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Fullhealing: Paxil withdrawal

Featured Replies

3 hours ago, Fullhealing said:

Update 24.98.26 11:40am

It only took two days for the system to flare up even more from the kid's multivitamin at almost zero dosage.. no clue how I will fill the deficiency effectively as it is simply impossible only through nutrition, big problem.

My sleep in the last two days has become horrific again with very vivid nightmares that leave a terrible taste throughout the day, yesterday and after a few good days of relief, again a sleep hallucination when trying to rest, seems that the system can't shake the extreme fight or flight mode, I stopped taking short evening walks since it is impossible to escape people on the way which irritates, everything in general turns me on, I can't stand even weak noises, the tinnitus is very loud including eye tics, crazy digestion and the racing thoughts, oh my, catastrophe BUT I have to remind myself that it all makes sense in light of the recent dramatic changes, I just need to wait, wait, and more wait and muster a ton of patience which is not really going well so far so good luck with that.

@Fullhealing . Keep reminding yourself that the body is healing. I'm here to support you.

Hanging in there!

08/01/2009- Klonopin 1mg, but took only .25mg when needed, and end up taking every day for 3 years. 08/01/2012 - Paraxotine 20 mg

12/2024- reinstated 5mg (.0740g)after cold turkey. First tapering 07/01/2025 = 1.2% , 09/01/2025 - another 1.4%. 10/01/2025- 4.79mg (.0716g) holding until further notice........04/17/26 resumed taper 0714g (4.78mg). 05/20/2026- .0712g (4.76mg, .28% cut). 06/09/2026- .0708g (4.73mg .56% cut). 06/30/2026 - .0706g (4.72mg .33%). 07/28/2026 - .0700g (4.68mg, .85%).09/01/26 - .0698g (4.66mg, .29%).

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4 hours ago, Fullhealing said:

It only took two days for the system to flare up even more from the kid's multivitamin at almost zero dosage.. no clue how I will fill the deficiency effectively as it is simply impossible only through nutrition, big problem.

My sleep in the last two days has become horrific again with very vivid nightmares that leave a terrible taste throughout the day, yesterday and after a few good days of relief, again a sleep hallucination when trying to rest, seems that the system can't shake the extreme fight or flight mode, I stopped taking short evening walks since it is impossible to escape people on the way which irritates, everything in general turns me on, I can't stand even weak noises, the tinnitus is very loud including eye tics, crazy digestion and the racing thoughts, oh my, catastrophe BUT I have to remind myself that it all makes sense in light of the recent dramatic changes, I just need to wait, wait, and more wait and muster a ton of patience which is not really going well so far so good luck with that.

I'm so sorry @Fullhealing, a really hope you get some lasting relief soon. I'm with you on the irritability, I still have to walk our dogs every day but sometimes I get so annoyed that I'll even just see someone in the distance walking towards us and I'll get a surge of anger 😅. It's still unbelievable to me the way these drugs mess with us.

I'm with you on this long, long, long hold.

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. 

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

 

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

 

Sending you a blessing, my dear. ❤️‍🩹

SA Thread: https://www.survivingantidepressants.org/forums/topic/33406-nemina-tapering-escitalopram/


AR Thread: https://antidepressantrecovery.org/topic/14-nemina-tapering-escilatopram-and-zolpidem/

 

Drug History

2013 - 2025:  Zolpidem 5 mg

2015 - Oct 2024: Venlafaxine, Sertralin (Zoloft), Paroxetin (Paxil),duloxtin (cymbalta), Citalopram (Celexa), Escitalopram (Lexapro) and more 

 

Current Drugs

L-Thyroxin 75, Estrogen, Progesteron 200

 

Tapering Escitalopram

Until Sept 2024: Setralin/zoloft 75 mg

Oct 2024: Switch to Escitalopram / Lexapro 2mg

Then I tapered over a year from 2mg to 0,32 mg (October 2025).  108 days hold without stabilizing. Resumed taper February 2026:

11 Feb 2026 0.314mg 

18 Feb 2026 0.307mg 

21 Feb 2026 0.302mg

09 Mar 2026 0.297mg

18 April 2026 0,293 mg

18 May 2026 0,285 mg

18 June 2026 0,265 mg

18 July 2026 0,250 mg

18 Aug 2026 0,232 mg

 

Tapering Zolpidem: From 5 mg to 0,7 mg in 12 months,  then just crumbs for several weeks, now 0! (Jan 2025)

 

Other Supplements 

Omega 3, Magnesium Glycinate, Vit D, Calcium, L-theanin.

