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Finni: Sensitized by Many Med changes and Mirtazapine

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4 hours ago, Finni said:

It’s the middle of the night

I felt the cut

Can’t believe this

It’s terrifying

I’m realizing I should not have made any changes because of the stress I’ve been under. When it feels paradoxical, it’s just so hard not to.

My mom fell and broke her hip two days ago and is in the hospital.

I’m sorry @Finni 💜. I hope your mom recovers quickly.

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. 

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

 

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

 

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  • Author

I think my body was probably actually starting to regulate because I was doing that every other day pattern. Maybe that was a sign.

I hope I haven’t set myself too far back

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

4 hours ago, Finni said:

I think my body was probably actually starting to regulate because I was doing that every other day pattern. Maybe that was a sign.

I hope I haven’t set myself too far back

Finni , how is your Mom doing, better I hope. I don't think you set yourself back, it's probably just you system getting used to the drop. You are doing amazing, and are so strong, just hold for a few bumps here and there, you got this.😊

Dec 23 Citalopram 15mg

13 March 24 13.5mg

27 March 24 10mg

12 March 24 7.5mg

20 March 24 6mg

10 Aug 24 5mg

24 Aug 24 4mg

2 Sept 24 3.5mg

11 Sept 24 3mg

19 Sept 24 2.5mg

26 Sept 24 2mg

5 Oct 24 1.5mg

12 Oct 24 1mg

17 Oct 24 Jumped off.

  • Author

I have to learn the hardest lessons during this most hideous journey

I took off such a very small amount three nights ago that I didn’t think it would be any big deal just to go back to where I was because my body reacted so violently to that very small change

Unfortunately, now the adverse effects seem to be more adverse

I keep doing these things because it’s so hard for me to imagine that these tiny changes are creating such a huge effect

I had so much electricity in my body after I reduced a little bit with really severe body responses like muscles are getting super tight vocalizing from all the overwhelm, akasthisia.

After I took my usual dose again, two nights ago, I hardly slept because I was so activated and shaking like it didn’t even more of a number on me

I ended up going to an emergency room and then to a crisis center, just because I was so scared

Now I’ve had two doses of my usual .1026 g and of course I regret it now I wish I would’ve just stayed at .1024 g but at the time that withdrawal reaction was so strong that I just went right back up

I thought I might not even feel that little tiny drop to 1.024 g

The floatiness, dizziness and aka is worse than it’s been in a long, long time

What in the hell do I do now now that it’s even worse?

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

Hi @Finni im sorry you are not feeling well. How much of a milligram drop was that?

I hope you feel better soon.

1998 -1999 Paxil CT after 5 months.

1999 - 2024 every 2 to 4 years went from one SSRI to the next. That includes Luvox, Zoloft, Cymbalta, Celexa, Prozac, Lexapro.

2000-2024 lorazepam 2mg.

April 2024 one dose of Effexor, July 2024 one dose of Paxil, July 2024 two weeks of Mirtazapine. September 2024 Lexapro 10mg, Depakote 250mg, Vistaril 25 mg ,Proppranolol 10mg, Requip 2mg Trazadone 50mg. March 2025 off Depakote,Propranolol,vistaril,Trazadon.

March 2025 Zyprexa added at 2.5 mg.”for sleep and anxiety”. Went up to 7.5mg in June.

September 2025 started tapering Zyprexa and Requip.

February 2026 off of Zyprexa and Requip. Reduced Lexapro to 5mg

7/4/2026-4.5mg

8/1/2026-4.0mg

  • Author

I think I downplayed what was going on with my mom and how that stressed out my nervous system even more and it was not the time to try to reduce no matter how small or micro I thought it was

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

  • Author

I’m so scared. I don’t know what to do. I feel like I have heat all over my body and my blood pressure is much higher than normal.

It was high in the emergency room and it was high at the crisis center too

My blood pressure has been running on the low side, but now it is in the moderate range

150s yesterday

140s today

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

I i’m so sorry for your suffering. I think that stressful events in life produce a much stronger reaction during withdrawal than if we were in a normal situation. Maybe it was not the reduction, but just the stress you are experiencing right now. Now it’s not the time to worry about whether the reduction was too big, you better concentrate on calming down and on acceptance. You will probably be able to reduce your dose when you are not stressed out by life so much.

I send you my best wishes, strength, and peace.

