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Saar8srl: Stopped Zoloft

Featured Replies

2 hours ago, Saar8srl said:

Tomorrow it will be day 10 of my 1 mg Ri. Do I go higher and could this help me to get more stabilize ? I still have the windows and waves and I don’t know if I have to wait 4 more days or not . Does 1 mg ex actually do something ?

Hi @Saar8srl, the next steps are up to you. You can choose to wait another four days before you make up your mind, you can choose to stick at 1 mg and wait to stabilize here, or you can go a bit higher now ( @Chippy suggested 2 mg).

2 mg might help a bit more, and it might not. RI does not help everyone, unfortunately, and even when it does it most often does not get rid of all of your symptoms. I would not expect to get to a dose where your waves and windows stop altogether. Eventually you will have to decide to stick at a particular dose and ride out the waves and windows until you stabilize. I'm sorry, I know it's really hard.

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. 

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

 

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

 

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  • Chippy
    Chippy

    For the record here we have decided to leave this thread of posts in place rather than remove as the community has done a great job of confirming the forums position on this. We don't tolerate members

  • Sminismoni
    Sminismoni

    Psychiatrist here. Sorry to say but this is simply not true and you are spreading misinformation. It is the same misinformation that drug companies use to market Bupropion - that it has "no withdrawal

  • SarahMc
    SarahMc

    I'm sorry @Saar8srl, I think we all have days where we feel hopeless and lost. I have not had a truly good day in about 10 months, and many days are still brutal. But we know that so many of those who

  • Author

Thank you @SarahMc I think I will like to go and stick to a dose that I van Handel. Let me just wait 4 more days and see if I can go to 2 mg . @Chippy did you suggest this? Thank you all beautiful friends

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

12 hours ago, Saar8srl said:

Thank you @SarahMc I think I will like to go and stick to a dose that I van Handel. Let me just wait 4 more days and see if I can go to 2 mg . @Chippy did you suggest this? Thank you all beautiful friends

Hey, I think waiting a few more days is perfectly sensible.

It is completely up to you, I would not be too worried about 2mg personally, we can't know how you will react to increasing the dose, however you have not seen a worsening or any improvement from what you have said so getting the receptor occupancy up might help.

Just to note you are seeing some waves and windows and this is a good sign and may be evidence of the RI helping.

We are here for you what ever you choose to do. xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

17 hours ago, Saar8srl said:

Does 1 mg ex actually do something ?

Yes. Receptor occupancy can still be very high at low doses for various psychiatric drugs.

We don't have much more than that to go on scientifically but the experiences of others here are that it does as well.

Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all.

 

Perhaps you should consider this post an artistic work of fiction written for entertainment purposes.


Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants

 

15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects)

Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise

1 month taper  to 0mg

Last dose April 2023

Severe withdrawal syndrome with many physical symptoms

Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.

  • Author

Thank you @Chippy and @Luke . Let’s hope I can be a little functional. My only problem is the depression and the fact that I am not able to feel any kind of joy. Question, is there a difference between a classic depression and a chemical one? Can I heal from this and how should I start with setting the first steps to recover. I just want to have hope but it’s so hard to accept that this is the new me.

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

3 hours ago, Saar8srl said:

Thank you @Chippy and @Luke . Let’s hope I can be a little functional. My only problem is the depression and the fact that I am not able to feel any kind of joy. Question, is there a difference between a classic depression and a chemical one? Can I heal from this and how should I start with setting the first steps to recover. I just want to have hope but it’s so hard to accept that this is the new me.

Pleasure. Time is your friend. This isn’t you. This is drug injury. You can recover for sure. Main thing is to not think you can fix this. Patience and acceptance is key. Xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Just curious about my wd. Are there people here who had physical symptoms after 3 months stopping the meds? Could it just happen that something like insomnia and akathisia hits you after 3 4 months?