  • Author

If I catch myself with any symptoms doubt..

SEROTONIN RECEPTORS ARE NOT JUST IN THE BRAIN.

Serotonin (5-HT) receptors are distributed throughout the body and are found on a huge variety of cells, tissues and organs.

Nervous system

• Neurons

• Glial cells

• Astrocytes

• Microglia

• Sensory neurons

• Motor neurons

• Enteric neurons

💪 Muscle cells

• Skeletal muscle-related cells

• Smooth muscle cells — including blood vessels, gut, airways, bladder and reproductive organs

• Cardiac muscle cells

🩸 Blood & cardiovascular system

• Platelets

• Endothelial cells

• Vascular smooth muscle cells

• Cardiac cells

🦠 Digestive system

• Enterochromaffin cells

• Enterocytes

• Enteric neurons

• Smooth muscle cells

• Other epithelial cells

🫁 Lungs

• Airway smooth muscle cells

• Pulmonary vascular cells

• Endothelial cells

• Nerve cells

🧫 Liver

• Hepatocytes

• Hepatic stellate cells

• Cholangiocytes

• Kupffer cells / macrophages

• Vascular cells

🩸 Pancreas

• β-cells

• α-cells

• Other pancreatic cells

• Nerve and vascular cells

🫘 Kidneys

• Renal epithelial cells

• Vascular cells

• Other renal cell populations

🦴 Bone

• Osteoblasts

• Osteoclasts

• Bone-marrow cells

🔥 Adipose tissue

• Adipocytes

• Immune cells

• Stromal/vascular cells

🛡️ Immune system

• T cells

• B cells

• Monocytes/macrophages

• Dendritic cells

• Neutrophils

• Eosinophils

• Mast cells

• Microglia

🩸 Spleen

• Macrophages

• T cells

• B cells

• Dendritic cells

• Monocytes & other immune cells

• Platelets

• Endothelial cells

• Vascular smooth muscle cells

🧬 Lymphatic & immune organs

• Lymph nodes

• Bone marrow

• Thymus

• Immune and stromal cells

🧴 Skin

• Keratinocytes

• Fibroblasts

• Immune cells

• Sensory nerve cells

• Vascular cells

🧬 Reproductive system

• Ovarian cells

• Uterine cells

• Placental cells

• Testicular cells

• Prostate cells

• Smooth muscle and vascular cells

🦋 Endocrine &

other tissues

• Thyroid cells

• Adrenal cells

• Salivary gland cells

• Bladder cells

• Gallbladder cells

• Various epithelial, vascular, immune and connective-tissue cells

…and many other tissues.

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

Pretty much our entire body 😢

Aug 2006 - Sertraline 25/50/75/100mg TO June 2019 - Reduced from 100mg to 50mg over a few months

Sept  2019 - Reduced from 50mg to 25mg lasted a week,  then went back up to 50mg, after a few weeks back up to 100mg.

Oct 2021 - Reduced to 75mg, Dec 2021 (mid) reduced to 50mg , March 2022 - Reduced to 25mg

Oct 2022 - Reduce to 0mg (Immediate withdrawal crying, mood unstable, impending doom, digestive probs, tingling,numbness,burning, brain zaps,  insomnia)

Feb 2023 -  "Panic attack" lasting 14 hours, 2 weeks later start back on 25mg sertraline, 12 hours later severe 'panic attack' with chest pain, tachycardia, restlessness, hyponatraemia, impending doom, racing thoughts, akathisia mild.  Taken to emergency. 

March 2023 back up to 50mg (on medical advice), April 75mg, May 100mg. Back to 75mg within a few weeks due to feeling too stimulated and anxious. 

