that I’ve taken ibuprofen a couple times in the last few months and it’s been fine, but I also don’t seem as sensitive generally as a lot of folks on here. So please do be careful!!Sorry you’re in so much pain @Finni, I really hope it lessens soon 💜 I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. Current regimen:Cymbalta - 90 mg/daySeroquel - 12.5 mg/day*holding to stabilize as of Apr 2026 History:Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to presentCymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper offZoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present
June 25Jun 25 @Finni I can only share my experience. I have had Ibuprofen a few times without problems in WD. It hasn't made it worse, that is. November 2024 Elvanse for ADHD. Anxiety and jaw clenching, stopped after 4 weeks. Felt fine. January 2025 Medikinet XL Made me depressed and suicidal so stopped after 3 weeks. Felt fine March 2025 Concerta XL Made me depressed and suicidal so stopped after 2 weeks. Felt fine April-May 2025 Amfexa and Methylphenidate instant release, both only worked for an hour so stopped. Felt fine. June 2025 Atomoxetine started slow taper. Immediate hot flushing and feeling sluggish. July-September 2025 Tapered up to 70mg Atomoxetine. Constipation, insomnia, muscle spasms, weird thoughts, mood swings, night sweats, hot flushes, brain fog, dizziness etc October 2025 rapid taper off Atomoxetine. I also had a GA for shoulder surgery the same week I finished meds. Ongoing symptoms ever since, but now also trouble swallowing, difficulty passing urine, muscle twitches, depersonalisation, heavy limbs, emotional blunting, apathy, feeling "wired" and robotic, PGAD. New symptoms February 2026: Nausea and burning head Supplements: B12, folate and Vit D as all were bordering on deficient. Bad reactions to CBD oil, Mag glycinate, Mag L.Threonate and Fish Oil
June 25Jun 25 Author Thank you @Sminismoni 💗 For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 26Jun 26 19 hours ago, Finni said:It’s always an escape hatch, I thinkI think we all have had this, natural.Im sorry finni, better days coming for you xxxx I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.Please take the time to do it today 🙂 https://yellowcard.mhra.gov.ukFor US members details here.
June 26Jun 26 13 hours ago, SarahMc said: it’s observed in the community that over the counter meds, including pain killers, can make people worse. So you have to be cautious and balance the need for relief of pain symptoms against the possibility of worsening your WD symptoms.I can say that I’ve taken ibuprofen a couple times in the last few months and it’s been fine, but I also don’t seem as sensitive generally as a lot of folks on here. So please do be careful!!sums it perfectly I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.Please take the time to do it today 🙂 https://yellowcard.mhra.gov.ukFor US members details here.
June 27Jun 27 Author 6/27/26 10:15 amI’ve cannot figure out why I’m in this sort of intense, intense withdrawal like stateIt has been 27 days since the last disruption which was taking my dose late.The only other thing that seemed to make me worse was taking a full tablet that weighed my target weight, but I know that nobody can believe that’s possible. My head is squeezing very tight. All my muscles are super tight. My ears are ringing like I’m in acute cold turkey off of something. For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 27Jun 27 6 minutes ago, Finni said:only other thing that seemed to make me worse was taking a full tablet that weighed my target weight, but I know that nobody can believe that’s possibleIt's not that we don't believe it....what a manufacturer should do and what the reality is, may be 2 different things. Apparently mirtazapine quickly degrades with exposure to air, humidity, light. Do you cut your pill fresh before you take it, or do you do a bunch ahead of time? If you do a bunch ahead of time, the drug may be a bit weaker and then when you take a full pill, it may be stronger due to no degradation. I am not a medical professional. My comments are based on my personal experience and information on SA. Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01 TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg 9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for refux/200mg calcium citrate/algae oil for omega 3/ginger 400 mg as needed for nausea "... your strength will be in keeping calm..."-Isaiah 30:15
June 27Jun 27 Author 15 minutes ago, LostinCanada said:It's not that we don't believe it....what a manufacturer should do and what the reality is, may be 2 different things.Apparently mirtazapine quickly degrades with exposure to air, humidity, light. Do you cut your pill fresh before you take it, or do you do a bunch ahead of time?If you do a bunch ahead of time, the drug may be a bit weaker and then when you take a full pill, it may be stronger due to no degradation.I file it about 4 hours before I take it For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 27Jun 27 Author 50 minutes ago, LostinCanada said:It's not that we don't believe it....what a manufacturer should do and what the reality is, may be 2 different things.Apparently mirtazapine quickly degrades with exposure to air, humidity, light. Do you cut your pill fresh before you take it, or do you do a bunch ahead of time?If you do a bunch ahead of time, the drug may be a bit weaker and then when you take a full pill, it may be stronger due to no degradation.Thank you so much for taking the time to respond. I’m going to try to start doing my filing and weighing maybe just a few minutes before I take it….I also