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

Yes, my symthoms (some of them), not just physical, manifested a few months after my very quick tapering. The same moment when I became "clear" i felt something, but it was almost nothing comped to everything happened later. Horowitz also mentioned that WD symthoms can starts about 7 months after quitting. It is quite consisted with my experience. However I experienced real akathisia (pacing) 6 years after quitting.

But on the other hand, first time in my life when I CT SSRI, it was almost nothing. Some brain fog, cognitive decline and lack of energy, which was present even before, when I was on drug.

Edited by The Dust

2009-2010: Sertraline (50 mg)

2011: Escitalopram (10 mg)

2009-2011: tried Olanzapine (5/2.5mg), Quetiapine  (50/25mg) and Aripriprazole (low dosage)

CT Escitalopram, being free for several moths

2012-2016: Fluoxetine (60 mg)

2016-2017: Venlafaxine (75 mg)

2016: just tried Duloxetine and Maprotiline

2017-2018: Mirtazapine (30/45mg)

2012-2018: Bupropion (300 mg)

2014-2018: Lamotrigine (50/100/150 mg) CT Bupropion, tapering Lamitrogine and Mirtazapine (practically CT, fast tapering)

 

5 hours ago, Chippy said:

Pleasure. Time is your friend. This isn’t you. This is drug injury. You can recover for sure. Main thing is to not think you can fix this. Patience and acceptance is key. Xxx

Saying so much with so few words.

2011-2015 - tapered off 300mg of Venlafaxine after 6 years of use

2005-2021 - 450 mg Bupropion daily

2021-2023 - tapered Bupropion to zero 

 

Hi @Saar8srl I will answer your questions here so it is on your thread. Feel free to just tag me if you have any other questions. 😊

Your message:

I’m new in this wd and still try to understand what is happening to me. Can I ask you some questions?

are you fully healed ?

No I am not. I am still tapering after my reinstatement 3.5 years ago. My CNS is extremely sensitive

How did you experience your wd?

Dp/dr, SI, anxiety, nausea, insomnia, tremors, akathasia, histamine intolerance, bloating, terror, dizziness, neuropathy, crying, monophobia, irritability, sweats, heart palpitations, vision issues, sound sensitivity, aphasia, reflux, phantom smells, body aches

Did you experience depression?

No, though I will get a low mood once in awhile

How long did it last for you ?

Never long

And after 3 months did you still have new symptoms popping up?

Yes

thank you so much if you will be able to take the time to answer my questions. ❤️

I am not a medical professional. My comments are based on my personal experience and information on SA.

 

Paroxetine-2002 onward-20mg/ Citalopram-2007-20 mg-straight switch from paroxetine-back to paroxetine after a month/ Sertraline -25 mg-Dec 2016- given for a month instead of paroxetine (doctor mistake) Oxazepam -10 mg-2016-twice weekly for a couple months for sleep/ Zopiclone -3.75-7.5mg-2020-2022-once a week for sleep/Paroxetine -20 yr+/ Dec2018-May 2022 20 mg/ May 2022 30mg/2022.07.28-2022.08.24 30mg to 0mg/ Prozac-10mg August 24-29 2022/Paroxetine -5mg-2022.11.28-2022.12.04/10mg-Dec 5&6/22/ Prozac-10mg-Dec 8&9/22/Paroxetine -5mg-2022.12.07 to 2023.07.01

 

TAPER-Paroxetine-2023-Jul 2-4.9mg/ Jul 21-4.8mg/Jul 28-4.73mg/Aug 4-4.65mg /Sep 21-4.58 mg/Oct 27-4.56 mg/Dec 5-4.54 mg/2024-Jan 2-4.52 mg/Jan 9-4.51 mg/Jan 17-4.49 mg/Jan 26-4.47mg/Feb 6-4.46mg/Feb 19-4.44mg /Apr 4-4.43mg/Apr 28-4.4 mg/May 5-4.39 mg/May 19-4.36 mg/Jul 2-4.34 mg/Jul 9-4.32mg/Jul 31-4.3 mg/Oct 1-4.29mg/Nov 27-4.25 mg/Dec 5-4.22mg/2025-Jan 5-4.17mg/Feb 2-4.1mg/Mar 7-4.07mg/Apr 23-4.04mg/May 23-4mg/Jun 22-3.99mg/Jun 30-3.95mg/Jul 18-3.92mg/Sep 25-3.9mg/2026-Mar 25-3.85mg