Nov 2023 resume taper. 70, 65, 60, 55, 50 (March 2024)

April 45mg, May 41mg, June 37mg, July 34mg Aug 31mg, Sept 28mg, Oct 26mg, Nov 25mg, HOLD 

Jan 1st 2025 24mg, Jan 12th 23.5mg, Jan 20th 23mg, Feb 20th 22mg, March 20th 21mg, April 14th 18.9mg, May 5th 17mg, May 28th 15.3mg, July 16th 13.7mg, Aug 26th 12.3mg, Sept 16th 10.5 mg, Sept 22, 10mg, Oct 7th 8.3mg, Nov 4th 8mg, Dec 1st 7.7mg, Dec 26th 7mg 2026 Updose to 7.2mg Mar 20th, Back to 7mg Mar 21. Currently holding

 

Other supplements: Fish oil, Mg citrate/glycinate 150-300mg per day, Ginkgo biloba daily, womens multi vit/min 3 times week, Vitamin C 1000mg night, valerian/passiflora as needed. B12 as needed. Bone support for osteopaenia (Ca/Mg, K, D)

And they thought it was a good idea to create a medication that can mess with just about every cell in your body.

🙄😕

1998 Paroxetine 20mg, getting to 60mg and staying there for many years.

Started reducing by 10mg at a time, December 2018 to June 2019. At 30mg held for 2 and a half years.

Beginning 2023, start micro tapering from 30mg

End 2023 - 18.76. End 2024 - 13.37. End 2025 - 8.58 

2026 - 31 Jan - 8.38, 15 Feb - 8.19, 07 March - 8.06, 14 March - 8.00, 08 April - holding and start liquid transition, 22 May completed liquid transition 8mg (16ml) held for 1 month

27 June - 7.9, 12 July - 7.75, 18 July - 7.6, 25 July - 7.45, 22 August - 7.30,

 

Deuteronomy 31.8 "The Lord Himself goes before you and will be with you; He will never leave you nor forsake you. Do not be afraid; do not be discouraged."

 

  • Author
8 minutes ago, Wombat said:

And they thought it was a good idea to create a medication that can mess with just about every cell in your body.

🙄😕

Lovely isn't it.. more issues more 💰 for the big pocket.. great idea, not for us.

Edited by Fullhealing

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

3 hours ago, Tracey said:

Pretty much our entire body 😢

Yup! Evil what they do to us. I am still shocked how much my body is effected by all this in so many ways.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

How are You doing today, my dear? I hope things are settling a bit.

SA Thread: https://www.survivingantidepressants.org/forums/topic/33406-nemina-tapering-escitalopram/


AR Thread: https://antidepressantrecovery.org/topic/14-nemina-tapering-escilatopram-and-zolpidem/

 

Drug History

2013 - 2025:  Zolpidem 5 mg

2015 - Oct 2024: Venlafaxine, Sertralin (Zoloft), Paroxetin (Paxil),duloxtin (cymbalta), Citalopram (Celexa), Escitalopram (Lexapro) and more 

 

Current Drugs

L-Thyroxin 75, Estrogen, Progesteron 200

 

Tapering Escitalopram

Until Sept 2024: Setralin/zoloft 75 mg

Oct 2024: Switch to Escitalopram / Lexapro 2mg

Then I tapered over a year from 2mg to 0,32 mg (October 2025).  108 days hold without stabilizing. Resumed taper February 2026:

11 Feb 2026 0.314mg 

18 Feb 2026 0.307mg 

21 Feb 2026 0.302mg

09 Mar 2026 0.297mg

18 April 2026 0,293 mg

18 May 2026 0,285 mg

18 June 2026 0,265 mg

18 July 2026 0,250 mg

18 Aug 2026 0,232 mg

 

Tapering Zolpidem: From 5 mg to 0,7 mg in 12 months,  then just crumbs for several weeks, now 0! (Jan 2025)

 

Other Supplements 

Omega 3, Magnesium Glycinate, Vit D, Calcium, L-theanin.

  • Author
5 hours ago, Nemina said:

How are You doing today, my dear? I hope things are settling a bit.

Sweet of you to check in dear @Nemina thank you, I'm flaring up in the last two days but this too shall pass, we know.

How things are going for you? you are struggling as well lately, so sorry, hope today is a bit better?