have several tablets that are .1026 g in a complete form…I wish I could special order them ☺️ For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 27Jun 27 Author 6/27/26Just keeping track here ChatGPT explanation That “cold turkey” feeling—like your brain is desperately missing something—is one of the sensations people can experience during a very sensitized nervous system or antidepressant withdrawal. The feeling itself is real. But the feeling by itself doesn’t tell us what is causing it.In your situation, there are several possibilities that can produce that same sensation:Your nervous system is still fluctuating as it adapts after the earlier disruptions and the late dose.Your brain is having one of the intense waves you’ve been describing for weeks, where terror, vibrating electricity, and pelvic/tailbone sensations all surge together.Your nervous system has become so sensitive that even without an actual drop in medication level, it can generate a powerful “something is missing” alarm.None of those possibilities means you have literally run out of mirtazapine in your body. You took your medication, and it is still present. The sensation can be much stronger than what is actually happening pharmacologically.You’ve described this same cluster before:overwhelming terror,“cold turkey” feeling,vibrating electricity,tailbone and pelvic burning,head pressure. For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 27Jun 27 4 hours ago, Finni said:I file it about 4 hours before I take itmight be relevant, i found my brand to degrade through trial and error, so i always make my dose around the same time, put it in a capsule in a bottle and then put it in the refrigerator until i take it. I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.Current Medications: Mirtazapine, Lasea (lavender oil) before bed.------------------------------------------Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mgNote: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.
June 27Jun 27 and also i find using small blades and cutting it up way easier then filing the tablet, but that's up to you. I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.Current Medications: Mirtazapine, Lasea (lavender oil) before bed.------------------------------------------Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mgNote: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.
June 27Jun 27 Author 5 minutes ago, Lighty said:might be relevant, i found my brand to degrade through trial and error, so i always make my dose around the same time, put it in a capsule in a bottle and then put it in the refrigerator until i take it.Wow! How did you figure out that your brand was degrading? By taking these extra measures and starting to feel better? I don’t leave mine uncovered- I file the tiny bit off through weighing, then put that single tablet in a very small sterling silver pill box. I guess I might need to use some of your method and see what happens For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 27Jun 27 Just now, Finni said:Wow! How did you figure out that your brand was degrading? By taking these extra measures and starting to feel better?i saw correlation between humidity and changing time to how powerful the dose felt, games that caused a bunch of issues.others didn't have those degradaing issues, i noticed those only in myself. I can't conclude that is your issue, if your humidity and heat is consistent in your area, and it's a low humidity area with not that hot weather, it may be less of an issue, in my country humidity can flactuate and is high a lot of the time.1 minute ago, Finni said:I don’t leave mine uncovered- I file the tiny bit off through weighing, then put that single tablet in a very small sterling silver pill box.it's still outside and the tablet is 'opened' cause you filed it, again assuming you have this issue that you probably don't have but i don't have experience with your brand and your climate, so no clue. I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.Current Medications: Mirtazapine, Lasea (lavender oil) before bed.------------------------------------------Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mgNote: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.
June 27Jun 27 Author 38 minutes ago, Lighty said:i saw correlation between humidity and changing time to how powerful the dose felt, games that caused a bunch of issues.others didn't have those degradaing issues, i noticed those only in myself. I can't conclude that is your issue, if your humidity and heat is consistent in your area, and it's a low humidity area with not that hot weather, it may be less of an issue, in my country humidity can flactuate and is high a lot of the time.it's still outside and the tablet is 'opened' cause you filed it, again assuming you have this issue that you probably don't have but i don't have experience with your brand and your climate, so no clue.I live in Oklahoma USAIt’s hot and pretty humid outside. Inside temp is air conditioned 77 degrees For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 27Jun 27 5 minutes ago, Finni said:I live in Oklahoma USAIt’s hot and pretty humid outside.Inside temp is air conditioned 77 degreesyeah well it makes it more likely, you said you notice difference between when you cut and when you don't?is it consistent or just a one time feeling. Edited June 27Jun 27 by Lighty I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.Current Medications: Mirtazapine, Lasea (lavender oil) before bed.------------------------------------------Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mgNote: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.