 

9am-paroxetine, 200mg mag bisglycinate/75 mg DGL if needed for refux/150 mg calcium citrate/algae oil for omega 3/ginger 400 mg as needed for nausea

 

"... your strength will be in keeping calm..."-Isaiah 30:15

12 hours ago, Saar8srl said:

Just curious about my wd. Are there people here who had physical symptoms after 3 months stopping the meds? Could it just happen that something like insomnia and akathisia hits you after 3 4 months?

I had physical symptoms from the beginning, but also continued to develop new ones at years off.

Nothing I say is medical advice, it is simply my opinion. I am an anonymous person on an internet forum with no relevant qualifications other than being badly harmed by a drug. For all you know, I could be an idiot. You are making your own decisions and part of that is deciding how much to listen to my opinion, if at all.

 

Perhaps you should consider this post an artistic work of fiction written for entertainment purposes.


Story from SA: LukeUK: Remeron/Mirtazapine Severe Withdrawal - Introductions and updates - Surviving Antidepressants

 

15mg Remeron/Mirtazapine November starting 2022 (severe physical side effects)

Attempted to taper off January 2023, ended up having a major breakdown and going up to 30mg, took weeks to stabilise

1 month taper  to 0mg

Last dose April 2023

Severe withdrawal syndrome with many physical symptoms

Summary: 5 months using Mirtazapine, including 1 month taper ending late April 2023.

  • Author

Please anyone .. my depression is getting worse… I can’t do anything.. it this because the Ri? I can’t believe my life is becoming this way. Never had this before . I can’t do the normal things I used to do. Is heartbreaking. I’m sorry for my negativity but I just feel like this and I don’t know what to do

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

Hey @Saar8srl don't be sorry. I am sad to see things are a little worse for you.

I suspect this is not the RI personally and is just windows and waves.

-You could increase the dose perhaps to 2mg

-Hold and wait for the wave to pass

-Perhaps consider an appointment with Dr Horowitz and get his thoughts. PM me and I can give you more details.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

I live in the Netherlands and don’t have access to that unfortunately . Do you think going to 2 mg would help with the deep depression? I start to think maybe this is just me without the meds because I don’t have anything else instead of anhedonia and some hart rates in the morning ..

Edited by Saar8srl

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

2 minutes ago, Saar8srl said:

I live in the Netherlands and don’t have access to that unfortunately.

Dr H will talk to anyone from all over the world just have to pay and book in for one of his sessions.

3 minutes ago, Saar8srl said:

Do you think going to 2 mg would help with the deep depression?

I could ease things, I don't know this of course. All we can do is carefully increase the dose and watch and observe how you react.

4 minutes ago, Saar8srl said:

I start to think maybe this is just me without the meds because I don’t have anything else instead of anhedonia and some hart rates in the morning ..

This is WD brain lying to you. This is not natural, this is the opposite to that, I think you know this.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

How can you be so sure I have been using Zoloft for 6 years so I could have been depressed without knowing that .

I would like to have an appointment with him If you can give me the information. I looked it up before but I have heard that he doesn’t help people out of the uk.

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

13 minutes ago, Saar8srl said:

How can you be so sure I have been using Zoloft for 6 years so I could have been depressed without knowing that .

Because these drugs, take people with normal issues and emotions and troubles and make them so much worse. Depression is not a disease that you catch. These drug cause some very strong unworldly symptoms, sometimes whilst taking them, and all too often when stopping them.