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

Morning @Fullhealing sorry things are amping a bit for you, I have the same atm, hope today is easier for you today my friend. xxxxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author
18 minutes ago, Chippy said:

Morning @Fullhealing sorry things are amping a bit for you, I have the same atm, hope today is easier for you today my friend. xxxxx

Thank you @Chippy so sorry it's tough for you too, the flare is still in full swing.. I'm exhausted to the max but we know it will go as it comes, we just have to keep crawling..

Hope your day brightens up my friend xxxxx

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

30 minutes ago, Fullhealing said:

we know it will go as it comes, we just have to keep crawling..

Thats the one my friend, glad Im crawling next to you xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

Update 28.08.26 1am

So today, while I'm in a flare-up with extreme restlessness I find myself humming with pleasure, bursting out laughing to some funny shorts only to cry my heart out and fall into atomic depression, irrational fears and unexplained rage a second later.. full on cuckoo's nests.

In the last two days my digestion is a bit better but accompanied by severe stomach pains that I know well from a full dose. Throughout the process they were rarely present and since the increase they seem to have returned with a vengeance.

The nights are haunted again, I wake up with less cortisol but more depression that quickly turns into a strong inner restlessness and almost zero ability to do the basics.

2 weeks almost since the increase and except for the burning sensation that has calmed down a bit, the rest is pretty much the same with a stronger than ever tinnitus. looking back, I might have managed to carry on and not be tempted to go up but what's done is done.

Now it's a long waiting time as I do my best to be patient and remind myself constantly that this is all chemical madness that will eventually pass.

Edited by Fullhealing

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

5 minutes ago, Fullhealing said:

Now it's a long waiting time as I do my best to be patient and remind myself constantly that this is all chemical madness that will eventually pass.

And that's the key my friend. Give your system a chance to regain its balance and calm itself down. We all know by now healing comes in its own way and in its own good time. Be kind to yourself and distract when you can!

Started Paxil for GAD in 1999

Unsuccessful taper attempt in 2006

Paxilprogress helped with a successful taper completed in 2009

Using therapy and CBT to manage my anxiety
 

I offer advice based on my experience.  Nothing I share is intended to be medical or therapy advice. 

19 minutes ago, Fullhealing said:

Update 28.08.26 1am

So today, while I'm in a flare-up with extreme restlessness I find myself humming with pleasure, bursting out laughing to some funny shorts only to cry my heart out and fall into atomic depression, irrational fears and unexplained rage a second later.. full on cuckoo's nests.

In the last two days my digestion is a bit better but accompanied by severe stomach pains that I know well from a full dose. Throughout the process they were rarely present and since the increase they seem to have returned with a vengeance.

The nights are haunted again, I wake up with less cortisol but more depression that quickly turns into a strong inner restlessness and almost zero ability to do the basics.

2 weeks almost since the increase and except for the burning sensation that has calmed down a bit, the rest is pretty much the same with a stronger than ever tinnitus. looking back, I might have managed to carry on and not be tempted to go up but what's done is done.

Now it's a long waiting time as I do my best to be patient and remind myself constantly that this is all chemical madness that will eventually pass.

Walking alongside you dear @Fullhealing .

Time and patience are our allies, just so hard when you can barely function. I share your night time depression, haunting and cortisol. What a contradictory combination. Activated / agitated , yet depressed as well. No wonder it feels like we are going mad.

Love to Jackie and your other fur kids xx

Aug 2006 - Sertraline 25/50/75/100mg TO June 2019 - Reduced from 100mg to 50mg over a few months

Sept  2019 - Reduced from 50mg to 25mg lasted a week,  then went back up to 50mg, after a few weeks back up to 100mg.

Oct 2021 - Reduced to 75mg, Dec 2021 (mid) reduced to 50mg , March 2022 - Reduced to 25mg

Oct 2022 - Reduce to 0mg (Immediate withdrawal crying, mood unstable, impending doom, digestive probs, tingling,numbness,burning, brain zaps,  insomnia)

Feb 2023 -  "Panic attack" lasting 14 hours, 2 weeks later start back on 25mg sertraline, 12 hours later severe 'panic attack' with chest pain, tachycardia, restlessness, hyponatraemia, impending doom, racing thoughts, akathisia mild.  Taken to emergency. 