SA Thread: https://www.survivingantidepressants.org/forums/topic/33406-nemina-tapering-escitalopram/


AR Thread: https://antidepressantrecovery.org/topic/14-nemina-tapering-escilatopram-and-zolpidem/

 

Drug History

2013 - 2025:  Zolpidem 5 mg

2015 - Oct 2024: Venlafaxine, Sertralin (Zoloft), Paroxetin (Paxil),duloxtin (cymbalta), Citalopram (Celexa), Escitalopram (Lexapro) and more 

 

Current Drugs

L-Thyroxin 75, Estrogen, Progesteron 200

 

Tapering Escitalopram

Until Sept 2024: Setralin/zoloft 75 mg

Oct 2024: Switch to Escitalopram / Lexapro 2mg

Then I tapered over a year from 2mg to 0,32 mg (October 2025).  108 days hold without stabilizing. Resumed taper February 2026:

11 Feb 2026 0.314mg 

18 Feb 2026 0.307mg 

21 Feb 2026 0.302mg

09 Mar 2026 0.297mg

18 April 2026 0,293 mg

18 May 2026 0,285 mg

18 June 2026 0,265 mg

18 July 2026 0,250 mg

18 Aug 2026 0,232 mg

18 Sept 2026 0,232 mg (Holding since 19.8.)

 

Tapering Zolpidem: From 5 mg to 0,7 mg in 12 months,  then just crumbs for several weeks, now 0! (Jan 2026)

 

Other Supplements 

Omega 3, Magnesium Glycinate, Vit D, Calcium, L-theanin, Vit C, Vit K2, Selen

Sorry to hear you’ve reacted so badly to a micro reduction @Finni . I’m in a similar position. I’ve been on the same dose foe 3 months and my body reacts when I try to drop by 2 micrograms . I’m just going to leave things be for another 2 months. I feel like there’s some invisible force twisting all the muscles in my abdomen. It’s incapacitating 😢

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg.  2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day) 

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

  • Author

I’m so sorry @Catbird ❤️

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

@Finni just catching up with your thread. So you tried a small reduction for a few days and it did not go well so you updosed back up again?

Sounds like this is the eviedence you need that holding your dose is the right move, but I agree additional stress can make things worse too so this may well have been part of how you are feeling too.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

@Chippy

Yes- I thought surely a tiny reduction wouldn’t do much…, an amount not even perceptible on most scales.

When my body reacted so violently, I just went back the next night

.1024 g back to .1026 g

Now I’m having to go through horrible painful pounding twisting electricity and pressure in a new level

Totally flabbergasted and terrified

The place where I’d gotten was so much better than this! I didn’t realize how far I had come, but if I would’ve stopped to really look at my ratings every day, I would’ve seen that. But what I saw was “oh I think I’m better enough to take this teeny teeny tiny bit off.”

When I’m convinced I’m having paradoxical and adverse reactions, It’s so hard to do nothing.

Edited by Finni

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

  • Author

CBD? Does anybody has anybody tried it for nerve pain or horrible physical symptoms? I’m in almost unbearable. Excruciating pain.

Update: a ginger chew helped with pain

Now just crushing pressure

Edited by Finni

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

18 hours ago, Finni said:

CBD? Does anybody has anybody tried it for nerve pain or horrible physical symptoms? I’m in almost unbearable. Excruciating pain.

Update: a ginger chew helped with pain

Now just crushing pressure

I am sorry Finni, hope it eased a bit for you. Glad the Finer chew helped, I would not try the CBD, fuel on the fire IMO, xxx

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

19 hours ago, Finni said:

CBD? Does anybody has anybody tried it for nerve pain or horrible physical symptoms? I’m in almost unbearable. Excruciating pain.

Update: a ginger chew helped with pain

Now just crushing pressure

@Finni LDN has worked over the years for me, but not recently for the abdominal myofascial pain that has been plagued me more recently. CBD does nothing noticeable for me.

Link to SA Profile: https://www.survivingantidepressants.org/forums/topic/32414-catbird-introduction-a-long-and-winding-road/

1996 Commenced on Sertraline 50 - 100mg. Many ADs trialled -Fluoxetine 20 mg, Paroxetine 20mg, Venlafaxine 75mg, Escitalopram 10 - 20mg, Vortioxetine 20mg, Bupropion 150mg.  2019 Recommenced Escitalopram 2022 Mirtazapine 30mg - Rapid taper. Amitriptyline 20mg

CURRENT MEDICATIONS: Escitalopram taper from ~ 10mg commenced 2024, Amitriptyline 20mg at night, Diazepam 7.5mg total per day, Baclofen 10mg morning, 10mg lunch and 20mg night, Polaramine 2mg at night, Ketamine troche 25mg per day (Ceased early September 2025), Valsartan 160mg evening, HRT (Oestrogen 25mcg/day) 