14 minutes ago, Saar8srl said:

I would like to have an appointment with him If you can give me the information. I looked it up before but I have heard that he doesn’t help people out of the uk.

I will send you the link now in a PM x

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Thank you but I also had a lot to deal with in my childhood and my psychiatrist didn’t work on that instead he give me the pills and I didn’t know back then. The therapie wasn’t really deep that is what I know now and after that my life was very unpleasant and I always had to do everything alone with a little child who is know a teenager. So I think I also had a depression but never like this I guess . I can’t be for sure because I was using Zoloft al this time. The consult is very expensive so you think he will be able to give me more advise than I have already received from you guys ?

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

4 minutes ago, Saar8srl said:

So I think I also had a depression but never like this I guess .

This is the key, not like this...

4 minutes ago, Saar8srl said:

The consult is very expensive so you think he will be able to give me more advise than I have already received from you guys ?

Well he isn't cheap for sure, his thoughts are always welcome though and useful. It is your call. If you can afford it I can't see it would be a bad idea, you may find it reassuring to have his perspective on all this as well as ours, even if it confirms what we are saying. He is very kind and knowledgeable.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Thank you so much @Chippy . did he help you too?

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

3 minutes ago, Saar8srl said:

Thank you so much @Chippy . did he help you too?

Pleasure, No he didn't but we have had many members go to him for reassurance and advice. Another pair of eyes never hurts.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Alright I will see what to do. I am just so sick of feeling like this and thinking this is my life now. Sometimes I think I better have other symptoms which I can deal with . Low mood and depression make life miserable and you just don’t want to be part of life anymore. When you cannot enjoy your life your child and normal thing. What is the use ?

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

  • Author

I just hope I didn’t make my depression worse by Ri. It sure feels like this

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

1 hour ago, Saar8srl said:

I just hope I didn’t make my depression worse by Ri. It sure feels like this

@Saar8srl I think Chippy is right and this is just normal waves and windows. In a wave, when things are really bad, it can feel like there is no hope and often people try to figure out what they think triggered the wave. But in reality most times it's just our nervous system trying to find that stability.

I know you are worried because you don't have a whole bunch of physical symptoms like others on here. I was like that too at the beginning of my withdrawal experience -- really my only symptom was bad anxiety, but it was different than my normal anxiety because it would come and go at random. I would have really good days with basically no anxiety, then terrible days where I was anxious constantly and couldn't sleep at night. I made the mistake of believing that it was my "underlying condition" getting worse and cycled through meds trying to find the "right" one while only making myself worse. Believe me when I say that was a huge mistake and I wish I could go back to last year and do things much differently.

This is not you. This is withdrawal. You have never experienced depression like this, and to make things more obvious you have clear waves and windows. Your nervous system is injured right now, but it is trying hard to recover and it will get better with time and patience.

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. 

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

 

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

 

  • Author

Thank you so much @SarahMc . I am in such a bad place right now. You have no idea. I stayed at home al day can’t do anything exact laying in the bed . I don’t even have feelings only feelings of doom . Did you had other symptoms after that ? I hope for a better day tomorrow…

01-2018 fluoxetine 10 mg two weeks

02-2019 started Sertraline 150 mg with 10 sometimes 5 mg oxazepam for sleep- my sleep was not ok after 150 mg but I felt good

01-August 2025 in one moth quit Sertraline because of the symptoms (getting fat, tired and starting to feel some sadness)

12-2025 quit oxazepam

04-2026 because of major brain zap middle of the night started 25mg one week, up to 50mg next week and get depressed and quit. This was way too soon and a high dose.

I also started oxazepam again

17-Mei 2026 started 10 mg 3 days and 5 mg 2 days in the hospital.

21-5 quit Sertraline

I felt better after 5 days and then crashed again

27-6 quit oxazepam

9-8 RI Zoloft 1mg

31-8 RI Zoloft 2mg

I always take magnesium and fish oil

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