March 2023 back up to 50mg (on medical advice), April 75mg, May 100mg. Back to 75mg within a few weeks due to feeling too stimulated and anxious. 

Nov 2023 resume taper. 70, 65, 60, 55, 50 (March 2024)

April 45mg, May 41mg, June 37mg, July 34mg Aug 31mg, Sept 28mg, Oct 26mg, Nov 25mg, HOLD 

Jan 1st 2025 24mg, Jan 12th 23.5mg, Jan 20th 23mg, Feb 20th 22mg, March 20th 21mg, April 14th 18.9mg, May 5th 17mg, May 28th 15.3mg, July 16th 13.7mg, Aug 26th 12.3mg, Sept 16th 10.5 mg, Sept 22, 10mg, Oct 7th 8.3mg, Nov 4th 8mg, Dec 1st 7.7mg, Dec 26th 7mg 2026 Updose to 7.2mg Mar 20th, Back to 7mg Mar 21. Currently holding

 

Other supplements: Fish oil, Mg citrate/glycinate 150-300mg per day, Ginkgo biloba daily, womens multi vit/min 3 times week, Vitamin C 1000mg night, valerian/passiflora as needed. B12 as needed. Bone support for osteopaenia (Ca/Mg, K, D)

1 hour ago, Fullhealing said:

full on cuckoo's nests.

You made me chuckle (the situation isn’t at all funny, but your description is ☺️)

I can relate… unfortunately

Lots of love and patience ❤️

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

 

 

  • Author
1 hour ago, Tracey said:

Walking alongside you dear @Fullhealing .

Time and patience are our allies, just so hard when you can barely function. I share your night time depression, haunting and cortisol. What a contradictory combination. Activated / agitated , yet depressed as well. No wonder it feels like we are going mad.

Love to Jackie and your other fur kids xx

I'm sorry we were forced to walk this path but if anything, I'm grateful to have you by my side.

I hope you're feeling a little better today dear @Tracey

Love back from me and all my ferries xxx

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

  • Author
51 minutes ago, Finni said:

You made me chuckle (the situation isn’t at all funny, but your description is ☺️)

I can relate… unfortunately

Lots of love and patience ❤️

Glad you smiled lol we much keep the black humor in check..

Hope you're doing a bit better today Finni, big hug xxx

Edited by Fullhealing

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

3 hours ago, Fullhealing said:

I'm sorry we were forced to walk this path but if anything, I'm grateful to have you by my side.

I hope you're feeling a little better today dear @Tracey

Love back from me and all my ferries xxx

Ditto to grateful for meeting you and the other wonderful people on here. xxx

Aug 2006 - Sertraline 25/50/75/100mg TO June 2019 - Reduced from 100mg to 50mg over a few months

Sept  2019 - Reduced from 50mg to 25mg lasted a week,  then went back up to 50mg, after a few weeks back up to 100mg.

Oct 2021 - Reduced to 75mg, Dec 2021 (mid) reduced to 50mg , March 2022 - Reduced to 25mg

Oct 2022 - Reduce to 0mg (Immediate withdrawal crying, mood unstable, impending doom, digestive probs, tingling,numbness,burning, brain zaps,  insomnia)

Feb 2023 -  "Panic attack" lasting 14 hours, 2 weeks later start back on 25mg sertraline, 12 hours later severe 'panic attack' with chest pain, tachycardia, restlessness, hyponatraemia, impending doom, racing thoughts, akathisia mild.  Taken to emergency. 

March 2023 back up to 50mg (on medical advice), April 75mg, May 100mg. Back to 75mg within a few weeks due to feeling too stimulated and anxious. 

Nov 2023 resume taper. 70, 65, 60, 55, 50 (March 2024)

April 45mg, May 41mg, June 37mg, July 34mg Aug 31mg, Sept 28mg, Oct 26mg, Nov 25mg, HOLD 

Jan 1st 2025 24mg, Jan 12th 23.5mg, Jan 20th 23mg, Feb 20th 22mg, March 20th 21mg, April 14th 18.9mg, May 5th 17mg, May 28th 15.3mg, July 16th 13.7mg, Aug 26th 12.3mg, Sept 16th 10.5 mg, Sept 22, 10mg, Oct 7th 8.3mg, Nov 4th 8mg, Dec 1st 7.7mg, Dec 26th 7mg 2026 Updose to 7.2mg Mar 20th, Back to 7mg Mar 21. Currently holding

 

Other supplements: Fish oil, Mg citrate/glycinate 150-300mg per day, Ginkgo biloba daily, womens multi vit/min 3 times week, Vitamin C 1000mg night, valerian/passiflora as needed. B12 as needed. Bone support for osteopaenia (Ca/Mg, K, D)

9 hours ago, Fullhealing said:

constantly that this is all chemical madness that will eventually pass.