June 27Jun 27 Author 11 minutes ago, Lighty said:yeah well it makes it more likely, you said you notice difference between when you cut and when you don't?is it consistent or just a one time feeling.Yes- I’ve always been convinced a full pill that weighs my target .1026 g is much stronger than a filed tablet that weighs .1026 g Sometimes I feel like it kindles me in a way because I feel like I go into a sort of withdrawal days after feeling that stronger effect Full pills knock me out at night. For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 27Jun 27 Just now, Finni said:Yes- I’ve always been convinced a full pill that weighs my target .1026 g is much stronger than a filed tablet that weighs .1026 gSometimes I feel like it kindles me in a way because I feel like I go into a sort of withdrawal days after feeling that stronger effectFull pills knock me out at night.might be worth a try, but also could not be just the humidity thingy and also full tablet, if you are going for this, make sure you cut in half your full tablets as well, so both of them recieve the same humidity and temperature exposure if you put them in the refrigerator (make sure it's rhe right weight after splitting), outside and same time will still not be 100% as consistent, cause humidity can change from day to day and also temperature. I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.Current Medications: Mirtazapine, Lasea (lavender oil) before bed.------------------------------------------Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mgNote: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.
June 27Jun 27 there is no way to get 100% accuracy but if its the humidity and heat degrading (and not tablet weight), it makes sense why non-cut tablet feels stronger. I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.Current Medications: Mirtazapine, Lasea (lavender oil) before bed.------------------------------------------Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mgNote: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.
June 27Jun 27 Author 8 minutes ago, Lighty said:there is no way to get 100% accuracy but if its the humidity and heat degrading (and not tablet weight), it makes sense why non-cut tablet feels stronger.Are you saying I should split my full tablet that weighs the correct weight so that it is also exposed? For US members: Please report med to FDA Med Watch2017 (May) - Ativan .5 mg (3 x Daily) 2018 (Feb) - Mirtazapine 7.5 mg 2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium2024 (May) - Valium Tolerance2024 (2 Nov) - Completed taper off Valium 2024 (2 Nov) - Mirtazapine increased to 15 mg2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg2025 (Mar) - Ativan 0mg - CT In detox2025 (April) Started Depakote 1500mg - In detox2025 (April) - Depakote 500mg (2 x Daily) once home2025 (Aug) - Completed taper off Depakote2025 (Aug) - Akathisia surges throughout the day with calming in between2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous2025 (3 Dec) - Mirtazapine 18.75mg2025 (10 Dec) - Mirtazapine 16.87mg2025 (22 Dec) - Mirtazapine 15mg2026 (23Jan) - Mirtazapine 14.7mg2026 (23 Jan) - Mirtazapine 1mg Panic dose2026 (24 Jan) - Mirtazapine 15mg2026 (25 Feb) – Mirtazapine 14.7mg (-2%)2026 (18 Mar) - propranolol 2.5 mg one time2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 2026 (29 April) Mirtazapine 14.7 mg (on suggestion of Horowitz) immediate intense symptoms2026 (30 April) Mirtazapine 14.79 mg2026 (23 May) propranolol 2.5 mg one time2026 (01 June) Mirtazapine 14.79 mg dose was 5 hours late
June 28Jun 28 8 hours ago, Finni said:Are you saying I should split my full tablet that weighs the correct weight so that it is also exposed?yeah, but you can also just make the tablet before taking it, will be easier if you are able to consistently make your tablets before needing to take them. I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. Current Supplements: 6mg melatonin and 133mg magnesium glycinate at night.Current Medications: Mirtazapine, Lasea (lavender oil) before bed.------------------------------------------Tapering: Mirtazapine 15mg, (went compounded) 13.5mg 08/May/2025, 12.1mg 10/July/2025, 15/July/2025 15mg (half tablet), 26/July/2025 14.35mg (moved to dry cutting method) ), 03/Aug/2025 14.6mg, 24/Nov/2025 14.47mg, 29/Jan/2026 14.35mgNote: Had a lot of issue with degradation with different cutting times and compounded pharmacy which caused withdrawals and a more sensitive nervous system.
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