ESCITALOPRAM TAPER: 5 April 2025 - started holding at 1.516mg. Escitalopram taper resumed July 2025; End Aug 1.364; End Sept 1.228; End Oct 1.145; End Nov 1.1 Early Dec 1.11; End Dec 1.082; 2026 End Jan 1.047; Feb 6 1.030; Feb 20 1.014; April 10 1.012; May 3 1.014; May 11 1.020 & still holding; Sept 19 1.014; Oct 4 1.006; Oct 8 1.010

Supplements: Mg++ glycinate, Omega 3s, Curcumin. Vit D3/K2 spray, Vitamin B12 spray, chelated zinc.

  • Author
16 hours ago, Finni said:

I’m so sorry @Catbird ❤️

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

  • Author

5:00 am

The every other day swings from cold turkey feeling to floaty and sick continue, only now the floaty and sick comes with inner and external akasthisia and elevated blood pressure. Cold turkey violent withdrawals.

The day before I tried the tiny drop I felt so sick and out of it, and that prompted me to go ahead, not realizing the violent reaction that was coming.

This morning after a violent withdrawal day, I feel very sick, have huge vestibular symptoms, and can feel the aka motor revving up. Intensely nervous and weird.

Hands shaking.

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

3 hours ago, Finni said:

5:00 am

The every other day swings from cold turkey feeling to floaty and sick continue, only now the floaty and sick comes with inner and external akasthisia and elevated blood pressure. Cold turkey violent withdrawals.

The day before I tried the tiny drop I felt so sick and out of it, and that prompted me to go ahead, not realizing the violent reaction that was coming.

This morning after a violent withdrawal day, I feel very sick, have huge vestibular symptoms, and can feel the aka motor revving up. Intensely nervous and weird.

Hands shaking.

Thinking about you @Finni 💜💜💜

I’m not a medical professional and cannot offer medical advice. I am new to this journey and my thoughts are based only on my personal experience with psychiatric drugs. This is a peer site where we support each other on our taper/recovery journeys. 

Current regimen:

Cymbalta - 90 mg/day

Seroquel - 12.5 mg/day

*holding to stabilize as of Apr 2026

 

History:

Seroquel - up to 50 mg as needed for sleep (generally 6.25-12.5 mg a few times a week, though sometimes more) - 2009 (ish) to present

Cymbalta - 60 mg/day, periodically down to 30 mg/day - May 2014 to May 2025

Clonazepam - up to 1 mg/day as needed - March to May 2025, quick taper off

Zoloft - 150 mg/day - May 2025 to Aug 2025 (quick cross-taper from Cymbalta)

Pristiq - 50 mg/day from Aug 2025 to mid-Oct 2025 (quick cross-taper from Zoloft); 100 mg/day from Oct 2025 to Dec 2025; back down to 50 mg/day from Dec 2025 to Jan 2026

Lyrica - 200 mg/day - Nov 2025 to Jan 2026 (quick taper off from mid-Jan to early Feb 2026 due to severe depressive symptoms)

Cymbalta - 60 mg/day - Jan - March 2026; up to 90 mg/day from March to present

 

  • Author

7/27/26

Blood pressure my usual

Low normal range

I was just assuming it was going to be high again like day before yesterday when I felt overmedicated.

Terror surges and crazy floaty rocking with deep electricity my main symptoms today

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

Finni, sorry to hear you going through this wave, my thoughts and heart goes out to you for some much needed relief, just know this will pass as unpleasant as it my feel. Hugs🤗

Dec 23 Citalopram 15mg

13 March 24 13.5mg

27 March 24 10mg

12 March 24 7.5mg

20 March 24 6mg

10 Aug 24 5mg

24 Aug 24 4mg

2 Sept 24 3.5mg

11 Sept 24 3mg

19 Sept 24 2.5mg

26 Sept 24 2mg

5 Oct 24 1.5mg

12 Oct 24 1mg

17 Oct 24 Jumped off.

  • Author
8 minutes ago, Bernadette said:

Finni, sorry to hear you going through this wave, my thoughts and heart goes out to you for some much needed relief, just know this will pass as unpleasant as it my feel. Hugs🤗

Thank you 🤗

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

  • Author
14 hours ago, Chippy said:

I am sorry Finni, hope it eased a bit for you. Glad the Finer chew helped, I would not try the CBD, fuel on the fire IMO, xxx

Thanks, Chippy 🩵

I think the next thing for me to do is to split my dose since it’s so activating and I feel it so acutely as it’s wearing off in the afternoon and evening.