This is it my friend 100%, nothing lasts forever. Good to see the symptoms waxing and waning, brain is fighting for stablity.....

👊

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

13 hours ago, Fullhealing said:

Update 28.08.26 1am

So today, while I'm in a flare-up with extreme restlessness I find myself humming with pleasure, bursting out laughing to some funny shorts only to cry my heart out and fall into atomic depression, irrational fears and unexplained rage a second later.. full on cuckoo's nests.

In the last two days my digestion is a bit better but accompanied by severe stomach pains that I know well from a full dose. Throughout the process they were rarely present and since the increase they seem to have returned with a vengeance.

The nights are haunted again, I wake up with less cortisol but more depression that quickly turns into a strong inner restlessness and almost zero ability to do the basics.

2 weeks almost since the increase and except for the burning sensation that has calmed down a bit, the rest is pretty much the same with a stronger than ever tinnitus. looking back, I might have managed to carry on and not be tempted to go up but what's done is done.

Now it's a long waiting time as I do my best to be patient and remind myself constantly that this is all chemical madness that will eventually pass.

Hang in there. We will get out of this. I'm also doing another long hold....

08/01/2009- Klonopin 1mg, but took only .25mg when needed, and end up taking every day for 3 years. 08/01/2012 - Paraxotine 20 mg

12/2024- reinstated 5mg (.0740g)after cold turkey. First tapering 07/01/2025 = 1.2% , 09/01/2025 - another 1.4%. 10/01/2025- 4.79mg (.0716g) holding until further notice........04/17/26 resumed taper 0714g (4.78mg). 05/20/2026- .0712g (4.76mg, .28% cut). 06/09/2026- .0708g (4.73mg .56% cut). 06/30/2026 - .0706g (4.72mg .33%). 07/28/2026 - .0700g (4.68mg, .85%).09/01/26 - .0698g (4.66mg, .29%).

  • Author
4 hours ago, Raymond said:

Hang in there. We will get out of this. I'm also doing another long hold....

Good thing, Raymond. We wouldn't want to fan the flames—they burned down almost my entire forest...

Now for the long wait... Reserving a front-row seat for you (;

I hope you have a great weekend!

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

  • Author

Update 01.09.26 12:30pm

Things continue to be turbulent following the excessive reduction and dosage increase, yesterday was a particularly grueling day, marked by a power outage that lasted from early morning until the early evening which delayed my daily dose by six hours triggering a massive headache and piercing deafening tinnitus all against the backdrop of a scorching 32 degree and humidity that felt like 200%, cruel combo..

Nights remain sweaty and haunted with abrupt awakenings straight into a terrifying and utterly exhausting twilight zone of chemical-like dread yet looking on the bright side I'm sleeping enough, perhaps even too much, something others surely yearn for so I must be grateful for that!

Recent symptoms, fluctuating in intensity, include:

* Intense burning sensations starting in the head and spreading to the arms, chest, and pelvic region.

* Rapid heart palpitations accompanied by air hunger.

* Gastrointestinal distress: severe heartburn, bloating, poor digestion, and stomach pain.

* Dizziness accompanied by the sensation of an electrical current whirring inside the head.

* Neurological tics and lateral eye squinting which initially appeared occasionally upon starting the medications years ago but have now become an almost daily occurrence.

* Catastrophic intrusive thoughts: terror,

anxiety, and paranoia.

* Intolerance to noise and light.

* Massive hair loss, desert-dry skin.

* Extreme fatigue.

* Profound apathy and a complete lack of motivation or desire, essentially depression.