The question is how far past this last disruption do I need to wait before I try?

I know I’ve asked this question before, but I feel like I’m even more sensitized now.

Another thing- One time Mark said I should take 1 mg earlier and earlier and another time said I could take 3 mg earlier and earlier.

I wonder why the difference?

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

9 hours ago, Finni said:

Thanks, Chippy 🩵

Always here for you dear Finni x

9 hours ago, Finni said:

I think the next thing for me to do is to split my dose since it’s so activating and I feel it so acutely as it’s wearing off in the afternoon and evening.

You have to do what you think is right

9 hours ago, Finni said:

The question is how far past this last disruption do I need to wait before I try?

You know my feelings on changes, sometimes they are needed but often I think they become excuses to try to 'fix'

9 hours ago, Finni said:

Another thing- One time Mark said I should take 1 mg earlier and earlier and another time said I could take 3 mg earlier and earlier.

I wonder why the difference?

I think he was just suggesting taking a % of your dose and splitting it. Perhaps he changed his 'rule of thumb' between talking to you. It is all guess work. So little research.

I’m not a medical professional and cannot offer medical advice. I only offer my thoughts as support. Please speak to your health practitioner about your care. This is a peer site where we support each other on our taper/recovery journeys. 

 

If you are from the UK please make sure you fill in a 'Yellow Card' report for the MHRA. It is you doing your bit to help make a difference.

Please take the time to do it today 🙂 https://yellowcard.mhra.gov.uk

For US members details here.

  • Author

From ChatGPT

My nervous system is sunburned. It can make ordinary signals feel enormous. Time is on my side. ☀️

Edited by Finni

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

  • Author

@Lighty

Have you posted something about mindset on this forum?

For US members: Please report med to FDA Med Watch

2017 (May) - Ativan .5 mg (3 x Daily) 

2018 (Feb) - Mirtazapine 7.5 mg 

2018 (May) - Ativan to Valium - Switch - Can’t Remember how long it took -tapered to 3 mg of Valium

2024 (May) - Valium Tolerance

2024 (2 Nov) - Completed taper off Valium 

2024 (2 Nov) - Mirtazapine increased to 15 mg

2025 (Feb) - Ativan 0.25 mg (3 x Daily) - Became Paradoxical - Started weaning got to 0.11mg

2025 (Mar) - Ativan 0mg - CT In detox

2025 (April) Started Depakote 1500mg - In detox

2025 (April) - Depakote 500mg (2 x Daily) once home

2025 (Aug) - Completed taper off Depakote

2025 (Aug) - Akathisia surges throughout the day with calming in between

2025 (Sept) - Gabapentin (Micro Dose) - Was calming at first and then became paradoxical so stop

2025 (Oct) - Depakote - RI – (Two days of small dose) Became scared and stopped with WD & aka

2025 (Oct) - Seroquel 50 mg XR – 1 Week - more and more activating and increased aka

2025 (Oct) - Psychiatrist told me to stop it. But I took a few days of a smaller dose of IR then stopped - Not activating

2025 (Nov) - Hydroxyzine 2.5mg - it was paradoxical so stopped

2025 (1 Dec) - Mirtazapine 22.5mg - (2 Days) Was incredibly overstimulating started reducing to previous

2025 (3 Dec) - Mirtazapine 18.75mg

2025 (10 Dec) - Mirtazapine 16.87mg

2025 (22 Dec) - Mirtazapine 15mg

2026 (23Jan) - Mirtazapine 14.7mg

2026 (23 Jan) - Mirtazapine 1mg Panic dose

2026 (24 Jan) - Mirtazapine 15mg

2026 (25 Feb) – Mirtazapine 14.7mg (-2%)

2026 (18 Mar) - propranolol 2.5 mg one time

2026 (21 Mar)- Mirtazapine- 15 mg accidentally in sleepy state

2026 (22 Mar) - Mirtazapine 14.79 mg (more accurate scales) 

2026 (29 April) Mirtazapine 14.7 mg/.1020 g (on suggestion of Horowitz) immediate intense symptoms

2026 (30 April) Mirtazapine 14.79 mg (.1026 g)

2026 (23 May) propranolol 2.5 mg one time

2026 (01 June) Mirtazapine 14.79 mgdose was 5 hours late

2026 (22 July) Mirtazapine 14.76 mg

Intense electric activation, muscle tightness, autonomic surges, terror followed

2026 (23 July) Mirtazapine 14.79 mg return

2026 (Oct 5) attempted moving 2 mg of dose 45 minutes earlier

Severe activation followed

 

 

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