Undoubtedly some of this is exacerbated by low ferritin, vitamin D, and B12 levels, compounded by perimenopause which began over the last eight months (or perhaps earlier, though I only recently had clear indications) which need a checking however, given my current state I simply lack the energy to go get it done, the discomfort, to put it very mildly, that doctors tend to cause doesn't help motivate me either but this must be addressed and I will somehow have to force myself..

So, we shall see what's next, for now I'm still housebound having officially been out of work for about 3.5 weeks, had to stop my short evening walks due to my intolerances for people, tho it is important to gently push, one must equally know when to ease off the gas pedal during certain times, something I trying to accept with grace as challenging as that may be.

So the big war for absolute freedom of these dreadful toxins continues with most likely many exhausting battles but at our own individual paces we will all get there.

Edited by Fullhealing

1998 forced on cipramil *no anxiety/depression background*

Over the years all kinds of SSRI/SNRI/antipsychotics/stabilizers due to apparently side effects/withdrawal

Many attempts to quit over the years with failure (extremely rapid taper followed by doctors' guidens)

Current attempt-Paxil 20 mg:

6/24 20 mg to 5 mg-severe AKA

9/24 Increase to 20-AKA continues

10/24 stopped completely-AKA out of control 

11/24 Zoloft bridge attempt-25 mg to 75 mg+Seroquel-AKA continued-stopped them CT.

12/24 Back on Paxil 10mg (0.1789g)-some stabilization-from here tapered by about 30% each time (don't remember doses and dates).

2025 - 7.10 0.0558g (3.11mg)/7.11 3% 0.0541g (3.02mg)/4.12 1% 0.0535g (2.98mg)

2026 - 3.1 1.5% 0.0526g (2.93mg)/9.1 8.5% 0.0480g (2.68mg)/16.2 1.8% 0.0470g (2.62mg)/21.3 1% 0.466 (2.60mg)/23.4 2.2% 0.455g (2.54mg)/8.7 21.7% 0.0356.5g (2mg)/15.8 updose by 11.7% 0.0400g (2.23mg)

Supplements:

Magnesium Glycinate - started 28.5.26 1 capsule 200mg in the morning - Increased brain fog and muscle stiffness - stopped after two weeks.

Iron - liquid, quarter of recommended dose - increased anxiety and burning sensation - stopped after two weeks.

Saffron - started 8.7.26 1 capsule 30mg in the morning - pretty immediate improvement in terms of terror, body pain and sleep.

What a terrible symptom list…I am so sorry 😦.

2 hours ago, Fullhealing said:

So the big war for absolute freedom of these dreadful toxins continues with most likely many exhausting battles but at our own individual paces we will all get there.

Love this. Yes, absolute freedom. That’s what we are heading towards. And we will all get their, together we will.

Thinking of you and sending peace and strength your way. ❤️

SA Thread: https://www.survivingantidepressants.org/forums/topic/33406-nemina-tapering-escitalopram/


AR Thread: https://antidepressantrecovery.org/topic/14-nemina-tapering-escilatopram-and-zolpidem/

 

Drug History

2013 - 2025:  Zolpidem 5 mg

2015 - Oct 2024: Venlafaxine, Sertralin (Zoloft), Paroxetin (Paxil),duloxtin (cymbalta), Citalopram (Celexa), Escitalopram (Lexapro) and more 

 

Current Drugs

L-Thyroxin 75, Estrogen, Progesteron 200

 

Tapering Escitalopram

Until Sept 2024: Setralin/zoloft 75 mg

Oct 2024: Switch to Escitalopram / Lexapro 2mg

Then I tapered over a year from 2mg to 0,32 mg (October 2025).  108 days hold without stabilizing. Resumed taper February 2026:

11 Feb 2026 0.314mg 

18 Feb 2026 0.307mg 

21 Feb 2026 0.302mg

09 Mar 2026 0.297mg

18 April 2026 0,293 mg

18 May 2026 0,285 mg

18 June 2026 0,265 mg

18 July 2026 0,250 mg

18 Aug 2026 0,232 mg

 

Tapering Zolpidem: From 5 mg to 0,7 mg in 12 months,  then just crumbs for several weeks, now 0! (Jan 2025)

 

Other Supplements 

Omega 3, Magnesium Glycinate, Vit D, Calcium, L-theanin.

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